A chemical genetic approach for covalent inhibition of analogue-sensitive Aurora kinase

ACS Chemical Biology

Volumn 7, Issue 4, 2012, Pages 723-731

  Koch, André ^a   Rode, Haridas B ^b,c   Richters, André ^b   Rauh, Daniel ^b,d   Hauf, Silke ^a  

^a FRIEDRICH MIESCHER LABORATORY OF THE MAX PLANCK SOCIETY   (Germany)

^b CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY   (Germany)

^c NATIONAL CHEMICAL LABORATORY   (India)

^d TU DORTMUND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 [1 [[4 [(3 BROMOPHENYL)AMINO] 6 (BUT 2 YNAMIDO)QUINAZOLIN 7 YL]OXY] 12 OXO 3,6,9 TRIOXA 11 AZATETRADECAN 14 YL] 5,5 DIFLUORO 7,9 DIMETHYL 5H DIPYRROLO[1,2 C:2',1' F ][1,3,2]DIAZABORININ 4 IUM 5 UIDE; 3 [1 [[4 [(3 BROMOPHENYL)AMINO] 6 PROPIOLAMIDOQUINAZOLIN 7 YL]OXY] 12 OXO 3,6,9 TRIOXA 11 AZATETRADECAN 14 YL] 5,5 DIFLUORO 7,9 DIMETHYL 5H DIPYRROLO[1,2 C:2',1' F ][1,3,2]DIAZABORININ 4 IUM 5 UIDE; 3 [1 [[6 AMINO 4 [(3 BROMOPHENYL)AMINO]QUINAZOLIN 7 YL]OXY] 12 OXO 3,6,9 TRIOXA 11 AZATETRADECAN 14 YL] 5,5 DIFLUORO 7,9 DIMETHYL 5H DIPYRROLO[1,2 C:2',1' F ][1,3,2]DIAZABORININ 4 IUM 5 UIDE; AURORA KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMISTRY; CELL ASSAY; CHEMICAL GENETICS; NONHUMAN; PRIORITY JOURNAL; YEAST;

ANILINE COMPOUNDS; DRUG DESIGN; GENETIC ENGINEERING; MOLECULAR CONFORMATION; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; QUINAZOLINES; SCHIZOSACCHAROMYCES;

EID: 84860180621     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb200465c     Document Type: Article

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