메뉴 건너뛰기




Volumn 40, Issue 11, 2010, Pages 3043-3053

Apoptosis regulators fas and bim synergistically control t-lymphocyte homeostatic proliferation

Author keywords

Apoptosis; Homeostatic proliferation; T lymphocyte

Indexed keywords

BIM PROTEIN; FAS ANTIGEN; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; FAS PROTEIN, MOUSE; HISTOCOMPATIBILITY ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 7; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; ONCOPROTEIN; PEPTIDE;

EID: 79551636079     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040577     Document Type: Article
Times cited : (15)

References (51)
  • 1
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst, B., Lee, D. S., Chang, J. M., Sprent, J. and Surh, C. D., The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 1999. 11: 173-181.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 2
    • 0033180494 scopus 로고    scopus 로고
    • Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
    • Goldrath, A. W. and Bevan, M. J., Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 1999. 11: 183-190.
    • (1999) Immunity , vol.11 , pp. 183-190
    • Goldrath, A.W.1    Bevan, M.J.2
  • 3
    • 0001585396 scopus 로고    scopus 로고
    • Control of homeostasis of CD8+ memory T cells by opposing cytokines
    • Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J. and Marrack, P., Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science 2000. 288: 675-678.
    • (2000) Science , vol.288 , pp. 675-678
    • Ku, C.C.1    Murakami, M.2    Sakamoto, A.3    Kappler, J.4    Marrack, P.5
  • 4
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns, K. S., Kieper, W. C., Jameson, S. C. and Lefrancois, L., Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 2000. 1: 426-432.
    • (2000) Nat. Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 5
    • 57449097558 scopus 로고    scopus 로고
    • Homeostasis of naive and memory T cells
    • Surh, C. D. and Sprent, J., Homeostasis of naive and memory T cells. Immunity 2008. 29: 848-862.
    • (2008) Immunity , vol.29 , pp. 848-862
    • Surh, C.D.1    Sprent, J.2
  • 6
    • 0030249953 scopus 로고    scopus 로고
    • MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span
    • Takeda, S., Rodewald, H. R., Arakawa, H., Bluethmann, H. and Shimizu, T., MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity 1996. 5: 217-228.
    • (1996) Immunity , vol.5 , pp. 217-228
    • Takeda, S.1    Rodewald, H.R.2    Arakawa, H.3    Bluethmann, H.4    Shimizu, T.5
  • 7
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naive or memory T cells
    • Tanchot, C., Lemonnier, F. A., Perarnau, B., Freitas, A. A. and Rocha, B., Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 1997. 276: 2057-2062.
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 8
    • 0033136944 scopus 로고    scopus 로고
    • Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition
    • Viret, C., Wong, F. S. and Janeway, C. A., Jr., Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition. Immunity 1999. 10: 559-568.
    • (1999) Immunity , vol.10 , pp. 559-568
    • Viret, C.1    Wong, F.S.2    Janeway Jr, C.A.3
  • 9
    • 0037450727 scopus 로고    scopus 로고
    • T cell regulation as a side effect of homeostasis and competition
    • Barthlott, T., Kassiotis, G. and Stockinger, B., T cell regulation as a side effect of homeostasis and competition. J. Exp. Med. 2003. 197: 451-460.
    • (2003) J. Exp. Med , vol.197 , pp. 451-460
    • Barthlott, T.1    Kassiotis, G.2    Stockinger, B.3
  • 10
    • 0035865338 scopus 로고    scopus 로고
    • Autologous regulation of naive T cell homeostasis within the T cell compartment
    • Dummer, W., Ernst, B., LeRoy, E., Lee, D. and Surh, C., Autologous regulation of naive T cell homeostasis within the T cell compartment. J. Immunol. 2001. 166: 2460-2468.
    • (2001) J. Immunol , vol.166 , pp. 2460-2468
    • Dummer, W.1    Ernst, B.2    LeRoy, E.3    Lee, D.4    Surh, C.5
  • 11
    • 0037438341 scopus 로고    scopus 로고
    • Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition
    • Troy, A. E. and Shen, H., Cutting edge: homeostatic proliferation of peripheral T lymphocytes is regulated by clonal competition. J. Immunol. 2003. 170: 672-676.
    • (2003) J. Immunol , vol.170 , pp. 672-676
    • Troy, A.E.1    Shen, H.2
  • 12
    • 25444525391 scopus 로고    scopus 로고
