-
1
-
-
70349238897
-
Membranebound fas ligand requires rip1 for efficient activation of caspase-8 within the deathinducingsignaling complex
-
Morgan MJ, Kim YS, Liu ZG: Membranebound fas ligand requires rip1 for efficient activation of caspase-8 within the deathinducingsignaling complex. J Immunol 2009;183:3278-3284.
-
(2009)
J Immunol
, vol.183
, pp. 3278-3284
-
-
Morgan, M.J.1
Kim, Y.S.2
Liu, Z.G.3
-
2
-
-
43049152912
-
TNF-α induces two distinct caspase-8 activation pathways
-
DOI 10.1016/j.cell.2008.03.036, PII S0092867408005011
-
Wang L, Du F, Wang X: Tnf-alpha induces two distinct caspase-8 activation pathways. Cell 2008;133:693-703. (Pubitemid 351636305)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
3
-
-
79959467279
-
Caspase 3 is activated through caspase 8 instead ofcaspase 9 during H2O2-induced apoptosis in hela cells
-
Wu Y, Wang D, Wang X, Wang Y, Ren F, Chang D, Chang Z, Jia B: Caspase 3 is activated through caspase 8 instead ofcaspase 9 during H2O2-induced apoptosis in hela cells. Cell Physiol Biochem 2011;27:539-546.
-
(2011)
Cell Physiol Biochem
, vol.27
, pp. 539-546
-
-
Wu, Y.1
Wang, D.2
Wang, X.3
Wang, Y.4
Ren, F.5
Chang, D.6
Chang, Z.7
Jia, B.8
-
4
-
-
35348995145
-
Ligand bound beta 1 integrins inhibit procaspase-8 formediating cell adhesion-mediated drug and radiation resistance in human leukemia cells
-
Estrugo D, Fischer A, Hess F, Scherthan H, Belka C, Cordes N: Ligand bound beta 1 integrins inhibit procaspase-8 formediating cell adhesion-mediated drug and radiation resistance in human leukemia cells. PLoS O 2007;2:11.
-
(2007)
PLoS O
, vol.2
, pp. 11
-
-
Estrugo, D.1
Fischer, A.2
Hess, F.3
Scherthan, H.4
Belka, C.5
Cordes, N.6
-
5
-
-
33748571986
-
Activation of caspase-8 triggers anoikis in human neuroblastoma cells
-
DOI 10.1016/j.neures.2006.06.008, PII S0168010206001696
-
Bozzo C, Sabbatini M, Tiberio R, Piffanelli V, Santoro C, Cannas M: Activation of caspase-8 triggers anoikis in human neuroblastoma cells. Neurosci Res 2006;56:145-153. (Pubitemid 44374786)
-
(2006)
Neuroscience Research
, vol.56
, Issue.2
, pp. 145-153
-
-
Bozzo, C.1
Sabbatini, M.2
Tiberio, R.3
Piffanelli, V.4
Santoro, C.5
Cannas, M.6
-
6
-
-
30144434107
-
Potentiation of neuroblastoma metastasis by loss of caspase-8
-
DOI 10.1038/nature04323
-
Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA: Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature 2006;439:95-99. (Pubitemid 43053635)
-
(2006)
Nature
, vol.439
, Issue.7072
, pp. 95-99
-
-
Stupack, D.G.1
Teitz, T.2
Potter, M.D.3
Mikolon, D.4
Houghton, P.J.5
Kidd, V.J.6
Lahti, J.M.7
Cheresh, D.A.8
-
7
-
-
49949110101
-
Caspase-8 deficiency facilitates cellular transformation in vitro
-
Krelin Y, Zhang L, Kang TB, Appel E, Kovalenko A, Wallach D: Caspase-8 deficiency facilitates cellular transformation in vitro. Cell Death Differ 2008;15:1350-1355.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1350-1355
-
-
Krelin, Y.1
Zhang, L.2
Kang, T.B.3
Appel, E.4
Kovalenko, A.5
Wallach, D.6
-
9
-
-
65949097277
-
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
-
Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barila D, Lahti JM, Schlaepfer D, Stupack DG: Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res2009;69:3755-3763.
