Pien Tze Huang inhibits tumor cell proliferation and promotes apoptosis via suppressing the STAT3 pathway in a colorectal cancer mouse model

International Journal of Oncology

Volumn 40, Issue 5, 2012, Pages 1569-1574

  Zhuang, Qunchuan ^a   Hong, Fei ^b   Shen, Aling ^a   Zheng, Liangpu ^a   Zeng, Jianwei ^a   Lin, Wei ^a   Chen, Youqin ^c   Sferra, Thomas J ^c   Hong, Zhenfeng ^a   Peng, J U N ^a,b  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Zhangzhou Pien Tze Huang Pharmaceutical Co Ltd   (China)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Chinese medicine; Colorectal cancer; Pien Tze Huang; Proliferation; STAT3 pathway

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; PIEN TZE HUANG; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER MODEL; CANCER SIZE; CELL PROLIFERATION; CHINESE MEDICINE; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; WEIGHT GAIN;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; DRUGS, CHINESE HERBAL; HT29 CELLS; HUMANS; MALE; MICE; MICE, NUDE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860307864     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1326     Document Type: Article

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