Effect of pigment epithelium-derived factor on glutamate uptake in retinal müller cells under high-glucose conditions

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 2, 2012, Pages 1023-1032

  Xie, Bing ^a   Jiao, Qin ^a   Cheng, Yu ^a   Zhong, Yisheng ^a   Shen, Xi ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; GLUCOSE; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; MESSENGER RNA; PIGMENT EPITHELIUM DERIVED FACTOR; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; EXCITATORY AMINO ACID TRANSPORTER 1; EYE PROTEIN; NERVE GROWTH FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; POTASSIUM INWARDLY RECTIFYING CHANNEL, SUBFAMILY J, MEMBER 10; POTASSIUM INWARDLY-RECTIFYING CHANNEL, SUBFAMILY J, MEMBER 10; SERINE PROTEINASE INHIBITOR; SLC1A3 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; IMMUNOCYTOCHEMISTRY; MICROSCOPY; MUELLER CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; DIABETIC RETINOPATHY; DISEASE MODEL; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINA; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID TRANSPORTER 1; EYE PROTEINS; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; NERVE GROWTH FACTORS; OXIDATIVE STRESS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RETINA; SERPINS;

EID: 84859968481     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8695     Document Type: Article

References (47)

1. Lieth E, Gardner TW, Barber AJ, Antonetti DA. Retinal neurodegeneration: early pathology in diabetes. Clin Exp Ophthalmol. 2000;28:3-8.
2. Do carmo A, Ramos P, Reis A, Proença R, Cunha-vaz JG. Breakdown of the inner and outer blood retinal barrier in streptozotocininduced diabetes. Exp Eye Res. 1998;67:569-575.
3. Miyamoto K, Khosrof S, Bursell SE, et al. Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition. Proc Natl Acad Sci U S A. 1999;96:10836-10841.
4. Mizutani M, Gerhardinger C, Lorenzi M. Müller cell changes in human diabetic retinopathy. Diabetes. 1998;47:445-449.
5. Lieth E, Barber AJ, Xu B, et al. Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group. Diabetes. 1998;47:815-820.
6. Barber AJ, Antonetti DA, Gardner TW. Altered expression of retinal occluding and glial fibrillary acidic protein in experimental diabetes. Invest Ophthalmol Vis Sci. 2000;41:3561-3568.
7. Li Q, Puro DG. Diabetes-induced dysfunction of the glutamate transporter in retinal Müller cells. Invest Ophthalmol Vis Sci. 2002;43:3109-3116.
8. Terasaki H, Hirose H, Miyake Y. S-cone pathway sensitivity in diabetes measured with threshold versus intensity curves on flashed backgrounds. Invest Ophthalmol Vis Sci. 1996;37:680-684.
9. Della Sala S, Bertoni G, Somazzi L, Stubbe F, Wilkins AJ. Impaired contrast sensitivity in diabetic patients with and without retinopathy: a new technique for rapid assessment. Br J Ophthalmol. 1985;69:136-142.
10. Bresnick GH, Palta M. Oscillatory potential amplitudes: relation to severity of diabetic retinopathy. Arch Ophthalmol. 1987;105:929-933.
11. Juen S, Kieselbach GF. Electrophysiological changes in juvenile diabetics without retinopathy. Arch Ophthalmol. 1990;108:372-375.
12. Newman E, Reichenbach A. The Müller cell: a functional element of the retina. Trends Neurosci. 1990;19:307-311.
13. Ward MM, Jobling AI, Kalloniatis M, Fletcher EL. Glutamate uptake in retinal glial cells during diabetes. Diabetologia. 2005;48:351-360.
14. Vorwerk CK, Naskar R, Schuettauf F, et al. Depression of retinal glutamate transporter function leads to elevated intravitreal glutamate levels and ganglion cell death. Invest Ophthalmol Vis Sci. 2000;41:3615-3621.
15. Gerhardinger C, Costa MB, Coulombe MC, Toth I, Hoehn T, Grosu P. Expression of acute-phase response proteins in retinal Müller cells in diabetes. Invest Ophthalmol Vis Sci. 2005;46:349-357.
16. Shaked I, Ben-Dror I, Vardimon L. Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina. J Neurochem. 2002;83:574-580.
17. Ambati J, Chalam KV, Chawla DK, et al. Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol. 1997;115:1161-1166.
18. +-dependent glutamate transport into acutely isolated Müller glial cells from guinea pig retina. Pflugers Arch. 1994;429:140-142.
19. Pannicke T, Fischer W, Biedermann B, et al. P. 2X7 receptors in Müller glial cells from the human retina. J Neurosci. 2000;20: 5965-5972.
20. Pannicke T, Iandiev I, Uckermann O, et al. A potassium channellinked mechanism of glial cell swelling in the postischemic retina. Mol Cell Neurosci. 2004;26:493-502.
21. Francke M, Faude F, Pannicke T, et al. Electrophysiology of rabbit Müller (glial) cells in experimental retinal detachment and PVR. Invest Ophthalmol Vis. Sci. 42:1072-1079, 2001.
