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Volumn 19, Issue 3, 2012, Pages 160-169

Thyroid fine needle aspirate: A post-Bethesda update

Author keywords

bethesda; BRAF; fine needle aspirate; genetic abnormalities; KRAS; thyroid

Indexed keywords

MICRORNA; MOLECULAR MARKER; PROTEIN PATCHED; PROTEIN RET; RAS PROTEIN; TRANSCRIPTION FACTOR PAX8;

EID: 84860011284     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e3182534610     Document Type: Review
Times cited : (13)

References (109)
  • 1
    • 84856497560 scopus 로고    scopus 로고
    • Available at: Accessed November 10, 2011
    • SEER Stat Fact Sheets: Thyroid. 2012; Available at: http:// seer.cancer.gov/statfacts/html/thyro.html. Accessed November 10, 2011.
    • (2012) SEER Stat Fact Sheets: Thyroid.
  • 2
    • 66649112355 scopus 로고    scopus 로고
    • International patterns and trends in thyroid cancer incidence, 1973- 2002
    • Kilfoy BA, Zheng T, Holford TR, et al. International patterns and trends in thyroid cancer incidence, 1973-2002. Cancer Causes Control. 2009;20:525-531.
    • (2009) Cancer Causes Control. , vol.20 , pp. 525-531
    • Kilfoy, B.A.1    Zheng, T.2    Holford, T.R.3
  • 3
    • 0031028402 scopus 로고    scopus 로고
    • Prognostic factors for thyroid carcinoma: A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) program 1973-1991
    • DOI 10.1002/(SICI)1097-0142(19970201)79:3<564::AID-CNCR20>3.0.CO;2- 0
    • Gilliland FD, Hunt WC, Morris DM, et al. Prognostic factors for thyroid carcinoma. A population-based study of 15,698 cases from the Surveillance, Epidemiology and End Results (SEER) program 1973-1991. Cancer. 1997;79:564-573. (Pubitemid 27051783)
    • (1997) Cancer , vol.79 , Issue.3 , pp. 564-573
    • Gilliland, F.D.1    Hunt, W.C.2    Morris, D.M.3    Key, C.R.4
  • 4
    • 67649993396 scopus 로고    scopus 로고
    • Future of cancer incidence in the United States: Burdens upon an aging, changing nation
    • Smith BD, Smith GL, Hurria A, et al. Future of cancer incidence in the United States: burdens upon an aging, changing nation. J Clin Oncol. 2009;27:2758-2765.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2758-2765
    • Smith, B.D.1    Smith, G.L.2    Hurria, A.3
  • 5
    • 77149130906 scopus 로고    scopus 로고
    • American association of clinical endocrinologists and associazione medici endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules
    • Gharib H, Papini E, Valcavi R, et al. American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract. 2006;12:63-102.
    • (2006) Endocr. Pract. , vol.12 , pp. 63-102
    • Gharib, H.1    Papini, E.2    Valcavi, R.3
  • 6
    • 43149085821 scopus 로고    scopus 로고
    • The national cancer institute thyroid fine needle aspiration state of the science conference: A summation
    • Baloch ZW, Cibas ES, Clark DP, et al. The National Cancer Institute Thyroid fine needle aspiration state of the science conference: a summation. Cytojournal. 2008;5:6.
    • (2008) Cytojournal. , vol.5 , pp. 6
    • Baloch, Z.W.1    Cibas, E.S.2    Clark, D.P.3
  • 7
    • 70449730819 scopus 로고    scopus 로고
    • The Bethesda system for reporting thyroid cytopathology
    • Cibas ES, Ali SZ. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2009;132:658-665.
    • (2009) Am. J. Clin. Pathol. , vol.132 , pp. 658-665
    • Cibas, E.S.1    Ali, S.Z.2
  • 8
    • 70449370231 scopus 로고    scopus 로고
    • Revised american thyroid association management guidelines for patients with thyroid nodules and differentiated thyroid cancer
    • Cooper DS, Doherty GM, Haugen BR, et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid. 2009;19:1167-1214.
    • (2009) Thyroid. , vol.19 , pp. 1167-1214
    • Cooper, D.S.1    Doherty, G.M.2    Haugen, B.R.3
  • 9
    • 84859962991 scopus 로고    scopus 로고
    • The use of the bethesda terminology in thyroid fine - Needle aspiration results in a lower rate of surgery for nonmalignant nodules: A report from a reference center in turkey
    • Ozluk Y, Pehlivan E, Gulluoglu MG, et al. The use of the Bethesda terminology in thyroid fine-needle aspiration results in a lower rate of surgery for nonmalignant nodules: a report from a reference center in Turkey. Int J Surg Pathol. 2011; 19:761-771.
