Progresses in the pursuit of aldose reductase inhibitors: The structure-based lead optimization step

European Journal of Medicinal Chemistry

Volumn 51, Issue , 2012, Pages 216-226

  Ramunno, Anna ^b   Cosconati, Sandro ^d   Sartini, Stefania ^c   Maglio, Vita ^b   Angiuoli, Sara ^b   La Pietra, Valeria ^a   Di Maro, Salvatore ^a   Giustiniano, Mariateresa ^a   La Motta, Concettina ^c   Da Settimo, Federico ^c   Marinelli, Luciana ^a   Novellino, Ettore ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Aldose reductase; Diabetes; Docking; Enzyme; Inflammation

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; FIDARESTAT; S 12728; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR DOCKING; PROCESS OPTIMIZATION; VIRTUAL REALITY;

ALDEHYDE REDUCTASE; CATALYTIC DOMAIN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; USER-COMPUTER INTERFACE;

EID: 84860307414     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.02.045     Document Type: Article

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