Characterisation of innate fungal recognition in the lung

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Faro Trindade, Inês ^a   Willment, Janet A ^b   Kerrigan, Ann M ^b   Redelinghuys, Pierre ^b   Hadebe, Sabelo ^b   Reid, Delyth M ^b   Srinivasan, Naren ^a   Wainwright, Helen ^a   Lang, Dirk M ^a   Steele, Chad ^c   Brown, Gordon D ^a,b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECTIN 1; LUNG SURFACTANT; PATTERN RECOGNITION RECEPTOR; ZYMOSAN; FUNGUS ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LECTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CELL SURFACE; CONIDIUM; CONTROLLED STUDY; FEMALE; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LEUKOCYTE; LUNG FUNCTION; LUNG INFECTION; MOUSE; NONHUMAN; OPSONIZATION; PHAGOLYSOSOME; 129 MOUSE; ANIMAL; BAGG ALBINO MOUSE; CANDIDIASIS; FUNGUS SPORE; IMMUNOLOGY; LUNG ASPERGILLOSIS; LUNG LAVAGE; LUNG MYCOSIS; LYSOSOME; METABOLISM; MICROBIOLOGY; PHAGOCYTOSIS; PHAGOSOME; PHYSIOLOGY; PNEUMONIA; PROTEIN BINDING;

ANIMALS; ANTIGENS, FUNGAL; ASPERGILLUS FUMIGATUS; BRONCHOALVEOLAR LAVAGE FLUID; CANDIDA ALBICANS; CANDIDIASIS; FEMALE; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; LECTINS, C-TYPE; LUNG DISEASES, FUNGAL; LYSOSOMES; MICE; MICE, 129 STRAIN; MICE, INBRED BALB C; PHAGOCYTOSIS; PHAGOSOMES; PNEUMONIA; PROTEIN BINDING; PULMONARY ASPERGILLOSIS; PULMONARY SURFACTANTS; RECEPTORS, IMMUNOLOGIC; SPORES, FUNGAL; ZYMOSAN;

EID: 84859954516     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035675     Document Type: Article

References (56)

