Structure-based analysis of the molecular recognitions between HIV-1 TAR-RNA and transcription factor nuclear Factor-kappaB (NFkB)

Current Topics in Medicinal Chemistry

Volumn 12, Issue 8, 2012, Pages 814-827

  Khan, Mahmud Tareq Hassan ^a,b   Mischiati, Carlo ^a   Ather, Arjumand ^a   Ohyama, Tatsuya ^c   Dedachi, Kenichi ^c   Borgatti, Monica ^a   Kurita, Noriyuki ^c   Gambari, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

AIDS; Docking; Fourier transformation; Fragment molecular orbital; HIV 1; Molecular mechanics; Molecular modeling; NF kB; Protein protein interactions; TAR RNA; Transcription factors

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; STAT1 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1A; TAR RNA; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR IID; TRANSCRIPTION FACTOR MBP1; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP1F2; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; BINDING AFFINITY; BIOSENSOR; COMPLEX FORMATION; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; MACROMOLECULE; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN DNA BINDING; PROTEIN RNA BINDING; SURFACE PLASMON RESONANCE; TRANSCRIPTION INITIATION; VIROGENESIS;

HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; MODELS, MOLECULAR; NF-KAPPA B; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RNA, VIRAL;

EID: 84860273553     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612800166800     Document Type: Article

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