-
1
-
-
0345276414
-
Bcl-2-family proteins and the role of mitochondria in apoptosis
-
Kuwana T, Newmeyer DD, (2003) Bcl-2-family proteins and the role of mitochondria in apoptosis. Current Opinion in Cell Biology 15: 691-699.
-
(2003)
Current Opinion in Cell Biology
, vol.15
, pp. 691-699
-
-
Kuwana, T.1
Newmeyer, D.D.2
-
2
-
-
0036716281
-
The Bcl2 family: regulators of the cellular life-or-death switch
-
Cory S, Adams JM, (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nature reviews Cancer 2: 647-656.
-
(2002)
Nature Reviews Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
3
-
-
75949105922
-
The BCL-2 Family Reunion
-
Chipuk J, Moldoveanu T, Llambi F, Parsons M, Green D, (2010) The BCL-2 Family Reunion. Mol Cell 37: 299-310.
-
(2010)
Mol Cell
, vol.37
, pp. 299-310
-
-
Chipuk, J.1
Moldoveanu, T.2
Llambi, F.3
Parsons, M.4
Green, D.5
-
4
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Yip KW, Reed JC, (2008) Bcl-2 family proteins and cancer. Oncogene 27: 6398-6406.
-
(2008)
Oncogene
, vol.27
, pp. 6398-6406
-
-
Yip, K.W.1
Reed, J.C.2
-
5
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J, (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
6
-
-
0032555716
-
Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X, (1998) Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors. Cell 94: 481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
8
-
-
0035853811
-
Bax Is Present as a High Molecular Weight Oligomer/Complex in the Mitochondrial Membrane of Apoptotic Cells
-
Antonsson B, Montessuit S, Sanchez B, Martinou J-C, (2001) Bax Is Present as a High Molecular Weight Oligomer/Complex in the Mitochondrial Membrane of Apoptotic Cells. The Journal of biological chemistry 276: 11615-11623.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.-C.4
-
10
-
-
33745950626
-
Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario
-
Chipuk JE, Bouchier-Hayes L, Green DR, (2006) Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell death and differentiation 13: 1396-1402.
-
(2006)
Cell Death and Differentiation
, vol.13
, pp. 1396-1402
-
-
Chipuk, J.E.1
Bouchier-Hayes, L.2
Green, D.R.3
-
11
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, et al. (2005) BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Molecular Cell 17: 525-535.
-
(2005)
Molecular Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
-
12
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, et al. (2002) Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2: 183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
-
13
-
-
77949897877
-
Molecular Details of Bax Activation, Oligomerization, and Membrane Insertion
-
Bleicken S, Classen M, Padmavathi PVL, Ishikawa T, Zeth K, et al. (2010) Molecular Details of Bax Activation, Oligomerization, and Membrane Insertion. Journal of Biological Chemistry 285: 6636-6647.
-
(2010)
Journal of Biological Chemistry
, vol.285
, pp. 6636-6647
-
-
Bleicken, S.1
Classen, M.2
Padmavathi, P.V.L.3
Ishikawa, T.4
Zeth, K.5
-
14
-
-
57149135309
-
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
-
Lovell JF, Billen LP, Bindner S, Shamas-Din A, Fradin C, et al. (2008) Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell 135: 1074-1084.
-
(2008)
Cell
, vol.135
, pp. 1074-1084
-
-
Lovell, J.F.1
Billen, L.P.2
Bindner, S.3
Shamas-Din, A.4
Fradin, C.5
-
15
-
-
0038832563
-
A Novel BH3-like Domain in BID Is Required for Intramolecular Interaction and Autoinhibition of Pro-apoptotic Activity
-
Tan KO, Tan KML, Yu VC, (1999) A Novel BH3-like Domain in BID Is Required for Intramolecular Interaction and Autoinhibition of Pro-apoptotic Activity. J Biol Chem 274: 23687-23690.
