메뉴 건너뛰기




Volumn 740, Issue , 2012, Pages 569-601

Combined computational and experimental approaches to understanding the Ca 2+ regulatory network in neurons

Author keywords

Ca 2+ handling systems; Ca 2+ microdomains; Calcium diffusion; Calcium dynamics; Computer simulations; Endogenous buffers; Experimental data; Fluorescent indicators; Heterogeneous distribution; Mathematical modeling; Monte Carlo simulation

Indexed keywords

CALCIUM ION;

EID: 84859903478     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-2888-2_26     Document Type: Article
Times cited : (3)

References (186)
  • 2
    • 33644798116 scopus 로고    scopus 로고
    • Fast functional imaging of single neurons using random-access multiphoton (RAMP) microscopy
    • Iyer V, Hoogland TM, Saggau P (2006) Fast functional imaging of single neurons using random-access multiphoton (RAMP) microscopy. J Neurophysiol 95:535-545
    • (2006) J Neurophysiol , vol.95 , pp. 535-545
    • Iyer, V.1    Hoogland, T.M.2    Saggau, P.3
  • 3
    • 77952238050 scopus 로고    scopus 로고
    • High-speed in vivo calcium imaging reveals neuronal network activity with near-millisecond precision
    • Grewe BF, Langer D, Kasper H, Kampa BM, Helmchen F (2010) High-speed in vivo calcium imaging reveals neuronal network activity with near-millisecond precision. Nat Methods 7:399-405
    • (2010) Nat Methods , vol.7 , pp. 399-405
    • Grewe, B.F.1    Langer, D.2    Kasper, H.3    Kampa, B.M.4    Helmchen, F.5
  • 4
    • 68949157066 scopus 로고    scopus 로고
    • Supraresolution imaging in brain slices using stimulated-emission depletion two-photon laser scanning microscopy
    • Ding JB, Takasaki KT, Sabatini BL (2009) Supraresolution imaging in brain slices using stimulated-emission depletion two-photon laser scanning microscopy. Neuron 63:429-437
    • (2009) Neuron , vol.63 , pp. 429-437
    • Ding, J.B.1    Takasaki, K.T.2    Sabatini, B.L.3
  • 6
    • 70450203895 scopus 로고    scopus 로고
    • Optical probing of neuronal ensemble activity
    • Grewe BF, Helmchen F (2009) Optical probing of neuronal ensemble activity. Curr Opin Neurobiol 19:520-529
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 520-529
    • Grewe, B.F.1    Helmchen, F.2
  • 10
    • 52049092533 scopus 로고    scopus 로고
    • Calcium signaling in dendrites and spines: Practical and functional considerations
    • Higley MJ, Sabatini BL (2008) Calcium signaling in dendrites and spines: practical and functional considerations. Neuron 59:902-913
    • (2008) Neuron , vol.59 , pp. 902-913
    • Higley, M.J.1    Sabatini, B.L.2
  • 12
    • 33845945973 scopus 로고    scopus 로고
    • Depolarization-induced calcium responses in sympathetic neurons: Relative contributions from Ca2+ entry, extrusion, ER/mitochondrial Ca2+ uptake and release, and Ca2+ buffering
    • Patterson M, Sneyd J, Friel DD (2007) Depolarization-induced calcium responses in sympathetic neurons: relative contributions from Ca2+ entry, extrusion, ER/mitochondrial Ca2+ uptake and release, and Ca2+ buffering. J Gen Physiol 129:29-56
    • (2007) J Gen Physiol , vol.129 , pp. 29-56
    • Patterson, M.1    Sneyd, J.2    Friel, D.D.3
  • 15
    • 34547115989 scopus 로고    scopus 로고
    • Voltage-gated calcium channels, calcium signaling, and channelopathies
    • Krebs J, Michalak M (eds) Elsevier, Amsterdam
    • Piedras-Rentería ES, Barrett CF, Cao YQ, Tsien RW (2007) Voltage-gated calcium channels, calcium signaling, and channelopathies. In: Krebs J, Michalak M (eds) Calcium: a matter of life and death. Elsevier, Amsterdam pp 127-166
    • (2007) Calcium: A Matter of Life and Death , pp. 127-166
    • Piedras-Rentería, E.S.1    Barrett, C.F.2    Cao, Y.Q.3    Tsien, R.W.4
  • 16
    • 36749035512 scopus 로고    scopus 로고
    • Plasma-membrane Ca2+ pumps: Structural diversity as the basis for functional versatility
    • Strehler EE, Filoteo AG, Penniston JT, Caride AJ (2007) Plasma-membrane Ca2+ pumps: structural diversity as the basis for functional versatility. Biochem Soc Trans 35(Pt 5):919-922
    • (2007) Biochem Soc Trans , vol.35 , Issue.PART 5 , pp. 919-922
    • Strehler, E.E.1    Filoteo, A.G.2    Penniston, J.T.3    Caride, A.J.4
  • 17
    • 33847103184 scopus 로고    scopus 로고
    • Neuronal calcium sensor proteins: Generating diversity in neuronal Ca2+ signaling
    • Burgoyne RD (2007) Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signaling. Nat Rev Neurosci 8:182-193
    • (2007) Nat Rev Neurosci , vol.8 , pp. 182-193
    • Burgoyne, R.D.1
  • 18
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • Parekh AB, Putney JW Jr (2005) Store-operated calcium channels. Physiol Rev 85:757-810
    • (2005) Physiol Rev , vol.85 , pp. 757-810
    • Parekh, A.B.1    Putney Jr., J.W.2
  • 19
    • 78049432843 scopus 로고    scopus 로고
    • Nonlinear gap junctions enable long-distance propagation of pulsating calcium waves in astrocyte networks
    • Goldberg M, De Pità M, Volman V, Berry H, Ben-Jacob E (2010) Nonlinear gap junctions enable long-distance propagation of pulsating calcium waves in astrocyte networks. PLoS Comput Biol 6:e1000909
    • (2010) PLoS Comput Biol , vol.6
    • Goldberg, M.1    De Pità, M.2    Volman, V.3    Berry, H.4    Ben-Jacob, E.5
  • 20
    • 70349642095 scopus 로고    scopus 로고
    • Spatiotemporal characteristics of calcium dynamics in astrocytes
    • Kang M, Othmer HG (2009) Spatiotemporal characteristics of calcium dynamics in astrocytes. Chaos 19:037116
    • (2009) Chaos , vol.19 , pp. 037116
    • Kang, M.1    Othmer, H.G.2
  • 21
    • 73549119222 scopus 로고    scopus 로고
    • A mathematical model of vasoreactivity in rat mesenteric arterioles. II. Conducted vasoreactivity
    • Kapela A, Nagaraja S, Tsoukias NM (2010) A mathematical model of vasoreactivity in rat mesenteric arterioles. II. Conducted vasoreactivity. Am J Physiol Heart Circ Physiol 298:H52-H65
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Kapela, A.1    Nagaraja, S.2    Tsoukias, N.M.3
  • 22
    • 0031594597 scopus 로고    scopus 로고
    • Cardiac Ca2+ dynamics: The roles of ryanodine receptor adaptation and sarcoplasmic reticulum load
    • Jafri MS, Rice JJ, Winslow RL (1998) Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys J 74:1149-1168
    • (1998) Biophys J , vol.74 , pp. 1149-1168
    • Jafri, M.S.1    Rice, J.J.2    Winslow, R.L.3
  • 23
    • 16344373083 scopus 로고    scopus 로고
    • A mathematical treatment of integrated Ca2+ dynamics within the ventricular myocyte
    • Shannon TR, Wang F, Puglisi J, Weber C, Bers DM (2004) A mathematical treatment of integrated Ca2+ dynamics within the ventricular myocyte. Biophys J 87:3351-3371
    • (2004) Biophys J , vol.87 , pp. 3351-3371
    • Shannon, T.R.1    Wang, F.2    Puglisi, J.3    Weber, C.4    Bers, D.M.5
  • 24
    • 0037380954 scopus 로고    scopus 로고
    • An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics
    • Cortassa S, Aon MA, Marban E, Winslow RL, O'Rourke B (2003) An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys J 84:2734-2755
    • (2003) Biophys J , vol.84 , pp. 2734-2755
    • Cortassa, S.1    Aon, M.A.2    Marban, E.3    Winslow, R.L.4    O'Rourke, B.5
  • 25
    • 0030767184 scopus 로고    scopus 로고
    • Minimal model of b -cell Ca2+ mitochondrial Ca2+ handling
    • Magnus G, Keizer J (1997) Minimal model of b -cell Ca2+ mitochondrial Ca2+ handling. Am J Physiol 273:C717-C733
    • (1997) Am J Physiol , vol.273
    • Magnus, G.1    Keizer, J.2
  • 26
    • 0031958402 scopus 로고    scopus 로고
    • Model of b-cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables
    • Magnus J, Keizer J (1998) Model of b -cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables. Am J Physiol 274:C1158-C1173
    • (1998) Am J Physiol , vol.274
    • Magnus, J.1    Keizer, J.2
