The impacts of molecular motor traffic jams

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 16, 2012, Pages 5911-5912

  Ross, Jennifer L ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIMER; KINESIN; MESSENGER RNA; MOLECULAR MOTOR;

AMYOTROPHIC LATERAL SCLEROSIS; DEPOLYMERIZATION; DIMERIZATION; ENZYME BINDING; HUMAN; INTRACELLULAR TRANSPORT; MICROTUBULE; MOLECULAR DYNAMICS; NOTE; PRIORITY JOURNAL; PROTEIN FOLDING;

KINESIN; MICROTUBULES; MOLECULAR DYNAMICS SIMULATION; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84859932879     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1203542109     Document Type: Note

References (13)

1. Leduc C, et al. (2012) Molecular crowding creates traffic jams of kinesin motors on microtubules. Proc Natl Acad Sci USA 109:6100-6105.
2. Ross JL, Shuman H, Holzbaur EL, Goldman YE (2008) Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J 94:3115-3125.
3. Caviston JP, Holzbaur EL (2006) Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol 16:530-537. (Pubitemid 44444994)
4. Yildiz A, Tomishige M, Vale RD, Selvin PR (2004) Kinesin walks hand-over-hand. Science 303:676-678. (Pubitemid 38141634)
5. DeWitt MA, Chang AY, Combs PA, Yildiz A (2012) Cytoplasmic dynein moves through uncoordinated stepping of the AAA+ ring domains. Science 335:221-225.
6. Reck-Peterson SL, et al. (2006) Single-molecule analysis of dynein processivity and stepping behavior. Cell 126:335-348. (Pubitemid 44092968)
7. Ross JL, Wallace K, Shuman H, Goldman YE, Holzbaur EL (2006) Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol 8:562-570. (Pubitemid 43827348)
8. Visscher K, Schnitzer MJ, Block SM (1999) Single kinesin molecules studied with a molecular force clamp. Nature 400:184-189. (Pubitemid 29327550)
9. Mallik R, Carter BC, Lex SA, King SJ, Gross SP (2004) Cytoplasmic dynein functions as a gear in response to load. Nature 427:649-652. (Pubitemid 38248486)
10. Chevalier-Larsen E, Holzbaur EL (2006) Axonal transport and neurodegenerative disease. Biochim Biophys Acta 1762:1094-1108. (Pubitemid 44750577)
11. Gardner MK, et al. (2011) Rapid microtubule self-assembly kinetics. Cell 146:582-592.
12. Dixit R, Ross JL, Goldman YE, Holzbaur EL (2008) Differential regulation of dynein and kinesin motor proteins by tau. Science 319:1086-1089. (Pubitemid 351300789)
13. Telley IA, Bieling P, Surrey T (2009) Obstacles on the microtubule reduce the processivityof Kinesin-1 in a minimal in vitro systemand in cell extract. Biophys J 96:3341-3353.