-
1
-
-
78650250846
-
Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product
-
Li C, Zhang L, Lin G, Zuo Z. Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. J Pharm Biomed Anal. 2011;54:750-758.
-
(2011)
J Pharm Biomed Anal.
, vol.54
, pp. 750-758
-
-
Li, C.1
Zhang, L.2
Lin, G.3
Zuo, Z.4
-
2
-
-
33846948642
-
Experimental study of therapeutic efficacy of baicalin in rats with severe acute pancreatitis
-
Zhang XP, Zhang L, He JX, et al. Experimental study of therapeutic efficacy of baicalin in rats with severe acute pancreatitis. World J Gastroenterol. 2007;13:717-724.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 717-724
-
-
Zhang, X.P.1
Zhang, L.2
He, J.X.3
-
3
-
-
70350437658
-
Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway
-
Lee H, Kang R, Hahn Y, et al. Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenesis pathway. Phytother Res. 2009;23:1615-1623.
-
(2009)
Phytother Res
, vol.23
, pp. 1615-1623
-
-
Lee, H.1
Kang, R.2
Hahn, Y.3
-
4
-
-
70449370069
-
Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet
-
Guo HX, Liu DH, Ma Y, et al. Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. Acta Pharmacol Sin. 2009;30:1505-1512.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 1505-1512
-
-
Guo, H.X.1
Liu, D.H.2
Ma, Y.3
-
5
-
-
0041672474
-
2 synthesis by Scutellaria baicalensis
-
Zhang DY, Wu J, Ye F, et al. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Cancer Res. 2003;63:4037-4043. (Pubitemid 36917924)
-
(2003)
Cancer Research
, vol.63
, Issue.14
, pp. 4037-4043
-
-
Zhang, D.Y.1
Wu, J.2
Ye, F.3
Xue, L.4
Jiang, S.5
Yi, J.6
Zhang, W.7
Wei, H.8
Sung, M.9
Wang, W.10
Li, X.11
-
6
-
-
18844437520
-
Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma
-
DOI 10.1158/1078-0432.CCR-04-1974
-
Bonham M, Posakony J, Coleman I, et al. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin Cancer Res. 2005;11:3905-3914. (Pubitemid 40685612)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.10
, pp. 3905-3914
-
-
Bonham, M.1
Posakony, J.2
Coleman, I.3
Montgomery, B.4
Simon, J.5
Nelson, P.S.6
-
8
-
-
79953029008
-
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats
-
Hou YC, Lin SP, Tsai SY, et al. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. Planta Med. 2011;77:455-460.
-
(2011)
Planta Med.
, vol.77
, pp. 455-460
-
-
Hou, Y.C.1
Lin, S.P.2
Tsai, S.Y.3
-
9
-
-
0344642935
-
Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats
-
Lai MY, Hsiu SL, Tsai SY, et al. Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. J Pharm Pharmacol. 2003;55:205-209.