  • 27
    • 0031968809 scopus 로고    scopus 로고
    • Model of b -cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables
    • Magnus J, Keizer J (1998) Model of b -cell mitochondrial calcium handling and electrical activity. II. Mitochondrial variables. Am J Physiol 274:C1174-C1184
    • (1998) Am J Physiol , vol.274
    • Magnus, J.1    Keizer, J.2
  • 28
    • 0035926554 scopus 로고    scopus 로고
    • Mitochondrial modulation of intracellular Ca2+ signaling
    • Fall CP, Keizer JE (2001) Mitochondrial modulation of intracellular Ca2+ signaling. J Theor Biol 210:151-165
    • (2001) J Theor Biol , vol.210 , pp. 151-165
    • Fall, C.P.1    Keizer, J.E.2
  • 30
    • 0025138491 scopus 로고
    • Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation
    • Goldbeter A, Dupont G, Berridge MG (1990) Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. Proc Natl Acad Sci USA 87:1461-1465
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1461-1465
    • Goldbeter, A.1    Dupont, G.2    Berridge, M.G.3
  • 31
    • 0027336861 scopus 로고
    • One-pool model for Ca2+ oscillations involving Ca2+ and inositol 1,4,5-trisphosphate as co-agonists for Ca2+ release
    • Dupont G, Goldbeter A (1993) One-pool model for Ca2+ oscillations involving Ca2+ and inositol 1,4,5-trisphosphate as co-agonists for Ca2+ release. Cell Calcium 14:311-322
    • (1993) Cell Calcium , vol.14 , pp. 311-322
    • Dupont, G.1    Goldbeter, A.2
  • 32
    • 0026705276 scopus 로고
    • A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration
    • De Young GW, Keizer J (1992) A single-pool inositol 1,4,5-trisphosphate- receptor-based model for agonist-stimulated oscillations in Ca2+ concentration. Proc Natl Acad Sci USA 89:9895-9899
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9895-9899
    • De Young, G.W.1    Keizer, J.2
  • 33
    • 0026611515 scopus 로고
    • Two roles of Ca2+ in agonist stimulated Ca2+ oscillations
    • Keizer J, De Young GW (1992) Two roles of Ca2+ in agonist stimulated Ca2+ oscillations. Biophys J 61:649-660
    • (1992) Biophys J , vol.61 , pp. 649-660
    • Keizer, J.1    De Young, G.W.2
  • 34
    • 0027421180 scopus 로고
    • A single-pool model for calcium oscillations and waves in the Xenopus laevis oocyte
    • Atri A, Amundson J, Clapham D, Sneyd J (1993) A single-pool model for calcium oscillations and waves in the Xenopus laevis oocyte. Biophys J 65:1727-1739
    • (1993) Biophys J , vol.65 , pp. 1727-1739
    • Atri, A.1    Amundson, J.2    Clapham, D.3    Sneyd, J.4
  • 35
    • 0028920001 scopus 로고
    • A theoretical study of cytosolic calcium waves in Xenopus oocytes
    • Jafri MS (1995) A theoretical study of cytosolic calcium waves in Xenopus oocytes. J Theor Biol 172:209-216
    • (1995) J Theor Biol , vol.172 , pp. 209-216
    • Jafri, M.S.1
  • 36
    • 0041821608 scopus 로고    scopus 로고
    • Modeling the dependence of the period of intracellular Ca2+ waves on SERCA expression
    • Falcke M, Li Y, Lechleiter JD, Camacho P (2003) Modeling the dependence of the period of intracellular Ca2+ waves on SERCA expression. Biophys J 85:1474-1481
    • (2003) Biophys J , vol.85 , pp. 1474-1481
    • Falcke, M.1    Li, Y.2    Lechleiter, J.D.3    Camacho, P.4
  • 38
    • 33745736173 scopus 로고    scopus 로고
    • A buffering SERCA pump in models of calcium dynamics
    • Higgins ER, Cannell MB, Sneyd J (2006) A buffering SERCA pump in models of calcium dynamics. Biophys J 91:151-163
    • (2006) Biophys J , vol.91 , pp. 151-163
    • Higgins, E.R.1    Cannell, M.B.2    Sneyd, J.3
  • 39
    • 0028130349 scopus 로고
    • A model of calcium dynamics in cardiac myocytes based on the kinetics of ryanodine-sensitive calcium channels
    • Tang Y, Othmer HG (1994) A model of calcium dynamics in cardiac myocytes based on the kinetics of ryanodine-sensitive calcium channels. Biophys J 67:2223-2235
    • (1994) Biophys J , vol.67 , pp. 2223-2235
    • Tang, Y.1    Othmer, H.G.2
  • 40
    • 0028876636 scopus 로고
    • A mathematical model of agonistinduced propagation of calcium waves in astrocytes
    • Roth BJ, Yagodin SV, Holtzclaw L, Russell JT (1995) A mathematical model of agonistinduced propagation of calcium waves in astrocytes. Cell Calcium 17:53-64
    • (1995) Cell Calcium , vol.17 , pp. 53-64
    • Roth, B.J.1    Yagodin, S.V.2    Holtzclaw, L.3    Russell, J.T.4
  • 41
    • 0028845999 scopus 로고
    • Mechanisms of calcium oscillations and waves: A quantitative analysis
    • Sneyd J, Keizer J, Sanderson MJ (1995) Mechanisms of calcium oscillations and waves: a quantitative analysis. FASEB J 9:1463-1472
    • (1995) FASEB J , vol.9 , pp. 1463-1472
    • Sneyd, J.1    Keizer, J.2    Sanderson, M.J.3
  • 42
    • 0029751966 scopus 로고    scopus 로고
    • Ryanodine receptor adaptation and Ca2+ -induced Ca2+ releasedependent Ca21 oscillations
    • Keizer J, Levine L (1996) Ryanodine receptor adaptation and Ca2+ -induced Ca2+ releasedependent Ca21 oscillations. Biophys J 71:3477-3487
    • (1996) Biophys J , vol.71 , pp. 3477-3487
    • Keizer, J.1    Levine, L.2
  • 43
  • 44
    • 38149002303 scopus 로고    scopus 로고
    • A bidomain threshold model of propagating calcium waves
    • Thul R, Smith GD, Coombes S (2008) A bidomain threshold model of propagating calcium waves. J Math Biol 56:435-463
    • (2008) J Math Biol , vol.56 , pp. 435-463
    • Thul, R.1    Smith, G.D.2    Coombes, S.3
  • 45
    • 77951218154 scopus 로고    scopus 로고
    • Modeling calcium waves in cardiac myocytes: Importance of calcium diffusion
    • Swietach P, Spitzer KW, Vaughan-Jones RD (2010) Modeling calcium waves in cardiac myocytes: importance of calcium diffusion. Front Biosci 15:661-680
    • (2010) Front Biosci , vol.15 , pp. 661-680
    • Swietach, P.1    Spitzer, K.W.2    Vaughan-Jones, R.D.3
  • 46
    • 0028178965 scopus 로고
    • Equations for InsP3 receptor-mediated [Ca2+] i oscillations derived from a detailed kinetic model: A Hodgkin-Huxley-like formalism
    • Li YX, Rinzel J (1994) Equations for InsP3 receptor-mediated [Ca2+] i oscillations derived from a detailed kinetic model: a Hodgkin-Huxley-like formalism. J Theor Biol 166:461-473
    • (1994) J Theor Biol , vol.166 , pp. 461-473
    • Li, Y.X.1    Rinzel, J.2
  • 47
    • 0029146149 scopus 로고
    • Spontaneous electrical and calcium oscillations in unstimulated pituitary gonadotrophs
    • Li YX, Rinzel J, Vergara L, Stojilcoví SS (1995) Spontaneous electrical and calcium oscillations in unstimulated pituitary gonadotrophs. Biophys J 69:785-795
    • (1995) Biophys J , vol.69 , pp. 785-795
    • Li, Y.X.1    Rinzel, J.2    Vergara, L.3    Stojilcoví, S.S.4
  • 48
    • 42749099322 scopus 로고    scopus 로고
    • Sparks and waves in a stochastic fire-diffuse-fire model of Ca2+ release
    • Coombes S, Timofeeva Y (2003) Sparks and waves in a stochastic fire-diffuse-fire model of Ca2+ release. Phys Rev E Stat Nonlin Soft Matter Phys 68:021915
    • (2003) Phys Rev e Stat Nonlin Soft Matter Phys , vol.68 , pp. 021915
    • Coombes, S.1    Timofeeva, Y.2
  • 49
    • 33646264319 scopus 로고    scopus 로고
    • Stochastic calcium oscillations
    • Keener JP (2006) Stochastic calcium oscillations. Math Med Biol 23:1-25
    • (2006) Math Med Biol , vol.23 , pp. 1-25
    • Keener, J.P.1
  • 50
    • 51649123544 scopus 로고    scopus 로고
    • Stochastic aspects of oscillatory Ca2+ dynamics in hepatocytes
    • Dupont G, Abou-Lovergne A, Combettes L (2008) Stochastic aspects of oscillatory Ca2+ dynamics in hepatocytes. Biophys J 95:2193-2202
    • (2008) Biophys J , vol.95 , pp. 2193-2202
    • Dupont, G.1    Abou-Lovergne, A.2    Combettes, L.3
  • 54
    • 70349633992 scopus 로고    scopus 로고
    • Introduction to focus issue: Intracellular Ca2+ dynamics a change of modelling paradigm?
