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Volumn 35, Issue 5, 2012, Pages 260-266

Localization of PKCη in cell membranes as a predictor for breast cancer response to treatment

Author keywords

Apoptosis; Breast cancer; Neoadjuvant; PKCh; Predicting response to therapy

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA;

EID: 84859997896     PISSN: 0378584X     EISSN: 14230240     Source Type: Journal    
DOI: 10.1159/000338443     Document Type: Article
Times cited : (8)

References (28)
  • 1
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • Griner EM, Kazanietz MG: Protein kinase C and other diacylglycerol effectors in cancer. Nat Rev Cancer 2007;7:281-294.
    • (2007) Nat Rev Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 2
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y: Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 1995; 9:484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 3
    • 0035413601 scopus 로고    scopus 로고
    • Protein kinase C: Structure and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
    • Newton AC: Protein kinase C: structure and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem Rev 2001;101: 2353-2364.
    • (2001) Chem Rev , vol.101 , pp. 2353-2364
    • Newton, A.C.1
  • 4
    • 0030987070 scopus 로고    scopus 로고
    • Regulation of protein kinase C
    • Newton AC: Regulation of protein kinase C. Curr Opin Cell Biol 1997;9:161-167.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 161-167
    • Newton, A.C.1
  • 5
    • 5344265130 scopus 로고    scopus 로고
    • Protein Kinase C alpha expression in normal breast, ductal carcinoma and in situ and invasive ductal carcinoma
    • Aonsworth PD, Winstanley JHR, Pearson JM, Bishop HM, Garrod DR: Protein Kinase C alpha expression in normal breast, ductal carcinoma and in situ and invasive ductal carcinoma. Eur J Cancer 2004;40:2269-2273.
    • (2004) Eur J Cancer , vol.40 , pp. 2269-2273
    • Aonsworth, P.D.1    Winstanley, J.H.R.2    Pearson, J.M.3    Bishop, H.M.4    Garrod, D.R.5
  • 6
    • 1242273836 scopus 로고    scopus 로고
    • Immunohistochemical analysis of advanced human breast carcinomas reveals downregulation of protein kinase C alpha
    • Kerfoot C, Huang W, Rotenberg SA: Immunohistochemical analysis of advanced human breast carcinomas reveals downregulation of protein kinase C alpha. J Histochem Cytochem 2004;52:419-422.
    • (2004) J Histochem Cytochem , vol.52 , pp. 419-422
    • Kerfoot, C.1    Huang, W.2    Rotenberg, S.A.3
  • 8
    • 5644271449 scopus 로고    scopus 로고
    • Protein kinase C alpha expression in breast cancer and ovarian cancer
    • Lahn M, Köhler G, Sundell K, Su C, Li S, Paterson BM, et al.: Protein kinase C alpha expression in breast cancer and ovarian cancer. Oncology 2006;67:1-10.
    • (2006) Oncology , vol.67 , pp. 1-10
    • Lahn, M.1    Köhler, G.2    Sundell, K.3    Su, C.4    Li, S.5    Paterson, B.M.6
  • 9
    • 24944563309 scopus 로고    scopus 로고
    • Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy
    • Pan Q, Bao LW, Kleer CG, Sabel MS, Griffith KA, Teknos TN, et al: Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy. Cancer Res 2005; 65:8366-8371.
    • (2005) Cancer Res , vol.65 , pp. 8366-8371
    • Pan, Q.1    Bao, L.W.2    Kleer, C.G.3    Sabel, M.S.4    Griffith, K.A.5    Teknos, T.N.6
  • 11
    • 6844258220 scopus 로고    scopus 로고
    • Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKCeta with MDR1, MRP and LRP gene expression
    • Beck J, Bohnet B, Brugger D, Bader P, Dietl J, Scheper RJ, et al.: Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKCeta with MDR1, MRP and LRP gene expression. Brit J Cancer 1998;77:87-91.
