A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival

Journal of Immunology

Volumn 188, Issue 8, 2012, Pages 3920-3927

  Choi, Onjee ^a   Heathcote, Dean A ^a   Ho, Ka Kei ^a   Müller, Phillip J ^a   Ghani, Hazim ^a   Lam, Eric W F ^a   Ashton Rickardt, Philip G ^a   Rutschmann, Sophie ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYCYTIDINE KINASE; ETHYLNITROSOUREA; HERMES ANTIGEN; L SELECTIN; NUCLEOSIDE;

ADOPTIVE TRANSFER; ALPHA HELIX; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BLOOD CELL COUNT; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; DORMANCY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME REGULATION; ERYTHROCYTE; GENE MUTATION; HEMATOPOIETIC SYSTEM; HOMEOSTASIS; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE QUIESCENCE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTOPENIA; LYMPHOCYTOPOIESIS; MOUSE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLENOMEGALY; T LYMPHOCYTE; WILD TYPE;

ANIMALS; ANTIGENS, CD; APOPTOSIS; B-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; DEOXYCYTIDINE KINASE; ERYTHROCYTES; ETHYLNITROSOUREA; GENE SILENCING; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOPENIA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; MYELOID CELLS; NUCLEOSIDES; SEQUENCE ANALYSIS, DNA; T-LYMPHOCYTES;

EID: 84860321945     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102587     Document Type: Article

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