Pre-hospital hypothermia is not associated with increased survival after traumatic brain injury

Journal of Surgical Research

Volumn 175, Issue 1, 2012, Pages 24-29

  Bukur, Marko ^a   Kurtovic, Silvia ^a   Berry, Cherisse ^a   Tanios, Mina ^a   Ley, Eric J ^a   Salim, Ali ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

mortality; outcomes; pre hospital hypothermia; traumatic brain injury

Indexed keywords

ADULT; ARTICLE; BLUNT TRAUMA; BODY TEMPERATURE; CONTROLLED STUDY; EMERGENCY WARD; FEMALE; GLASGOW COMA SCALE; HOSPITAL ADMISSION; HUMAN; HYPOTENSION; HYPOTHERMIA; IN VITRO STUDY; IN VIVO STUDY; INJURY SEVERITY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; SURVIVAL; THERMOREGULATION; TRAUMATIC BRAIN INJURY;

ADOLESCENT; ADULT; AGED; BRAIN INJURIES; DATABASES, FACTUAL; FEMALE; GLASGOW COMA SCALE; HUMANS; HYPOTHERMIA; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 84860338502     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.07.003     Document Type: Article

References (58)

1. P. Enriquez, and R. Bullock Molecular and cellular mechanisms in the pathophysiology of severe head injury Curr Pharm Des 10 2004 2131
2. S.L. Bratton, R.M. Chesnut, and J. Ghajar Blood pressure and oxygenation J Neurotrauma 24 2007 S7
3. G.J. Wang, H.Y. Deng, and C.M. Maier Mild hypothermia reduces ICAM-1 expression, neutrophil infiltration and microglia/monocyte accumulation following experimental stroke Neuroscience 114 2002 1081
4. J.Y. Jiang, W. Xu, and P.F. Yang Marked protection by selective cerebral profound hypothermia after complete cerebral ischemia in primates J Neurotrauma 23 2006 1847
5. M.P. Ehrlich, J.N. McCullough, and N. Zhang Effect of hypothermia on cerebral blood flow and metabolism in the pig Ann Thorac Surg 73 2002 191
6. C.M. Maier, G.H. Sun, and D. Cheng Effects of mild hypothermia on superoxide anion production, superoxide dismutase expression, and activity following transient focal cerebral ischemia Neurobiol Dis 11 2002 28
7. D. Demetriades, E. Kuncir, and C.V. Brown Early prediction of mortality in isolated head injury patients: A new predictive model J Trauma 61 4 2006 868
8. M. Ottochian, R. Benfield, and K. Inaba Prospective evaluation of a predictive model of mortality in patients with isolated head injury J Trauma 67 2009 81
9. E.Y. Fukudome, and H.B. Alam Hypothermia in multisystem trauma Crit Care Med 37 2009 s265
10. S. Steinemann, S.R. Shackford, and J.W. Davis Implications of admission of hypothermia in trauma patients J Trauma 30 1990 200
11. J.H. Walters, P.T. Morley, and J.P. Nolan The role of hypothermia in post-cardiac arrest patients with return of spontaneous circulation: A systematic review Resuscitation 82 2011 508
12. N. Cosgriff, E. Ernest, and A. Sauaia Predicting life-threatening coagulopathy in the massively transfused trauma patient: Hypothermia and acidosis revisited J Trauma 42 1997 857
13. S.A. Bernard, T.W. Gray, and M.D. Buist Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia N Engl J Med 346 2002 557
14. Hypothermia after cardiac arrest study group Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest N Engl J Med 346 2002 549
15. W.D. Dietrich, and H.M. Bramlett The evidence for hypothermia as a neuroprotectant in traumatic brain injury Neurotherapeutics 7 2010 43
16. M.Y. Globus, O. Alonso, and W.D. Dietrich Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia J Neurochem 65 1995 1704
17. J.Y. Jiang, Y.M. Liang, and Q.Z. Luo Effect of mild hypothermia on brain dialysate lactate after fluid percussion brain injury in rodents Neurosurgery 54 2004 713
18. B.G. Lyeth, J.Y. Jiang, and S.E. Robinson Hypothermia blunts acetylcholine increase in CSF of traumatically brain injured rats Mol Chem Neuropathol 18 1993 247
19. H. Koizumi, H. Fujisawa, and H. Ito Effects of mild hypothermia on cerebral blood flow-independent changes in cortical extracellular levels of amino acids following contusion trauma in the rat Brain Res 747 1997 304
20. J.Y. Jiang, B.G. Lyeth, and M.Z. Kapasi Moderate hypothermia reduces blood-brain barrier disruption following traumatic brain injury in the rat Acta Neuropathol 84 1992 495
21. K. Kinoshita, K. Chatzipanteli, and O.F. Alonso The effect of brain temperature on hemoglobin extravasation after traumatic brain injury J Neurosurg 97 2002 945
22. N. Arican, M. Kaya, and C. Yorulmaz Effect of hypothermia on blood-brain barrier permeability following traumatic brain injury in chronically ethanol-treated rats Int J Neurosci 116 2006 1249
23. W.L. Maxwell, S. Donnelly, and X. Sun Axonal cytoskeletal responses to nondisruptive axonal injury and the short-term effects of posttraumatic hypothermia J Neurotrauma 16 1999 1225
24. W.C. Taft, K. Yang, and C.E. Dixon Hypothermia attenuates the loss of hippocampal microtubule-associated protein 2 (MAP2) following traumatic brain injury J Cereb Blood Flow Metab 13 1993 796
25. J.R. Goss, S.D. Styren, and P.D. Miller Hypothermia attenuates the normal increase in interleukin 1 RNA and nerve growth factor following traumatic brain injury in the rat J Neurotrauma 12 1995 159