22. Napper GA, Pianta MJ, Kalloniatis M. Reduced glutamate uptake by retinal glial cells under ischemic/hypoxic conditions. Vis Neurosci. 1999;16:149-158.
23. Asano T, Shigeno T, Johshita H, Usui M, Hanamura T. A novel concept on the pathogenetic mechanism underlying ischaemic brain oedema: relevance of free radicals and eicosanoids. Acta Neurochir Suppl (Wien). 1987;41:85-96.
24. Birkle DL, Bazan NG. Light exposure stimulates arachidonic acid metabolism in intact rat retina and isolated rod outer segments. Neurochem Res. 1989;14:185-190.
25. Balboa MA, Balsinde J. Oxidative stress and arachidonic acid mobilization. Biochim Biophys Acta. 2006;1761:385-391.
26. Zhang SX, Wang JJ, Gao G, Shao C, Mott R, Ma JX. Pigment epithelium-derived factor (PEDF) is an endogenous anti inflammatory factor. FASEB J. 2006;20:323-335.
27. Mu H, Zhang XM, Liu JJ, Dong L, Feng ZL. Effect of high glucose concentration on VEGF and PEDF expression in cultured retinal Müller cells. Mol Biol Rep. 2009;36:2147-2151.
28. Lange J, Yafai Y, Reichenbach A, Wiedemann P, Eichler W. Regulation of pigment epithelium-derived factor production and release by retinal glial (Müller) cells under hypoxia. Invest Ophthalmol Vis Sci. 2008;49:5161-5167.
29. Hardwick C, Feist R, Morris R, et al. Tractional force generation by porcine Müller cells: stimulation by growth factors in human vitreous. Invest Ophthalmol Vis Sci. 1997;38:2053-2063.
30. Yamagishi S, Matsui T. Advanced glycation end products (AGEs), oxidative stress and diabetic retinopathy. Curr Pharm Biotechnol. 2011;12:362-368.
31. Banumathi E, Sheikpranbabu S, Haribalaganesh R, Gurunathan S. PEDF prevents reactive oxygen species generation and retinal endothelial cell damage at high glucose levels. Exp Eye Res. 2010; 90:89-96.
32. Zhang SX, Wang JJ, Dashti A, et al. Pigment epithelium-derived factor (PEDF) mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized-LDL. J Mol Endocrinol. 2008;41: 135-143.
33. Amano S, Yamagishi S, Inagaki Y, et al. Pigment epithelium-derived factor inhibits oxidative stress-induced apoptosis and dysfunction of cultured retinal pericytes. Microvasc Res. 2005;69:45-55.
34. Hicks D, Courtois Y. The growth and behaviour of rat retinal Muller cells in vitro, 1: an improved method for isolation and culture. Exp Eye Res. 1990;51:119-129.
35. Amaratunga A, Abraham CR, Edwards RB, Sandell JH, Schreiber BM, Fine RE. Apolipoprotein E is synthesized in the retina by Müller glial cells, secreted into the vitreous, and rapidly transported into the optic nerve by retinal ganglion cells. J Biol Chem. 1996;271:5628-5632.
36. Kusner L, Sarthy V, Mohr S. Nuclear translocation of glyceraldehyde- 3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells. Invest Ophthalmol Vis Sci. 2004; 45:1553-1561.
37. Shen X, Zhong Y, Xie B, et al. Pigment epithelium derived factor as an anti-inflammatory factor against decrease of glutamine synthetase expression in retinal Müller cells under high glucose conditions. Graefes Arch Clin Exp Ophthalmol. 2010;248:1127-1136.
38. Shono NI, Baskaeva EM. Bradford's method of determining protein: application, advantages and disadvantages (in Russian). Lab Delo. 1989;4:4-7.
39. Vik H, Holen E, Dybendal T, Elsayed S. Reestimations of the protein concentrations of birch pollen allergen extracts selected as candidates for the international standard (IS) preparation. Ann Allergy. 1989;62:87-90.
40. Gerhardinger C, McClure KD, Romeo G, Podestá F, Lorenzi M. IGF-I mRNA and signaling in the diabetic retina. Diabetes. 2001;50:175-183.
41. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:e45.
42. Fletcher EL, Phipps JA, Ward MM, Puthussery T, Wilkinson-Berka JL. Neuronal and glial cell abnormality as predictors of progression of diabetic retinopathy. Curr Pharm Des. 2007;13:2699-2712.
43. Puro DG. Diabetes-induced dysfunction of retinal Müller cells. Trans Am Ophthalmol Soc. 2002;100:339-352.
44. Ehinger B. Glial and neuronal uptake of GABA, glutamic acid, glutamine and glutathione in the rabbit retina. Exp Eye Res. 1977;25:221-234.
45. Tombran-Tink J, Johnson LV. Neuronal differentiation of retinoblastoma cells induced by medium conditioned by human RPE cells. Invest Ophthalmol Vis Sci. 1989;30:1700-1707.
46. Barnstable CJ, Tombran-Tink J. Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential. Prog Retin Eye Res. 2004;23:561-577.
47. Ogata N, Wang L, Jo N, et al. Pigment epithelium derived factor as a neuroprotective agent against ischemic retinal injury. Curr Eye Res. 2001;22:245-252.