    • The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation
    • Fortner, K. A. and Budd, R. C., The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation. J. Immunol. 2005. 175: 4374-4382.
    • (2005) J. Immunol , vol.175 , pp. 4374-4382
    • Fortner, K.A.1    Budd, R.C.2
  • 13
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath, A. W., Bogatzki, L. Y. and Bevan, M. J., Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 2000. 192: 557-564.
    • (2000) J. Exp. Med , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 14
    • 0025875259 scopus 로고
    • Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L. and Eisenberg, R. A., Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 1991. 9: 243-269.
    • (1991) Annu. Rev. Immunol , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 15
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet, P., Metcalf, D., Huang, D. C., Tarlinton, D. M., Kay, T. W., Kontgen, F., Adams, J. M. and Strasser, A., Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999. 286: 1735-1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5    Kontgen, F.6    Adams, J.M.7    Strasser, A.8
  • 16
    • 0036794390 scopus 로고    scopus 로고
    • Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis
    • Rathmell, J. C., Lindsten, T., Zong, W. X., Cinalli, R. M. and Thompson, C. B., Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nat. Immunol. 2002. 3: 932-939.
    • (2002) Nat. Immunol , vol.3 , pp. 932-939
    • Rathmell, J.C.1    Lindsten, T.2    Zong, W.X.3    Cinalli, R.M.4    Thompson, C.B.5
  • 17
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga, R., Brannan, C. I., Copeland, N. G., Jenkins, N. A. and Nagata, S., Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992. 356: 314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 18
    • 0024209920 scopus 로고
    • Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice
    • Kotzin, B. L., Babcock, S. K. and Herron, L. R., Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice. J. Exp. Med. 1988. 168: 2221-2229.
    • (1988) J. Exp. Med , vol.168 , pp. 2221-2229
    • Kotzin, B.L.1    Babcock, S.K.2    Herron, L.R.3
  • 19
    • 0025214415 scopus 로고
    • Altered expression of self-reactive TCR Vb regions in autoimmune mice
    • Mountz, J. D., Smith, T. M. and Toth, K. S., Altered expression of self-reactive TCR Vb regions in autoimmune mice. J. Immunol. 1990. 144: 2158-2159.
    • (1990) J. Immunol , vol.144 , pp. 2158-2159
    • Mountz, J.D.1    Smith, T.M.2    Toth, K.S.3
  • 20
    • 0024331976 scopus 로고
    • Tolerance-related V b clonal deletions in normal CD4-8-, TCR-ab1 and abnormal lpr and gld cell populations
    • Singer, P. A., Balderas, R. S., McEvilly, R. J., Bobardt, M. and Theofilopoulos, A. N., Tolerance-related V b clonal deletions in normal CD4-8-, TCR-ab1 and abnormal lpr and gld cell populations. J. Exp. Med. 1989. 170: 1869-1877.
    • (1989) J. Exp. Med , vol.170 , pp. 1869-1877
    • Singer, P.A.1    Balderas, R.S.2    McEvilly, R.J.3    Bobardt, M.4    Theofilopoulos, A.N.5
  • 21
    • 0025873567 scopus 로고
    • Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice
    • Zhou, T., Bluethmann, H., Eldridge, J., Brockhaus, M., Berry, K. and Mountz, J. D., Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice. J. Immunol. 1991. 147: 466-474.
    • (1991) J. Immunol , vol.147 , pp. 466-474
    • Zhou, T.1    Bluethmann, H.2    Eldridge, J.3    Brockhaus, M.4    Berry, K.5    Mountz, J.D.6
  • 22
    • 0032482160 scopus 로고    scopus 로고
    • A role for Fas in negative selection of thymocytes in vivo
    • Kishimoto, H., Surh, C. D. and Sprent, J., A role for Fas in negative selection of thymocytes in vivo. J. Exp. Med. 1998. 187: 1427-1438.
    • (1998) J. Exp. Med , vol.187 , pp. 1427-1438
    • Kishimoto, H.1    Surh, C.D.2    Sprent, J.3
  • 23
    • 0026060648 scopus 로고
    • Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus
    • Matsumoto, K., Yoshikai, Y., Asano, T., Himeno, K., Iwasaki, A. and Nomoto, K., Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus. J. Exp. Med. 1994. 173: 127-136.
    • (1994) J. Exp. Med , vol.173 , pp. 127-136
    • Matsumoto, K.1    Yoshikai, Y.2    Asano, T.3    Himeno, K.4    Iwasaki, A.5    Nomoto, K.6
  • 25
    • 38949119408 scopus 로고    scopus 로고
    • Apoptosis regulators Fas and Bim cooperate in the shutdown of chronic immune responses and prevention of autoimmunity