26. E.A. Vitarbo, K. Chatzipanteli, and K. Kinoshita Tumor necrosis factor expression and protein levels after fluid percussion injury in rats: The effect of injury severity and brain temperature Neurosurgery 55 2004 416
27. K. Chatzipanteli, K. Wada, and R. Busto Effects of moderate hypothermia on constitutive and inducible nitric oxide synthase activities after traumatic brain injury in the rat J Neurochem 72 1999 2047
28. J.S. Truettner, O.F. Alonso, and D.W. Dietrich Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats J Cereb Blood Flow Metab 25 2005 1505
29. K. Kinoshita, K. Chatzipanteli, and E. Vitarbo Interleukin-1 messenger ribonucleic acid and protein levels after fluid-percussion brain injury in rats: Importance of injury severity and brain temperature Neurosurgery 51 2002 195
30. G. Lotocki, J.P. de Rivero Vaccari, and E.R. Perez Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage Eur J Neurosci 24 2006 2283
31. C.D. Kemp, J.C. Johnson, and W.B. Riordan How we die: The impact of non-neurologic organ dysfunction after severe traumatic brain injury Am Surg 74 2008 866
32. D.A. Zygun, J.B. Kortbeek, and G.H. Fick Non-neurologic organ dysfunction in severe traumatic brain injury Crit Care Med 33 2005 654
33. D.S. Heffernan, K. Inaba, and S. Arbabi Sympathetic hyperactivity after traumatic brain injury and the role of beta-blocker therapy J Trauma 69 2010 1602
34. K.H. Polderman Induced hypothermia and fever control for prevention and treatment of neurological injuries Lancet 371 2008 1893
35. N. Badjatia Hyperthermia and fever control in brain injury Crit Care Med 37 2009 S250
36. K.H. Polderman, and I. Herold Therapeutic hypothermia and controlled normothermia in the intensive care unit: Practical considerations, side effects, and cooling methods Crit Care Med 37 2009 1101
37. G. Broessner, R. Beer, and P. Lackner Prophylactic endovascularly based, long-term normothermia in ICU patients with severe cerebrovascular disease: Bicenter prospective, randomized trial Stroke 40 2009 e657
38. C.M. Atkins, A.A. Oliva Jr., and O.F. Alonso Hypothermia treatment potentiates ERK1/2 activation after traumatic brain injury Eur J Neurosci 26 2007 810
39. A.K. Biswas, D.A. Bruce, and F.H. Sklar Treatment of acute traumatic brain injury in children with moderate hypothermia improves intracranial hypertension Crit Care Med 30 2002 2742
40. P.D. Adelson, J. Ragheb, and P. Kanev Phase II clinical trial of moderate hypothermia after severe traumatic brain injury in children Neurosurgery 56 2005 740
41. J.S. Hutchinson, R.E. Ward, and J. Lacroix Hypothermia therapy after traumatic brain injury in children N Engl J Med 358 2008 2447
42. G.L. Clifton, E.R. Miller, and S.C. Choi Lack of effect of induction of hypothermia after acute brain injury N Engl J Med 344 2001 556
43. O.A. Harris, J.M. Colford Jr., and M.C. Good The role of hypothermia in the management of severe brain injury: A meta-analysis Arch Neurol 59 2002 1077
44. W.R. Henderson, V.K. Dhingra, and D.R. Chittock Hypothermia in the management of traumatic brain injury. A systematic review and meta-analysis Intensive Care Med 29 2003 1637
45. P. Alderson, and I. Roberts Corticosteroids for acute traumatic brain injury Cochrane Database Syst Rev 2 2000 CD000196
46. L.A. McIntyre, D.A. Fergusson, and P.C. Hebert Prolonged therapeutic hypothermia after traumatic brain injury in adults: A systematic review JAMA 289 2003 2992
47. C.N. Sambasivan, and M.A. Schreiber Emerging therapies in traumatic hemorrhage control Curr Opin Crit Care 15 2009 560
48. B.H. Shaz, C.J. Dente, and R.S. Harris Transfusion management of trauma patients Anesth Analg 108 2009 1760
49. V.A. Eddy, J.A. Morris Jr., and D.C. Cullinane Hypothermia, coagulopathy, and acidosis Surg Clin North Am 80 2000 845
50. P. Talving, R. Benfield, and P. Hadjizacharia Coagulopathy in severe traumatic brain injury: A prospective study J Trauma 66 2009 55
51. T. Lustenberger, P. Talving, and L. Kobayashi Early coagulopathy after isolated severe traumatic brain injury: Relationship with hypoperfusion challenged J Trauma 69 2010 1410
52. K.H. Polderman, E.R. Rijnsburger, and S.M. Peerdeman Induction of hypothermia in patients with various types of neurologic injury with use of large volumes of ice-cold intravenous fluid Crit Care Med 33 2005 2744
53. A.W. De Hartog, A.C. de Pont, and L.B. Robillard Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: An observational cohort study Crit Care 14 2010 R121
54. th ed. 2008 American College of Surgeons Chicago, IL
55. H.E. Wang, C.W. Callaway, and A.B. Peitzman Admission hypothermia and outcome after major trauma Crit Care Med 33 2005 1296
56. G.S. McHugh, D.C. Engel, and I. Butcher Prognostic value of secondary insults in traumatic brain injury: Results from the IMPACT study J Neurotrauma 24 2007 287
57. B.M. Selladuri, M. Vickneswaran, and S. Duraisamy Coagulopathy in acute head injury - A study of its role as a prognostic indicator Br J Neurosurg 11 1997 398
58. J.B. MacLeod, M. Lynn, and M.G. McKenney Early coagulopathy predicts mortality in trauma J Trauma 55 2003 39