Molecular imaging of small animals with fluorescent proteins: From projection to multimodality

Computerized Medical Imaging and Graphics

Volumn 36, Issue 4, 2012, Pages 259-263

  Yang, Xiaoquan ^a,b   Gong, Hui ^a,b   Fu, Jianwei ^a,b   Quan, Guotao ^a,b   Huang, Chuan ^a,b   Luo, Qingming ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Fluorescence molecular tomography; Fluorescence planner imaging; Fluorescent protein; Micro CT; Multimodality imaging

Indexed keywords

ABSORPTION COEFFICIENTS; BIOLOGICAL PROCESS; BIOLOGICAL TISSUES; CELL RESEARCH; FAST IMAGING; FLUORESCENCE MOLECULAR; FLUORESCENCE MOLECULAR TOMOGRAPHY; FLUORESCENT PROTEIN; HIGH THROUGHPUT; IN-VIVO IMAGING; MICRO CT; MULTI-MODALITY; MULTI-MODALITY IMAGING SYSTEMS; MULTIMODALITY IMAGING; NUDE MICE; PROJECTION IMAGE; PROJECTION IMAGING; PROTEIN TRAFFICKING; QUANTITATIVE RESEARCH; REFLECTION MODES; REPORTER-GENE EXPRESSION; SMALL ANIMAL; SMALL ANIMAL IMAGING; THREE-DIMENSIONAL INFORMATION; VISIBLE LIGHT; WHOLE BODY;

ANIMALS; COMPUTERIZED TOMOGRAPHY; FLUORESCENCE; FLUOROPHORES; GENE EXPRESSION; IMAGING SYSTEMS; PROTEINS; THREE DIMENSIONAL; TISSUE; TOMOGRAPHY;

MOLECULAR IMAGING;

RED FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFACT; FLUORESCENCE IMAGING; FLUORESCENCE MOLECULAR TOMOGRAPHY; IMAGE ANALYSIS; IMAGE PROCESSING; IN VIVO STUDY; INTERMETHOD COMPARISON; MALE; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR IMAGING; MOUSE; NONHUMAN; PLANNER IMAGING SYSTEM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; THREE DIMENSIONAL IMAGING; VALIDATION STUDY;

ANIMALS; EQUIPMENT DESIGN; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; LUMINESCENT PROTEINS; MALE; MICE; MICE, NUDE; MOLECULAR IMAGING; MONTE CARLO METHOD; NASOPHARYNGEAL NEOPLASMS; NEOPLASM TRANSPLANTATION; X-RAY INTENSIFYING SCREENS; X-RAY MICROTOMOGRAPHY;

EID: 84860297338     PISSN: 08956111     EISSN: 18790771     Source Type: Journal    
DOI: 10.1016/j.compmedimag.2011.09.002     Document Type: Article

References (35)