    • (1998) Brit J Cancer , vol.77 , pp. 87-91
    • Beck, J.1    Bohnet, B.2    Brugger, D.3    Bader, P.4    Dietl, J.5    Scheper, R.J.6
  • 12
    • 0031812872 scopus 로고    scopus 로고
    • Expression analysis of protein kinase C isoenzymes and multidrug resistance associated genes in ovarian cancer cells
    • Beck JF, Bohnet B, Brugger B, Dietel J, Scheper RJ: Expression analysis of protein kinase C isoenzymes and multidrug resistance associated genes in ovarian cancer cells. Anticancer Res 1998;18:701-705.
    • (1998) Anticancer Res , vol.18 , pp. 701-705
    • Beck, J.F.1    Bohnet, B.2    Brugger, B.3    Dietel, J.4    Scheper, R.J.5
  • 14
    • 0034627129 scopus 로고    scopus 로고
    • Overexpression of protein kinase C-h attenuates caspase activation and tumor necrosis factor a-induced cell death
    • Akkaraju GR, Basu A: Overexpression of protein kinase C-h attenuates caspase activation and tumor necrosis factor a-induced cell death. Biochem Biophys Res Commun 2000;279:103-107.
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 103-107
    • Akkaraju, G.R.1    Basu, A.2
  • 15
    • 0031614577 scopus 로고    scopus 로고
    • The involvement of novel protein kinase C isoenzymes in influencing sensitivity of breast cancer MCF-7 cells to tumor necrosis factor-alpha
    • Basu A: The involvement of novel protein kinase C isoenzymes in influencing sensitivity of breast cancer MCF-7 cells to tumor necrosis factor-alpha. Mol Pharmacol 1998;53:105-111.
    • (1998) Mol Pharmacol , vol.53 , pp. 105-111
    • Basu, A.1
  • 16
    • 0034698032 scopus 로고    scopus 로고
    • Phorbol 12-myristate 13-acetate induces protein kinase Ceta-specific proliferative response in astrocytic tumor cells
    • Hussaini IM, Karns LR, Vinton G, Carpenter JE, Redpath GT, Sando JJ, et al.: Phorbol 12-myristate 13-acetate induces protein kinase Ceta-specific proliferative response in astrocytic tumor cells. J Biol Chem 2000;275:22348-22354.
    • (2000) J Biol Chem , vol.275 , pp. 22348-22354
    • Hussaini, I.M.1    Karns, L.R.2    Vinton, G.3    Carpenter, J.E.4    Redpath, G.T.5    Sando, J.J.6
  • 17
    • 0036203133 scopus 로고    scopus 로고
    • Protein kinase C-eta regulates resistance to UV and gamma- irradiationinduced apoptosis in glioblastoma cells by preventing caspase-9 activation
    • Hussaini IM, Carpenter JE, Redpath GT, Sando JJ, Shaffrey ME, VandenBerg SR: Protein kinase C-eta regulates resistance to UV and gamma-irradiationinduced apoptosis in glioblastoma cells by preventing caspase-9 activation. Neuro Oncol 2002;4:9-21.
    • (2002) Neuro Oncol , vol.4 , pp. 9-21
    • Hussaini, I.M.1    Carpenter, J.E.2    Redpath, G.T.3    Sando, J.J.4    Shaffrey, M.E.5    Vandenberg, S.R.6
  • 18
    • 0037470837 scopus 로고    scopus 로고
    • The eta isoform of protein kinase C inhibits UV-induced activation of caspase 3 in normal human keratinocytes
    • Matsumura M, Tanaka N, Kuroli T, Ichihashi M, Ohba M: The eta isoform of protein kinase C inhibits UV-induced activation of caspase 3 in normal human keratinocytes. Biochem Biophys Res Commun 2003;303:350-356.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 350-356
    • Matsumura, M.1    Tanaka, N.2    Kuroli, T.3    Ichihashi, M.4    Ohba, M.5
  • 19
    • 4444314740 scopus 로고    scopus 로고
    • Down-regulation of PKCeta potentiates the cytotoxic effects of exogenous tumor necrosis factor-related apoptosis-inducing ligand in PC-3 prostate cancer cells
    • Sonnemann J, Gekeler V, Sagrauske A, Muller C, Hofmann HP, Beck JF: Down-regulation of PKCeta potentiates the cytotoxic effects of exogenous tumor necrosis factor-related apoptosis-inducing ligand in PC-3 prostate cancer cells. Mol Cancer Ther 2004;3:773-781.
