메뉴 건너뛰기




Volumn 26, Issue 4, 2012, Pages 532-542

Modulation of anxiety behavior in the elevated plus maze using peptidic oxytocin and vasopressin receptor ligands in the rat

Author keywords

Anxiolytic; atosiban; carbetocin; desmopressin; diazepam; elevated plus maze; oxytocin; Sprague Dawley rat; vasopressin

Indexed keywords

ANGIOTENSIN II; ARGIPRESSIN; ARGIPRESSIN RECEPTOR; ATOSIBAN; CARBETOCIN; DESMOPRESSIN; DIAZEPAM; DUROTOCIN; LIGAND; NEUROPEPTIDE; OXYTOCIN; OXYTOCIN RECEPTOR; PAMLIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VASOPRESSIN RECEPTOR;

EID: 84860188488     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881111416687     Document Type: Article
Times cited : (71)

References (64)
  • 1
    • 2442424143 scopus 로고    scopus 로고
    • Anxiety and stress fresponses in female oxytocin deficient mice
    • Amico JA, Mantella RC, Vollmer RR, et al. Anxiety and stress fresponses in female oxytocin deficient mice. J Neuroendocrinol. 2004 ; 16: 319-324
    • (2004) J Neuroendocrinol , vol.16 , pp. 319-324
    • Amico, J.A.1    Mantella, R.C.2    Vollmer, R.R.3
  • 2
    • 0023607333 scopus 로고
    • Oxytocin acts as an antidepressant in two animal models of depression
    • Arletti R, Bertolini A. Oxytocin acts as an antidepressant in two animal models of depression. Life Sci. 1987 ; 41: 1725-1730
    • (1987) Life Sci , vol.41 , pp. 1725-1730
    • Arletti, R.1    Bertolini, A.2
  • 3
    • 0029094404 scopus 로고
    • Aged rats are still responsive to the antidepressant and memory-improving effects of oxytocin
    • Arletti R, Benelli A, Poggioli R, et al. Aged rats are still responsive to the antidepressant and memory-improving effects of oxytocin. Neuropeptides. 1995 ; 29: 177-182
    • (1995) Neuropeptides , vol.29 , pp. 177-182
    • Arletti, R.1    Benelli, A.2    Poggioli, R.3
  • 4
    • 0035313575 scopus 로고    scopus 로고
    • CNS region-specific oxytocin receptor expression: Importance in regulation of anxiety and sex behavior
    • Bale TL, Davis AM, Auger AP, et al. CNS region-specific oxytocin receptor expression: importance in regulation of anxiety and sex behavior. J Neurosci. 2001 ; 21: 2546-2552
    • (2001) J Neurosci , vol.21 , pp. 2546-2552
    • Bale, T.L.1    Davis, A.M.2    Auger, A.P.3
  • 5
    • 84860186244 scopus 로고    scopus 로고
    • Oxytocin as a mediator of the unique interoceptive effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in the rat
    • Beringer K, Broadbear JH. Oxytocin as a mediator of the unique interoceptive effects of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") in the rat. Aust Psychol Soc Conf Proc. 2008 ; 43: 31-35
    • (2008) Aust Psychol Soc Conf Proc , vol.43 , pp. 31-35
    • Beringer, K.1    Broadbear, J.H.2
  • 6
    • 0031686222 scopus 로고    scopus 로고
    • Anxiogenic activity in intraventricularly administered arginine vasopressin in the rat
    • Bhattacharya SK, Bhttacharya A, Chakrabarti A. Anxiogenic activity in intraventricularly administered arginine vasopressin in the rat. Biogenic Amines. 1998 ; 14: 367-385
    • (1998) Biogenic Amines , vol.14 , pp. 367-385
    • Bhattacharya, S.K.1    Bhttacharya, A.2    Chakrabarti, A.3
  • 7
    • 1642399711 scopus 로고    scopus 로고
    • Profound impairment in social recognition and reduction in anxiety-like behaviour in vasopressin V1a receptor knockout mice
    • Bielsky IF, Hu SB, Szegda KL, Westphal H, Young LJ. Profound impairment in social recognition and reduction in anxiety-like behaviour in vasopressin V1a receptor knockout mice. Neuropsychopharmacology. 2004 ; 29: 483-493
    • (2004) Neuropsychopharmacology , vol.29 , pp. 483-493
    • Bielsky, I.F.1    Hu, S.B.2    Szegda, K.L.3    Westphal, H.4    Young, L.J.5