    • (2011) Int. J. Surg. Pathol. , vol.19 , pp. 761-771
    • Ozluk, Y.1    Pehlivan, E.2    Gulluoglu, M.G.3
  • 10
    • 84856397016 scopus 로고    scopus 로고
    • The impact of implementation of the bethesda system for reporting thyroid cytopathology on the quality of reporting, 'risk' of malignancy, surgical rate, and rate of frozen sections requested for thyroid lesions
    • Crowe A, Linder A, Hameed O, et al. The impact of implementation of the Bethesda System for Reporting Thyroid Cytopathology on the quality of reporting, 'risk' of malignancy, surgical rate, and rate of frozen sections requested for thyroid lesions. Cancer Cytopathol. 2011;119: 315-321.
    • (2011) Cancer Cytopathol. , vol.119 , pp. 315-321
    • Crowe, A.1    Linder, A.2    Hameed, O.3
  • 11
    • 70449364033 scopus 로고    scopus 로고
    • The Bethesda thyroid fine-needle aspiration classification system: Year 1 at an academic institution
    • Theoharis CG, Schofield KM, Hammers L, et al. The Bethesda thyroid fine-needle aspiration classification system: year 1 at an academic institution. Thyroid. 2009;19:1215-1223.
    • (2009) Thyroid. , vol.19 , pp. 1215-1223
    • Theoharis, C.G.1    Schofield, K.M.2    Hammers, L.3
  • 12
    • 79959586160 scopus 로고    scopus 로고
    • Sensitivity of fine-needle aspiration for papillary carcinoma of the thyroid correlates with tumor size
    • Renshaw AA. Sensitivity of fine-needle aspiration for papillary carcinoma of the thyroid correlates with tumor size. Diagn Cytopathol. 2011;39:471-474.
    • (2011) Diagn. Cytopathol. , vol.39 , pp. 471-474
    • Renshaw, A.A.1
  • 13
    • 84860006165 scopus 로고    scopus 로고
    • High sensitivity and positive predictive value of fine-needle aspiration for uncommon thyroid malignancies
    • Epub ahead of print]
    • Dustin SM, Jo VY, Hanley KZ, et al. High sensitivity and positive predictive value of fine-needle aspiration for uncommon thyroid malignancies. Diagn Cytopathol. 2011 [Epub ahead of print].
    • (2011) Diagn. Cytopathol.
    • Dustin, S.M.1    Jo, V.Y.2    Hanley, K.Z.3
  • 14
    • 78049491899 scopus 로고    scopus 로고
    • An estimate of risk of malignancy for a benign diagnosis in thyroid fine-needle aspirates
    • Renshaw A. An estimate of risk of malignancy for a benign diagnosis in thyroid fine-needle aspirates. Cancer Cytopathol. 2010;118:190-195.
    • (2010) Cancer Cytopathol. , vol.118 , pp. 190-195
    • Renshaw, A.1
  • 17
    • 33644785857 scopus 로고    scopus 로고
    • The impact of assessing specimen adequacy and number of needle passes for fine-needle aspiration biopsy of thyroid nodules
    • DOI 10.1089/thy.2006.16.55
    • Redman R, Zalaznick H, Mazzaferri EL, et al. The impact of assessing specimen adequacy and number of needle passes for fine-needle aspiration biopsy of thyroid nodules. Thyroid. 2006;16:55-60. (Pubitemid 43346504)
    • (2006) Thyroid , vol.16 , Issue.1 , pp. 55-60
    • Redman, R.1    Zalaznick, H.2    Mazzaferri, E.L.3    Massoll, N.A.4
  • 18
    • 0033737109 scopus 로고    scopus 로고
    • Ultrasound-guided fineneedle aspiration biopsy of the thyroid: Role of on-site assessment and multiple cytologic preparations
    • Baloch ZW, Tam D, Langer J, et al. Ultrasound-guided fineneedle aspiration biopsy of the thyroid: role of on-site assessment and multiple cytologic preparations. Diagn Cytopathol. 2000; 23:425-429.
