Prostaglandin E 2 modulates IL-8 expression through formation of a multiprotein enhanceosome in human colonic epithelial cells

European Journal of Immunology

Volumn 42, Issue 4, 2012, Pages 912-923

  Srivastava, Vikas ^a   Dey, Indranil ^a   Leung, Pearl ^a   Chadee, Kris ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

CREB; Gene regulation; ICER; Inflammation; Promoter

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ENHANCEOSOME; INDUCIBLE CAMP EARLY REPRESSOR; INTERLEUKIN 8; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; CREB1 PROTEIN, HUMAN; CREM PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; IL8 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; PTGER2 PROTEIN, HUMAN;

ARTICLE; CELL ACTIVATION; COLON MUCOSA; COMPLEX FORMATION; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY MECHANISM; TRANSACTIVATION; TRANSCRIPTION INITIATION; BIOSYNTHESIS; CELL STRAIN CACO 2; COLON; CYTOLOGY; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; SIGNAL TRANSDUCTION;

CACO-2 CELLS; COLON; CYCLIC AMP RESPONSE ELEMENT MODULATOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; INTESTINAL MUCOSA; MULTIPROTEIN COMPLEXES; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION;

EID: 84860226953     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141965     Document Type: Article

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