메뉴 건너뛰기




Volumn 17, Issue 4, 2012, Pages 3844-3857

Baicalin induces apoptosis in SW620 human colorectal carcinoma cells in Vitro and suppresses tumor growth in Vivo

Author keywords

Apoptosis; Cancer; SW620

Indexed keywords

ANTINEOPLASTIC AGENT; BAICALIN; CASPASE; FLAVONOID; REACTIVE OXYGEN METABOLITE;

EID: 84860251526     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17043844     Document Type: Article
Times cited : (62)

References (39)
  • 1
    • 81155127332 scopus 로고    scopus 로고
    • Alterations of microRNAs contribute to colon carcinogenesis
    • Schetter, A.J.; Harris, C.C. Alterations of microRNAs contribute to colon carcinogenesis. Semin. Oncol. 2011, 38, 734-742.
    • (2011) Semin. Oncol. , vol.38 , pp. 734-742
    • Schetter, A.J.1    Harris, C.C.2
  • 3
    • 68149083139 scopus 로고    scopus 로고
    • Pattern of use of adjuvant chemotherapy for stage II colon cancer: A single-institution experience
    • Osarogiagbon, R.U.; Sachdev, J.C.; Khattak, A.G.; Kronish, L.E. Pattern of use of adjuvant chemotherapy for stage II colon cancer: A single-institution experience. Clin. Colorectal. Cancer 2009, 8, 94-99.
    • (2009) Clin. Colorectal. Cancer , vol.8 , pp. 94-99
    • Osarogiagbon, R.U.1    Sachdev, J.C.2    Khattak, A.G.3    Kronish, L.E.4
  • 5
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton, E., Jr.; Kandaswami, C.; Theoharides, T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 2000, 52, 673-751.
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton Jr., E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 6
    • 18844437520 scopus 로고    scopus 로고
    • Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma
    • Bonham, M.; Posakony, J.; Coleman, I.; Montgomery, B.; Simon, J.; Nelson, P.S. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin. Cancer Res. 2005, 11, 3905-3914.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3905-3914
    • Bonham, M.1    Posakony, J.2    Coleman, I.3    Montgomery, B.4    Simon, J.5    Nelson, P.S.6
  • 7
    • 0034727789 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin
    • Chan, F.L.; Choi, H.L.; Chen, Z.Y.; Chan, P.S.; Huang, Y. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Cancer Lett. 2000, 160, 219-228.
    • (2000) Cancer Lett. , vol.160 , pp. 219-228
    • Chan, F.L.1    Choi, H.L.2    Chen, Z.Y.3    Chan, P.S.4    Huang, Y.5
  • 8
    • 33645068853 scopus 로고    scopus 로고
    • Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines
    • Shieh, D.E.; Cheng, H.Y.; Yen, M.H.; Chiang, L.C.; Lin, C.C. Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines. Am. J. Chin. Med. 2006, 34, 245-261.
    • (2006) Am. J. Chin. Med. , vol.34 , pp. 245-261
    • Shieh, D.E.1    Cheng, H.Y.2    Yen, M.H.3    Chiang, L.C.4    Lin, C.C.5
  • 9
    • 0036181487 scopus 로고    scopus 로고
    • Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines
    • Chang, W.H.; Chen, C.H.; Lu, F.J. Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. Planta Med. 2002, 68, 128-132.
    • (2002) Planta Med. , vol.68 , pp. 128-132
    • Chang, W.H.1    Chen, C.H.2    Lu, F.J.3
  • 10
    • 58749114381 scopus 로고    scopus 로고
    • New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin
    • Li-Weber, M. New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treat. Rev. 2009, 35, 57-68.
    • (2009) Cancer Treat. Rev. , vol.35 , pp. 57-68
    • Li-Weber, M.1
  • 11
    • 79955591914 scopus 로고
    • Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
    • Indran, I.R.; Tufo, G.; Pervaiz, S.; Brenner, C. Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochim. Biophys. Acta 2011, 1807, 735-745.
    • (1807) Biochim. Biophys. Acta , vol.2011 , pp. 735-745
    • Indran, I.R.1    Tufo, G.2    Pervaiz, S.3    Brenner, C.4
  • 12
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti, I.; Migliorati, G.; Pagliacci, M.C.; Grignani, F.; Riccardi, C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 1991, 139, 271-279.
    • (1991) J. Immunol. Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 13
    • 0036931366 scopus 로고    scopus 로고
    • Caspases: Keys in the ignition of cell death
    • Denault, J.B.; Salvesen, G.S. Caspases: Keys in the ignition of cell death. Chem. Rev. 2002, 102, 4489-4500.
    • (2002) Chem. Rev. , vol.102 , pp. 4489-4500
    • Denault, J.B.1    Salvesen, G.S.2
  • 14
    • 0031423791 scopus 로고    scopus 로고
    • Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species