    • (2000) Diagn. Cytopathol. , vol.23 , pp. 425-429
    • Baloch, Z.W.1    Tam, D.2    Langer, J.3
  • 20
    • 1842429850 scopus 로고    scopus 로고
    • False-Negative Fine-Needle Aspiration Cytology Results Delay Treatment and Adversely Affect Outcome in Patients with Thyroid Carcinoma
    • DOI 10.1089/105072504773297885
    • Yeh MW, Demircan O, Ituarte P, et al. False-negative fineneedle aspiration cytology results delay treatment and adversely affect outcome in patients with thyroid carcinoma. Thyroid. 2004;14:207-215. (Pubitemid 38452193)
    • (2004) Thyroid , vol.14 , Issue.3 , pp. 207-215
    • Yeh, M.W.1    Demircan, O.2    Ituarte, P.3    Clark, O.H.4
  • 21
    • 70149119767 scopus 로고    scopus 로고
    • The indeterminate thyroid fine-needle aspiration experience from an academic center using terminology similar to that proposed in the 2007 national cancer institute thyroid fine needle aspiration state of the science conference
    • Nayar R, Ivanovic M. The indeterminate thyroid fine-needle aspiration experience from an academic center using terminology similar to that proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Cancer. 2009;117:195-202.
    • (2009) Cancer , vol.117 , pp. 195-202
    • Nayar, R.1    Ivanovic, M.2
  • 22
    • 77957701045 scopus 로고    scopus 로고
    • Fine-needle aspiration of follicular patterned lesions of the thyroid: diagnosis, management, and follow-up according to National Cancer Institute (NCI) recommendations
    • Faquin WC, Baloch ZW. Fine-needle aspiration of follicular patterned lesions of the thyroid: diagnosis, management, and follow-up according to National Cancer Institute (NCI) recommendations. Diagn Cytopathol. 2010;38:731-739.
    • (2010) Diagn. Cytopathol. , vol.38 , pp. 731-739
    • Faquin, W.C.1    Baloch, Z.W.2
  • 23
    • 77956599965 scopus 로고    scopus 로고
    • Malignancy risk for fineneedle aspiration of thyroid lesions according to the Bethesda system for reporting thyroid cytopathology
    • Jo VY, Stelow EB, Dustin SM, et al. Malignancy risk for fineneedle aspiration of thyroid lesions according to the Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2010;134:450-456.
    • (2010) Am. J. Clin. Pathol. , vol.134 , pp. 450-456
    • Jo, V.Y.1    Stelow, E.B.2    Dustin, S.M.3
  • 24
    • 70349339533 scopus 로고    scopus 로고
    • Implications of the proposed thyroid fine-needle aspiration category of 'follicular lesion of undetermined significance': A five-year multi-institutional analysis
    • Layfield LJ, Morton MJ, Cramer HM, et al. Implications of the proposed thyroid fine-needle aspiration category of 'follicular lesion of undetermined significance': a five-year multi-institutional analysis. Diagn Cytopathol. 2009;37: 710-714.
    • (2009) Diagn. Cytopathol. , vol.37 , pp. 710-714
    • Layfield, L.J.1    Morton, M.J.2    Cramer, H.M.3
  • 25
    • 78049511440 scopus 로고    scopus 로고
    • Should 'atypical follicular cells' in thyroid fineneedle aspirates be subclassified
    • Renshaw AA. Should 'atypical follicular cells' in thyroid fineneedle aspirates be subclassified? Cancer Cytopathol. 2010; 118:186-189.
    • (2010) Cancer Cytopathol. , vol.118 , pp. 186-189
    • Renshaw, A.A.1
  • 26
    • 83455258883 scopus 로고    scopus 로고
    • The atypia of undetermined significance/follicular lesion of undetermined significance: Malignant ratio: A proposed performance measure for reporting in the Bethesda system for thyroid cytopathology
    • Epub ahead of print]
    • Krane JF, Vanderlaan PA, Faquin WC, et al. The atypia of undetermined significance/follicular lesion of undetermined significance: malignant ratio: a proposed performance measure for reporting in the Bethesda system for thyroid cytopathology. Cancer Cytopathol. 2011 [Epub ahead of print].
    • (2011) Cancer Cytopathol.
    • Krane, J.F.1    Vanderlaan, P.A.2    Faquin, W.C.3
  • 28
    • 82755164521 scopus 로고    scopus 로고
    • The impact of atypia/follicular lesion of undetermined significance on the rate of malignancy in thyroid fine-needle aspiration: evaluation of the Bethesda system for reporting thyroid cytopathology
    • Broome JT, Solorzano CC. The impact of atypia/follicular lesion of undetermined significance on the rate of malignancy in thyroid fine-needle aspiration: evaluation of the Bethesda system for reporting thyroid cytopathology. Surgery. 2011;150:1234-1241.