-
(2003)
J Pharm Pharmacol
, vol.55
, pp. 205-209
-
-
Lai, M.Y.1
Hsiu, S.L.2
Tsai, S.Y.3
-
10
-
-
33847790184
-
Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats
-
DOI 10.1016/j.jep.2006.09.036, PII S0378874106005137
-
Lu T, Song J, Huang F, et al. Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. J Ethnopharmacol. 2007;110:412-418. (Pubitemid 46389634)
-
(2007)
Journal of Ethnopharmacology
, vol.110
, Issue.3
, pp. 412-418
-
-
Lu, T.1
Song, J.2
Huang, F.3
Deng, Y.4
Xie, L.5
Wang, G.6
Liu, X.7
-
11
-
-
0034534704
-
Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form
-
DOI 10.1211/0022357001777621
-
Akao T, Kawabata K, Yanagisawa E, et al. Baicalin, the predominant flavone glucuronide of Scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. J Pharm Pharmacol. 2000;52:1563-1568. (Pubitemid 32058657)
-
(2000)
Journal of Pharmacy and Pharmacology
, vol.52
, Issue.12
, pp. 1563-1568
-
-
Akao, T.1
Kawabata, K.2
Yanagisawa, E.3
Ishihara, K.4
Mizuhara, Y.5
Wakui, Y.6
Sakashita, Y.7
Kobashi, K.8
-
12
-
-
27644442245
-
Absorption and enterohepatic circulation of baicalin in rats
-
DOI 10.1016/j.lfs.2005.04.072, PII S0024320505007356
-
Xing J, Chen X, Zhong D. Absorption and enterohepatic circulation of baicalin in rats. Life Sci. 2005;78:140-146. (Pubitemid 41560966)
-
(2005)
Life Sciences
, vol.78
, Issue.2
, pp. 140-146
-
-
Xing, J.1
Chen, X.2
Zhong, D.3
-
13
-
-
34249297623
-
Mechanistic study on the intestinal absorption and disposition of baicalein
-
DOI 10.1016/j.ejps.2007.04.001, PII S0928098707000814
-
Zhang L, Lin G, Kovacs B, et al. Mechanistic study on the intestinal absorption and disposition of baicalein. Eur J Pharm Sci. 2007;31:221-231. (Pubitemid 46818982)
-
(2007)
European Journal of Pharmaceutical Sciences
, vol.31
, Issue.3-4
, pp. 221-231
-
-
Zhang, L.1
Lin, G.2
Kovacs, B.3
Jani, M.4
Krajcsi, P.5
Zuo, Z.6
-
14
-
-
51349086819
-
Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu-tang across human intestinal Caco-2 cell monolayers
-
Dai JY, Yang JL, Li C. Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu-tang across human intestinal Caco-2 cell monolayers. Acta Pharmacol Sin. 2008;29:1086-1093.
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 1086-1093
-
-
Dai, J.Y.1
Yang, J.L.2
Li, C.3
-
15
-
-
33947164202
-
Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats
-
Kim YH, Jeong DW, Kim YC, et al. Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats. Arch Pharm Res. 2007;30:260-265.
-
(2007)
Arch Pharm Res
, vol.30
, pp. 260-265
-
-
Kim, Y.H.1
Jeong, D.W.2
Kim, Y.C.3
-
16
-
-
84859986401
-
Down-regulation of Mcl-1 by baicalein induces apoptosis through the mitochondrial pathway in human pancreatic cancer cells
-
Chicago, IL. Pancreas. 2010 November 3-6
-
Takahashi H, Chen MC, Harris DM, et al. Down-regulation of Mcl-1 by baicalein induces apoptosis through the mitochondrial pathway in human pancreatic cancer cells. 41st Annual Meeting of the American Pancreatic Association, November 3-6, 2010, Chicago, IL. Pancreas. 2010;39:1350.
-
(2010)
41st Annual Meeting of the American Pancreatic Association
, vol.39
, pp. 1350
-
-
Takahashi, H.1
Chen, M.C.2
Harris, D.M.3
-
17
-
-
25844482543
-
A xenograft nude mouse model for perineural invasion and recurrence in pancreatic cancer
-
DOI 10.1097/01.mpa.0000175176.40045.0f
-
Eibl G, Reber HA. A xenograft nude mouse model for perineural invasion and recurrence in pancreatic cancer. Pancreas. 2005;31:258-262. (Pubitemid 41400484)
-
(2005)
Pancreas
, vol.31
, Issue.3
, pp. 258-262
-
-
Eibl, G.1
Reber, H.A.2
-
19
-
-
0032566518
-
Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity
-
DOI 10.1016/S0014-5793(98)01101-6, PII S0014579398011016
-
Day AJ, DuPont MS, Ridley S, et al. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity. FEBS Lett. 1998;436:71-75. (Pubitemid 28454609)
-
(1998)
FEBS Letters
, vol.436
, Issue.1
, pp. 71-75
-
-
Day, A.J.1
Dupont, M.S.2
Ridley, S.3
Rhodes, M.4
Rhodes, M.J.C.5
Morgan, M.R.A.6
Williamson, G.7
-
20
-
-
22144495044
-
Tissue distribution of quercetin in rats and pigs
-
de Boer VC, Dihal AA, van der Woude H, et al. Tissue distribution of quercetin in rats and pigs. J Nutr. 2005;135:1718-1725. (Pubitemid 40980724)
-
(2005)
Journal of Nutrition
, vol.135
, Issue.7
, pp. 1718-1725
-
-
De Boer, V.C.J.1
Dihal, A.A.2
Van Der Woude, H.3
Arts, I.C.W.4
Wolffram, S.5
Alink, G.M.6
Rietjens, I.M.C.M.7
Keijer, J.8
Hollman, P.C.H.9
-
21
-
-
58749114381
-
New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents wogonin, baicalein and baicalin
-
Li-Weber M. New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents wogonin, baicalein and baicalin. Cancer Treat Rev. 2009;35:57-68.
