Increased hepatic peroxisome proliferator-activated receptor coactivator-1α expression precedes the development of insulin resistance in offspring of rats from severe hyperglycemic mothers

Chinese Medical Journal

Volumn 125, Issue 7, 2012, Pages 1224-1229

  Ma, Jing Mei ^a   Zeng, Chan Juan ^b   Zhang, Li ^a   Shou, Chong ^a   Yang, Hui Xia ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b Shanghai Municipal Key Clinical Specialty   (China)

Author keywords

Insulin resistance; Peroxisome proliferator activated receptor coactivator 1 ; Phosphoenolpyruvate carboxykinase; Prenatal programming

Indexed keywords

CHOLESTEROL; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GENE EXPRESSION; GLUCONEOGENESIS; GROWTH RATE; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; LIPID METABOLISM; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PANCREAS ISLET BETA CELL; PROGENY; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING;

ANIMALS; FEMALE; HYPERGLYCEMIA; INSULIN RESISTANCE; LIVER; MALE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; RNA-BINDING PROTEINS; STREPTOZOCIN; TRANSCRIPTION FACTORS;

EID: 84859942983     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2012.07.007     Document Type: Article

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