    • (2011) Surgery , vol.150 , pp. 1234-1241
    • Broome, J.T.1    Solorzano, C.C.2
  • 29
    • 82555191091 scopus 로고    scopus 로고
    • Pathological definition and clinical significance of vascular invasion in thyroid carcinomas of follicular epithelial derivation
    • Mete O, Asa SL. Pathological definition and clinical significance of vascular invasion in thyroid carcinomas of follicular epithelial derivation. Mod Pathol. 2011;24:1545-1552.
    • (2011) Mod. Pathol. , vol.24 , pp. 1545-1552
    • Mete, O.1    Asa, S.L.2
  • 30
    • 55249098863 scopus 로고    scopus 로고
    • Interobserver and intraobserver variation among experts in the diagnosis of thyroid follicular lesions with borderline nuclear features of papillary carcinoma
    • Elsheikh TM, Asa SL, Chan JK, et al. Interobserver and intraobserver variation among experts in the diagnosis of thyroid follicular lesions with borderline nuclear features of papillary carcinoma. Am J Clin Pathol. 2008;130:736-744.
    • (2008) Am. J. Clin. Pathol. , vol.130 , pp. 736-744
    • Elsheikh, T.M.1    Asa, S.L.2    Chan, J.K.3
  • 31
    • 77949354084 scopus 로고    scopus 로고
    • Evidence-based evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies
    • Marchevsky AM, Walts AE, Bose S, et al. Evidence-based evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies. Diagn Cytopathol. 2010;38: 252-259.
    • (2010) Diagn. Cytopathol. , vol.38 , pp. 252-259
    • Marchevsky, A.M.1    Walts, A.E.2    Bose, S.3
  • 32
    • 84859997628 scopus 로고    scopus 로고
    • A simplified Bethesda system for reporting thyroid cytopathology using only four categories improves intra- and inter-observer diagnostic agreement and provides non-overlapping estimates of malignancy risks
    • Epub ahead of print]
    • Walts AE, Bose S, Fan X, et al. A simplified Bethesda system for reporting thyroid cytopathology using only four categories improves intra- and inter-observer diagnostic agreement and provides non-overlapping estimates of malignancy risks. Diagn Cytopathol. 2011 [Epub ahead of print].
    • (2011) Diagn. Cytopathol.
    • Walts, A.E.1    Bose, S.2    Fan, X.3
  • 33
    • 73349103783 scopus 로고    scopus 로고
    • Thyroid fine-needle aspiration with atypia of undetermined significance: A necessary or optional category
    • Shi Y, Ding X, Klein M, et al. Thyroid fine-needle aspiration with atypia of undetermined significance: a necessary or optional category? Cancer. 2009;117:298-304.
    • (2009) Cancer , vol.117 , pp. 298-304
    • Shi, Y.1    Ding, X.2    Klein, M.3
  • 34
    • 84859997630 scopus 로고    scopus 로고
    • Comparison of 5-tiered and 6-tiered diagnostic systems for the reporting of thyroid cytopathology: A multi-institutional study
    • Epub ahead of print]
    • Bongiovanni M, Crippa S, Baloch Z, et al. Comparison of 5-tiered and 6-tiered diagnostic systems for the reporting of thyroid cytopathology: a multi-institutional study. Cancer Cytopathol. 2011 [Epub ahead of print].
    • (2011) Cancer Cytopathol.
    • Bongiovanni, M.1    Crippa, S.2    Baloch, Z.3
  • 35
    • 82655171621 scopus 로고    scopus 로고
    • Eliminating the 'atypia of undetermined significance/follicular lesion of undetermined significance' category from the bethesda system for reporting thyroid cytopathology
    • Singh RS, Wang HH. Eliminating the 'atypia of undetermined significance/follicular lesion of undetermined significance' category from the bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2011;136:896-902.
    • (2011) Am. J. Clin. Pathol. , vol.136 , pp. 896-902
    • Singh, R.S.1    Wang, H.H.2
  • 36
    • 80052898479 scopus 로고    scopus 로고
    • Minimizing the diagnosis of 'follicular lesion of undetermined significance' and identifying predictive features for neoplasia
    • Jing X, Roh MH, Knoepp SM, et al. Minimizing the diagnosis of 'follicular lesion of undetermined significance' and identifying predictive features for neoplasia. Diagn Cytopathol. 2011;39:737-742.
    • (2011) Diagn. Cytopathol. , vol.39 , pp. 737-742
    • Jing, X.1    Roh, M.H.2    Knoepp, S.M.3
  • 37
    • 83455204123 scopus 로고    scopus 로고
    • Subclassification of atypical cells of undetermined significance in direct smears of fine-needle aspirations of the thyroid: Distinct patterns and associated risk of malignancy
    • Renshaw AA. Subclassification of atypical cells of undetermined significance in direct smears of fine-needle aspirations of the thyroid: distinct patterns and associated risk of malignancy. Cancer Cytopathol. 2011;119:322-327.