    • Falcke M (2009) Introduction to focus issue: intracellular Ca2+ dynamics a change of modelling paradigm? Chaos 19:037101
    • (2009) Chaos , vol.19 , pp. 037101
    • Falcke, M.1
  • 55
    • 67449146925 scopus 로고    scopus 로고
    • Synaptic activation and membrane potential changes modulate the frequency of spontaneous elementary Ca2+ release events in the dendrites of pyramidal cells
    • Manita S, Ross WN (2009) Synaptic activation and membrane potential changes modulate the frequency of spontaneous elementary Ca2+ release events in the dendrites of pyramidal cells. J Neurosci 29:7833-7845
    • (2009) J Neurosci , vol.29 , pp. 7833-7845
    • Manita, S.1    Ross, W.N.2
  • 56
    • 0031571202 scopus 로고    scopus 로고
    • The NEURON simulation environment
    • Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-1209
    • (1997) Neural Comput , vol.9 , pp. 1179-1209
    • Hines, M.L.1    Carnevale, N.T.2
  • 58
    • 0030739712 scopus 로고    scopus 로고
    • A general computational framework for modeling cellular structure and function
    • Schaff J, Fink CC, Slepchenko B, Carson JH, Loew LM (1997) A general computational framework for modeling cellular structure and function. Biophys J 73:1135-1146
    • (1997) Biophys J , vol.73 , pp. 1135-1146
    • Schaff, J.1    Fink, C.C.2    Slepchenko, B.3    Carson, J.H.4    Loew, L.M.5
  • 60
    • 0002675486 scopus 로고    scopus 로고
    • Monte Carlo simulation of neurotransmitter release using MCell, a general simulator of cellular physiological processes
    • Bower JM (ed) Plenum Press, New York
    • Stiles JR, Bartol TM Jr, Salpeter EE, Salpeter MM (1998) Monte Carlo simulation of neurotransmitter release using MCell, a general simulator of cellular physiological processes. In: Bower JM (ed) Computational neuroscience. Plenum Press, New York, pp 279-284
    • (1998) Computational Neuroscience , pp. 279-284
    • Stiles, J.R.1    Bartol Jr., T.M.2    Salpeter, E.E.3    Salpeter, M.M.4
  • 61
    • 0014470946 scopus 로고
    • The effect of cyanide on the efflux of calcium from squid axons
    • Blaustein MP, Hodgkin AL (1969) The effect of cyanide on the efflux of calcium from squid axons. J Physiol 200:497-527
    • (1969) J Physiol , vol.200 , pp. 497-527
    • Blaustein, M.P.1    Hodgkin, A.L.2
  • 62
    • 0015153940 scopus 로고
    • Depolarization and calcium entry in squid giant axons
    • Baker PF, Hodgkin AL, Ridgway EB (1971) Depolarization and calcium entry in squid giant axons. J Physiol 218:709-755
    • (1971) J Physiol , vol.218 , pp. 709-755
    • Baker, P.F.1    Hodgkin, A.L.2    Ridgway, E.B.3
  • 63
    • 0018991826 scopus 로고
    • Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones
    • Smith SJ, Zucker RS (1980) Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones. J Physiol 300:167-196
    • (1980) J Physiol , vol.300 , pp. 167-196
    • Smith, S.J.1    Zucker, R.S.2
  • 64
    • 0003048589 scopus 로고
    • Calcium diffusion and buffering in nerve cytoplasm
    • Connor JA, Nikolakopoulou G (1982) Calcium diffusion and buffering in nerve cytoplasm. Lect Math Life Sci 15:79-101
    • (1982) Lect Math Life Sci , vol.15 , pp. 79-101
    • Connor, J.A.1    Nikolakopoulou, G.2
  • 65
    • 0025117718 scopus 로고
    • Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties
    • Sala F, Hernandez-Cruz A (1990) Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties. Biophys J 57:313-324
    • (1990) Biophys J , vol.57 , pp. 313-324
    • Sala, F.1    Hernandez-Cruz, A.2
  • 66
    • 0020956596 scopus 로고
    • Presynaptic calcium diffusion and the time courses of transmitter release and synaptic facilitation at the squid giant synapse
    • Zucker RS, Stockbridge N (1983) Presynaptic calcium diffusion and the time courses of transmitter release and synaptic facilitation at the squid giant synapse. J Neurosci 3:1263-1269
    • (1983) J Neurosci , vol.3 , pp. 1263-1269
    • Zucker, R.S.1    Stockbridge, N.2
  • 67
    • 0022381374 scopus 로고
    • Presynaptic calcium diffusion from various arrays of single channels. Implications for transmitter release and synaptic facilitation
    • Fogelson AL, Zucker RS (1985) Presynaptic calcium diffusion from various arrays of single channels. Implications for transmitter release and synaptic facilitation. Biophys J 48:1003-1017
    • (1985) Biophys J , vol.48 , pp. 1003-1017
    • Fogelson, A.L.1    Zucker, R.S.2
  • 68
    • 0021929369 scopus 로고
    • Compartmentalization of the submembrane calcium activity during calcium influx and its signifi cance in transmitter release
    • Simon SM, Llinas RR (1985) Compartmentalization of the submembrane calcium activity during calcium influx and its signifi cance in transmitter release. Biophys J 48:485-498
    • (1985) Biophys J , vol.48 , pp. 485-498
    • Simon, S.M.1    Llinas, R.R.2
  • 69
    • 0026519666 scopus 로고
    • Time course of transmitter release calculated from simulations of a calcium diffusion model
    • Yamada WM, Zucker RS (1992) Time course of transmitter release calculated from simulations of a calcium diffusion model. Biophys J 61:671-682
    • (1992) Biophys J , vol.61 , pp. 671-682
    • Yamada, W.M.1    Zucker, R.S.2
  • 70
    • 0027212083 scopus 로고
    • Spatial calcium buffering in saccular hair cells
    • Roberts WM (1993) Spatial calcium buffering in saccular hair cells. Nature 363:74-76
    • (1993) Nature , vol.363 , pp. 74-76
    • Roberts, W.M.1
  • 72
    • 0001947553 scopus 로고
    • Concentration profiles of intracellular Ca2+ in the presence of a diffusible chelator
    • Neher E (1986) Concentration profiles of intracellular Ca2+ in the presence of a diffusible chelator. Exp Brain Res Ser 14:80-96
    • (1986) Exp Brain Res ser , vol.14 , pp. 80-96
    • Neher, E.1
  • 73
    • 0026504464 scopus 로고
    • Buffering of calcium in the vicinity of a channel pore
    • Stern MD (1992) Buffering of calcium in the vicinity of a channel pore. Cell Calcium 13:183-192
    • (1992) Cell Calcium , vol.13 , pp. 183-192
    • Stern, M.D.1
  • 74
    • 0030611092 scopus 로고    scopus 로고
    • Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel
    • Naraghi M, Neher E (1997) Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel. J Neurosci 17:6961-6973
    • (1997) J Neurosci , vol.17 , pp. 6961-6973
    • Naraghi, M.1    Neher, E.2
  • 75
    • 0028363441 scopus 로고
    • Effects of rapid buffers on Ca2+ diffusion and Ca2+ oscillations
    • Wagner J, Keizer J (1994) Effects of rapid buffers on Ca2+ diffusion and Ca2+ oscillations. Biophys J 67:447-456
    • (1994) Biophys J , vol.67 , pp. 447-456
    • Wagner, J.1    Keizer, J.2
  • 76
    • 0029732847 scopus 로고    scopus 로고
    • Analytical steady-state solution to the rapid buffering approximation near an open Ca2+ channel
    • Smith GD (1996) Analytical steady-state solution to the rapid buffering approximation near an open Ca2+ channel. Biophys J 71:3064-3072
    • (1996) Biophys J , vol.71 , pp. 3064-3072
    • Smith, G.D.1
  • 77
    • 0035183189 scopus 로고    scopus 로고
    • Asymptotic analysis of buffered calcium diffusion near a point source
    • Sherman A, Smith GD, Dai L, Miura RM (2001) Asymptotic analysis of buffered calcium diffusion near a point source. SIAM J Appl Math 61:1816-1831
    • (2001) SIAM J Appl Math , vol.61 , pp. 1816-1831
    • Sherman, A.1    Smith, G.D.2    Dai, L.3    Miura, R.M.4
  • 78
    • 0037340258 scopus 로고    scopus 로고
    • Heterogeneous presynaptic release probabilities: Functional relevance for short-term plasticity
    • Trommershauser J, Schneggenburger R, Zippelius A, Neher E (2003) Heterogeneous presynaptic release probabilities: functional relevance for short-term plasticity. Biophys J 84:1563-1579