  • 8
    • 59849111655 scopus 로고    scopus 로고
    • Characterisation of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior
    • Bleickardt CJ, Mullins DE, MacSweeney CP, et al. Characterisation of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior. Psychopharmacology. 2009 ; 202: 711-718
    • (2009) Psychopharmacology , vol.202 , pp. 711-718
    • Bleickardt, C.J.1    Mullins, D.E.2    MacSweeney, C.P.3
  • 9
    • 42049121951 scopus 로고    scopus 로고
    • Oxytocin reduces anxiety via ERK1/2 activation: Local effect within the rat hypothalamic paraventricular nucleus
    • Blume A, Bosch OJ, Miklos S, Torner L, Wales L, Waldherr M, Neumann ID. Oxytocin reduces anxiety via ERK1/2 activation: local effect within the rat hypothalamic paraventricular nucleus. Eur J Neurosci. 2008 ; 27: 1947-1956
    • (2008) Eur J Neurosci , vol.27 , pp. 1947-1956
    • Blume, A.1    Bosch, O.J.2    Miklos, S.3    Torner, L.4    Wales, L.5    Waldherr, M.6    Neumann, I.D.7
  • 10
    • 79952514962 scopus 로고    scopus 로고
    • Examining the role of oxytocin in the interoceptive effects of 3,4-methylenedioxy-methamphetamine (MDMA, "ecstasy") using a drug discrimination paradigm in the rat
    • Broadbear JH, Tunstall B, Beringer K. Examining the role of oxytocin in the interoceptive effects of 3,4-methylenedioxy-methamphetamine (MDMA, "ecstasy") using a drug discrimination paradigm in the rat. Addiction Biol. 2011 ; 16: 202-214
    • (2011) Addiction Biol , vol.16 , pp. 202-214
    • Broadbear, J.H.1    Tunstall, B.2    Beringer, K.3
  • 11
    • 77955578720 scopus 로고    scopus 로고
    • Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test
    • Chaviaras S, Mak P, Ralph D, Krishnan L, Broadbear JH. Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test. Psychopharmacology. 2010 ; 210: 35-43
    • (2010) Psychopharmacology , vol.210 , pp. 35-43
    • Chaviaras, S.1    Mak, P.2    Ralph, D.3    Krishnan, L.4    Broadbear, J.H.5
  • 12
    • 0027932914 scopus 로고
    • Ethopharmacological analysis of rat behavior on the elevated plus maze
    • Cruz APM, Frei F, Graeff FG. Ethopharmacological analysis of rat behavior on the elevated plus maze. Pharmacol Biochem Behav. 1994 ; 49: 171-176
    • (1994) Pharmacol Biochem Behav , vol.49 , pp. 171-176
    • Apm, C.1    Frei, F.2    Graeff, F.G.3
  • 13
    • 0028934728 scopus 로고
    • Use of the elevated plus maze in the search for novel anxiolytic agents
    • Dawson GR, Tricklebank MD. Use of the elevated plus maze in the search for novel anxiolytic agents. TiPS. 1995 ; 16: 33-36
    • (1995) TiPS , vol.16 , pp. 33-36
    • Dawson, G.R.1    Tricklebank, M.D.2
  • 14
    • 0030963916 scopus 로고    scopus 로고
    • Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression
    • Detke MJ, Johnson J, Lucki I. Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression. Exp Clin Psychopharmacol. 1997 ; 5: 107-112
    • (1997) Exp Clin Psychopharmacol , vol.5 , pp. 107-112
    • Detke, M.J.1    Johnson, J.2    Lucki, I.3
  • 15
    • 49349091548 scopus 로고    scopus 로고
    • Dissociation of the anxiolytic-like effects of Avpr1a and Avpr1b receptor antagonists in the dorsal and ventral hippocampus
    • Engin E, Treit D. Dissociation of the anxiolytic-like effects of Avpr1a and Avpr1b receptor antagonists in the dorsal and ventral hippocampus. Neuropeptides. 2008 ; 42: 411-421
    • (2008) Neuropeptides , vol.42 , pp. 411-421
    • Engin, E.1    Treit, D.2
  • 16
    • 0031686987 scopus 로고    scopus 로고
    • Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation
    • Engstrom T, Barth T, Melin P, et al. Oxytocin receptor binding and uterotonic activity of carbetocin and its metabolites following enzymatic degradation. Eur J Pharmacol. 1998 ; 355: 203-210