    • (2011) Cancer Cytopathol. , vol.119 , pp. 322-327
    • Renshaw, A.A.1
  • 38
    • 79952199151 scopus 로고    scopus 로고
    • Diagnostic criteria and risk-adapted approach to indeterminate thyroid cytodiagnosis
    • Abele JS, Levine RA. Diagnostic criteria and risk-adapted approach to indeterminate thyroid cytodiagnosis. Cancer Cytopathol. 2010;118:415-422.
    • (2010) Cancer Cytopathol. , vol.118 , pp. 415-422
    • Abele, J.S.1    Levine, R.A.2
  • 39
    • 80053556773 scopus 로고    scopus 로고
    • Usefulness of diagnostic qualifiers for thyroid fine-needle aspirations with atypia of undetermined significance
    • VanderLaan PA, Marqusee E, Krane JF. Usefulness of diagnostic qualifiers for thyroid fine-needle aspirations with atypia of undetermined significance. Am J Clin Pathol. 2011; 136:572-577.
    • (2011) Am. J. Clin. Pathol. , vol.136 , pp. 572-577
    • VanderLaan, P.A.1    Marqusee, E.2    Krane, J.F.3
  • 40
    • 75149168796 scopus 로고    scopus 로고
    • Clinical and cytological features predictive of malignancy in thyroid follicular neoplasms
    • Lubitz CC, Faquin WC, Yang J, et al. Clinical and cytological features predictive of malignancy in thyroid follicular neoplasms. Thyroid. 2010;20:25-31.
    • (2010) Thyroid. , vol.20 , pp. 25-31
    • Lubitz, C.C.1    Faquin, W.C.2    Yang, J.3
  • 41
    • 84859964459 scopus 로고    scopus 로고
    • Can cytomorphology further stratify thyroid fine needle aspirates diagnosed as follicular lesion of undetermined significance
    • Walts AE, Bresee C, Bose S. Can cytomorphology further stratify thyroid fine needle aspirates diagnosed as follicular lesion of undetermined significance? Cytojournal. 2011;8:S66.
    • (2011) Cytojournal. , vol.8
    • Walts, A.E.1    Bresee, C.2    Bose, S.3
  • 42
    • 83455204124 scopus 로고    scopus 로고
    • Group consensus review minimizes the diagnosis of 'follicular lesion of undetermined significance' and improves cytohistologic concordance
    • Epub ahead of print]
    • Jing X, Knoepp SM, Roh MH, et al. Group consensus review minimizes the diagnosis of 'follicular lesion of undetermined significance' and improves cytohistologic concordance. Diagn Cytopathol. 2011 [Epub ahead of print].
    • (2011) Diagn. Cytopathol.
    • Jing, X.1    Knoepp, S.M.2    Roh, M.H.3
  • 43
    • 79953301552 scopus 로고    scopus 로고
    • Familial thyroid cancer: A review
    • Nose V. Familial thyroid cancer: a review. Mod Pathol. 2011;24(suppl 2):S19-S33.
    • (2011) Mod. Pathol. , vol.24 , Issue.SUPPL. 2
    • Nose, V.1
  • 45
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: One gene, Many syndromes
    • DOI 10.1002/humu.10257
    • Eng C. PTEN: one gene, many syndromes. Hum Mutat. 2003;22:183-198. (Pubitemid 37071635)
    • (2003) Human Mutation , vol.22 , Issue.3 , pp. 183-198
    • Eng, C.1
  • 46
    • 0033258497 scopus 로고    scopus 로고
    • Thyroid pathologic findings in patients with Cowden disease
    • Harach HR, Soubeyran I, Brown A, et al. Thyroid pathologic findings in patients with Cowden disease. Ann Diagn Pathol. 1999;3:331-340.
    • (1999) Ann. Diagn. Pathol. , vol.3 , pp. 331-340
    • Harach, H.R.1    Soubeyran, I.2    Brown, A.3
  • 49
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura ET, NikiforovaMN, Zhu Z, et al. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res. 2003;63:1454-1457. (Pubitemid 36373628)
    • (2003) Cancer Research , vol.63 , Issue.7 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 50
  • 53
    • 34250893789 scopus 로고    scopus 로고
    • Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: A meta-analysis
    • Lee JH, Lee ES, Kim YS. Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis. Cancer. 2007;110:38-46.