    • (2003) Biophys J , vol.84 , pp. 1563-1579
    • Trommershauser, J.1    Schneggenburger, R.2    Zippelius, A.3    Neher, E.4
  • 79
    • 38349047215 scopus 로고    scopus 로고
    • Approximate analytical time-dependent solutions to describe large-amplitude local calcium transients in the presence of buffers
    • Mironova LA, Mironov SL (2008) Approximate analytical time-dependent solutions to describe large-amplitude local calcium transients in the presence of buffers. Biophys J 94:349-358
    • (2008) Biophys J , vol.94 , pp. 349-358
    • Mironova, L.A.1    Mironov, S.L.2
  • 80
    • 0028213803 scopus 로고
    • Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells
    • Roberts WM (1994) Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells. J Neurosci 14:3246-3262
    • (1994) J Neurosci , vol.14 , pp. 3246-3262
    • Roberts, W.M.1
  • 81
    • 0030025482 scopus 로고    scopus 로고
    • Validity of the rapid buffering approximation near a point source of calcium ions
    • Smith GD, Wagner J, Keizer J (1996) Validity of the rapid buffering approximation near a point source of calcium ions. Biophys J 70:2527-2539
    • (1996) Biophys J , vol.70 , pp. 2527-2539
    • Smith, G.D.1    Wagner, J.2    Keizer, J.3
  • 82
    • 12744280681 scopus 로고    scopus 로고
    • Endogenous Ca2+ buffer concentration and Ca2+ microdomains in hippocampal neurons
    • Müller A, Kukley M, Stausberg P, Beck H, Müller W, Dietrich D (2005) Endogenous Ca2+ buffer concentration and Ca2+ microdomains in hippocampal neurons. J Neurosci 25:558-565
    • (2005) J Neurosci , vol.25 , pp. 558-565
    • Müller, A.1    Kukley, M.2    Stausberg, P.3    Beck, H.4    Müller, W.5    Dietrich, D.6
  • 83
    • 33846448744 scopus 로고    scopus 로고
    • Nanodomains of single Ca2+ channels contribute to action potential repolarization in cortical neurons
    • Müller A, Kukley M, Uebachs M, Beck H, Dietrich D (2007) Nanodomains of single Ca2+ channels contribute to action potential repolarization in cortical neurons. J Neurosci 27:483-495
    • (2007) J Neurosci , vol.27 , pp. 483-495
    • Müller, A.1    Kukley, M.2    Uebachs, M.3    Beck, H.4    Dietrich, D.5
  • 84
    • 39449110461 scopus 로고    scopus 로고
    • Nanodomain coupling between Ca2+ channels and Ca2+ sensors promotes fast and effi cient transmitter release at a cortical GABAergic synapse
    • Bucurenciu I, Kulik A, Schwaller B, Frostcher M, Jonas P (2008) Nanodomain coupling between Ca2+ channels and Ca2+ sensors promotes fast and effi cient transmitter release at a cortical GABAergic synapse. Neuron 57:536-545
    • (2008) Neuron , vol.57 , pp. 536-545
    • Bucurenciu, I.1    Kulik, A.2    Schwaller, B.3    Frostcher, M.4    Jonas, P.5
  • 85
    • 84859905871 scopus 로고    scopus 로고
    • Effects of calretinin on Ca2+ signals in cerebellar granule cells: Implications of cooperative Ca2+ binding
    • Epub ahead of print
    • Saftenku EE (2011) Effects of calretinin on Ca2+ signals in cerebellar granule cells: implications of cooperative Ca2+ binding. Cerebellum Epub ahead of print
    • (2011) Cerebellum
    • Saftenku, E.E.1
  • 86
    • 33746913130 scopus 로고    scopus 로고
    • Local signaling with molecular diffusion as a decoder of Ca2+ signals in synaptic plasticity
    • Naoki H, Sakumura Y, Ishii S (2005) Local signaling with molecular diffusion as a decoder of Ca2+ signals in synaptic plasticity. Mol Syst Biol 1:0027
    • (2005) Mol Syst Biol , vol.1 , pp. 0027
    • Naoki, H.1    Sakumura, Y.2    Ishii, S.3
  • 87
    • 0029910837 scopus 로고    scopus 로고
    • A theoretical study of calcium microdomains in turtle hair cells
    • Wu YC, Tucker T, Fettiplace R (1996) A theoretical study of calcium microdomains in turtle hair cells. Biophys J 71:2256-2275
    • (1996) Biophys J , vol.71 , pp. 2256-2275
    • Wu, Y.C.1    Tucker, T.2    Fettiplace, R.3
  • 88
    • 0030855299 scopus 로고    scopus 로고
    • Endogenous buffers limit the spread of free calcium in hair cells
    • Hall JD, Betarbet S, Jaramillo F (1997) Endogenous buffers limit the spread of free calcium in hair cells. Biophys J 73:1243-1252
    • (1997) Biophys J , vol.73 , pp. 1243-1252
    • Hall, J.D.1    Betarbet, S.2    Jaramillo, F.3
  • 89
    • 0031067017 scopus 로고    scopus 로고
    • Modeling buffered Ca2+ diffusion near the membrane: Implications for secretion in neuroendocrine cell
    • Klingauf J, Neher E (1997) Modeling buffered Ca2+ diffusion near the membrane: implications for secretion in neuroendocrine cell. Biophys J 72:674-690
    • (1997) Biophys J , vol.72 , pp. 674-690
    • Klingauf, J.1    Neher, E.2
  • 90
    • 0030001454 scopus 로고    scopus 로고
    • Synaptic structural complexity as a factor enhancing probability of calcium-mediated transmitter release
    • Cooper RL, Winslow JL, Govind CK, Atwood HL (1996) Synaptic structural complexity as a factor enhancing probability of calcium-mediated transmitter release. J Neurophysiol 75:2451-2466
    • (1996) J Neurophysiol , vol.75 , pp. 2451-2466
    • Cooper, R.L.1    Winslow, J.L.2    Govind, C.K.3    Atwood, H.L.4
  • 91
    • 0033568876 scopus 로고    scopus 로고
    • Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction
    • DiGregorio DA, Peskoff A, Vergara JL (1999) Measurement of action potential-induced presynaptic calcium domains at a cultured neuromuscular junction. J Neurosci 19:7846-7859
    • (1999) J Neurosci , vol.19 , pp. 7846-7859
    • Digregorio, D.A.1    Peskoff, A.2    Vergara, J.L.3
  • 92
    • 0034087763 scopus 로고    scopus 로고
    • Effects of mobile buffers on facilitation: Experimental and computational studies
    • Tang Y, Schlumpberger T, Kim T, Lueker M, Zucker RS (2000) Effects of mobile buffers on facilitation: experimental and computational studies. Biophys J 78:2735-2751
    • (2000) Biophys J , vol.78 , pp. 2735-2751
    • Tang, Y.1    Schlumpberger, T.2    Kim, T.3    Lueker, M.4    Zucker, R.S.5
  • 93
    • 0036708446 scopus 로고    scopus 로고
    • New and corrected simulations of synaptic facilitation
    • Matveev V, Sherman A, Zucker RS (2002) New and corrected simulations of synaptic facilitation. Biophys J 83:1368-1373
    • (2002) Biophys J , vol.83 , pp. 1368-1373
    • Matveev, V.1    Sherman, A.2    Zucker, R.S.3
  • 94
    • 2142829513 scopus 로고    scopus 로고
    • Facilitation through buffer saturation: Constraints on endogenous buffering properties
    • Matveev V, Zucker RS, Sherman A (2004) Facilitation through buffer saturation: constraints on endogenous buffering properties. Biophys J 86:2691-2709
    • (2004) Biophys J , vol.86 , pp. 2691-2709
    • Matveev, V.1    Zucker, R.S.2    Sherman, A.3
  • 95
    • 33751549509 scopus 로고    scopus 로고
    • Residual bound Ca2+ can account for the effects of Ca2+ buffers on synaptic facilitation
    • Matveev V, Bertram R, Sherman A (2006) Residual bound Ca2+ can account for the effects of Ca2+ buffers on synaptic facilitation. J Neurophysiol 96:3389-3397
    • (2006) J Neurophysiol , vol.96 , pp. 3389-3397
    • Matveev, V.1    Bertram, R.2    Sherman, A.3
  • 96
    • 2142663099 scopus 로고    scopus 로고
    • The facilitated probability of quantal secretion within an array of calcium channels of an active zone at the amphibian neuromuscular junction
    • Bennett MR, Farnell L, Gibson WG (2004) The facilitated probability of quantal secretion within an array of calcium channels of an active zone at the amphibian neuromuscular junction. Biophys J 86:2674-2690
    • (2004) Biophys J , vol.86 , pp. 2674-2690
    • Bennett, M.R.1    Farnell, L.2    Gibson, W.G.3
  • 97
    • 21544455805 scopus 로고    scopus 로고
    • Probing the endogenous Ca2+ buffers at the presynaptic terminals of the crayfish neuromuscular junction