    • (1998) Eur J Pharmacol , vol.355 , pp. 203-210
    • Engstrom, T.1    Barth, T.2    Melin, P.3
  • 18
    • 0025368727 scopus 로고
    • Characterisation of the phenomenon of "one-trial tolerance" to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze
    • File SE, Mabbutt PS, Hitchcott PK. Characterisation of the phenomenon of "one-trial tolerance" to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze. Psychopharmacology. 1990 ; 102: 98-101
    • (1990) Psychopharmacology , vol.102 , pp. 98-101
    • File, S.E.1    Mabbutt, P.S.2    Hitchcott, P.K.3
  • 19
  • 20
    • 40849099938 scopus 로고    scopus 로고
    • The vasopressin system-from antidiuresis to psychopathology
    • Frank E, Landgraf R. The vasopressin system-from antidiuresis to psychopathology. Eur J Pharmacol. 2008 ; 583: 226-242
    • (2008) Eur J Pharmacol , vol.583 , pp. 226-242
    • Frank, E.1    Landgraf, R.2
  • 21
    • 0030001689 scopus 로고
    • Reduction of plasma oxytocin levels in patients suffering from major depression
    • Frasch A, Zetzsche T, Steiger A, et al. Reduction of plasma oxytocin levels in patients suffering from major depression. Adv Exp Med Biol. 1995 ; 395: 257-258
    • (1995) Adv Exp Med Biol , vol.395 , pp. 257-258
    • Frasch, A.1    Zetzsche, T.2    Steiger, A.3
  • 22
  • 23
    • 0022587582 scopus 로고
    • Vasopressin and oxytocin: Hypothalamic modulators of the stress response: A review
    • Gibbs DM. Vasopressin and oxytocin: hypothalamic modulators of the stress response: a review. Psychoendocrinology. 1986 ; 11: 131-140
    • (1986) Psychoendocrinology , vol.11 , pp. 131-140
    • Gibbs, D.M.1
  • 24
    • 14644388750 scopus 로고    scopus 로고
    • Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin
    • Gimpl G, Postina R, Fahrenholz F, et al. Binding domains of the oxytocin receptor for the selective oxytocin receptor antagonist barusiban in comparison to the agonists oxytocin and carbetocin. Eur J Pharmacol. 2005 ; 510: 9-16
    • (2005) Eur J Pharmacol , vol.510 , pp. 9-16
    • Gimpl, G.1    Postina, R.2    Fahrenholz, F.3
  • 26
    • 0030813322 scopus 로고    scopus 로고
    • Risk assessment behaviour: Evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test
    • Griebel G, Rodgers RJ, Perrault G, et al. Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test. Pharmacol Biochem Behav. 1997 ; 57: 817-827
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 817-827
    • Griebel, G.1    Rodgers, R.J.2    Perrault, G.3
  • 27
    • 0037197989 scopus 로고    scopus 로고
    • Anxiolytic-and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders
    • Griebel G, Simiand J, Gal CS, et al. Anxiolytic-and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc Natl Acad Sci USA. 2002 ; 99: 6370-6375
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6370-6375
    • Griebel, G.1    Simiand, J.2    Gal, C.S.3
  • 28
    • 0021183219 scopus 로고
    • Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour
    • Handley SL, Mithani S. Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour. Naunyn-Schmiedeberg's Arch Pharmacol. 1984 ; 327: 1-5
    • (1984) Naunyn-Schmiedeberg's Arch Pharmacol , vol.327 , pp. 1-5
    • Handley, S.L.1    Mithani, S.2
  • 29
    • 16444367602 scopus 로고    scopus 로고
    • Vasopressin and OT excite distinct neuronal populations in the central amygdala
    • Huber D, Veinante P, Stoop R. Vasopressin and OT excite distinct neuronal populations in the central amygdala. Science. 2005 ; 308: 245-248
    • (2005) Science , vol.308 , pp. 245-248
    • Huber, D.1    Veinante, P.2    Stoop, R.3
  • 30
    • 0033556679 scopus 로고    scopus 로고
    • Oxytocin, vasopressin, and autism: Is there a connection?