-
(1999)
J Biol Chem
, vol.274
, pp. 23687-23690
-
-
Tan, K.O.1
Tan, K.M.L.2
Yu, V.C.3
-
16
-
-
0034725630
-
The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment
-
Kudla G, Montessuit S, Eskes R, Berrier C, Martinou J-C, et al. (2000) The Destabilization of Lipid Membranes Induced by the C-terminal Fragment of Caspase 8-cleaved Bid Is Inhibited by the N-terminal Fragment. J Biol Chem 275: 22713-22718.
-
(2000)
J Biol Chem
, vol.275
, pp. 22713-22718
-
-
Kudla, G.1
Montessuit, S.2
Eskes, R.3
Berrier, C.4
Martinou, J.-C.5
-
17
-
-
38049059937
-
Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment
-
Tait SWG, de Vries E, Maas C, Keller AM, D'Santos CS, et al. (2007) Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. The Journal of Cell Biology 179: 1453-1466.
-
(2007)
The Journal of Cell Biology
, vol.179
, pp. 1453-1466
-
-
Tait, S.W.G.1
de Vries, E.2
Maas, C.3
Keller, A.M.4
D'Santos, C.S.5
-
19
-
-
0033713002
-
Structure of Bax: Coregulation of Dimer Formation and Intracellular Localization
-
Suzuki M, Youle RJ, Tjandra N, (2000) Structure of Bax: Coregulation of Dimer Formation and Intracellular Localization. Cell 103: 645-654.
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
20
-
-
0030614915
-
Structure of Bcl-xL-Bak Peptide Complex: Recognition Between Regulators of Apoptosis
-
Sattler M, Liang H, Nettesheim D, Meadows RP, Harlan JE, et al. (1997) Structure of Bcl-xL-Bak Peptide Complex: Recognition Between Regulators of Apoptosis. Science 275: 983-986.
-
(1997)
Science
, vol.275
, pp. 983-986
-
-
Sattler, M.1
Liang, H.2
Nettesheim, D.3
Meadows, R.P.4
Harlan, J.E.5
-
21
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, et al. (1996) X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 381: 335-341.
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
-
22
-
-
0033525749
-
Solution Structure of the Proapoptotic Molecule BID: A Structural Basis for Apoptotic Agonists and Antagonists
-
McDonnell JM, Fushman D, Milliman CL, Korsmeyer SJ, Cowburn D, (1999) Solution Structure of the Proapoptotic Molecule BID: A Structural Basis for Apoptotic Agonists and Antagonists. Cell 96: 625-634.
-
(1999)
Cell
, vol.96
, pp. 625-634
-
-
McDonnell, J.M.1
Fushman, D.2
Milliman, C.L.3
Korsmeyer, S.J.4
Cowburn, D.5
-
23
-
-
0033525591
-
Solution structure of BID, an intracellular amplifier of apoptotic signaling
-
Chou JJ, Li H, Salvesen GS, Yuan J, Wagner G, (1999) Solution structure of BID, an intracellular amplifier of apoptotic signaling. Cell 96: 615-624.
-
(1999)
Cell
, vol.96
, pp. 615-624
-
-
Chou, J.J.1
Li, H.2
Salvesen, G.S.3
Yuan, J.4
Wagner, G.5
-
24
-
-
33845486323
-
Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets
-
Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, et al. (2006) Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets. Cell Death Differ 14: 128-136.
-
(2006)
Cell Death Differ
, vol.14
, pp. 128-136
-
-
Hinds, M.G.1
Smits, C.2
Fredericks-Short, R.3
Risk, J.M.4
Bailey, M.5
-
25
-
-
21844464054
-
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
-
Annis MG, Soucie EL, Dlugosz PJ, Cruz-Aguado JA, Penn LZ, et al. (2005) Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis. The EMBO journal 24: 2096-2103.