    • Lin JW, Fu Q, Allana T (2005) Probing the endogenous Ca2+ buffers at the presynaptic terminals of the crayfish neuromuscular junction. J Neurophysiol 94:377-386
    • (2005) J Neurophysiol , vol.94 , pp. 377-386
    • Lin, J.W.1    Fu, Q.2    Allana, T.3
  • 98
    • 0036523041 scopus 로고    scopus 로고
    • Calcium secretion coupling at calyx of Held governed by nonuniform channel-vesicle topography
    • Meinrenken CJ, Borst JG, Sakmann B (2002) Calcium secretion coupling at calyx of Held governed by nonuniform channel-vesicle topography. J Neurosci 22:1648-1667
    • (2002) J Neurosci , vol.22 , pp. 1648-1667
    • Meinrenken, C.J.1    Borst, J.G.2    Sakmann, B.3
  • 99
    • 0037444568 scopus 로고    scopus 로고
    • Local routes revisited: The space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held
    • Meinrenken CJ, Borst JG, Sakmann B (2003) Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of Held. J Physiol 547(Pt 3):665-689
    • (2003) J Physiol , vol.547 , Issue.PART 3 , pp. 665-689
    • Meinrenken, C.J.1    Borst, J.G.2    Sakmann, B.3
  • 100
    • 63449094400 scopus 로고    scopus 로고
    • Mechanisms contributing to synaptic Ca2+ signals and their heterogeneity in hair cells
    • Frank T, Khimich D, Neef A, Moser T (2009) Mechanisms contributing to synaptic Ca2+ signals and their heterogeneity in hair cells. Proc Natl Acad Sci USA 106:4483-4488
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4483-4488
    • Frank, T.1    Khimich, D.2    Neef, A.3    Moser, T.4
  • 101
    • 0033915583 scopus 로고    scopus 로고
    • Calretinin modifi es presynaptic calcium signaling in frog saccular hair cells
    • Edmonds B, Reyes R, Schwaller B, Roberts WM (2000) Calretinin modifi es presynaptic calcium signaling in frog saccular hair cells. Nat Neurosci 3:786-790
    • (2000) Nat Neurosci , vol.3 , pp. 786-790
    • Edmonds, B.1    Reyes, R.2    Schwaller, B.3    Roberts, W.M.4
  • 102
    • 0033635857 scopus 로고    scopus 로고
    • Binding kinetics of calbindin-D28k determined by fl ash photolysis of caged Ca2+
    • Nagerl UV, Novo D, Mody I, Vergara JL (2000) Binding kinetics of calbindin-D28k determined by fl ash photolysis of caged Ca2+ . Biophys J 79:3009-3018
    • (2000) Biophys J , vol.79 , pp. 3009-3018
    • Nagerl, U.V.1    Novo, D.2    Mody, I.3    Vergara, J.L.4
  • 103
    • 52049125960 scopus 로고    scopus 로고
    • Control of K Ca channels by calcium nano/microdomains
    • Fakler B, Adelman JP (2008) Control of K Ca channels by calcium nano/microdomains. Neuron 59:873-881
    • (2008) Neuron , vol.59 , pp. 873-881
    • Fakler, B.1    Adelman, J.P.2
  • 104
    • 0037431131 scopus 로고    scopus 로고
    • Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals
    • Blatow M, Caputi A, Burnashev N, Monyer H, Rozov A (2003) Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron 38:79-88
    • (2003) Neuron , vol.38 , pp. 79-88
    • Blatow, M.1    Caputi, A.2    Burnashev, N.3    Monyer, H.4    Rozov, A.5
  • 105
    • 70349630440 scopus 로고    scopus 로고
    • Ca2+ current versus Ca2+ channel cooperativity of exocytosis
    • Matveev V, Bertram R, Sherman A (2009) Ca2+ current versus Ca2+ channel cooperativity of exocytosis. J Neurosci 29:12196-12209
    • (2009) J Neurosci , vol.29 , pp. 12196-12209
    • Matveev, V.1    Bertram, R.2    Sherman, A.3
  • 107
    • 0347724159 scopus 로고    scopus 로고
    • Adaptive stochastic-deterministic chemical kinetic simulations
    • Vasudeva K, Bhalla US (2004) Adaptive stochastic-deterministic chemical kinetic simulations. Bioinformatics 20:78-84
    • (2004) Bioinformatics , vol.20 , pp. 78-84
    • Vasudeva, K.1    Bhalla, U.S.2
  • 108
    • 3042735606 scopus 로고    scopus 로고
    • Calcium dynamics in dendritic spines and spine motility
    • Holcman S, Schuss Z, Korkotian E (2004) Calcium dynamics in dendritic spines and spine motility. Biophys J 87:81-91
    • (2004) Biophys J , vol.87 , pp. 81-91
    • Holcman, S.1    Schuss, Z.2    Korkotian, E.3
  • 109
    • 0034088691 scopus 로고    scopus 로고
    • Monte Carlo simulation of 3-D buffered Ca2+ diffusion in neuroendocrine cells
    • Gil A, Segura J, Pertusa JA, Soria B (2000) Monte Carlo simulation of 3-D buffered Ca2+ diffusion in neuroendocrine cells. Biophys J 78:13-33
    • (2000) Biophys J , vol.78 , pp. 13-33
    • Gil, A.1    Segura, J.2    Pertusa, J.A.3    Soria, B.4
  • 110
    • 0033803584 scopus 로고    scopus 로고
    • Modeling study of exocytosis in neuroendocrine cells: Influence of the geometrical parameters
    • Segura J, Gil A, Soria B (2000) Modeling study of exocytosis in neuroendocrine cells: influence of the geometrical parameters. Biophys J 79:1771-1786
    • (2000) Biophys J , vol.79 , pp. 1771-1786
    • Segura, J.1    Gil, A.2    Soria, B.3
  • 111
    • 0034068150 scopus 로고    scopus 로고
    • The probability of quantal secretion near a single calcium channel of an active zone
    • Bennett MR, Farnell L, Gibson WG (2000) The probability of quantal secretion near a single calcium channel of an active zone. Biophys J 78:2201-2221
    • (2000) Biophys J , vol.78 , pp. 2201-2221
    • Bennett, M.R.1    Farnell, L.2    Gibson, W.G.3
  • 112
    • 0034023710 scopus 로고    scopus 로고
    • The probability of quantal secretion within an array of calcium channels of an active zone
    • Bennett MR, Farnell L, Gibson WG (2000) The probability of quantal secretion within an array of calcium channels of an active zone. Biophys J 78:2222-2240
    • (2000) Biophys J , vol.78 , pp. 2222-2240
    • Bennett, M.R.1    Farnell, L.2    Gibson, W.G.3
  • 113
    • 13244262493 scopus 로고    scopus 로고
    • Consequences of molecular-level Ca2+ channel and synaptic vesicle colocalization for the Ca2+ microdomain and neurotransmitter exocytosis: A Monte Carlo study
    • Shahrezaei V, Delaney KR (2004) Consequences of molecular-level Ca2+ channel and synaptic vesicle colocalization for the Ca2+ microdomain and neurotransmitter exocytosis: a Monte Carlo study. Biophys J 87:2352-2364
    • (2004) Biophys J , vol.87 , pp. 2352-2364
    • Shahrezaei, V.1    Delaney, K.R.2
  • 114
    • 23944453323 scopus 로고    scopus 로고
    • Brevity of the Ca2+ microdomain and active zone geometry prevent Ca2+ -sensor saturation for neurotransmitter release
    • Shagrezaei V, Delaney KR (2005) Brevity of the Ca2+ microdomain and active zone geometry prevent Ca2+ -sensor saturation for neurotransmitter release. J Neurophysiol 94: 1912-1919
    • (2005) J Neurophysiol , vol.94 , pp. 1912-1919
    • Shagrezaei, V.1    Delaney, K.R.2
  • 115
    • 33845799621 scopus 로고    scopus 로고
    • Ca2+ from one or two channels controls fusion of a single vesicle at the frog neuromuscular junction
    • Shahrezaei V, Cao A, Delaney KR (2006) Ca2+ from one or two channels controls fusion of a single vesicle at the frog neuromuscular junction. J Neurosci 26:13240-13249
    • (2006) J Neurosci , vol.26 , pp. 13240-13249
    • Shahrezaei, V.1    Cao, A.2    Delaney, K.R.3
  • 116
    • 51349085999 scopus 로고    scopus 로고
    • Modeling of quantal neurotransmitter release kinetics in the presence of fi xed and mobile calcium buffers
    • Gilmanov IR, Samigullin DV, Vyskocil F, Nikolsky EE, Bukharaeva EA (2008) Modeling of quantal neurotransmitter release kinetics in the presence of fi xed and mobile calcium buffers. J Comput Neurosci 25:296-307
    • (2008) J Comput Neurosci , vol.25 , pp. 296-307
    • Gilmanov, I.R.1    Samigullin, D.V.2    Vyskocil, F.3    Nikolsky, E.E.4    Bukharaeva, E.A.5
  • 119
    • 77549087455 scopus 로고    scopus 로고
    • Exocytotic dynamics and calcium cooperativity effects in the calyx of Held synapse: A modelling study
    • Gil A, Gonzalez-Vélez V (2010) Exocytotic dynamics and calcium cooperativity effects in the calyx of Held synapse: a modelling study. J Comput Neurosci 28:65-76
