Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro

Journal of Neuroimmunology

Volumn 246, Issue 1-2, 2012, Pages 85-95

  Lisak, Robert P ^a,b   Benjamins, Joyce A ^a,b   Nedelkoska, Liljana ^a   Barger, Jennifer L ^a   Ragheb, Samia ^a,b   Fan, Boli ^c,d   Ouamara, Nadia ^c,d   Johnson, Trina A ^c,d   Rajasekharan, Sathyanath ^c,d   Bar Or, Amit ^c,d  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

B cells; Cytokines; Microglia; Multiple sclerosis; Oligodendroglia

Indexed keywords

B LYMPHOCYTE ANTIGEN RECEPTOR; CD40 LIGAND; CYTOKINE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 6; LYMPHOCYTE ANTIGEN RECEPTOR; LYMPHOTOXIN; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ARTICLE; ASTROCYTE; B LYMPHOCYTE; CELL INTERACTION; CELL ISOLATION; CELL SECRETION; CELL STIMULATION; CELL STRUCTURE; CLINICAL ARTICLE; COMPLEMENT INHIBITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DEMYELINATION; FEMALE; GLIA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MULTIPLE SCLEROSIS; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; SUPERNATANT;

ANIMALS; ANIMALS, NEWBORN; B-LYMPHOCYTE SUBSETS; CELL DEATH; CELL-FREE SYSTEM; CELLS, CULTURED; HUMANS; MICROGLIA; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; OLIGODENDROGLIA; RATS;

EID: 84860147831     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.02.015     Document Type: Article

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