Synthesis of three branched iminosugars [(3R,4R,5S)-3-(hydroxymethyl) piperidine-3,4,5-triol, (3R,4R,5R)-3-(hydroxymethyl)piperidine-3,4,5-triol and (3S,4R,5R)-3-(hydroxymethyl)piperidine-3,4,5-triol] and a branched trihydroxynipecotic acid [(3R,4R,5R)-3,4,5-trihydroxypiperidine-3-carboxylic acid] from sugar lactones with a carbon substituent at C-2

Tetrahedron Asymmetry

Volumn 23, Issue 5, 2012, Pages 401-408

  Simone, Michela I ^a,b   Soengas, Raquel G ^b,c   Jenkinson, Sarah F ^b,d   Evinson, Emma L ^e   Nash, Robert J ^e   Fleet, George W J ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF AVEIRO   (Portugal)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e Phytoquest Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (HYDROXYMETHYL)PIPERIDINE 3,4,5 TRIOL; 3,4,5 TRIHYDROXYPIPERIDINE 3 CARBOXYLIC ACID; ALPHA GLUCOSIDASE INHIBITOR; ARABINITOL; IMINOSUGAR; LACTONE; NIPECOTIC ACID DERIVATIVE; RIBOSE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE SYNTHESIS; CHIRALITY; DRUG SPECIFICITY; DRUG SYNTHESIS; ENZYME INHIBITION; GEOBACILLUS STEAROTHERMOPHILUS; IC 50; ISOMER; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL;

EID: 84860278644     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2012.03.007     Document Type: Article

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