    • Insel TR, O'Brien DJ, Leckman JF. Oxytocin, vasopressin, and autism: is there a connection?. Biol Psychiatry. 1999 ; 45: 145-157
    • (1999) Biol Psychiatry , vol.45 , pp. 145-157
    • Insel, T.R.1    O'Brien, D.J.2    Leckman, J.F.3
  • 31
    • 0033846580 scopus 로고    scopus 로고
    • Abecarnil and alprazolam reverse anxiety-like behaviors induced by ethanol withdrawal
    • Jung ME, Wallis CJ, Gatch MB, et al. Abecarnil and alprazolam reverse anxiety-like behaviors induced by ethanol withdrawal. Alcohol. 2000 ; 21: 161-168
    • (2000) Alcohol , vol.21 , pp. 161-168
    • Jung, M.E.1    Wallis, C.J.2    Gatch, M.B.3
  • 32
    • 30544438866 scopus 로고    scopus 로고
    • Oxytocin modulates neural circuitry for social cognition and fear in humans
    • Kirsch P, Esslinger C, Chen Q, Mier D, Lis S, Siddhanti S, et al. Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci. 2005 ; 25: 11489-11493
    • (2005) J Neurosci , vol.25 , pp. 11489-11493
    • Kirsch, P.1    Esslinger, C.2    Chen, Q.3    Mier, D.4    Lis, S.5    Siddhanti, S.6
  • 33
    • 67749117820 scopus 로고    scopus 로고
    • Modulatory effects of oxytocin and carbetocin on stress-induced changes in rat behavior in the open-field
    • Klenerova V, Krejci I, Sida P, Hlinak Z, Hynie S. Modulatory effects of oxytocin and carbetocin on stress-induced changes in rat behavior in the open-field. J Physiol Pharmacol. 2009 ; 60: 57-62
    • (2009) J Physiol Pharmacol , vol.60 , pp. 57-62
    • Klenerova, V.1    Krejci, I.2    Sida, P.3    Hlinak, Z.4    Hynie, S.5
  • 34
    • 10444276636 scopus 로고    scopus 로고
    • Vasopressin and oxytocin release within the brain: A dynamic concept of multiple and variable modes of neuropeptide communication
    • Landgraf R, Neumann ID. Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication. Front Neuroendocrinol. 2004 ; 25: 150-176
    • (2004) Front Neuroendocrinol , vol.25 , pp. 150-176
    • Landgraf, R.1    Neumann, I.D.2
  • 35
    • 0028981589 scopus 로고
    • V1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities and anxiety-related behavior in rats
    • Landgraf R, Gerstberger R, Montkowski A, et al. V1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities and anxiety-related behavior in rats. J Neurosci. 1995 ; 15: 4250-4258
    • (1995) J Neurosci , vol.15 , pp. 4250-4258
    • Landgraf, R.1    Gerstberger, R.2    Montkowski, A.3
  • 36
    • 0030592582 scopus 로고    scopus 로고
    • Septal vasopressin modulates anxiety-related behaviour in rats
    • Liebsch G, Wotjak CT, Landgraf R, Engelmann M. Septal vasopressin modulates anxiety-related behaviour in rats. Neurosci Lett. 1996 ; 217: 101-104
    • (1996) Neurosci Lett , vol.217 , pp. 101-104
    • Liebsch, G.1    Wotjak, C.T.2    Landgraf, R.3    Engelmann, M.4
  • 37
    • 0028802527 scopus 로고
    • Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: Comparisons with atosiban
    • Manning M, Miteva K, Pancheva S, Stoev S, Wo NC, Chan WY. Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with atosiban. Int J Peptide Protein Res. 1995 ; 46: 244-252
    • (1995) Int J Peptide Protein Res , vol.46 , pp. 244-252
    • Manning, M.1    Miteva, K.2    Pancheva, S.3    Stoev, S.4    Wo, N.C.5    Chan, W.Y.6
  • 38
    • 0037900873 scopus 로고    scopus 로고
    • Female oxytocin-deficient mice display enhanced anxiety-related behavior
    • Mantella RC, Vollmer RR, Li X, et al. Female oxytocin-deficient mice display enhanced anxiety-related behavior. Endocrinology. 2003 ; 144: 2291-2296
    • (2003) Endocrinology , vol.144 , pp. 2291-2296
    • Mantella, R.C.1    Vollmer, R.R.2    Li, X.3