    • (2010) J Comput Neurosci , vol.28 , pp. 65-76
    • Gil, A.1    Gonzalez-Vélez, V.2
  • 120
    • 0036906215 scopus 로고    scopus 로고
    • Complexity of calcium signaling in synaptic spines
    • Franks KM, Sejnowski TJ (2002) Complexity of calcium signaling in synaptic spines. Bioessays 24:1130-1144
    • (2002) Bioessays , vol.24 , pp. 1130-1144
    • Franks, K.M.1    Sejnowski, T.J.2
  • 121
    • 44349158874 scopus 로고    scopus 로고
    • Calmodulin activation by calcium transients in the postsynaptic density of dendritic spines
    • Keller DX, Franks KM, Bartol TM Jr, Sejnowski TJ (2008) Calmodulin activation by calcium transients in the postsynaptic density of dendritic spines. PLoS One 3:e2045
    • (2008) PLoS One , vol.3
    • Keller, D.X.1    Franks, K.M.2    Bartol Jr., T.M.3    Sejnowski, T.J.4
  • 122
    • 45049084913 scopus 로고    scopus 로고
    • Calcium microdomains at presynaptic active zones of vertebrate hair cells unmasked by stochastic deconvolution
    • Bortolozzi M, Lelli A, Mammano F (2008) Calcium microdomains at presynaptic active zones of vertebrate hair cells unmasked by stochastic deconvolution. Cell Calcium 44:158-168
    • (2008) Cell Calcium , vol.44 , pp. 158-168
    • Bortolozzi, M.1    Lelli, A.2    Mammano, F.3
  • 123
    • 0019732589 scopus 로고
    • Simulation of intracellular Ca2+ oscillation in a sympathetic neurone
    • Kuba K, Takeshita S (1981) Simulation of intracellular Ca2+ oscillation in a sympathetic neurone. J Theor Biol 93:1009-1031
    • (1981) J Theor Biol , vol.93 , pp. 1009-1031
    • Kuba, K.1    Takeshita, S.2
  • 124
    • 0028986520 scopus 로고
    • [Ca2+]i oscillations in sympathetic neurons: An experimental test of a theoretical model
    • Friel DD (1995) [Ca2+] i oscillations in sympathetic neurons: an experimental test of a theoretical model. Biophys J 68:1752-1766
    • (1995) Biophys J , vol.68 , pp. 1752-1766
    • Friel, D.D.1
  • 125
    • 0034106616 scopus 로고    scopus 로고
    • Modes of propagation of Ca2+ -induced Ca2+ release in bullfrog sympathetic ganglion cells
    • Hua SY, Liu C, Lu FM, Nohmi M, Kuba K (2000) Modes of propagation of Ca2+ -induced Ca2+ release in bullfrog sympathetic ganglion cells. Cell Calcium 27:195-204
    • (2000) Cell Calcium , vol.27 , pp. 195-204
    • Hua, S.Y.1    Liu, C.2    Lu, F.M.3    Nohmi, M.4    Kuba, K.5
  • 126
    • 0034671230 scopus 로고    scopus 로고
    • Origin sites of calcium release and calcium oscillations in frog sympathetic neurons
    • McDonough SI, Cseresnyés Z, Schneider MF (2000) Origin sites of calcium release and calcium oscillations in frog sympathetic neurons. J Neurosci 20:9059-9070
    • (2000) J Neurosci , vol.20 , pp. 9059-9070
    • McDonough, S.I.1    Cseresnyés, Z.2    Schneider, M.F.3
  • 131
    • 0026656286 scopus 로고
    • Evaluation of cellular mechanisms for modulation of calcium transients using a mathematical model of fura-2 Ca2+ imaging in Aplysia sensory neurons
    • Blumenfeld H, Zablow L, Sabatini B (1992) Evaluation of cellular mechanisms for modulation of calcium transients using a mathematical model of fura-2 Ca2+ imaging in Aplysia sensory neurons. Biophys J 63:1146-1164
    • (1992) Biophys J , vol.63 , pp. 1146-1164
    • Blumenfeld, H.1    Zablow, L.2    Sabatini, B.3
  • 132
    • 0027530592 scopus 로고
    • Time course of calcium and calcium-bound buffers following calcium influx in a model cell
    • Nowycky MC, Pinter MJ (1993) Time course of calcium and calcium-bound buffers following calcium influx in a model cell. Biophys J 64:77-91
    • (1993) Biophys J , vol.64 , pp. 77-91
    • Nowycky, M.C.1    Pinter, M.J.2
  • 133
    • 0033803101 scopus 로고    scopus 로고
    • Development and dissipation of Ca2+ gradients in adrenal chromaffi n cells
    • Marengo FD, Monck JR (2000) Development and dissipation of Ca2+ gradients in adrenal chromaffi n cells. Biophys J 79:1800-1820
    • (2000) Biophys J , vol.79 , pp. 1800-1820
    • Marengo, F.D.1    Monck, J.R.2
  • 134
    • 0031030834 scopus 로고    scopus 로고
    • Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses
    • Sinha SR, Wu LG, Saggau P (1997) Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. Biophys J 72:637-651
    • (1997) Biophys J , vol.72 , pp. 637-651
    • Sinha, S.R.1    Wu, L.G.2    Saggau, P.3
  • 135
    • 0030609825 scopus 로고    scopus 로고
    • Low mobility of the Ca2+ buffers in axons of cultured Aplysia neurons
    • Gabso M, Neher E, Spira ME (1997) Low mobility of the Ca2+ buffers in axons of cultured Aplysia neurons. Neuron 18:473-481
    • (1997) Neuron , vol.18 , pp. 473-481
    • Gabso, M.1    Neher, E.2    Spira, M.E.3
  • 136
    • 39049171332 scopus 로고    scopus 로고
    • Calcium signal transmission in chick sensory neurones is diffusion based
    • Coatesworth W, Bolsover S (2008) Calcium signal transmission in chick sensory neurones is diffusion based. Cell Calcium 43:236-249
    • (2008) Cell Calcium , vol.43 , pp. 236-249
    • Coatesworth, W.1    Bolsover, S.2
  • 137
    • 0031055465 scopus 로고    scopus 로고
    • Ca2+ -induced Ca2+ release phenomena in mammalian sympathetic neurons are critically dependent on the rate of rise of trigger Ca2+
    • Hernandez-Cruz A, Escobar AL, Jiménez N (1997) Ca2+ -induced Ca2+ release phenomena in mammalian sympathetic neurons are critically dependent on the rate of rise of trigger Ca2+ . J Gen Physiol 109:147-167
    • (1997) J Gen Physiol , vol.109 , pp. 147-167
    • Hernandez-Cruz, A.1    Escobar, A.L.2    Jiménez, N.3
  • 138
    • 19044387113 scopus 로고    scopus 로고
    • Modulation of presynaptic Ca2+ entry by AMPA receptors at individual GABAergic synapses in the cerebellum
    • Rusakov DA, Saitow F, Lehre KP, Konishi S (2005) Modulation of presynaptic Ca2+ entry by AMPA receptors at individual GABAergic synapses in the cerebellum. J Neurosci 25: 4930-4940
    • (2005) J Neurosci , vol.25 , pp. 4930-4940
    • Rusakov, D.A.1    Saitow, F.2    Lehre, K.P.3    Konishi, S.4
  • 139
    • 0031780887 scopus 로고    scopus 로고
    • Competitive calcium binding: Implications for dendritic calcium signaling
    • Markram H, Roth A, Helmchen F (1998) Competitive calcium binding: implications for dendritic calcium signaling. J Comput Neurosci 5:331-348
    • (1998) J Comput Neurosci , vol.5 , pp. 331-348
    • Markram, H.1    Roth, A.2    Helmchen, F.3
  • 140
    • 0041353463 scopus 로고    scopus 로고
    • Mutational analysis of dendritic Ca2+ kinetics in rodent Purkinje cells: Role of parvalbumin and calbindin D28k
    • Schmidt H, Stiefel KM, Racay P, Schwaller B, Eilers J (2003) Mutational analysis of dendritic Ca2+ kinetics in rodent Purkinje cells: role of parvalbumin and calbindin D28k. J Physiol 551:13-32
    • (2003) J Physiol , vol.551 , pp. 13-32
    • Schmidt, H.1    Stiefel, K.M.2    Racay, P.3    Schwaller, B.4    Eilers, J.5
  • 141
    • 34249702242 scopus 로고    scopus 로고
    • Spino-dendritic cross-talk in rodent Purkinje neurons mediated by endogenous Ca2+ -binding proteins
    • Schmidt H, Kunerth S, Wilms C, Strotmann R, Eilers J (2007) Spino-dendritic cross-talk in rodent Purkinje neurons mediated by endogenous Ca2+ -binding proteins. J Physiol 581:619-629
    • (2007) J Physiol , vol.581 , pp. 619-629
    • Schmidt, H.1    Kunerth, S.2    Wilms, C.3    Strotmann, R.4    Eilers, J.5
  • 142
    • 69549112941 scopus 로고    scopus 로고
    • Spine neck geometry determines spino-dendritic cross-talk in the presence of mobile endogenous calcium binding proteins
    • Schmidt H, Eilers J (2009) Spine neck geometry determines spino-dendritic cross-talk in the presence of mobile endogenous calcium binding proteins. J Comput Neurosci 27:229-243
