-
1
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
Williams G (1957) Pleiotropy, natural selection, and the evolution of senescence. Evolution 11: 398-411.
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.1
-
3
-
-
0031690075
-
The evolution of aging: A new approach to an old problem of biology
-
DOI 10.1016/S0306-9877(98)90079-2
-
Bowles J (1998) The evolution of aging: a new approach to an old problem of biology. Med Hypotheses 51: 179-221. (Pubitemid 28418849)
-
(1998)
Medical Hypotheses
, vol.51
, Issue.3
, pp. 179-221
-
-
Bowles, J.T.1
-
4
-
-
0025117953
-
An attempt at a rational classification of theories of ageing
-
Medvedev Z (1990) An attempt at a rational classification of theories of ageing. Biol Rev Camb Philos Soc 65: 375-398.
-
(1990)
Biol Rev Camb Philos Soc
, vol.65
, pp. 375-398
-
-
Medvedev, Z.1
-
5
-
-
0035945252
-
n repeats
-
Milyavsky M, Mimran A, Senderovich S et al. (2001) Activation of p53 protein by telomeric (TTAGGG) repeats. Nucleic Acids Res 29: 5207-5215. (Pubitemid 34065439)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.24
, pp. 5207-5215
-
-
Milyavsky, M.1
Mimran, A.2
Senderovich, S.3
Zurer, I.4
Erez, N.5
Shats, I.6
Goldfinger, N.7
Cohen, I.8
Rotter, V.9
-
7
-
-
0036139411
-
Modelling telomere shortening and the role of oxidative stress
-
DOI 10.1016/S0047-6374(01)00380-3, PII S0047637401003803
-
Proctor C, Kirkwood T (2002) Modelling telomere shortening and the role of oxidative stress. Mech Ageing Dev 123: 351-363. (Pubitemid 34024923)
-
(2002)
Mechanisms of Ageing and Development
, vol.123
, Issue.4
, pp. 351-363
-
-
Proctor, C.J.1
Kirkwood, T.B.L.2
-
8
-
-
0033808563
-
Nutrition, oxidative damage, telomere shortening, and cellular senescence: Individual or connected agents of ageing?
-
Jennings B, Ozanne S, Hales C (2000) Nutrition, oxidative damage, telomere shortening, and cellular senescence: individual or connected agents of ageing? Mol Gen Metab 71: 32-42.
-
(2000)
Mol Gen Metab
, vol.71
, pp. 32-42
-
-
Jennings, B.1
Ozanne, S.2
Hales, C.3
-
9
-
-
0034832956
-
Regulation of cellular senescence by p53
-
DOI 10.1046/j.1432-1327.2001.02228.x
-
Itahana K, Dimri G, Campisi J (2001) Regulation of cellular senescence by p53. Eur J Biochem 28: 2784-2791. (Pubitemid 32862960)
-
(2001)
European Journal of Biochemistry
, vol.268
, Issue.10
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
10
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
DOI 10.1038/nrm2233, PII NRM2233
-
Campisi J, d'Adda di Fagagna F (2007) Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740. (Pubitemid 47312822)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
11
-
-
0037148271
-
Telomerase in the human organism
-
DOI 10.1038/sj/onc/1205083
-
Collins K, Mitchell J (2002) Telomerase in the human organism. Oncogene 21: 564-579. (Pubitemid 34146256)
-
(2002)
Oncogene
, vol.21
, Issue.4
, pp. 564-579
-
-
Collins, K.1
Mitchell, J.R.2
-
12
-
-
38048999665
-
Two faces of p53: Aging and tumor suppression
-
Rodier F, Campisi J, Bhaumik D (2007) Two faces of p53: aging and tumor suppression. Nucleic Acids Res 35: 7475-7484.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7475-7484
-
-
Rodier, F.1
Campisi, J.2
Bhaumik, D.3
-
13
-
-
18544379476
-
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin
-
DOI 10.1074/jbc.M112401200
-
Han Z, Weil W, Dunaway S et al. (2002) Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin. J Biol Chem 277: 17154-17160. (Pubitemid 34967748)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.19
, pp. 17154-17160
-
-
Han, Z.1
Wei, W.2
Dunaway, S.3
Darnowski, J.W.4
Calabresi, P.5
Sedivy, J.6
Hendrickson, E.A.7
Balan, K.V.8
Pantazis, P.9
Wyche, J.H.10
-
15
-
-
39049091805
-
Telomerase, senescence and ageing
-
Shawi M, Autexier C (2008) Telomerase, senescence and ageing. Mech Ageing Dev 129: 3-10.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 3-10
-
-
Shawi, M.1
Autexier, C.2
-
16
-
-
55449122193
-
Telomerase reverse transcriptase delays aging in cancer-resistant mice
-
Tomas-Loba A, Flores I, Fernandez-Marcos P et al. (2008) Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell 135: 609-622.
