Protective effects of astragalosides on dexamethasone and Aβ 25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats

Food and Chemical Toxicology

Volumn 50, Issue 6, 2012, Pages 1883-1890

  Li, Wei Zu ^a   Wu, Wang Yang ^a   Huang, Da Ke ^a   Yin, Yan Yan ^a   Kan, Hong Wei ^b   Wang, Xin ^a   Yao, Yu You ^a   Li, Wei Ping ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Anhui Institute of Materia Medica   (China)

Author keywords

A 25 35; APP; Astragalosides; Dexamethasone; Memory and learning impairment

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; ASTRAGALOSIDES; BETA SECRETASE; DEXAMETHASONE; GINSENOSIDE RG 1; NEUROPROTECTIVE AGENT; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTRAGALUS MEMBRANACEUS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HIPPOCAMPAL CA1 REGION; LEARNING DISORDER; MALE; MEMORY DISORDER; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PLANT ROOT; RAT;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BISBENZIMIDAZOLE; BRAIN; COLORING AGENTS; DEXAMETHASONE; DNA, COMPLEMENTARY; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUCOCORTICOIDS; IMMUNOHISTOCHEMISTRY; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY DISORDERS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SAPONINS;

ASTRAGALUS MEMBRANACEUS; RATTUS;

EID: 84860142445     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.03.064     Document Type: Article

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