    • Hughes, P. D., Belz, G. T., Fortner, K. A., Budd, R. C., Strasser, A. and Bouillet, P., Apoptosis regulators Fas and Bim cooperate in the shutdown of chronic immune responses and prevention of autoimmunity. Immunity 2008. 28: 1-9.
    • (2008) Immunity , vol.28 , pp. 1-9
    • Hughes, P.D.1    Belz, G.T.2    Fortner, K.A.3    Budd, R.C.4    Strasser, A.5    Bouillet, P.6
  • 26
    • 0028079746 scopus 로고
    • Delayed kinetics of T lymphocyte anergy and deletion in lpr mice
    • Mixter, P. F., Russell, J. Q. and Budd, R. C., Delayed kinetics of T lymphocyte anergy and deletion in lpr mice. J. Autoimmunity 1994. 7: 697-710.
    • (1994) J. Autoimmunity , vol.7 , pp. 697-710
    • Mixter, P.F.1    Russell, J.Q.2    Budd, R.C.3
  • 27
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser, A., Harris, A. W., Huang, D. C., Krammer, P. H. and Cory, S., Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 1995. 14: 6136-6147.
    • (1995) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 28
    • 0028898599 scopus 로고
    • Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
    • Maldonado, M. A., Eisenberg, R. A., Roper, E., Cohen, P. L. and Kotzin, B. L., Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. J. Exp. Med. 1995. 181: 641-648.
    • (1995) J. Exp. Med , vol.181 , pp. 641-648
    • Maldonado, M.A.1    Eisenberg, R.A.2    Roper, E.3    Cohen, P.L.4    Kotzin, B.L.5
  • 29
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi, T., Tanaka, M., Brannan, C. I., Jenkins, N. A., Copeland, N. G., Suda, T. and Nagata, S., Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994. 76: 969-976.
    • (1994) Cell , vol.76 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 30
    • 37549048249 scopus 로고    scopus 로고
    • The BCL-2 protein family: opposing activities that mediate cell death
    • Youle, R. J. and Strasser, A., The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 2008. 9: 47-59.
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , pp. 47-59
    • Youle, R.J.1    Strasser, A.2
  • 33
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner, T., Mogil, R. J., LaFace, D., Yoo, N. J., Mahboubi, A., Echeverri, F., Martin, S. J. et al., Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995. 373: 441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1    Mogil, R.J.2    LaFace, D.3    Yoo, N.J.4    Mahboubi, A.5    Echeverri, F.6    Martin, S.J.7
  • 34
    • 0033549813 scopus 로고    scopus 로고
    • Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization
    • Yu, W., Nagaoka, H., Jankovic, M., Misulovin, Z., Suh, H., Rolink, A., Melchers, F. et al., Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization. Nature 1999. 400: 682-687.
    • (1999) Nature , vol.400 , pp. 682-687
    • Yu, W.1    Nagaoka, H.2    Jankovic, M.3    Misulovin, Z.4    Suh, H.5    Rolink, A.6    Melchers, F.7
  • 35
    • 38949210228 scopus 로고    scopus 로고
    • Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction
    • Weant, A. E., Michalek, R. D., Khan, I. U., Holbrook, B. C., Willingham, M. C. and Grayson, J. M., Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction. Immunity 2008. 28: 218-230.
    • (2008) Immunity , vol.28 , pp. 218-230
    • Weant, A.E.1    Michalek, R.D.2    Khan, I.U.3    Holbrook, B.C.4    Willingham, M.C.5    Grayson, J.M.6
  • 36
    • 0027279683 scopus 로고
    • CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor
    • Landolfi, M. M., Van Houten, N., Russell, J. Q., Scollay, R., Parnes, J. R. and Budd, R. C., CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor. J. Immunol. 1993. 151: 1086-1096.
    • (1993) J. Immunol , vol.151 , pp. 1086-1096
    • Landolfi, M.M.1    Van Houten, N.2    Russell, J.Q.3    Scollay, R.4    Parnes, J.R.5    Budd, R.C.6
  • 37
    • 0028985494 scopus 로고
    • Decreased CD4-CD8- TCR-ab+ cells in lpr/lpr mice lacking beta 2-microglobulin
    • Mixter, P. F., Russell, J. Q., Durie, F. H. and Budd, R. C., Decreased CD4-CD8- TCR-ab+ cells in lpr/lpr mice lacking beta 2-microglobulin. J. Immunol. 1995. 154: 2063-2074.
    • (1995) J. Immunol , vol.154 , pp. 2063-2074
    • Mixter, P.F.1    Russell, J.Q.2    Durie, F.H.3    Budd, R.C.4
  • 39
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatiblity complex class II-deficient MRL-lpr mice
