Gene-selective histone H3 acetylation in the absence of increase in global histone acetylation in liver of rats chronically fed alcohol

Alcohol and Alcoholism

Volumn 47, Issue 3, 2012, Pages 233-239

  Park, Pil Hoon ^a   Lim, Robert W ^b   Shukla, Shivendra D ^b  

^a Yeungnam University   (South Korea)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL DEHYDROGENASE; HISTONE H3; LYSINE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PROTEIN BAX; PROTEIN C JUN; PROTEIN P21; SCATTER FACTOR; SCATTER FACTOR RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FATTY LIVER; GENETIC CODE; HISTONE ACETYLATION; LIVER FUNCTION; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACETYLATION; ALCOHOL DEHYDROGENASE; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GENE EXPRESSION; GENES, JUN; HEPATOCYTE GROWTH FACTOR; HISTONES; LIVER; LYSINE; MALE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

RATTUS;

EID: 84860239988     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/ags004     Document Type: Article

References (35)

1. Allfrey VG, Faulkner R, Mirsky AE. (1964) Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc Natl Acad Sci USA 51:786-94.
2. Badger TM, Hoog JO, Svensson S et al. (2000) Cyclic expression of class I alcohol dehydrogenase in male rats treated with ethanol. Biochem Biophys Res Commun 274:684-8.
3. Bardag-Gorce F, French BA, Joyce M et al. (2007) Histone acetyltransferase p300 modulates gene expression in an epigenetic manner at high blood alcohol levels. Exp Mol Pathol 82:197-202.
4. Bardag-Gorce F, Oliva J, Dedes J et al. (2009) Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding. Alcohol Clin Exp Res 33:684-92.
5. Bosron WF, Magnes LJ, Li TK. (1983) Kinetic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase. Biochemistry 22:1852-7.
6. Buris L, Csabai G, Fodor M et al. (1985) Increase of alcohol dehydrogenase and protein content of liver following chronic ethanol administration. FEBS Lett 183:143-4.
7. Choudhury M, Pandey RS, Clemens DL et al. (2011) Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells. Alcohol 45:311-24.
8. De Carli LM, Lieber CS. (1967) Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid diet. J Nutr 91:331-6.
9. Deaciuc IV, Doherty DE, Burikhanov R et al. (2004) Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion. J Hepatol 40:219-27.
10. Ghosh AK, Varga J. (2007) The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. J Cell Physiol 213:663-71.
11. Gong P, Cederbaum AI, Nieto N. (2003) Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. J Biol Chem 278:29693-700.
12. Grunstein M. (1997) Histone acetylation in chromatin structure and transcription. Nature 389:349-52.
13. He L, Ronis MJ, Badger TM. (2002) Ethanol induction of class I alcohol dehydrogenase expression in the rat occurs through alterations in CCAAT/enhancer binding proteins beta and gamma. J Biol Chem 277:43572-7.
14. He L, Simmen FA, Ronis MJ et al. (2004) Post-translational regulation of sterol regulatory element-binding protein-1 by ethanol induces class I alcohol dehydrogenase in rat liver. J Biol Chem 279:28113-21.
15. Ho YF, Guenthner TM. (1997) Isolation of liver nuclei that retain functional trans-membrane transport. J Pharmacol Toxicol Methods 38:163-8.
16. Jayani RS, Ramanujam PL, Galande S. (2010) Studying histone modifications and their genomic functions by employing chromatin immunoprecipitation and immunoblotting. Methods Cell Biol 98:35-56.
17. Kendrick SF, O'Boyle G, Mann J et al. (2010) Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis. Hepatology 51:1988-97.
18. Koteish A, Yang S, Lin H et al. (2002) Ethanol induces redoxsensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. Alcohol Clin Exp Res 26:1710-8.
19. Lalani el N, Poulsom R, Stamp G et al. (2005) Expression of hepatocyte growth factor and its receptor c-met, correlates with severity of pathological injury in experimental alcoholic liver disease. Int J Mol Med 15:811-7.
20. Lieber CS, Leo MA, Wang X et al. (2008) Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1alpha in rats. Biochem Biophys Res Commun 370:44-8.
21. Marks PA, Richon VM, Breslow R et al. (2001) Histone deacetylase inhibitors as new cancer drugs. Curr Opin Oncol 13:477-83.
22. Mistilis SP, Birchall A. (1969) Induction of alcohol dehydrogenase in the rat. Nature 223:199-200.
23. Park PH, Miller R, Shukla SD. (2003) Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. Biochem Biophys Res Commun 306:501-4.
24. Park PH, Lim RW, Shukla SD. (2005) Involvement of histone acetyltransferase. (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression. Am J Physiol Gastrointest Liver Physiol 289:G1124-36.
25. Rashid A, Wu TC, Huang CC et al. (1999) Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. Hepatology 29:1131-8.
26. Sambucetti LC, Fischer DD, Zabludoff S et al. (1999) Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J Biol Chem 274:34940-7.
27. Shukla SD, Velazquez J, French SW et al. (2008) Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res 32:1525-34.
28. Spitzer JA, Zheng M, Kolls JK et al. (2002) Ethanol and LPS modulate NF-kappaB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo. Front Biosci 7: a99-108.
29. Strahl BD, Allis CD. (2000) The language of covalent histone modifications. Nature 403:41-5.
30. Tadic SD, Elm MS, Li HS et al. (2002) Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury. J Appl Physiol 93:1057-68.
31. Thiagalingam S, Cheng KH, Lee HJ et al. (2003) Histone deacetylases: unique players in shaping the epigenetic histone code. Ann N Y Acad Sci 983:84-100.
32. Villagra A, Sotomayor EM, Seto E. (2010) Histone deacetylases and the immunological network: implications in cancer and inflammation. Oncogene 29:157-73.
33. Wang XD, Liu C, Chung J et al. (1998) Chronic alcohol intake reduces retinoic acid concentration and enhances AP-1. (c-Jun and c-Fos) expression in rat liver. Hepatology 28:744-50.
34. Yuan GJ, Zhou XR, Gong ZJ et al. (2006) Expression and activity of inducible nitric oxide synthase and endothelial nitric oxide synthase correlate with ethanol-induced liver injury. World J Gastroenterol 12:2375-81.
35. Zhou Z, Sun X, Kang YJ. (2001) Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway. Am J Pathol 159:329-38.