-
(2005)
The EMBO Journal
, vol.24
, pp. 2096-2103
-
-
Annis, M.G.1
Soucie, E.L.2
Dlugosz, P.J.3
Cruz-Aguado, J.A.4
Penn, L.Z.5
-
26
-
-
4644362829
-
Membrane-Insertion Fragments of Bcl-xl, Bax, and Bid
-
Garcia-Saez AJ, Mingarro I, Perez-Paya E, Salgado J, (2004) Membrane-Insertion Fragments of Bcl-xl, Bax, and Bid. Biochemistry 43: 10930-10943.
-
(2004)
Biochemistry
, vol.43
, pp. 10930-10943
-
-
Garcia-Saez, A.J.1
Mingarro, I.2
Perez-Paya, E.3
Salgado, J.4
-
27
-
-
70449941949
-
Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their ±6 Helices
-
Dewson G, Kratina T, Czabotar P, Day CL, Adams JM, et al. (2009) Bak Activation for Apoptosis Involves Oligomerization of Dimers via Their ±6 Helices. Molecular Cell 36: 696-703.
-
(2009)
Molecular Cell
, vol.36
, pp. 696-703
-
-
Dewson, G.1
Kratina, T.2
Czabotar, P.3
Day, C.L.4
Adams, J.M.5
-
28
-
-
77956523192
-
-
Conformational Changes in BAK, a Pore-forming Proapoptotic Bcl-2 Family Member, upon Membrane Insertion and Direct Evidence for the Existence of BH3-BH3 Contact Interface in BAK Homo-oligomers
-
Oh KJ, Singh P, Lee K, Foss K, Lee S, et al. pp. 28924-28937 Conformational Changes in BAK, a Pore-forming Proapoptotic Bcl-2 Family Member, upon Membrane Insertion and Direct Evidence for the Existence of BH3-BH3 Contact Interface in BAK Homo-oligomers.
-
-
-
Oh, K.J.1
Singh, P.2
Lee, K.3
Foss, K.4
Lee, S.5
-
29
-
-
12844266796
-
Conformational Changes in BID, a Pro-apoptotic BCL-2 Family Member, upon Membrane Binding: A SITE-DIRECTED SPIN LABELING STUDY
-
Oh KJ, Barbuto S, Meyer N, Kim R-S, Collier RJ, Korsmeyer SJ, (2005) Conformational Changes in BID, a Pro-apoptotic BCL-2 Family Member, upon Membrane Binding: A SITE-DIRECTED SPIN LABELING STUDY. J Biol Chem 280: 753-763.
-
(2005)
J Biol Chem
, vol.280
, pp. 753-763
-
-
Oh, K.J.1
Barbuto, S.2
Meyer, N.3
Kim, R.-S.4
Collier, R.J.5
Korsmeyer, S.J.6
-
30
-
-
3142713275
-
Conformation of Membrane-associated Proapoptotic tBid
-
F
-
Gong X-NC, Franzin J, Zhai C, Reed D, Marassi JC, F, (2004) Conformation of Membrane-associated Proapoptotic tBid. J Biol Chem 279: 28954-28960.
-
(2004)
J Biol Chem
, vol.279
, pp. 28954-28960
-
-
Gong, X.-N.C.1
Franzin, J.2
Zhai, C.3
Reed, D.4
Marassi, J.C.5
-
31
-
-
45849112182
-
Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax
-
Billen LP, Kokoski CL, Lovell JF, Leber B, Andrews DW, (2008) Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax. PLoS Biol 6: e147.
-
(2008)
PLoS Biol
, vol.6
-
-
Billen, L.P.1
Kokoski, C.L.2
Lovell, J.F.3
Leber, B.4
Andrews, D.W.5
-
32
-
-
70350768995
-
Membrane promotes tBID interaction with BCLXL
-
Garcia-Saez AJ, Ries J, Orzaez M, Perez-Paya E, Schwille P, (2009) Membrane promotes tBID interaction with BCLXL. Nature structural & molecular biology 16: 1178-1185.