  • 39
    • 0343113397 scopus 로고    scopus 로고
    • An anxiolytic action of oxytocin is enhanced by estrogen in the mouse
    • McCarthy MM, McDonald CH, Brooks PJ, et al. An anxiolytic action of oxytocin is enhanced by estrogen in the mouse. Physiol Behav. 1996 ; 60: 1209-1215
    • (1996) Physiol Behav , vol.60 , pp. 1209-1215
    • McCarthy, M.M.1    McDonald, C.H.2    Brooks, P.J.3
  • 40
    • 0345422720 scopus 로고    scopus 로고
    • Vasopressin V2 (SR121463A) and V1A (SR49059) receptor antagonists both inhibit desmopressin vasorelaxing activity
    • Mechaly I, Laurent F, Portet K, Serrano JJ, Cros G. Vasopressin V2 (SR121463A) and V1A (SR49059) receptor antagonists both inhibit desmopressin vasorelaxing activity. Eur J Pharmacol. 1999 ; 383: 287-290
    • (1999) Eur J Pharmacol , vol.383 , pp. 287-290
    • Mechaly, I.1    Laurent, F.2    Portet, K.3    Serrano, J.J.4    Cros, G.5
  • 41
    • 0019522536 scopus 로고
    • Short-term behavioral effects of posterior pituitary peptides in mice
    • Meisenberg G. Short-term behavioral effects of posterior pituitary peptides in mice. Peptides. 1981 ; 2: 1-8
    • (1981) Peptides , vol.2 , pp. 1-8
    • Meisenberg, G.1
  • 42
    • 0030036620 scopus 로고    scopus 로고
    • Long-term use of benzodiazepines: Tolerance, dependence and clinical problems in anxiety and mood disorders
    • Michelini S, Cassano GB, Frare F, Perugi G. Long-term use of benzodiazepines: tolerance, dependence and clinical problems in anxiety and mood disorders. Pharmacopsychiatry. 1996 ; 29: 127-134
    • (1996) Pharmacopsychiatry , vol.29 , pp. 127-134
    • Michelini, S.1    Cassano, G.B.2    Frare, F.3    Perugi, G.4
  • 43
    • 45549103898 scopus 로고    scopus 로고
    • Brain oxytocin: A key regulator of emotional and social behaviours in both females and males
    • Neumann ID. Brain oxytocin: a key regulator of emotional and social behaviours in both females and males. J Neuroendocrinol. 2008 ; 20: 585-865
    • (2008) J Neuroendocrinol , vol.20 , pp. 585-865
    • Neumann, I.D.1
  • 44
    • 0027732230 scopus 로고
    • Simultaneous microdialysis in blood and brain: Oxytocin and vasopressin release in response to central and peripheral osmotic stimulation and suckling in the rat
    • Neumann ID, Ludwig M, Engelmann M, Pittman QJ, Landgraf R. Simultaneous microdialysis in blood and brain: oxytocin and vasopressin release in response to central and peripheral osmotic stimulation and suckling in the rat. Neuroendocrinology. 1993 ; 58: 637-645
    • (1993) Neuroendocrinology , vol.58 , pp. 637-645
    • Neumann, I.D.1    Ludwig, M.2    Engelmann, M.3    Pittman, Q.J.4    Landgraf, R.5
  • 45
    • 0034704444 scopus 로고    scopus 로고
    • Brain oxytocin inhibits the (re)activity of the hypothalamopituitary- adrenal axis in male rats: Involvement of hypothalamic and limbic brain regions
    • Neumann ID, Kromer SA, Toschi N, Ebner K. Brain oxytocin inhibits the (re)activity of the hypothalamopituitary-adrenal axis in male rats: involvement of hypothalamic and limbic brain regions. Regul Pept. 2000 ; 96: 31-38
    • (2000) Regul Pept , vol.96 , pp. 31-38
    • Neumann, I.D.1    Kromer, S.A.2    Toschi, N.3    Ebner, K.4
  • 46
    • 0036968107 scopus 로고    scopus 로고
    • Role of neuropeptides in antidepressant and memory improving effects of venlafaxine
    • Nowakowska E, Kus K, Bobkiewicz-Kozlowska T, et al. Role of neuropeptides in antidepressant and memory improving effects of venlafaxine. Polish Journal of Pharmacology. 2002 ; 54: 605-613
    • (2002) Polish Journal of Pharmacology , vol.54 , pp. 605-613
