Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis

Oncogene

Volumn 31, Issue 17, 2012, Pages 2237-2246

  Walia, V ^a,f   Yu, Y ^a   Cao, D ^a   Sun, M ^b   McLean, J R ^c   Hollier, B G ^d   Cheng, J ^a   Mani, S A ^e   Rao, K ^a   Premkumar, L ^a   Elble, R C ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^e UNIVERSITY OF TEXAS   (United States)

^f NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

breast; chloride; differentiation; epithelial to mesenchymal transition; hCLCA2; metastasis

Indexed keywords

BIOLOGICAL MARKER; CHLORIDE CHANNEL; CLAUDIN; FIBRONECTIN; METHYLCELLULOSE; PROTEIN HCLCA 2; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; VIRUS RNA;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER PATIENT; CANCER RISK; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL INVASION; CELL MEMBRANE; CELL MIGRATION; CHLORIDE CURRENT; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; HOMEOSTASIS; HUMAN; HUMAN CELL; LENTIVIRINAE; METASTASIS; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; TUMOR GROWTH; UPREGULATION;

BIOLOGICAL MARKERS; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHLORIDE CHANNELS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; NEOPLASM METASTASIS;

EID: 84860304606     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.392     Document Type: Article

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