Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

International Journal of Oncology

Volumn 37, Issue 5, 2010, Pages 1167-1176

  D'Assoro, Antonino B ^a,b   Leontovich, Alexey ^a   Amato, Angela ^a   Ayers Ringler, Jennifer R ^a   Quatraro, Cosima ^a   Hafner, Kari ^a   Jenkins, Robert B ^a   Libra, Massimo ^b   Ingle, James ^a   Stivala, Franca ^b   Galanis, Evanthia ^a   Salisbury, Jeffrey L ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

Author keywords

Breast cancer; Centrosome amplification; Chromosomal instability; Epithelial mysenchymal transition; Invasive gene networks; Tumor cell heterogeneity; Tumor progression

Indexed keywords

PROTEIN P53; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; METASTASIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, NUDE; MICROARRAY ANALYSIS; MICROSCOPY, FLUORESCENCE; NEOPLASM INVASIVENESS; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77957857864     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000768     Document Type: Article

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