    • Crow, J.P. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1997, 1, 145-157.
    • (1997) Nitric Oxide , vol.1 , pp. 145-157
    • Crow, J.P.1
  • 15
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2', 7'-dichlorofluorescin
    • Rothe, G.; Valet, G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2', 7'-dichlorofluorescin. J. Leukoc. Biol. 1990, 47, 440-448.
    • (1990) J. Leukoc. Biol. , vol.47 , pp. 440-448
    • Rothe, G.1    Valet, G.2
  • 16
    • 34250375517 scopus 로고    scopus 로고
    • Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2
    • Schepelmann, S.; Ogilvie, L.M.; Hedley, D.; Friedlos, F.; Martin, J.; Scanlon, I.; Chen, P.; Marais, R.; Springer, C.J. Suicide gene therapy of human colon carcinoma xenografts using an armed oncolytic adenovirus expressing carboxypeptidase G2. Cancer Res. 2007, 67, 4949-4955.
    • (2007) Cancer Res. , vol.67 , pp. 4949-4955
    • Schepelmann, S.1    Ogilvie, L.M.2    Hedley, D.3    Friedlos, F.4    Martin, J.5    Scanlon, I.6    Chen, P.7    Marais, R.8    Springer, C.J.9
  • 17
    • 79551639050 scopus 로고    scopus 로고
    • Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
    • Wilken, R.; Veena, M.S.; Wang, M.B.; Srivatsan, E.S. Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol. Cancer 2011, 10, 12.
    • (2011) Mol. Cancer , vol.10 , pp. 12
    • Wilken, R.1    Veena, M.S.2    Wang, M.B.3    Srivatsan, E.S.4
  • 18
    • 79953171483 scopus 로고    scopus 로고
    • Carnosol: A promising anti-cancer and anti-inflammatory agent
    • Johnson, J.J. Carnosol: A promising anti-cancer and anti-inflammatory agent. Cancer Lett. 2011, 305, 1-7.
    • (2011) Cancer Lett. , vol.305 , pp. 1-7
    • Johnson, J.J.1
  • 19
    • 0033831080 scopus 로고    scopus 로고
    • A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
    • Khuri, F.R.; Nemunaitis, J.; Ganly, I.; Arseneau, J.; Tannock, I.F.; Romel, L.; Gore, M.; Ironside, J.; MacDougall, R.H.; Heise, C.; et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat. Med. 2000, 6, 879-885.
    • (2000) Nat. Med. , vol.6 , pp. 879-885
    • Khuri, F.R.1    Nemunaitis, J.2    Ganly, I.3    Arseneau, J.4    Tannock, I.F.5    Romel, L.6    Gore, M.7    Ironside, J.8    MacDougall, R.H.9    Heise, C.10
  • 20
    • 0037248328 scopus 로고    scopus 로고
    • Cancer prevention-The potential for diet to modulate molecular signalling
    • Manson, M.M. Cancer prevention-The potential for diet to modulate molecular signalling. Trends Mol. Med. 2003, 9, 11-18.
    • (2003) Trends Mol. Med. , vol.9 , pp. 11-18
    • Manson, M.M.1
  • 21
    • 80855135589 scopus 로고    scopus 로고
    • Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways
    • Zhang, Z.; Teruya, K.; Eto, H.; Shirahata, S. Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways. PLoS One 2011, 6, e27441.
    • (2011) PLoS One , vol.6
    • Zhang, Z.1    Teruya, K.2    Eto, H.3    Shirahata, S.4
  • 22
    • 81155132565 scopus 로고    scopus 로고
    • Arsenic-induced alteration in intracellular calcium homeostasis induces head kidney macrophage apoptosis involving the activation of calpain-2 and ERK in Clarias batrachus
    • Banerjee, C.; Goswami, R.; Datta, S.; Rajagopal, R.; Mazumder, S. Arsenic-induced alteration in intracellular calcium homeostasis induces head kidney macrophage apoptosis involving the activation of calpain-2 and ERK in Clarias batrachus. Toxicol. Appl. Pharmacol. 2011, 256, 44-51.
    • (2011) Toxicol. Appl. Pharmacol. , vol.256 , pp. 44-51
    • Banerjee, C.1    Goswami, R.2    Datta, S.3    Rajagopal, R.4    Mazumder, S.5
  • 24
    • 84863107853 scopus 로고    scopus 로고
    • Indirubin-3-monoxime exhibits anti-inflammatory properties by down-regulating NF-kappaB and JNK signaling pathways in lipopolysaccharide- treated RAW264.7 cells
    • Kim, J.K.; Park, G.M. Indirubin-3-monoxime exhibits anti-inflammatory properties by down-regulating NF-kappaB and JNK signaling pathways in lipopolysaccharide-treated RAW264.7 cells. Inflamm. Res. 2011, 61, 319-325.
    • (2011) Inflamm. Res. , vol.61 , pp. 319-325
    • Kim, J.K.1    Park, G.M.2
  • 25
    • 84856091690 scopus 로고    scopus 로고
    • Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-kappaB signaling pathways
    • Qi, S.; Xin, Y.; Guo, Y.; Diao, Y.; Kou, X.; Luo, L.; Yin, Z. Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-kappaB signaling pathways. Int. Immunopharmacol. 2012, 12, 278-287.
