Eliminating the "Atypia of Undetermined Significance/ Follicular Lesion of Undetermined Significance" category from the Bethesda system for reporting thyroid cytopathology

American Journal of Clinical Pathology

Volumn 136, Issue 6, 2011, Pages 896-902

  Singh, Remmi S ^a   Wang, Helen H ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Atypia of undetermined significance; Bethesda system for reporting thyroid cytopathology; Cytology; Follicular lesion of undetermined significance; Thyroid lesions

Indexed keywords

ADULT; ARTICLE; ASPIRATION BIOPSY; ATYPIA OF UNDETERMINED SIGNIFICANCE; BETHESDA SYSTEM; CANCER CYTODIAGNOSIS; CONTROLLED STUDY; CYTOPATHOLOGY; FEMALE; FOLLICULAR LESION OF UNDETERMINED SIGNIFICANCE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PREDICTIVE VALUE; PRIORITY JOURNAL; THYROID FOLLICULAR CARCINOMA; THYROID MEDULLARY CARCINOMA; THYROID NODULE; THYROID PAPILLARY CARCINOMA; THYROID PARAFOLLICULAR CELL; THYROIDECTOMY;

BIOPSY, FINE-NEEDLE; HUMANS; RETROSPECTIVE STUDIES; THYROID GLAND; THYROID NEOPLASMS; THYROIDECTOMY;

EID: 82655171621     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPIX52MBOKTICP     Document Type: Article

References (21)

1. Ali SZ, Cibas E. The Bethesda System for Reporting Thyroid Cytopathology. New York, NY: Springer; 2009.
2. Faquin WC, Baloch ZW. Fine-needle aspiration of follicular patterned lesions of the thyroid: diagnosis, management, and follow-up according to National Cancer Institute (NCI) recommendations. Diagn Cytopathol. 2010;38:731-739.
3. Jo VY, Stelow EB, Dustin SM, et al. Malignancy risk for fineneedle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology. Am J Clin Pathol. 2010;134:450-456.
4. Layfield LJ, Morton MJ, Cramer HM, et al. Implications of the proposed thyroid fine-needle aspiration category of "follicular lesion of undetermined significance": a five-year multi-institutional analysis. Diagn Cytopathol. 2009;37:710- 714.
5. Luu MH, Fischer AH, Pisharodi L, et al. Improved preoperative definitive diagnosis of papillary thyroid carcinoma in FNAs prepared with both ThinPrep and conventional smears compared with FNAs prepared with ThinPrep alone. Cancer Cytopathol. 2011;119:68-73.
6. Marchevsky AM, Walts AE, Bose S, et al. Evidencebased evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies. Diagn Cytopathol. 2010;38:252-259.
7. Nayar R, Ivanovic M. The indeterminate thyroid fineneedle aspiration: experience from an academic center using terminology similar to that proposed in the 2007 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. Cancer. 2009;117:195-202.
8. Renshaw AA. Should "atypical follicular cells" in thyroid fine-needle aspirates be subclassified? Cancer Cytopathol. 2010;118:186-189.
9. Shi Y, Ding X, Klein M, et al. Thyroid fine-needle aspiration with atypia of undetermined significance: a necessary or optional category? Cancer. 2009;117:298-304.
10. Somma J, Schlecht NF, Fink D, et al. Thyroid fine needle aspiration cytology: follicular lesions and the gray zone. Acta Cytol. 2010;54:123-131.
11. Theoharis CG, Schofield KM, Hammers L, et al. The Bethesda thyroid fine-needle aspiration classification system: year 1 at an academic institution. Thyroid. 2009;19:1215- 1223.
12. VanderLaan PA, Marqusee E, Krane JF. Usefulness of diagnostic qualifiers for thyroid fine-needle aspirations: with atypia of undetermined significance. Am J Clin Pathol. 2011;136:572-577.
13. Wang HH. Reporting thyroid fine-needle aspiration: literature review and a proposal. Diagn Cytopathol. 2006;34:67-76. (Pubitemid 43062709)
14. Renshaw AA. Does a repeated benign aspirate change the risk of malignancy after an initial atypical thyroid fine-needle aspiration? Am J Clin Pathol. 2010;134:788-792.
15. Elliott DD, Pitman MB, Bloom L, et al. Fine-needle aspiration biopsy of Hürthle cell lesions of the thyroid gland: a cytomorphologic study of 139 cases with statistical analysis. Cancer. 2006;108:102-109.
16. Gonzalez JL, Wang HH, Ducatman BS. Fine-needle aspiration of Hürthle cell lesions: a cytomorphologic approach to diagnosis. Am J Clin Pathol. 1993;100:231-235. (Pubitemid 23268648)
17. Renshaw AA. Hürthle cell carcinoma is a better gold standard than Hürthle cell neoplasm for fine-needle aspiration of the thyroid: defining more consistent and specific cytologic criteria. Cancer. 2002;96:261-266. (Pubitemid 35221612)
18. Wu HH, Clouse J, Ren R. Fine-needle aspiration cytology of Hürthle cell carcinoma of the thyroid. Diagn Cytopathol. 2008;36:149-154. (Pubitemid 351312128)
19. Renshaw A. An estimate of risk of malignancy for a benign diagnosis in thyroid fine-needle aspirates. Cancer Cytopathol. 2010;118:190-195.
20. Mazzaferri EL. Management of a solitary thyroid nodule. N Engl J Med. 1993;328:553-559. (Pubitemid 23053833)
21. Renshaw AA. Focal features of papillary carcinoma of the thyroid in fine-needle aspiration material are strongly associated with papillary carcinoma at resection. Am J Clin Pathol. 2002;118:208-210. (Pubitemid 44698444)