    • Nowakowska, E.1    Kus, K.2    Bobkiewicz-Kozlowska, T.3
  • 47
    • 0022374863 scopus 로고
    • Validation of open: Closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Pellow S, Chopin P, File SE, Briley M. Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 1985 ; 14: 149-167
    • (1985) J Neurosci Methods , vol.14 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 48
    • 0030032350 scopus 로고    scopus 로고
    • Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression
    • Purba JS, Hoogendijk WJG, Hofman MA, et al. Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression. Arch Gen Psychiatry. 1996 ; 53: 137-143
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 137-143
    • Purba, J.S.1    Wjg, H.2    Hofman, M.A.3
  • 49
    • 11844286907 scopus 로고    scopus 로고
    • The central vasopressinergic system: Examining the opportunities for psychiatric drug development
    • Ring RH. The central vasopressinergic system: examining the opportunities for psychiatric drug development. Curr Pharm Design. 2005 ; 11: 205-225
    • (2005) Curr Pharm Design , vol.11 , pp. 205-225
    • Ring, R.H.1
  • 50
    • 33644848493 scopus 로고    scopus 로고
    • Anxiolytic-like activity of oxytocin in male mice: Behavioral and autonomic evidence, therapeutic implications
    • Ring RH, Malberg JE, Potestio L, et al. Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications. Psychopharmacology. 2006 ; 185: 218-225
    • (2006) Psychopharmacology , vol.185 , pp. 218-225
    • Ring, R.H.1    Malberg, J.E.2    Potestio, L.3
  • 51
    • 34548166508 scopus 로고    scopus 로고
    • Basis and therapeutical rationale of the urinary concentrating mechanism
    • Rittig S, Frøkiær J. Basis and therapeutical rationale of the urinary concentrating mechanism. Int J Clin Pract. 2007 ; 61: 2-7
    • (2007) Int J Clin Pract , vol.61 , pp. 2-7
    • Rittig, S.1    Frøkiær, J.2
  • 52
    • 71549132494 scopus 로고    scopus 로고
    • Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
    • Slattery DA, Neumann ID. Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats. Neuropharmacology. 2010 ; 58: 56-61
    • (2010) Neuropharmacology , vol.58 , pp. 56-61
    • Slattery, D.A.1    Neumann, I.D.2
  • 53
    • 0024477222 scopus 로고
    • Anticonflict and rotarod impairing effects of alprazolam and diazepam in rat after acute and subchronic administration
    • Soderpalm B, Eriksson E, Engel JA. Anticonflict and rotarod impairing effects of alprazolam and diazepam in rat after acute and subchronic administration. Prog Neuropsychopharmacol Biol Psychiatry. 1989 ; 13: 269-283
    • (1989) Prog Neuropsychopharmacol Biol Psychiatry , vol.13 , pp. 269-283
    • Soderpalm, B.1    Eriksson, E.2    Engel, J.A.3
  • 54
    • 0026707275 scopus 로고
    • Oxytocin and vasopressin hexapeptide fragments have opposing influences on conditioned freezing behavior
    • Stoehr JD, Cramer CP, North WG. Oxytocin and vasopressin hexapeptide fragments have opposing influences on conditioned freezing behavior. Psychoneuroendocrinology. 1992 ; 17: 267-271
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 267-271
    • Stoehr, J.D.1    Cramer, C.P.2    North, W.G.3
  • 55
    • 0022000317 scopus 로고
    • Evidence that tolerance develops to the anxiolytic effect of diazepam in rats
    • Treit D. Evidence that tolerance develops to the anxiolytic effect of diazepam in rats. Pharmacol Biochem Behav. 1985 ; 22: 383-387
    • (1985) Pharmacol Biochem Behav , vol.22 , pp. 383-387
    • Treit, D.1
  • 56
    • 0345059241 scopus 로고    scopus 로고
