Baicalin-induced apoptosis is mediated by Bcl-2-dependent, but not p53-dependent, pathway in human leukemia cell lines

American Journal of Chinese Medicine

Volumn 34, Issue 2, 2006, Pages 245-261

  Shieh, Den En ^a   Cheng, Hua Yew ^b   Yen, Ming Hong ^c   Chiang, Lien Chai ^d   Lin, Chun Ching ^c  

^a TAJEN INSTITUTE OF TECHNOLOGY   (Taiwan)

^b TUNG FANG INSTITUTE OF TECHNOLOGY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Baicalin; Bcl 2; Caspase 3; Cytochrome c; T ALL

Indexed keywords

ANTINEOPLASTIC AGENT; BAICALEIN; BAICALIN; CASPASE 3; CELL DNA; CYTOCHROME C; DNA FRAGMENT; FAS ANTIGEN; FLUOROURACIL; PROTEIN BCL 2; PROTEIN P53; SCUTELLARIA BAICALENSIS EXTRACT; WOGONIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL ASSAY; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN EXPRESSION; SCUTELLARIA BAICALENSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

APOPTOSIS; CASPASE 3; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CYTOCHROMES C; DNA; FLAVONOIDS; FLOW CYTOMETRY; HUMANS; LEUKEMIA; MEMBRANE POTENTIALS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33645068853     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X06003801     Document Type: Article

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