    • (2012) Int. Immunopharmacol. , vol.12 , pp. 278-287
    • Qi, S.1    Xin, Y.2    Guo, Y.3    Diao, Y.4    Kou, X.5    Luo, L.6    Yin, Z.7
  • 27
    • 0032442096 scopus 로고    scopus 로고
    • The proto-oncogene c-myc and apoptosis
    • Hoffman, B.; Liebermann, D.A. The proto-oncogene c-myc and apoptosis. Oncogene 1998, 17, 3351-3357.
    • (1998) Oncogene , vol.17 , pp. 3351-3357
    • Hoffman, B.1    Liebermann, D.A.2
  • 30
    • 2342649469 scopus 로고    scopus 로고
    • Phyto-oestrogens their mechanism of action: Current evidence for a role in breast and prostate cancer
    • Magee, P.J.; Rowland, I.R. Phyto-oestrogens, their mechanism of action: Current evidence for a role in breast and prostate cancer. Br. J. Nutr. 2004, 91, 513-531.
    • (2004) Br. J. Nutr. , vol.91 , pp. 513-531
    • Magee, P.J.1    Rowland, I.R.2
  • 31
    • 0242496947 scopus 로고    scopus 로고
    • Soy isoflavones and cancer prevention
    • Sarkar, F.H.; Li, Y. Soy isoflavones and cancer prevention. Cancer Invest. 2003, 21, 744-757.
    • (2003) Cancer Invest. , vol.21 , pp. 744-757
    • Sarkar, F.H.1    Li, Y.2
  • 32
    • 42649110670 scopus 로고    scopus 로고
    • Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
    • Shukla, S.; Gupta, S. Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation. Free Radic. Biol. Med. 2008, 44, 1833-1845.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1833-1845
    • Shukla, S.1    Gupta, S.2
  • 33
    • 80055008824 scopus 로고    scopus 로고
    • Soybean isoflavone genistein regulates apoptosis through NF-kappaB dependent and independent pathways
    • in press
    • Lee, Y.K.; Park, O.J. Soybean isoflavone genistein regulates apoptosis through NF-kappaB dependent and independent pathways. Exp. Toxicol. Pathol. 2011, in press.
    • (2011) Exp. Toxicol. Pathol.
    • Lee, Y.K.1    Park, O.J.2
  • 34
    • 34247512973 scopus 로고    scopus 로고
    • A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells
    • Ju, W.; Wang, X.; Shi, H.; Chen, W.; Belinsky, S.A.; Lin, Y. A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. Mol. Pharmacol. 2007, 71, 1381-1388.
    • (2007) Mol. Pharmacol. , vol.71 , pp. 1381-1388
    • Ju, W.1    Wang, X.2    Shi, H.3    Chen, W.4    Belinsky, S.A.5    Lin, Y.6
  • 35
    • 33747188963 scopus 로고    scopus 로고
    • Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells
    • Vargo, M.A.; Voss, O.H.; Poustka, F.; Cardounel, A.J.; Grotewold, E.; Doseff, A.I. Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells. Biochem. Pharmacol. 2006, 72, 681-692.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 681-692
    • Vargo, M.A.1    Voss, O.H.2    Poustka, F.3    Cardounel, A.J.4    Grotewold, E.5    Doseff, A.I.6
  • 36
    • 3242766866 scopus 로고    scopus 로고
    • Genistein induces Ca2+ -mediated, calpain/caspase-12-dependent apoptosis in breast cancer cells
    • Sergeev, I.N. Genistein induces Ca2+ -mediated, calpain/caspase-12- dependent apoptosis in breast cancer cells. Biochem. Biophys. Res. Commun. 2004, 321, 462-467.
    • (2004) Biochem. Biophys. Res. Commun. , vol.321 , pp. 462-467
    • Sergeev, I.N.1
  • 37
    • 17844361910 scopus 로고    scopus 로고
    • Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro
    • van Erk, M.J.; Roepman, P.; van der Lende, T.R.; Stierum, R.H.; Aarts, J.M.; van Bladeren, P.J.; van Ommen, B. Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro. Eur. J. Nutr. 2005, 44, 143-156.
    • (2005) Eur. J. Nutr. , vol.44 , pp. 143-156
    • Van Erk, M.J.1    Roepman, P.2    Van Der Lende, T.R.3    Stierum, R.H.4    Aarts, J.M.5    Van Bladeren, P.J.6    Van Ommen, B.7
  • 38
    • 0032856994 scopus 로고    scopus 로고
    • Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells
    • Wang, I.K.; Lin-Shiau, S.Y.; Lin, J.K. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur. J. Cancer 1999, 35, 1517-1525.
    • (1999) Eur. J. Cancer , vol.35 , pp. 1517-1525
    • Wang, I.K.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 39
    • 84862309686 scopus 로고    scopus 로고
    • Flavonoids a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities
    • doi:10.1007/s10555-012-9347-y
    • Weng, C.J.; Yen, G.C. Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. Cancer Metastasis Rev. 2012, doi:10.1007/s10555-012-9347-y.
    • (2012) Cancer Metastasis Rev.
    • Weng, C.J.1    Yen, G.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.