-
(2008)
Cell
, vol.135
, pp. 609-622
-
-
Tomas-Loba, A.1
Flores, I.2
Fernandez-Marcos, P.3
-
17
-
-
34247580184
-
Telomeres limit cancer growth by inducing senescence: Long-sought in vivo evidence obtained
-
DOI 10.1016/j.ccr.2007.04.014, PII S1535610807001201
-
Sedivy J (2007) Telomeres limit cancer growth by inducing senescence: long sought in vivo evidence obtained. Cancer Cell 11: 389-391. (Pubitemid 46670082)
-
(2007)
Cancer Cell
, vol.11
, Issue.5
, pp. 389-391
-
-
Sedivy, J.M.1
-
18
-
-
33748857195
-
Evolutionary explanations of the "actuarial senescence in the wild" and of the "state of senility"
-
DOI 10.1100/tsw.2006.209
-
Libertini G (2006) Evolutionary explanations of the 'actuarial senescence in the wild' and of the 'state of senility'. Sci World J 6: 1086-1108. (Pubitemid 44440815)
-
(2006)
TheScientificWorldJournal
, vol.6
, pp. 1086-1108
-
-
Libertini, G.1
-
19
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe J, Patil C, Rodier F et al. (2008) Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 6: 2853-2868.
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppe, J.1
Patil, C.2
Rodier, F.3
-
20
-
-
13944260728
-
Stromal-epithelial interactions in aging and cancer: Senescent fibroblasts alter epithelial cell differentiation
-
DOI 10.1242/jcs.01635
-
Parrinello S, Coppe J, Krtolica A et al. (2005) Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Biol 118: 485-496. (Pubitemid 40310116)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.3
, pp. 485-496
-
-
Parrinello, S.1
Coppe, J.-P.2
Krtolica, A.3
Campisi, J.4
-
21
-
-
38949094875
-
Telomere ResQue and preservation-Roles for the Werner syndrome protein and other RecQ helicases
-
DOI 10.1016/j.mad.2007.10.007, PII S0047637407001686
-
Opresko P (2008) Telomere ResQue and preservation-roles for the Werner syndrome protein and other RecQ helicases. Mech Ageing Dev 129: 79-90. (Pubitemid 351210677)
-
(2008)
Mechanisms of Ageing and Development
, vol.129
, Issue.1-2
, pp. 79-90
-
-
Opresko, P.L.1
-
24
-
-
0345272134
-
Observation and theory
-
Newton-Smith W, ed.,. Malden, MA: Blackwell Publishing Ltd
-
Achinstein P (2000) Observation and theory. In Newton-Smith W, ed., A Companion to the Philosophy of Science. Malden, MA: Blackwell Publishing Ltd, pp. 325-334.
-
(2000)
A Companion to the Philosophy of Science
, pp. 325-334
-
-
Achinstein, P.1
-
25
-
-
0013942563
-
The moulding of senescence by natural selection
-
Hamilton W (1966) The moulding of senescence by natural selection. J Theor Biol 12: 12-45.