    • (2007) Cancer , vol.110 , pp. 38-46
    • Lee, J.H.1    Lee, E.S.2    Kim, Y.S.3
  • 54
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • DOI 10.1677/erc.1.0978
    • Xing M. BRAF mutation in thyroid cancer. Endocr Relat Cancer. 2005;12:245-262. (Pubitemid 40896444)
    • (2005) Endocrine-Related Cancer , vol.12 , Issue.2 , pp. 245-262
    • Xing, M.1
  • 55
    • 77955351326 scopus 로고    scopus 로고
    • BRAFV600E mutation analysis in fine-needle aspiration cytology specimens for evaluation of thyroid nodule: A large series in a BRAFV600 E-prevalent population
    • Kim SW, Lee JI, Kim JW, et al. BRAFV600E mutation analysis in fine-needle aspiration cytology specimens for evaluation of thyroid nodule: a large series in a BRAFV600 E-prevalent population. J Clin Endocrinol Metab. 2010;95: 3693-3700.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 3693-3700
    • Kim, S.W.1    Lee, J.I.2    Kim, J.W.3
  • 56
    • 79952309163 scopus 로고    scopus 로고
    • Surgical results of thyroid nodules according to a management guideline based on the BRAF(V600E) mutation status
    • Kim SK, Hwang TS, Yoo YB, et al. Surgical results of thyroid nodules according to a management guideline based on the BRAF(V600E) mutation status. J Clin Endocrinol Metab. 2011;96:658-664.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 658-664
    • Kim, S.K.1    Hwang, T.S.2    Yoo, Y.B.3
  • 58
    • 8144230516 scopus 로고    scopus 로고
    • BRAF mutations in anaplastic thyroid carcinoma: Implications for tumor origin, diagnosis and treatment
    • DOI 10.1038/modpathol.3800198
    • Begum S, Rosenbaum E, Henrique R, et al. BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment. Mod Pathol. 2004;17:1359-1363. (Pubitemid 39472990)
    • (2004) Modern Pathology , vol.17 , Issue.11 , pp. 1359-1363
    • Begum, S.1    Rosenbaum, E.2    Henrique, R.3    Cohen, Y.4    Sidransky, D.5    Westra, W.H.6
  • 59
    • 79959339173 scopus 로고    scopus 로고
    • Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules
    • Kim SY, Yoon J, Ko YS, et al. Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules. BMC Cancer. 2011;11:264.
    • (2011) BMC Cancer , vol.11 , pp. 264
    • Kim, S.Y.1    Yoon, J.2    Ko, Y.S.3
  • 60
    • 84856443942 scopus 로고    scopus 로고
    • The association of the BRAF(V600E) mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta-analysis
    • Epub
    • Kim TH, Park YJ, Lim JA, et al. The association of the BRAF(V600E) mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: a meta-analysis. Cancer. 2011. Epub.
    • (2011) Cancer
    • Kim, T.H.1    Park, Y.J.2    Lim, J.A.3
  • 62
    • 53749086690 scopus 로고    scopus 로고
    • BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: A 15-year median follow-up study
    • Elisei R, Ugolini C, Viola D, et al. BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study. J Clin Endocrinol Metab. 2008;93:3943-3949.
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 3943-3949
    • Elisei, R.1    Ugolini, C.2    Viola, D.3
  • 63
    • 70549098158 scopus 로고    scopus 로고
    • Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation
    • Yip L, Nikiforova MN, Carty SE, et al. Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation. Surgery. 2009;146:1215-1223.
    • (2009) Surgery , vol.146 , pp. 1215-1223
    • Yip, L.1    Nikiforova, M.N.2    Carty, S.E.3
  • 64
    • 0025022463 scopus 로고
    • PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
    • Grieco M, Santoro M, Berlingieri MT, et al. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell. 1990;60:557-563.
    • (1990) Cell , vol.60 , pp. 557-563
    • Grieco, M.1    Santoro, M.2    Berlingieri, M.T.3
  • 66
    • 0026763062 scopus 로고
    • Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype
    • Santoro M, Carlomagno F, Hay ID, et al. Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype. J Clin Invest. 1992;89:1517-1522.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1517-1522
    • Santoro, M.1    Carlomagno, F.2    Hay, I.D.3
  • 68
    • 33748742902 scopus 로고    scopus 로고
    • Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: Effects of the detection methods and genetic heterogeneity
    • DOI 10.1210/jc.2006-1006
    • Zhu Z, Ciampi R, Nikiforova MN, et al. Prevalence of RET/ PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity. J Clin Endocrinol Metab. 2006;91:3603-3610. (Pubitemid 44402144)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.9 , pp. 3603-3610
    • Zhu, Z.1    Ciampi, R.2    Nikiforova, M.N.3    Gandhi, M.4    Nikiforov, Y.E.5
  • 69
    • 0025923247 scopus 로고
    • TPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method
    • Ishizaka Y, Kobayashi S, Ushijima T, et al. Detection of retTPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method. Oncogene. 1991;6:1667-1672. (Pubitemid 21924271)
    • (1991) Oncogene , vol.6 , Issue.9 , pp. 1667-1672
    • Ishizaka, Y.1    Kobayashi, S.2    Ushijima, T.3    Hirohashi, S.4    Sugimura, T.5    Nagao, M.6
  • 71
    • 0025265096 scopus 로고
    • Presence of mutations in all three ras genes in human thyroid tumors
    • Suarez HG, du Villard JA, Severino M, et al. Presence of mutations in all three ras genes in human thyroid tumors. Oncogene. 1990;5:565-570.
