Genome plasticity of BCG and impact on vaccine efficacy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 13, 2007, Pages 5596-5601

  Brosch, Roland ^a   Gordon, Stephen V ^b   Garnier, Thierry ^a   Eiglmeier, Karin ^a   Frigui, Wafa ^a   Valenti, Philippe ^a,e   Dos Santos, Sandrine ^a   Duthoy, Stéphanie ^a   Lacroix, Céline ^a   Garcia Pelayo, Carmen ^b   Inwald, Jacqueline K ^b   Golby, Paul ^b   Garcia, Javier Nuñez ^b   Hewinson, R Glyn ^b   Behr, Marcel A ^c   Quail, Michael A ^d   Churcher, Carol ^d   Barrell, Bart G ^d   Parkhill, Julian ^d   Cole, Stewart T ^a  

^a INSTITUT PASTEUR   (France)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e Centre de Biologie du Developpement Toulouse   (France)

Author keywords

Glycerol metabolism; Live vaccines; Tandem duplications; Tuberculosis

Indexed keywords

BCG VACCINE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; PROTEIN CRP; PROTEIN PHOR; SIGMA FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTOME; UNCLASSIFIED DRUG; MESSENGER RNA;

ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL GENOME; GLPD2 GENE; IMMUNOGENICITY; MYCOBACTERIUM BOVIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; GENETICS; GENOME; GENOMICS; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PHENOTYPE; PHYLOGENY; TUBERCULOSIS;

MYCOBACTERIUM BOVIS BCG;

BCG VACCINE; EVOLUTION, MOLECULAR; GENOME; GENOME, BACTERIAL; GENOMICS; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM BOVIS; PHENOTYPE; PHYLOGENY; RNA, MESSENGER; TUBERCULOSIS; TUBERCULOSIS VACCINES;

EID: 34248402030     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700869104     Document Type: Article

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