1. Brown GD, (2011) Innate Antifungal Immunity: The Key Role of Phagocytes. Annu Rev Immunol 29: 1-21.
2. Drummond RA, Brown GD, (2011) The role of Dectin-1 in the host defence against fungal infections. Curr Opin Microbiol.
3. Werner JL, Metz AE, Horn D, Schoeb TR, Hewitt MM, et al. (2009) Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol 182: 4938-4946.
4. Medzhitov R, (2007) Recognition of microorganisms and activation of the immune response. Nature 449: 819-826.
5. Wright JR, (2005) Immunoregulatory functions of surfactant proteins. Nat Rev Immunol 5: 58-68.
6. Chroneos ZC, Sever-Chroneos Z, Shepherd VL, (2010) Pulmonary surfactant: an immunological perspective. Cell Physiol Biochem 25: 13-26.
7. Shepherd VL, (2002) Distinct roles for lung collectins in pulmonary host defense. Am J Respir Cell Mol Biol 26: 257-260.
8. Gardai SJ, Xiao YQ, Dickinson M, Nick JA, Voelker DR, et al. (2003) By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell 115: 13-23.
9. Brown GD, (2006) Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 6: 33-43.
10. Pastva AM, Wright JR, Williams KL, (2007) Immunomodulatory roles of surfactant proteins A and D: implications in lung disease. Proc Am Thorac Soc 4: 252-257.
11. Allen MJ, Voelker DR, Mason RJ, (2001) Interactions of surfactant proteins A and D with Saccharomyces cerevisiae and Aspergillus fumigatus. Infect Immun 69: 2037-2044.
12. Lekkala M, LeVine AM, Linke MJ, Crouch EC, Linders B, et al. (2006) Effect of lung surfactant collectins on bronchoalveolar macrophage interaction with Blastomyces dermatitidis: inhibition of tumor necrosis factor alpha production by surfactant protein D. Infect Immun 74: 4549-4556.
13. Taylor PR, Tsoni SV, Willment JA, Dennehy KM, Rosas M, et al. (2007) Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol 8: 31-38.
14. Dagenais TR, Keller NP, (2009) Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin Microbiol Rev 22: 447-465.
15. Madan T, Eggleton P, Kishore U, Strong P, Aggrawal SS, et al. (1997) Binding of pulmonary surfactant proteins A and D to Aspergillus fumigatus conidia enhances phagocytosis and killing by human neutrophils and alveolar macrophages. Infect Immun 65: 3171-3179.
16. Steele C, Rapaka RR, Metz A, Pop SM, Williams DL, et al. (2005) The Beta-Glucan Receptor Dectin-1 Recognizes Specific Morphologies of Aspergillus fumigatus. PLoS Pathog 1: e42.
17. Luther K, Torosantucci A, Brakhage AA, Heesemann J, Ebel F, (2007) Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2. Cell Microbiol 9: 368-381.
18. Madan T, Reid KB, Clark H, Singh M, Nayak A, et al. (2010) Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis. Mol Immunol 47: 1923-1930.
19. Asmus MJ, Barros MD, Liang J, Chesrown SE, Hendeles L, (2001) Pulmonary function response to EDTA, an additive in nebulized bronchodilators. J Allergy Clin Immunol 107: 68-72.
20. Evans SE, (2010) Coping with Candida infections. Proc Am Thorac Soc 7: 197-203.
21. van Rozendaal BA, van Spriel AB, van De Winkel JG, Haagsman HP, (2000) Role of pulmonary surfactant protein D in innate defense against Candida albicans. J Infect Dis 182: 917-922.
22. Kelly MM, McNagny K, Williams DL, van Rooijen N, Maxwell L, et al. (2008) The lung responds to zymosan in a unique manner independent of toll-like receptors, complement, and dectin-1. Am J Respir Cell Mol Biol 38: 227-238.
23. Underhill DM, (2003) Macrophage recognition of zymosan particles. J Endotoxin Res 9: 176-180.
24. Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, et al. (2009) Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J Exp Med 206: 2037-2051.
25. Aimanianda V, Bayry J, Bozza S, Kniemeyer O, Perruccio K, et al. (2009) Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460: 1117-1121.
26. Hohl TM, Van Epps HL, Rivera A, Morgan LA, Chen PL, et al. (2005) Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific beta-Glucan Display. PLoS Pathog 1: e30.
27. Philippe B, Ibrahim-Granet O, Prevost MC, Gougerot-Pocidalo MA, Sanchez Perez M, et al. (2003) Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates. Infect Immun 71: 3034-3042.
28. Hernanz-Falcon P, Joffre O, Williams DL, Reis e Sousa C, (2009) Internalization of Dectin-1 terminates induction of inflammatory responses. Eur J Immunol 39: 507-513.
29. Ibrahim-Granet O, Philippe B, Boleti H, Boisvieux-Ulrich E, Grenet D, et al. (2003) Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages. Infect Immun 71: 891-903.