-
(1966)
J Theor Biol
, vol.12
, pp. 12-45
-
-
Hamilton, W.1
-
28
-
-
33644998317
-
Aging selected for its own sake
-
Mitteldorf J (2004) Aging selected for its own sake. EER 6: 1-17.
-
(2004)
EER
, vol.6
, pp. 1-17
-
-
Mitteldorf, J.1
-
29
-
-
0038049143
-
Cancer and ageing: Rival demons?
-
DOI 10.1038/nrc1073
-
Campisi J (2003) Cancer and ageing: rival demons? Nat Rev Cancer 3: 339-349. (Pubitemid 37328854)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 339-349
-
-
Campisi, J.1
-
30
-
-
0033976788
-
Replicative senescence as a barrier to human cancer
-
Parkinson E, Munro J, Steeghs K et al. (2000) Replicative senescence as a barrier to human cancer. Biochem Soc Trans 28: 226-233. (Pubitemid 30103247)
-
(2000)
Biochemical Society Transactions
, vol.28
, Issue.2
, pp. 226-233
-
-
Parkinson, E.K.1
Munro, J.2
Steeghs, K.3
Morrison, V.4
Ireland, H.5
Forsyth, N.6
Fitzsimmons, S.7
Bryce, S.8
-
31
-
-
34447543913
-
Cellular senescence in cancer and aging
-
DOI 10.1016/j.cell.2007.07.003, PII S0092867407008902
-
Collado M, Blasco M, Serrano M (2007) Cellular senescence in cancer and aging. Cell 130: 223-233. (Pubitemid 47081143)
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
33
-
-
0032422122
-
Telomerase activity in 'immortal' fish
-
DOI 10.1016/S0014-5793(98)01020-5, PII S0014579398010205
-
Klapper W, Heidorn K, Kuhne K et al. (1998) Telomerase activity in 'immortal' fish. FEBS 434: 409-412. (Pubitemid 29052266)
-
(1998)
FEBS Letters
, vol.434
, Issue.3
, pp. 409-412
-
-
Klapper, W.1
Heidorn, K.2
Kuhne, K.3
Parwaresch, R.4
Krupp, G.5
-
34
-
-
0032515190
-
Longevity of lobsters is linked to ubiquitous telomerase expression
-
DOI 10.1016/S0014-5793(98)01357-X, PII S001457939801357X
-
Klapper W, Kuhne K, Singh K et al. (1998) Longevity of lobsters is linked to ubiquitous telomerase expression. FEBS 439: 143-146. (Pubitemid 28537881)
-
(1998)
FEBS Letters
, vol.439
, Issue.1-2
, pp. 143-146
-
-
Klapper, W.1
Kuhne, K.2
Singh, K.K.3
Heidorn, K.4
Parwaresch, R.5
Krupp, G.6
-
35
-
-
84864569759
-
Empirical evidence for various evolutionary hypotheses on species demonstrating increasing mortality with increasing chronological age in the wild
-
DOI 10.1100/tsw.2008.36
-
Libertini G (2008) Empirical evidence for various evolutionary hypotheses on species demonstrating increasing mortality with increasing chronological age in the wild. Sci World J 8: 183-193. (Pubitemid 351317535)
-
(2008)
TheScientificWorldJournal
, vol.8
, pp. 183-193
-
-
Libertini, G.1
-
36
-
-
34248578816
-
Telomerase activity is maintained throughout the lifespan of long-lived birds
-
DOI 10.1016/j.exger.2007.03.004, PII S0531556507000587
-
Haussmann M, Winkler D, Huntington C et al. (2007) Telomerase activity is maintained throughout the lifespan of long-lived birds. Exp Gerontol 42: 610-618. (Pubitemid 46756106)
-
(2007)
Experimental Gerontology
, vol.42
, Issue.7
, pp. 610-618
-
-
Haussmann, M.F.1
Winkler, D.W.2
Huntington, C.E.3
Nisbet, I.C.T.4
Vleck, C.M.5