    • (1990) Oncogene , vol.5 , pp. 565-570
    • Suarez, H.G.1    Du Villard, J.A.2    Severino, M.3
  • 73
    • 85047687680 scopus 로고    scopus 로고
    • Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma: An unusually high prevalence of ras mutations
    • DOI 10.1309/ND8D-9LAJ-TRCT-G6QD
    • Zhu Z, Gandhi M, Nikiforova MN, et al. Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am J Clin Pathol. 2003;120:71-77. (Pubitemid 37046372)
    • (2003) American Journal of Clinical Pathology , vol.120 , Issue.1 , pp. 71-77
    • Zhu, Z.1    Gandhi, M.2    Nikiforova, M.N.3    Fischer, A.H.4    Nikiforov, Y.E.5
  • 82
    • 0026575904 scopus 로고
    • Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland
    • Ito T, Seyama T, Mizuno T, et al. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res. 1992;52:1369-1371.
    • (1992) Cancer Res. , vol.52 , pp. 1369-1371
    • Ito, T.1    Seyama, T.2    Mizuno, T.3
  • 83
    • 0035108299 scopus 로고    scopus 로고
    • β-Catenin dysregulation in thyroid neoplasms: Down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis
    • Garcia-Rostan G, Camp RL, Herrero A, et al. Beta-catenin dysregulation in thyroid neoplasms: down-regulation, aberrant nuclear expression, and CTNNB1 exon 3 mutations are markers for aggressive tumor phenotypes and poor prognosis. Am J Pathol. 2001;158:987-996. (Pubitemid 32221790)
    • (2001) American Journal of Pathology , vol.158 , Issue.3 , pp. 987-996
    • Garcia-Rostan, G.1    Camp, R.L.2    Herrero, A.3    Carcangiu, M.L.4    Rimm, D.L.5    Tallini, G.6
  • 88
    • 50249103246 scopus 로고    scopus 로고
    • MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma
    • Chen YT, Kitabayashi N, Zhou XK, et al. MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma. Mod Pathol. 2008;21:1139-1146.
    • (2008) Mod. Pathol. , vol.21 , pp. 1139-1146
    • Chen, Y.T.1    Kitabayashi, N.2    Zhou, X.K.3
  • 93
    • 77950484599 scopus 로고    scopus 로고
    • Contribution of molecular testing to thyroid fine-needle aspiration cytology of 'follicular lesion of undetermined significance/atypia of undetermined significance
    • Ohori NP, Nikiforova MN, Schoedel KE, et al. Contribution of molecular testing to thyroid fine-needle aspiration cytology of 'follicular lesion of undetermined significance/atypia of undetermined significance'. Cancer Cytopathol. 2010;118: 17-23.
    • (2010) Cancer Cytopathol. , vol.118 , pp. 17-23
    • Ohori, N.P.1    Nikiforova, M.N.2    Schoedel, K.E.3
  • 94
    • 77749246208 scopus 로고    scopus 로고
    • Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology
    • Cantara S, Capezzone M, Marchisotta S, et al. Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology. J Clin Endocrinol Metab. 2010;95:1365-1369.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 1365-1369
    • Cantara, S.1    Capezzone, M.2    Marchisotta, S.3
  • 95
    • 66749159724 scopus 로고    scopus 로고
    • Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules
    • Nikiforov YE, Steward DL, Robinson-Smith TM, et al. Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules. J Clin Endocrinol Metab. 2009;94:2092-2098.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 2092-2098
    • Nikiforov, Y.E.1    Steward, D.L.2    Robinson-Smith, T.M.3
  • 96
    • 79953325102 scopus 로고    scopus 로고
    • Molecular analysis of thyroid tumors
    • Nikiforov YE. Molecular analysis of thyroid tumors. Mod Pathol. 2011;24(suppl 2):S34-S43.