30. Thywissen A, Heinekamp T, Dahse HM, Schmaler-Ripcke J, Nietzsche S, et al. (2011) Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway. Front Microbiol 2: 96.
31. Blander JM, Medzhitov R, (2004) Regulation of phagosome maturation by signals from toll-like receptors. Science 304: 1014-1018.
32. Heinsbroek SE, Taylor PR, Martinez FO, Martinez-Pomares L, Brown GD, et al. (2008) Stage-specific sampling by pattern recognition receptors during Candida albicans phagocytosis. PLoS Pathog 4: e1000218.
33. Flannagan RS, Cosio G, Grinstein S, (2009) Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nature Reviews Microbiology 7: 355-366.
34. Dennehy KM, Ferwerda G, Faro-Trindade I, Pyz E, Willment JA, et al. (2008) Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol 38: 500-506.
35. Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Wevers B, et al. (2009) Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk. Nat Immunol.
36. Gross O, Gewies A, Finger K, Schafer M, Sparwasser T, et al. (2006) Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442: 651-656.
37. Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, et al. (2009) Differential use of CARD9 by Dectin-1 in macrophages and dendritic cells. J Immunol 182: 1146-1154.
38. Brown GD, Herre J, Williams DL, Willment JA, Marshall ASJ, et al. (2003) Dectin-1 mediates the biological effects of beta-glucan. J Exp Med 197: 1119-1124.
39. Brown GD, Taylor PR, Reid DM, Willment JA, Williams DL, et al. (2002) Dectin-1 is a major beta-glucan receptor on macrophages. J Exp Med 296: 407-412.
40. Crouch E, Wright JR, (2001) Surfactant proteins a and d and pulmonary host defense. Annu Rev Physiol 63: 521-554.
41. Haagsman HP, Hogenkamp A, van Eijk M, Veldhuizen EJ, (2008) Surfactant collectins and innate immunity. Neonatology 93: 288-294.
42. Kishore U, Reid KB, (2007) Collectins and Pentraxins. In: Brown G, Netea M, editors. Immunology of fungal infections Dordrecht Springer pp. 151-176.
43. Allen MJ, Harbeck R, Smith B, Voelker DR, Mason RJ, (1999) Binding of rat and human surfactant proteins A and D to Aspergillus fumigatus conidia. Infect Immun 67: 4563-4569.
44. Singh M, Madan T, Waters P, Sonar S, Singh SK, et al. (2009) Therapeutic effects of recombinant forms of full-length and truncated human surfactant protein D in a murine model of invasive pulmonary aspergillosis. Mol Immunol 46: 2363-2369.
45. Yamasaki S, Matsumoto M, Takeuchi O, Matsuzawa T, Ishikawa E, et al. (2009) C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. Proc Natl Acad Sci U S A 106: 1897-1902.
46. Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, et al. (2008) The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 456: 658-662.
47. Ramirez-Ortiz ZG, Specht CA, Wang JP, Lee CK, Bartholomeu DC, et al. (2008) Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA. Infect Immun 76: 2123-2129.
48. Kasperkovitz PV, Cardenas ML, Vyas JM, (2010) TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking. J Immunol 185: 7614-7622.
49. Ip WK, Sokolovska A, Charriere GM, Boyer L, Dejardin S, et al. (2010) Phagocytosis and phagosome acidification are required for pathogen processing and MyD88-dependent responses to Staphylococcus aureus. J Immunol 184: 7071-7081.
50. Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, et al. (2010) Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe 7: 38-49.
51. Maxeiner JH, Karwot R, Hausding M, Sauer KA, Scholtes P, et al. (2007) A method to enable the investigation of murine bronchial immune cells, their cytokines and mediators. Nat Protoc 2: 105-112.
52. Stokes RW, Thorson LM, Speert DP, (1998) Nonopsonic and opsonic association of Mycobacterium tuberculosis with resident alveolar macrophages is inefficient. J Immunol 160: 5514-5521.
53. Taylor PR, Brown GD, Geldhof AB, Martinez-Pomares L, Gordon S, (2003) Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo. Eur J Immunol 33: 2090-2097.
54. Tsoni SV, Kerrigan AM, Marakalala MJ, Srinivasan N, Duffield M, et al. (2009) Complement C3 plays an essential role in the control of opportunistic fungal infections. Infect Immun 77: 3679-3685.
55. Fernandez-Mora E, Polidori M, Luhrmann A, Schaible UE, Haas A, (2005) Maturation of Rhodococcus equi-containing vacuoles is arrested after completion of the early endosome stage. Traffic 6: 635-653.
56. Graham LM, Tsoni SV, Willment JA, Williams DL, Taylor PR, et al. (2006) Soluble Dectin-1 as a tool to detect beta-glucans. J Immunol Methods 314: 164-169.