-
(2009)
Nature Structural & Molecular Biology
, vol.16
, pp. 1178-1185
-
-
Garcia-Saez, A.J.1
Ries, J.2
Orzaez, M.3
Perez-Paya, E.4
Schwille, P.5
-
33
-
-
1842332735
-
Bcl-xL forms an ion channel in synthetic lipid membranes
-
Minn AJ, Velez P, Schendel SL, Liang H, Muchmore SW, et al. (1997) Bcl-xL forms an ion channel in synthetic lipid membranes. Nature 385: 353-357.
-
(1997)
Nature
, vol.385
, pp. 353-357
-
-
Minn, A.J.1
Velez, P.2
Schendel, S.L.3
Liang, H.4
Muchmore, S.W.5
-
34
-
-
63949086330
-
Conformational changes and protein stability of the pro-apoptotic protein Bax
-
Bleicken S, Zeth K, (2009) Conformational changes and protein stability of the pro-apoptotic protein Bax. Journal of bioenergetics and biomembranes 41: 29-40.
-
(2009)
Journal of Bioenergetics and Biomembranes
, vol.41
, pp. 29-40
-
-
Bleicken, S.1
Zeth, K.2
-
35
-
-
79956121914
-
Long-Range Distance Measurements on Nucleic Acids in Cells by Pulsed EPR Spectroscopy
-
Krstić I, Hänsel R, Romainczyk O, Engels JW, Dötsch V, et al. (2011) Long-Range Distance Measurements on Nucleic Acids in Cells by Pulsed EPR Spectroscopy. Angewandte Chemie International Edition 50: 5070-5074.
-
(2011)
Angewandte Chemie International Edition
, vol.50
, pp. 5070-5074
-
-
Krstić, I.1
Hänsel, R.2
Romainczyk, O.3
Engels, J.W.4
Dötsch, V.5
-
36
-
-
80053246250
-
Evaluation of spin labels for in-cell EPR by analysis of nitroxide reduction in cell extract of Xenopus laevis oocytes
-
Azarkh M, Okle O, Eyring P, Dietrich DR, Drescher M, (2011) Evaluation of spin labels for in-cell EPR by analysis of nitroxide reduction in cell extract of Xenopus laevis oocytes. Journal of Magnetic Resonance 212: 450-454.
-
(2011)
Journal of Magnetic Resonance
, vol.212
, pp. 450-454
-
-
Azarkh, M.1
Okle, O.2
Eyring, P.3
Dietrich, D.R.4
Drescher, M.5
-
37
-
-
77953121576
-
MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria
-
Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, et al. (2010) MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nature Cell Biology 12: 553-562.
-
(2010)
Nature Cell Biology
, vol.12
, pp. 553-562
-
-
Zaltsman, Y.1
Shachnai, L.2
Yivgi-Ohana, N.3
Schwarz, M.4
Maryanovich, M.5
-
38
-
-
77956634444
-
Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
-
Montessuit S, Somasekharan SP, Terrones O, Lucken-Ardjomande S, Herzig S, et al. (2010) Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization. Cell 142: 889-901.
-
(2010)
Cell
, vol.142
, pp. 889-901
-
-
Montessuit, S.1
Somasekharan, S.P.2
Terrones, O.3
Lucken-Ardjomande, S.4
Herzig, S.5
-
39
-
-
0037023739
-
tBID Homooligomerizes in the Mitochondrial Membrane to Induce Apoptosis
-
Grinberg M, Sarig R, Zaltsman Y, Frumkin D, Grammatikakis N, et al. (2002) tBID Homooligomerizes in the Mitochondrial Membrane to Induce Apoptosis. J Biol Chem 277: 12237-12245.
-
(2002)
J Biol Chem
, vol.277
, pp. 12237-12245
-
-
Grinberg, M.1
Sarig, R.2
Zaltsman, Y.3
Frumkin, D.4
Grammatikakis, N.5
-
40
-
-
70349172938
-
Apoptosis and glutathione: beyond an antioxidant
-
Franco R, Cidlowski JA, (2009) Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 16: 1303-1314.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1303-1314
-
-
Franco, R.1
Cidlowski, J.A.2
-
41
-
-
0034468736
-
Role of reactive oxygen species (ROS) in apoptosis induction
-
Simon H-U, Haj-Yehia A, Levi-Schaffer F, (2000) Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 5: 415-418.