    • (2009) J Comput Neurosci , vol.27 , pp. 229-243
    • Schmidt, H.1    Eilers, J.2
  • 143
    • 0037204078 scopus 로고    scopus 로고
    • Calcium dynamics of spines depend on their dendritic location
    • Holthoff K, Tsay D, Yuste R (2002) Calcium dynamics of spines depend on their dendritic location. Neuron 33:425-437
    • (2002) Neuron , vol.33 , pp. 425-437
    • Holthoff, K.1    Tsay, D.2    Yuste, R.3
  • 145
    • 58049202237 scopus 로고    scopus 로고
    • Dendritic spike saturation of endogenous calcium buffer and induction of postsynaptic cerebellar LTP
    • Canepari M, Vogt KE (2008) Dendritic spike saturation of endogenous calcium buffer and induction of postsynaptic cerebellar LTP. PLoS One 3:e4011
    • (2008) PLoS One , vol.3
    • Canepari, M.1    Vogt, K.E.2
  • 146
    • 0028334953 scopus 로고
    • A model of dendritic spine Ca2+ concentration exploring possible bases for a sliding synaptic modifi cation threshold
    • Gold JI, Bear MF (1994) A model of dendritic spine Ca2+ concentration exploring possible bases for a sliding synaptic modifi cation threshold. Proc Natl Acad Sci USA 91:3941-3945
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3941-3945
    • Gold, J.I.1    Bear, M.F.2
  • 147
    • 0028980681 scopus 로고
    • Intracellular Ca2+ stores can account for the time course of LTP induction: A model of Ca2+ dynamics in dendritic spines
    • Schiegg A, Gerstner W, Ritz R, van Hemmen JL (1995) Intracellular Ca2+ stores can account for the time course of LTP induction: a model of Ca2+ dynamics in dendritic spines. J Neurophysiol 74:1046-1055
    • (1995) J Neurophysiol , vol.74 , pp. 1046-1055
    • Schiegg, A.1    Gerstner, W.2    Ritz, R.3    Van Hemmen, J.L.4
  • 149
    • 0025328567 scopus 로고
    • Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes
    • Holmes WR, Levy WB (1990) Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes. J Neurophysiol 63:1148-1168
    • (1990) J Neurophysiol , vol.63 , pp. 1148-1168
    • Holmes, W.R.1    Levy, W.B.2
  • 150
    • 0032797839 scopus 로고    scopus 로고
    • Geometry of dendritic spines affects calcium dynamics in hippocampal neurons: Theory and experiments
    • Volfovsky N, Parnas H, Segal M, Korkotian E (1999) Geometry of dendritic spines affects calcium dynamics in hippocampal neurons: theory and experiments. J Neurophysiol 82:450-462
    • (1999) J Neurophysiol , vol.82 , pp. 450-462
    • Volfovsky, N.1    Parnas, H.2    Segal, M.3    Korkotian, E.4
  • 151
    • 42449090738 scopus 로고    scopus 로고
    • High speed two-photon imaging of calcium dynamics in dendritic spines: Consequences for spine calcium kinetics and buffer capacity
    • Cornelisse LN, van Elburg RA, Meredith RM, Yuste R, Mansvelder HD (2007) High speed two-photon imaging of calcium dynamics in dendritic spines: consequences for spine calcium kinetics and buffer capacity. PLoS One 2:e1073
    • (2007) PLoS One , vol.2
    • Cornelisse, L.N.1    Van Elburg, R.A.2    Meredith, R.M.3    Yuste, R.4    Mansvelder, H.D.5
  • 152
    • 12844262322 scopus 로고    scopus 로고
    • Inositol 1,4,5-trisphosphate-dependent Ca2+ threshold dynamics detect spike timing in cerebellar Purkinje cells
    • Doi T, Kuroda S, Michikawa T, Kawato M (2005) Inositol 1,4,5-trisphosphate-dependent Ca2+ threshold dynamics detect spike timing in cerebellar Purkinje cells. J Neurosci 25:950-961
    • (2005) J Neurosci , vol.25 , pp. 950-961
    • Doi, T.1    Kuroda, S.2    Michikawa, T.3    Kawato, M.4
  • 153
    • 77953457529 scopus 로고    scopus 로고
    • Calcium, synaptic plasticity and intrinsic homeostasis in Purkinje neuron models
    • Achard P, De Schutter E (2008) Calcium, synaptic plasticity and intrinsic homeostasis in Purkinje neuron models. Front Comput Neurosci 2:8
    • (2008) Front Comput Neurosci , vol.2 , pp. 8
    • Achard, P.1    De Schutter, E.2
  • 154
    • 0001059645 scopus 로고    scopus 로고
    • Calcium dynamics in large neuronal models
    • Koch C, Segev I (eds) 2nd edn. MIT, Cambridge
    • De Schutter E, Smolen P (1998) Calcium dynamics in large neuronal models. In: Koch C, Segev I (eds) Methods in neuronal modeling: from ions to networks, 2nd edn. MIT, Cambridge, pp 211-250
    • (1998) Methods in Neuronal Modeling: From Ions to Networks , pp. 211-250
    • De Schutter, E.1    Smolen, P.2
  • 155
    • 0034930823 scopus 로고    scopus 로고
    • Multiple modes of calcium-induced calcium release in sympathetic neurons I: Attenuation of endoplasmic reticulum Ca2+ accumulation at low [Ca2+] i during weak depolarization
    • Albrecht MA, Colegrove SL, Hongpaisan J, Pivovarova NB, Andrews SB, Friel DD (2001) Multiple modes of calcium-induced calcium release in sympathetic neurons I: attenuation of endoplasmic reticulum Ca2+ accumulation at low [Ca2+] i during weak depolarization. J Gen Physiol 118:83-110
    • (2001) J Gen Physiol , vol.118 , pp. 83-110
    • Albrecht, M.A.1    Colegrove, S.L.2    Hongpaisan, J.3    Pivovarova, N.B.4    Andrews, S.B.5    Friel, D.D.6
  • 156
    • 84864667885 scopus 로고    scopus 로고
    • Controlling Ca2+ -activated K + channels with models of Ca2+ buffering in Purkinje cells
    • Epub ahead of print
    • Anwar H, Hong S, De Schutter E (2010) Controlling Ca2+ -activated K + channels with models of Ca2+ buffering in Purkinje cells. Cerebellum Epub ahead of print
    • (2010) Cerebellum
    • Anwar, H.1    Hong, S.2    De Schutter, E.3
  • 157
    • 38049068035 scopus 로고    scopus 로고
    • Calcium dynamics: Analyzing the Ca2+ regulatory network in intact cells
    • Friel DD, Chiel HJ (2008) Calcium dynamics: analyzing the Ca2+ regulatory network in intact cells. Trends Neurosci 31:8-19
    • (2008) Trends Neurosci , vol.31 , pp. 8-19
    • Friel, D.D.1    Chiel, H.J.2
  • 160
    • 37249064186 scopus 로고    scopus 로고
    • Resolving the fast kinetics of cooperative binding: Ca2+ buffering by calretinin
    • Faas GC, Schwaller B, Vergara JL, Mody I (2007) Resolving the fast kinetics of cooperative binding: Ca2+ buffering by calretinin. PLoS Biol 5:e311
    • (2007) PLoS Biol , vol.5
    • Faas, G.C.1    Schwaller, B.2    Vergara, J.L.3    Mody, I.4
  • 161
    • 0028221324 scopus 로고
    • Calcium and magnesium binding to rat parvalbumin
    • Eberhard M, Erne P (1994) Calcium and magnesium binding to rat parvalbumin. Eur J Biochem 222:21-26
    • (1994) Eur J Biochem , vol.222 , pp. 21-26
    • Eberhard, M.1    Erne, P.2
  • 162
    • 17644411077 scopus 로고    scopus 로고
    • Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons
    • Schmidt H, Schwaller B, Eilers J (2005) Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons. Proc Natl Acad Sci USA 102:5850-5855
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5850-5855
    • Schmidt, H.1    Schwaller, B.2    Eilers, J.3
  • 163
    • 0037379710 scopus 로고    scopus 로고
    • Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching
    • Schmidt H, Brown EB, Schwaller B, Eilers J (2003) Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching. Biophys J 84:2599-2608
    • (2003) Biophys J , vol.84 , pp. 2599-2608
    • Schmidt, H.1    Brown, E.B.2    Schwaller, B.3    Eilers, J.4
  • 164
    • 0027316317 scopus 로고
    • Axons and axon terminals of cerebellar Purkinje cells and basket cells have higher levels of parvalbumin immunoreactivity than somata and dendrites: Quantitative analysis by immunogold labeling
    • Kosaka T, Kosaka K, Nakayama T, Hunziker W, Heizmann CW (1993) Axons and axon terminals of cerebellar Purkinje cells and basket cells have higher levels of parvalbumin immunoreactivity than somata and dendrites: quantitative analysis by immunogold labeling. Exp Brain Res 93:483-491
    • (1993) Exp Brain Res , vol.93 , pp. 483-491