    • Oxytocin may mediate the benefits of positive social interaction and emotions
    • Uvnas-Moberg K. Oxytocin may mediate the benefits of positive social interaction and emotions. Psychoneuroendocrinology. 1998 ; 23: 819-835
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 819-835
    • Uvnas-Moberg, K.1
  • 57
    • 20444394368 scopus 로고    scopus 로고
    • The psychobiology of emotion: The role of the oxytocinergic system
    • Uvnäs-Moberg K, Arn I, Magnusson D. The psychobiology of emotion: the role of the oxytocinergic system. Int J Behav Med. 2005 ; 12: 59-65
    • (2005) Int J Behav Med , vol.12 , pp. 59-65
    • Uvnäs-Moberg, K.1    Arn, I.2    Magnusson, D.3
  • 58
    • 0019815198 scopus 로고
    • Inhibitory and stimulatory action of vasopressin on the secretion of corticotrophin in rats: Structure-activity study
    • Van Dijk AMA, Lodewijks HMJM, van Ree JM, van Wimersma Greidanus TB. Inhibitory and stimulatory action of vasopressin on the secretion of corticotrophin in rats: structure-activity study. Life Sci. 1981 ; 29: 1107-1116
    • (1981) Life Sci , vol.29 , pp. 1107-1116
    • Van Dijk Ama1    Hmjm, L.2    Van Ree, J.M.3    Van Wimersma Greidanus, T.B.4
  • 59
    • 36749059489 scopus 로고    scopus 로고
    • Centrally released oxytocin mediates mating-induced anxiolysis in male rats
    • Waldherr M, Neumann ID. Centrally released oxytocin mediates mating-induced anxiolysis in male rats. Proc Natl Acad Sci USA. 2007 ; 104: 16,681-16,684
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16
    • Waldherr, M.1    Neumann, I.D.2
  • 60
    • 34347207241 scopus 로고    scopus 로고
    • The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
    • Walf AA, Frye CA. The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nature Protocols. 2007 ; 2: 322-328
    • (2007) Nature Protocols , vol.2 , pp. 322-328
    • Walf, A.A.1    Frye, C.A.2
  • 61
    • 0030924818 scopus 로고    scopus 로고
    • Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats
    • Windle RJ, Shanks N, Lightman SL, Ingram CD. Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats. Endocrinology. 1997 ; 138: 2829-2834
    • (1997) Endocrinology , vol.138 , pp. 2829-2834
    • Windle, R.J.1    Shanks, N.2    Lightman, S.L.3    Ingram, C.D.4
  • 62
    • 1642505806 scopus 로고    scopus 로고
    • Oxytocin attenuates stress-induced c-fos mRNA expression in specific forebrain regions associated with modulation of hypothalamo-pituitary-adrenal activity
    • Windle RJ, Kershaw YM, Shanks N, Wood SA, Lightman SL, Ingram CD. Oxytocin attenuates stress-induced c-fos mRNA expression in specific forebrain regions associated with modulation of hypothalamo-pituitary-adrenal activity. J Neurosci. 2004 ; 24: 2974-2982
    • (2004) J Neurosci , vol.24 , pp. 2974-2982
    • Windle, R.J.1    Kershaw, Y.M.2    Shanks, N.3    Wood, S.A.4    Lightman, S.L.5    Ingram, C.D.6
  • 63
    • 0029860680 scopus 로고    scopus 로고
    • Release of vasopressin within the rat paraventricular nucleus in response to emotional stress: A novel mechanism of regulating adrenocorticotropic hormone secretion?
    • Wotjak CT, Kubota M, Liebsch G, Montkowski A, Holsboer F, Neumann I, Landgraf R. Release of vasopressin within the rat paraventricular nucleus in response to emotional stress: a novel mechanism of regulating adrenocorticotropic hormone secretion?. J Neurosci. 1996 ; 16: 7725-7732
    • (1996) J Neurosci , vol.16 , pp. 7725-7732
    • Wotjak, C.T.1    Kubota, M.2    Liebsch, G.3    Montkowski, A.4    Holsboer, F.5    Neumann, I.6    Landgraf, R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.