1. Kobayashi H., Ogawa M., Alford R., Choyke P.L., Urano Y. New strategies for fluorescent probe design in medical diagnostic imaging. Chem Rev 2010, 110(5):2620-2640.
2. Tsien R.Y. The green fluorescent protein. Annu Rev Biochem 1998, 67:509-544.
3. Tsien R.Y. Constructing and exploiting the fluorescent protein paintbox (nobel lecture). Angew Chem Int Ed 2009, 48(31):5612-5626.
4. Stephens D.J., Allan V.J. Light microscopy techniques for live cell imaging. Science 2003, 300(5616):82-86.
5. Yuste R. Fluorescence microscopy today. Nat Methods 2005, 2(12):902-904.
6. Cahalan M.D., Parker I., Wei S.H., Miller M.J. Two-photon tissue imaging: seeing the immune system in a fresh light. Nat Rev Immunol 2002, 2(11):872-880.
7. Ntziachristos V. Fluorescence molecular imaging. Annu Rev Biomed Eng 2006, 8:1-33.
8. Chu J., Zhang Z.H., Zheng Y., Yang J., Qin L.S., Lu J.L., et al. A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions. Biosens Bioelectron 2009, 25(1):234-239.
9. Shu X.K., Royant A., Lin M.Z., Aguilera T.A., Lev-Ram V., Steinbach P.A., et al. Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome. Science 2009, 324(5928):804-807.
10. Helmchen F., Denk W. Deep tissue two-photon microscopy. Nat Methods 2005, 2(12):932-940.
11. Ntziachristos V., Ripoll J., Wang L.H.V., Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol 2005, 23(3):313-320.
12. Kumar A.T.N., Raymond S.B., Dunn A.K., Bacskai B.J., Boas D.A. A time domain fluorescence tomography system for small animal Imaging. IEEE Trans Med Imaging 2008, 27(8):1152-1163.
13. Eppstein M.J., Hawrysz D.J., Godavarty A., Sevick-Muraca E.M. Three-dimensional, Bayesian image reconstruction from sparse and noisy data sets: near-infrared fluorescence tomography. Proc Natl Acad Sci USA 2002, 99(15):9619-9624.
14. Deliolanis N., Lasser T., Hyde D., Soubret A., Ripoll J., Ntziachristos V. Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett 2007, 32(4):382-384.
15. Ntziachristos V. Going deeper than microscopy: the optical imaging frontier in biology. Nat Methods 2010, 7(8):603-614.
16. Kepshire D., Mincu N., Hutchins M., Gruber J., Dehghani H., Hypnarowski J., et al. A microcomputed tomography guided fluorescence tomography system for small animal molecular imaging. Rev Sci Instrum 2009, 80(4):043701.
17. Davis S.C., Pogue B.W., Springett R., Leussler C., Mazurkewitz P., Tuttle S.B., et al. Magnetic resonance-coupled fluorescence tomography scanner for molecular imaging of tissue. Rev Sci Instrum 2008, 79(6):064302.
18. Razansky D., Ntziachristos V. Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys 2007, 34(11):4293-4301.
19. Holdsworth D.W., Thornton M.M. Micro-CT in small animal and specimen imaging. Trends Biotechnol 2002, 20(8):S34-S39.
20. Schulz R.B., Ale A., Sarantopoulos A., Freyer M., Soehngen E., Zientkowska M., et al. Hybrid system for simultaneous fluorescence and X-ray computed tomography. IEEE Trans Med Imaging 2010, 29(2):465-473.
21. Lin Y.T., Barber W.C., Iwanczyk J.S., Roeck W., Nalcioglu O., Gulsen G. Quantitative fluorescence tomography using a combined tri-modality FT/DOT/XCT system. Opt Express 2010, 18(8):7835-7850.
22. Cao L.J., Peter J. Bayesian reconstruction strategy of fluorescence-mediated tomography using an integrated SPECT-CT-OT system. Phys Med Biol 2010, 55(9):2693-2708.
23. Ntziachristos V., Bremer C., Weissleder R. Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol 2003, 13(1):195-208.
24. Graves E.E., Weissleder R., Ntziachristos V. Fluorescence molecular imaging of small animal tumor models. Curr Mol Med 2004, 4(4):419-430.
25. Ntziachristos V., Turner G., Dunham J., Windsor S., Soubret A., Ripoll J., et al. Planar fluorescence imaging using normalized data. J Biomed Opt 2005, 10(6):064007.
26. Oshiro M., Moomaw B. Cooled vs. intensified vs. electron bombardment CCD cameras - applications and relative advantages. Methods Cell Biol 2003, 72:133-156.
27. Billinton N., Knight A.W. Seeing the wood through the trees: a review of techniques for distinguishing green fluorescent protein from endogenous autofluorescence. Anal Biochem 2001, 291(2):175-197.
28. Tamara T., Dragana J-M., Lidia S., Brad R. Quantitative comparison of the sensitivity of detection of fluorescent and bioluminescent reporters in animal models. Mol Imaging 2004, 3(1):9-23.
29. Yang X.Q., Gong H., Quan G.T., Deng Y., Luo Q.M. Combined system of fluorescence diffuse optical tomography and microcomputed tomography for small animal imaging. Rev Sci Instrum 2010, 81(5):054304.
30. Yang X.Q., Meng Y.Z., Luo Q.M., Gong H. High resolution in vivo micro-CT with flat panel detector based on amorphous silicon. J X-ray Sci Technol 2010.
31. Fu J.W., Yang X.Q., Quan G.T., Gong H. Fluorescence molecular tomography system for in-vivo tumor imaging in small animals. Chin Opt Lett 2010.
32. Schulz R.B., Peter J., Semmler W., D'Andrea C., Valentini G., Cubeddu R. Comparison of noncontact and fiber-based fluorescence-mediated tomography. Opt Lett 2006, 31(6):769-771.
33. Hyde D., Schulz R., Brooks D., Miller E., Ntziachristos V. Performance dependence of hybrid x-ray computed tomography/fluorescence molecular tomography on the optical forward problem. J Opt Soc Am A 2009, 26(4):919-923.
34. Meng Y., Yang X., Deng Y., Zhang X., Gong H. A Method of Extracting Structural Priors from Images of Micro-CT for Fluorescence Molecular Tomography Reconstruction 2011.
35. Quan G.T., Gong H., Deng Y., Fu J.W., Luo Q.M. Monte Carlo-based fluorescence molecular tomography reconstruction method accelerated by a cluster of graphic processing units. J Biomed Opt 2011, 16(2).