    • Kosaka, T.1    Kosaka, K.2    Nakayama, T.3    Hunziker, W.4    Heizmann, C.W.5
  • 165
    • 84859918382 scopus 로고    scopus 로고
    • Diffusion and extrusion shape standing calcium gradients during ongoing parallel fiber activity in dendrites of Purkinje neurons
    • Epub ahead of print
    • Schmidt H, Arendt O, Eilers J (2010) Diffusion and extrusion shape standing calcium gradients during ongoing parallel fiber activity in dendrites of Purkinje neurons Cerebellum Epub ahead of print
    • (2010) Cerebellum
    • Schmidt, H.1    Arendt, O.2    Eilers, J.3
  • 166
    • 0030611431 scopus 로고    scopus 로고
    • Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffi n cells
    • Xu T, Naraghi M, Kang H, Neher E (1997) Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffi n cells. Biophys J 73:532-545
    • (1997) Biophys J , vol.73 , pp. 532-545
    • Xu, T.1    Naraghi, M.2    Kang, H.3    Neher, E.4
  • 167
    • 0033257453 scopus 로고    scopus 로고
    • Supralinear Ca2+ signaling by cooperative and mobile Ca2+ buffering in Purkinje neurons
    • Maeda H, Ellis-Davies GC, Ito K, Miyashita Y, Kasai H (1999) Supralinear Ca2+ signaling by cooperative and mobile Ca2+ buffering in Purkinje neurons. Neuron 24:989-1002
    • (1999) Neuron , vol.24 , pp. 989-1002
    • Maeda, H.1    Ellis-Davies, G.C.2    Ito, K.3    Miyashita, Y.4    Kasai, H.5
  • 168
    • 49049094473 scopus 로고    scopus 로고
    • Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activity and calcium in vivo and in vitro
    • Hendel T, Mank M, Schnell B, Griesbeck O, Borst A, Reiff D (2008) Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activity and calcium in vivo and in vitro. J Neurosci 28:7399-7411
    • (2008) J Neurosci , vol.28 , pp. 7399-7411
    • Hendel, T.1    Mank, M.2    Schnell, B.3    Griesbeck, O.4    Borst, A.5    Reiff, D.6
  • 169
    • 0020973068 scopus 로고
    • Sarcoplasmic reticulum calcium release in frog skeletal muscle fibres estimated from Arsenazo III calcium transients
    • Baylor SM, Chandler WK, Marshall MW (1983) Sarcoplasmic reticulum calcium release in frog skeletal muscle fi bres estimated from Arsenazo III calcium transients. J Physiol 344:625-666
    • (1983) J Physiol , vol.344 , pp. 625-666
    • Baylor, S.M.1    Chandler, W.K.2    Marshall, M.W.3
  • 170
    • 0020644361 scopus 로고
    • Measurement and modifi cation of free calcium transients in frog skeletal muscle fi bres by a metallochromic indicator dye
    • Kovacs L, Rios E, Schneider MF (1983) Measurement and modifi cation of free calcium transients in frog skeletal muscle fi bres by a metallochromic indicator dye. J Physiol 343:161-196
    • (1983) J Physiol , vol.343 , pp. 161-196
    • Kovacs, L.1    Rios, E.2    Schneider, M.F.3
  • 171
    • 0023351140 scopus 로고
    • A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers
    • Melzer W, Rios E, Schneider MF (1987) A general procedure for determining the rate of calcium release from the sarcoplasmic reticulum in skeletal muscle fibers. Biophys J 51:849-863
    • (1987) Biophys J , vol.51 , pp. 849-863
    • Melzer, W.1    Rios, E.2    Schneider, M.F.3
  • 172
    • 0347093222 scopus 로고    scopus 로고
    • Voltage-dependent Ca2+ fluxes in skeletal myotubes determined using a removal model analysis
    • Schuhmeier RP, Melzer W (2004) Voltage-dependent Ca2+ fluxes in skeletal myotubes determined using a removal model analysis. J Gen Physiol 123:33-51
    • (2004) J Gen Physiol , vol.123 , pp. 33-51
    • Schuhmeier, R.P.1    Melzer, W.2
  • 173
    • 0026135106 scopus 로고
    • Flux of Ca2+ across the sarcoplasmic reticulum of guinea-pig cardiac cells during excitation-contraction coupling
    • Sipido KR, Wier WG (1991) Flux of Ca2+ across the sarcoplasmic reticulum of guinea-pig cardiac cells during excitation-contraction coupling. J Physiol 435:605-630
    • (1991) J Physiol , vol.435 , pp. 605-630
    • Sipido, K.R.1    Wier, W.G.2
  • 174
    • 0034942111 scopus 로고    scopus 로고
    • Multiple modes of calcium-induced calcium release in sympathetic neurons II: A [Ca2+] i -and location-dependent transition from endoplasmic reticulum Ca2+ accumulation to net release Ca2+ release
    • Hongpaisan J, Pivovarova NB, Colegrove SL, Leapman RD, Friel DD, Andrews SB (2001) Multiple modes of calcium-induced calcium release in sympathetic neurons II: a [Ca2+] i -and location-dependent transition from endoplasmic reticulum Ca2+ accumulation to net release Ca2+ release. J Gen Physiol 118:101-112
    • (2001) J Gen Physiol , vol.118 , pp. 101-112
    • Hongpaisan, J.1    Pivovarova, N.B.2    Colegrove, S.L.3    Leapman, R.D.4    Friel, D.D.5    Andrews, S.B.6
  • 175
    • 0034145480 scopus 로고    scopus 로고
    • Dissection of mitochondrial Ca2+ uptake and release fluxes in situ after depolarization-evoked [Ca2+] i elevations in sympathetic neurons
    • Colegrove SL, Albrecht MA, Friel DD (2000) Dissection of mitochondrial Ca2+ uptake and release fluxes in situ after depolarization-evoked [Ca2+] i elevations in sympathetic neurons. J Gen Physiol 115:351-370
    • (2000) J Gen Physiol , vol.115 , pp. 351-370
    • Colegrove, S.L.1    Albrecht, M.A.2    Friel, D.D.3
  • 176
    • 0033818161 scopus 로고    scopus 로고
    • Quantitative analysis of mitochondrial Ca2+ uptake and release pathways in sympathetic neurons. Reconstruction of the recovery after depolarization-evoked [Ca2+] i elevations
    • Colegrove SL, Albrecht MA, Friel DD (2000) Quantitative analysis of mitochondrial Ca2+ uptake and release pathways in sympathetic neurons. Reconstruction of the recovery after depolarization-evoked [Ca2+] i elevations. J Gen Physiol 115:371-388
    • (2000) J Gen Physiol , vol.115 , pp. 371-388
    • Colegrove, S.L.1    Albrecht, M.A.2    Friel, D.D.3
  • 177
    • 0036098486 scopus 로고    scopus 로고
    • Differential regulation of ER Ca2+ uptake and release rates accounts for multiple modes of Ca2+ -induced Ca2+ release
    • Albrecht MA, Colegrove SL, Friel DD (2002) Differential regulation of ER Ca2+ uptake and release rates accounts for multiple modes of Ca2+ -induced Ca2+ release. J Gen Physiol 119:211-233
    • (2002) J Gen Physiol , vol.119 , pp. 211-233
    • Albrecht, M.A.1    Colegrove, S.L.2    Friel, D.D.3
  • 179
    • 33644847375 scopus 로고    scopus 로고
    • Microdomains of intracellular Ca2+: Molecular determinants and functional consequences
    • Rizzuto R, Pozzan T (2006) Microdomains of intracellular Ca2+ : molecular determinants and functional consequences. Physiol Rev 86:369-408
    • (2006) Physiol Rev , vol.86 , pp. 369-408
    • Rizzuto, R.1    Pozzan, T.2
  • 181
  • 182
    • 33744928049 scopus 로고    scopus 로고
    • Synapse-specific plasticity and compartmentalized signaling in cerebellar stellate cells
    • Soler-Llavina GJ, Sabatini BL (2006) Synapse-specific plasticity and compartmentalized signaling in cerebellar stellate cells. Nat Neurosci 9:798-806
    • (2006) Nat Neurosci , vol.9 , pp. 798-806
    • Soler-Llavina, G.J.1    Sabatini, B.L.2
  • 183
    • 60449088070 scopus 로고    scopus 로고
    • Computational study of non-homogeneous distribution of Ca2+ handling systems in cerebellar granule cells
    • Saftenku EE (2009) Computational study of non-homogeneous distribution of Ca2+ handling systems in cerebellar granule cells. J Theor Biol 257:228-244
    • (2009) J Theor Biol , vol.257 , pp. 228-244
    • Saftenku, E.E.1
  • 184
    • 84858996960 scopus 로고    scopus 로고
    • Models of calcium dynamics in cerebellar granule cells
    • Epub ahead of print
    • Saftenku EE (2010) Models of calcium dynamics in cerebellar granule cells. Cerebellum Epub ahead of print
    • Cerebellum , vol.2010
    • Saftenku, E.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.