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 57-68
-
-
Li-Weber, M.1
-
22
-
-
77950850484
-
Baicalin, an emerging multi-therapeutic agent: Pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives
-
Srinivas NR. Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives. Xenobiotica. 2010;40:357-367.
-
(2010)
Xenobiotica.
, vol.40
, pp. 357-367
-
-
Srinivas, N.R.1
-
23
-
-
33748916241
-
Methylated flavonoids have greatly improved intestinal absorption and metabolic stability
-
DOI 10.1124/dmd.106.011122
-
Wen X, Walle T. Methylated flavonoids have greatly improved intestinal absorption and metabolic stability. Drug Metab Dispos. 2006;34:1786-1792. (Pubitemid 44427483)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.10
, pp. 1786-1792
-
-
Wen, X.1
Walle, T.2
-
24
-
-
30144432225
-
Glucuronidase deconjugation in inflammation
-
DOI 10.1016/S0076-6879(05)00015-7, PII S0076687905000157, 15, Phase II Conjugation Enzymes and Transport Systems
-
Shimoi K, Nakayama T. Glucuronidase deconjugation in inflammation. Methods Enzymol. 2005;400:263-272. (Pubitemid 43052426)
-
(2005)
Methods in Enzymology
, vol.400
, pp. 263-272
-
-
Shimoi, K.1
Nakayama, T.2
-
25
-
-
0037295093
-
Inhibition of human breast cancer growth by GCP™ (genistein combined polysaccharide) in xenogeneic athymic mice: Involvement of genistein biotransformation by β-glucuronidase from tumor tissues
-
DOI 10.1016/S0027-5107(02)00321-4
-
Yuan L, Wagatsuma C, Yoshida M, et al. Inhibition of human breast cancer growth by GCP (genistein combined polysaccharide) in xenogeneic athymic mice: involvement of genistein biotransformation by beta-glucuronidase from tumor tissues. Mutat Res. 2003;523-524:55-62. (Pubitemid 36293232)
-
(2003)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.523-524
, pp. 55-62
-
-
Yuan, L.1
Wagatsuma, C.2
Yoshida, M.3
Miura, T.4
Mukoda, T.5
Fujii, H.6
Sun, B.7
Kim, J.-H.8
Surh, Y.-J.9
-
26
-
-
0038205705
-
1 and β-glucuronidase synchronous detection in human pancreatic cancer
-
Yue H, Yang B, Zhang H, et al. Clinical significance of TGF- beta1 and beta-glucuronidase synchronous detection in human pancreatic cancer. Hepatobiliary Pancreat Dis Int. 2002;1:309-311. (Pubitemid 36748227)
-
(2002)
Hepatobiliary and Pancreatic Diseases International
, vol.1
, Issue.2
, pp. 309-311
-
-
Yue, H.1
Yang, B.2
Zhang, H.3
Zhu, S.-D.4
Du, X.-J.5
Feng, X.-L.6
Yu, Z.7
Xia, Y.-T.8
Yu, J.-P.9
|