    • Jevnikar, A. M., Grusby, M. J. and Glimcher, L. H., Prevention of nephritis in major histocompatiblity complex class II-deficient MRL-lpr mice. J. Exp. Med. 1994. 179: 1137-1143.
    • (1994) J. Exp. Med , vol.179 , pp. 1137-1143
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 40
    • 38949209522 scopus 로고    scopus 로고
    • Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity
    • Hutcheson, J., Scatizzi, J. C., Siddiqui, A. M., Haines, G. K., III, Wu, T., Li, Q.-Z., Davis, L. S. et al. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity 2008. 28: 208-217.
    • (2008) Immunity , vol.28 , pp. 208-217
    • Hutcheson, J.1    Scatizzi, J.C.2    Siddiqui, A.M.3    Haines III, G.K.4    Wu, T.5    Li, Q.-Z.6    Davis, L.S.7
  • 42
    • 0344198588 scopus 로고    scopus 로고
    • Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
    • Pellegrini, M., Belz, G., Bouillet, P. and Strasser, A., Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc. Natl. Acad. Sci. USA 2003. 100: 14175-14180.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 14175-14180
    • Pellegrini, M.1    Belz, G.2    Bouillet, P.3    Strasser, A.4
  • 43
    • 0035004527 scopus 로고    scopus 로고
    • Cancer and autoimmunity: autoimmune and rheumatic features in patients with malignancies
    • Abu-Shakra, M., Buskila, D., Ehrenfeld, M., Conrad, K. and Shoenfeld, Y., Cancer and autoimmunity: autoimmune and rheumatic features in patients with malignancies. Ann. Rheum. Dis. 2001. 60: 433-441.
    • (2001) Ann. Rheum. Dis , vol.60 , pp. 433-441
    • Abu-Shakra, M.1    Buskila, D.2    Ehrenfeld, M.3    Conrad, K.4    Shoenfeld, Y.5
  • 44
    • 0037089332 scopus 로고    scopus 로고
    • Autoimmunity in human primary immunodeficiency diseases
    • Arkwright, P. D., Abinun, M. and Cant, A. J., Autoimmunity in human primary immunodeficiency diseases. Blood 2001. 99: 2694-2702.
    • (2001) Blood , vol.99 , pp. 2694-2702
    • Arkwright, P.D.1    Abinun, M.2    Cant, A.J.3
  • 45
    • 0033636339 scopus 로고    scopus 로고
    • The changing spectrum of rheumatic disease in human immunodeficiency virus infection
    • Reveille, J. D., The changing spectrum of rheumatic disease in human immunodeficiency virus infection. Semin. Arth. Rheum. 2000. 30: 147-166.
    • (2000) Semin. Arth. Rheum , vol.30 , pp. 147-166
    • Reveille, J.D.1
  • 46
    • 0034914252 scopus 로고    scopus 로고
    • Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis
    • Goronzy, J. J. and Weyand, C. M., Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis. Trends Immunol. 2001. 22: 251-255.
    • (2001) Trends Immunol , vol.22 , pp. 251-255
    • Goronzy, J.J.1    Weyand, C.M.2
  • 48
    • 1942453326 scopus 로고    scopus 로고
    • Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
    • King, C., Ilic, A., Koelsch, K. and Sarvetnick, N., Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 2004. 117: 265-277.
    • (2004) Cell , vol.117 , pp. 265-277
    • King, C.1    Ilic, A.2    Koelsch, K.3    Sarvetnick, N.4
  • 49
    • 0030614415 scopus 로고    scopus 로고
    • Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis
    • Sneller, M. C., Wang, J., Dale, J. K., Strober, W., Middelton, L. A., Choi, Y., Fleisher, T. A. et al., Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis. Blood 1997. 89: 1341-1348.
    • (1997) Blood , vol.89 , pp. 1341-1348
    • Sneller, M.C.1    Wang, J.2    Dale, J.K.3    Strober, W.4    Middelton, L.A.5    Choi, Y.6    Fleisher, T.A.7
  • 50
    • 0345059209 scopus 로고    scopus 로고
    • An inherited disorder of lymphocyte apoptosis: the autoimmune lympho-proliferative syndrome
    • Straus, S. E., Sneller, M., Lenardo, M. J., Puck, J. M. and Strober, W., An inherited disorder of lymphocyte apoptosis: the autoimmune lympho-proliferative syndrome. Ann. Int. Med. 1999. 130: 591-601.
    • (1999) Ann. Int. Med , vol.130 , pp. 591-601
    • Straus, S.E.1    Sneller, M.2    Lenardo, M.J.3    Puck, J.M.4    Strober, W.5
  • 51
    • 0024341842 scopus 로고
    • T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD41 T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis
    • Shivakumar, S., Tsokos, G. C. and Datta, S. K., T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD41 T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis. J. Immunol. 1989. 143: 103-112.
    • (1989) J. Immunol , vol.143 , pp. 103-112
    • Shivakumar, S.1    Tsokos, G.C.2    Datta, S.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.