    • (2011) Mod. Pathol. , vol.24 , Issue.SUPPL. 2
    • Nikiforov, Y.E.1
  • 98
    • 80655147350 scopus 로고    scopus 로고
    • Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: A prospective analysis of 1056 FNA samples
    • Nikiforov YE, Ohori NP, Hodak SP, et al. Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples. J Clin Endocrinol Metab. 2011;96:3390-3397.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 3390-3397
    • Nikiforov, Y.E.1    Ohori, N.P.2    Hodak, S.P.3
  • 99
    • 78649952872 scopus 로고    scopus 로고
    • BRAF(V600E) mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer
    • Discussion 1145-1146
    • O'Neill CJ, Bullock M, Chou A, et al. BRAF(V600E) mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer. Surgery. 2010;148:1139-1145. Discussion 1145-1146.
    • (2010) Surgery , vol.148 , pp. 1139-1145
    • O'Neill, C.J.1    Bullock, M.2    Chou, A.3
  • 100
    • 66349098309 scopus 로고    scopus 로고
    • Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF PIK3CA and AKT1
    • Ricarte-Filho JC, Ryder M, Chitale DA, et al. Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1. Cancer Res. 2009; 69:4885-4893.
    • (2009) Cancer Res. , vol.69 , pp. 4885-4893
    • Ricarte-Filho, J.C.1    Ryder, M.2    Chitale, D.A.3
  • 102
    • 77950920870 scopus 로고    scopus 로고
    • Prognostic utility of BRAF mutation in papillary thyroid cancer
    • Xing M. Prognostic utility of BRAF mutation in papillary thyroid cancer. Mol Cell Endocrinol. 2010;321:86-93.
    • (2010) Mol. Cell Endocrinol. , vol.321 , pp. 86-93
    • Xing, M.1
  • 103
    • 77954219743 scopus 로고    scopus 로고
    • Targeted therapy of thyroid cancer
    • Sherman SI. Targeted therapy of thyroid cancer. Biochem Pharmacol. 2010;80:592-601.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 592-601
    • Sherman, S.I.1
  • 104
    • 78650976224 scopus 로고    scopus 로고
    • The BRAF mutation is predictive of aggressive clinicopathological characteristics in papillary thyroid microcarcinoma
    • Lin KL, Wang OC, Zhang XH, et al. The BRAF mutation is predictive of aggressive clinicopathological characteristics in papillary thyroid microcarcinoma. Ann Surg Oncol. 2010;17: 3294-3300.
    • (2010) Ann. Surg. Oncol. , vol.17 , pp. 3294-3300
    • Lin, K.L.1    Wang, O.C.2    Zhang, X.H.3
  • 105
    • 73949139889 scopus 로고    scopus 로고
    • Association of BRAFV600E mutation with poor clinical prognostic factors and US features in Korean patients with papillary thyroid microcarcinoma
    • Kwak JY, Kim EK, Chung WY, et al. Association of BRAFV600E mutation with poor clinical prognostic factors and US features in Korean patients with papillary thyroid microcarcinoma. Radiology. 2009;253:854-860.
    • (2009) Radiology , vol.253 , pp. 854-860
    • Kwak, J.Y.1    Kim, E.K.2    Chung, W.Y.3
  • 106
    • 59449090715 scopus 로고    scopus 로고
    • Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma
    • Lee X, Gao M, Ji Y, et al. Analysis of differential BRAF(V600E) mutational status in high aggressive papillary thyroid microcarcinoma. Ann Surg Oncol. 2009;16:240-245.
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 240-245
    • Lee, X.1    Gao, M.2    Ji, Y.3
  • 108
    • 82955233568 scopus 로고    scopus 로고
    • Both BRAF V600E mutation and older age (>/=65 years) are associated with recurrent papillary thyroid cancer
    • Howell GM, Carty SE, Armstrong MJ, et al. Both BRAF V600E mutation and older age (>/=65 years) are associated with recurrent papillary thyroid cancer. Ann Surg Oncol. 2011;18:3566-3571.
    • (2011) Ann. Surg. Oncol. , vol.18 , pp. 3566-3571
    • Howell, G.M.1    Carty, S.E.2    Armstrong, M.J.3
  • 109
    • 84859994910 scopus 로고    scopus 로고
    • A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma
    • Epub ahead of print]
    • Niemeier LA, Kuffner Akatsu H, Song C, et al. A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma. Cancer. 2011 [Epub ahead of print].
    • (2011) Cancer.
    • Niemeier, L.A.1    Kuffner Akatsu, H.2    Song, C.3


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