-
(2000)
Apoptosis
, vol.5
, pp. 415-418
-
-
Simon, H.-U.1
Haj-Yehia, A.2
Levi-Schaffer, F.3
-
42
-
-
0034306169
-
Cardiolipin provides specificity for targeting of tBid to mitochondria
-
Lutter M, Fang M, Luo X, Nishijima M, Xie X, et al. (2000) Cardiolipin provides specificity for targeting of tBid to mitochondria. Nature cell biology 2: 754-761.
-
(2000)
Nature Cell Biology
, vol.2
, pp. 754-761
-
-
Lutter, M.1
Fang, M.2
Luo, X.3
Nishijima, M.4
Xie, X.5
-
43
-
-
79953276389
-
Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
-
Edlich F, Banerjee S, Suzuki M, Cleland Megan M, Arnoult D, et al. (2011) Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol. Cell 145: 104-116.
-
(2011)
Cell
, vol.145
, pp. 104-116
-
-
Edlich, F.1
Banerjee, S.2
Suzuki, M.3
Cleland Megan, M.4
Arnoult, D.5
-
44
-
-
0033535350
-
Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis
-
Desagher S, Osen-Sand A, Nichols A, Eskes R, Montessuit S, et al. (1999) Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis. The Journal of cell biology 144: 891-901.
-
(1999)
The Journal of Cell Biology
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
-
45
-
-
77957010110
-
Isolation of liver or kidney mitochondria
-
In: Ronald W, Estabrook MEP, editors, Academic Press
-
Johnson D, Lardy H, (1967) Isolation of liver or kidney mitochondria. In: Ronald W, Estabrook MEP, editors. Methods in Enzymology Academic Press pp. 94-96.
-
(1967)
Methods in Enzymology
, pp. 94-96
-
-
Johnson, D.1
Lardy, H.2
-
46
-
-
0001742157
-
Microdetermination of Phosphorus
-
Nakamura GR, (1952) Microdetermination of Phosphorus. Analytical Chemistry 24: 1372-1372.
-
(1952)
Analytical Chemistry
, vol.24
, pp. 1372
-
-
Nakamura, G.R.1
-
47
-
-
0026530383
-
Quantitative analysis of protein far UV circular dichroism spectra by neural networks
-
Bohm G, Muhr R, Jaenicke R, (1992) Quantitative analysis of protein far UV circular dichroism spectra by neural networks. Protein Eng 5: 191-195.
-
(1992)
Protein Eng
, vol.5
, pp. 191-195
-
-
Bohm, G.1
Muhr, R.2
Jaenicke, R.3
-
48
-
-
0034132251
-
Dead-time free measurement of dipole-dipole interactions between electron spins
-
Pannier M, Veit S, Godt A, Jeschke G, Spiess HW, (2000) Dead-time free measurement of dipole-dipole interactions between electron spins. Journal of Magnetic Resonance 142: 331-340.
-
(2000)
Journal of Magnetic Resonance
, vol.142
, pp. 331-340
-
-
Pannier, M.1
Veit, S.2
Godt, A.3
Jeschke, G.4
Spiess, H.W.5
-
49
-
-
33846344623
-
DeerAnalysis2006 - a comprehensive software package for analyzing pulsed ELDOR data
-
Jeschke G, Chechik V, Ionita P, Godt A, Zimmermann H, et al. (2006) DeerAnalysis2006- a comprehensive software package for analyzing pulsed ELDOR data. Applied Magnetic Resonance 30: 473-498.
-
(2006)
Applied Magnetic Resonance
, vol.30
, pp. 473-498
-
-
Jeschke, G.1
Chechik, V.2
Ionita, P.3
Godt, A.4
Zimmermann, H.5
|