-
37
-
-
58149341744
-
Coevolution of telomerase activity and body mass in mammals: From mice to beavers
-
Gorbunova V, Seluanov A (2009) Coevolution of telomerase activity and body mass in mammals: from mice to beavers. Mech Ageing Dev 130: 3-9.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 3-9
-
-
Gorbunova, V.1
Seluanov, A.2
-
39
-
-
2442628362
-
The case for negative senescence
-
DOI 10.1016/j.tpb.2003.12.003, PII S004058090400022X
-
Vaupel J, Baudisch A, Dolling M et al. (2004) The case for negative senescence. Theor Popul Biol 65: 339-351. (Pubitemid 38611003)
-
(2004)
Theoretical Population Biology
, vol.65
, Issue.4
, pp. 339-351
-
-
Vaupel, J.W.1
Baudisch, A.2
Dolling, M.3
Roach, D.A.4
Gampe, J.5
-
40
-
-
13944262937
-
Understanding the odd science of aging
-
DOI 10.1016/j.cell.2005.01.027
-
Kirkwood T (2005) Understanding the odd science of aging. Cell 120: 437-447. (Pubitemid 40269759)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
41
-
-
16244399543
-
Asymmetry and the origins of ageing
-
DOI 10.1016/j.mad.2005.02.001
-
Kirkwood T (2005) Asymmetry and the origins of ageing. Mech Ageing Dev 126: 533-534. (Pubitemid 40461952)
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, Issue.5
, pp. 533-534
-
-
Kirkwood, T.B.L.1
-
42
-
-
50449103977
-
Evolvability and programmed ageing: A reply to de Grey
-
Goldsmith T (2008) Evolvability and programmed ageing: a reply to de Grey. Rejuvenation Res 11: 847-848.
-
(2008)
Rejuvenation Res
, vol.11
, pp. 847-848
-
-
Goldsmith, T.1
-
43
-
-
0035834121
-
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
-
DOI 10.1073/pnas.211053698
-
Krtolica A, Parrinello S, Lockett S et al. (2001) Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98: 12072-12077. (Pubitemid 32959828)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.21
, pp. 12072-12077
-
-
Krtolica, A.1
Parrinello, S.2
Lockett, S.3
Desprez, P.-Y.4
Campisi, J.5
-
46
-
-
0000827676
-
A mini-review of the evolutionary theories of aging
-
Le Bourg E (2001) A mini-review of the evolutionary theories of aging. Is it time to accept them? Demogr Res 4: 1-28.
-
(2001)
Is It Time to Accept Them?. Demogr Res
, vol.4
, pp. 1-28
-
-
Le Bourg, E.1
-
47
-
-
0023930027
-
An adaptive theory of the increasing mortality with increasing chronological age in populations in the wild
-
Libertini G (1988) An adaptive theory of the increasing mortality with increasing chronological age in populations in the wild. J Theor Biol 132: 145-162.
-
(1988)
J Theor Biol
, vol.132
, pp. 145-162
-
-
Libertini, G.1
-
48
-
-
33645788512
-
Chaotic population dynamics and the evolution of ageing
-
Mitteldorf J (2006) Chaotic population dynamics and the evolution of ageing. EER 8: 561-574.
-
(2006)
EER
, vol.8
, pp. 561-574
-
-
Mitteldorf, J.1
-
49
-
-
33745022569
-
Evolvingdispersal andage atdeath
-
DythamC, Travis J (2006) Evolvingdispersal andage atdeath. Oikos 113: 530-538.
-
(2006)
Oikos
, vol.113
, pp. 530-538
-
-
Dytham, C.1
Travis, J.2
|