    • (2004) Mol Cancer Ther , vol.3 , pp. 773-781
    • Sonnemann, J.1    Gekeler, V.2    Sagrauske, A.3    Muller, C.4    Hofmann, H.P.5    Beck, J.F.6
  • 20
    • 67651036183 scopus 로고    scopus 로고
    • PKCeta confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells
    • Rotem-Dai N, Oberkovitz G, Abu-Ghanem S, Livneh E: PKCeta confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells. Exp Cell Res 2009;315:2616-2623.
    • (2009) Exp Cell Res , vol.315 , pp. 2616-2623
    • Rotem-Dai, N.1    Oberkovitz, G.2    Abu-Ghanem, S.3    Livneh, E.4
  • 21
    • 42549135395 scopus 로고    scopus 로고
    • PKCeta expression contributes to the resistance of Hodgkin's lymphoma cell lines to apoptosis
    • Abu-Ghanem S, Oberkovitz G, Benharroch D, Gopas J, Livneh E: PKCeta expression contributes to the resistance of Hodgkin's lymphoma cell lines to apoptosis. Cancer Biol Ther 2007;6:1375-1380.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1375-1380
    • Abu-Ghanem, S.1    Oberkovitz, G.2    Benharroch, D.3    Gopas, J.4    Livneh, E.5
  • 23
    • 0026098402 scopus 로고
    • Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart
    • Bacher N, Zisman Y, Berent E, Livneh E: Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol Cell Biol 1991;11:126-133.
    • (1991) Mol Cell Biol , vol.11 , pp. 126-133
    • Bacher, N.1    Zisman, Y.2    Berent, E.3    Livneh, E.4
  • 24
    • 33646346612 scopus 로고    scopus 로고
    • PKCeta is localizes in the Golgi, ER and nuclear envelope and translocates to the nuclear envelope upon PMA activation and serum-starvation: C1b domain and the pseudosubstrate containing fragment target PKCeta to the Golgi and the nuclear envelope
    • Maissel A, Marom M, Shtutman M, Shahaf G, Livneh E: PKCeta is localizes in the Golgi, ER and nuclear envelope and translocates to the nuclear envelope upon PMA activation and serum-starvation: C1b domain and the pseudosubstrate containing fragment target PKCeta to the Golgi and the nuclear envelope. Cell Signal 2006;18:1127-1139.
    • (2006) Cell Signal , vol.18 , pp. 1127-1139
    • Maissel, A.1    Marom, M.2    Shtutman, M.3    Shahaf, G.4    Livneh, E.5
  • 25
    • 0037447935 scopus 로고    scopus 로고
    • PKCeta associates with cyclin E/Cdk2 complex in serum-starved MCF-7 and NIH-3T3 cells
    • Shtutman M, Hershko T, Maissel A, Fima E, Livneh E: PKCeta associates with cyclin E/Cdk2 complex in serum-starved MCF-7 and NIH-3T3 cells. Exp Cell Res 2003;286:22-29.
    • (2003) Exp Cell Res , vol.286 , pp. 22-29
    • Shtutman, M.1    Hershko, T.2    Maissel, A.3    Fima, E.4    Livneh, E.5
  • 26
    • 2442658767 scopus 로고    scopus 로고
    • Down-regulation of protein kinase Ceta by antisense oligonucletides sensitises A549 lung cancer cells to vincristine and paclitaxel
    • Sonnemann J, Gekeler V, Ahlbresht K, Brischwein K, Liu C, Bader P, et al.: Down-regulation of protein kinase Ceta by antisense oligonucletides sensitises A549 lung cancer cells to vincristine and paclitaxel. Cancer Lett 2004;209:177-185.
    • (2004) Cancer Lett , vol.209 , pp. 177-185
    • Sonnemann, J.1    Gekeler, V.2    Ahlbresht, K.3    Brischwein, K.4    Liu, C.5    Bader, P.6
  • 27
    • 0039791449 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes
    • Schonwasser DC, Marais RM, Marshall CJ, Parker PJ: Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol Cell Biol 1998;18:790-798.
    • (1998) Mol Cell Biol , vol.18 , pp. 790-798
    • Schonwasser, D.C.1    Marais, R.M.2    Marshall, C.J.3    Parker, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.