Effect of extract of astragalus on inflammatory factor and apoptosis after focal cerebral ischemia/reperfusion injury in rats

Chinese Pharmacological Bulletin

Volumn 21, Issue 12, 2005, Pages 1486-1489

  Yin, Yan Yan ^a   Li, Wei Ping ^a   Wang, Shao Bin ^a   He, Ting ^a   Ming, Liang ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Extract of astragalus; Inflammatory factor; Ischemia reperfusion

Indexed keywords

ASTRAGALUS EXTRACT; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; MIDDLE CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; RADIOIMMUNOASSAY; RAT; REPERFUSION INJURY;

EID: 32344433356     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Liu T, Clark RK, Modonnel PR et al. Tumor necrosis factor-α expression in ischemic neurons[J]. Stroke, 1994, 25(7): 1481-8.
2. Saito K, Swyana K, Nishda et al. Early increase in TNF-α, IL-6 and IL-1 levels following transient cebebral ischemia in gerbil brain [J]. Neurosci lett, 1996, 206(2):149-52.
3. Wang X, Baronc F C, Aiyar NV et al. Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats[J]. Stroke, 1997, 28(1):155-61.
4. Akopov SE, Simonian NA, Grigorian GS. Dynamic polymorphonuclear leukocyteaccumulation in acute cerebral infarction and their correlation with brain tissue damage[J]. Stroke, 1996, 27:1739-43.
5. Thomas J, DeGraba, MD. The role of inflammation after acute stroke[J]. Neurol, 1998, 51(33):62-8.
6. Bame FC, Arvin B, White RF et al. Tumor necrosis factor-α mediator of focal ischemic brain injury[J]. Stroke, 1997, 28(6): 1233-43.
7. Meyer R, Weissert R, Diem R et al. Acute neuronal apoptosis in a rat model of multiple sclerosis[J]. Neurosci, 2001, 21(16): 6214-20.
8. Rosenberg PA, Azenman E. Hundred-fold increase in neuronal vulner-ability to glutamate toxicity in astrocyte-poorcultures of rat cereb-ral cortex[J]. Neuro Lett, 1998, 103(2):162-72.