-
(2009)
Cancer Res
, vol.69
, pp. 3755-3763
-
-
Barbero, S.1
Mielgo, A.2
Torres, V.3
Teitz, T.4
Shields, D.J.5
Mikolon, D.6
Bogyo, M.7
Barila, D.8
Lahti, J.M.9
Schlaepfer, D.10
Stupack, D.G.11
-
10
-
-
75749103348
-
Src signaling in cancer invasion
-
Guarino M: Src signaling in cancer invasion. J Cell Physiol 2010;223:14-26.
-
(2010)
J Cell Physiol
, vol.223
, pp. 14-26
-
-
Guarino, M.1
-
11
-
-
67449124366
-
Critical role for caspase-8 in epidermal growth factor signaling
-
Finlay D, Howes A, Vuori K: Critical role for caspase-8 in epidermal growth factor signaling. Cancer Res 2009;69:5023-5029.
-
(2009)
Cancer Res
, vol.69
, pp. 5023-5029
-
-
Finlay, D.1
Howes, A.2
Vuori, K.3
-
12
-
-
37549060944
-
Novel noncatalytic role for caspase-8 in promoting srcmediated adhesion and erk signaling in neuroblastoma cells
-
Finlay D, Vuori K: Novel noncatalytic role for caspase-8 in promoting srcmediated adhesion and erk signaling in neuroblastoma cells. Cancer Res 2007;67:11704-11711.
-
(2007)
Cancer Res
, vol.67
, pp. 11704-11711
-
-
Finlay, D.1
Vuori, K.2
-
13
-
-
33646542701
-
Src kinase phosphorylates caspase-8 on tyr380: A novel mechanism of apoptosis suppression
-
Cursi S, Rufini A, Stagni V, Condo I, Matafora V, Bachi A, Bonifazi AP, Coppola L, Superti-Furga G, Testi R, Barila D: Src kinase phosphorylates caspase-8 on tyr380: A novel mechanism of apoptosis suppression. EMBO J 2006;25:1895-1905.
-
(2006)
EMBO J
, vol.25
, pp. 1895-1905
-
-
Cursi, S.1
Rufini, A.2
Stagni, V.3
Condo, I.4
Matafora, V.5
Bachi, A.6
Bonifazi, A.P.7
Coppola, L.8
Superti-Furga, G.9
Testi, R.10
Barila, D.11
-
14
-
-
49949104482
-
A tumour suppressor function of caspase-8?
-
Knight RA, Vaux DL: A tumour suppressor function of caspase-8? Cell Death Differ 2008;15:1337-1338.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1337-1338
-
-
Knight, R.A.1
Vaux, D.L.2
-
15
-
-
70449699768
-
Caspase-8 as a potential mediator of protumorigenic signals
-
Finlay D, Howes A, Vuori K: Caspase-8 as a potential mediator of protumorigenic signals. Cell Cycle 2009;8:3441-3442.
-
(2009)
Cell Cycle
, vol.8
, pp. 3441-3442
-
-
Finlay, D.1
Howes, A.2
Vuori, K.3
-
16
-
-
49649096191
-
Caspase-8: Fly or die
-
Frisch SM: Caspase-8: Fly or die. Cancer Res 2008;68:4491-4493.
-
(2008)
Cancer Res
, vol.68
, pp. 4491-4493
-
-
Frisch, S.M.1
-
17
-
-
65349132693
-
Emt, the cytoskeleton, and cancer cell invasion
-
Yilmaz M, Christofori G: Emt, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev 2009;28:15-33.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 15-33
-
-
Yilmaz, M.1
Christofori, G.2
-
18
-
-
0036894603
-
A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction
-
Zijlstra A, Mellor R, Panzarella G, Aimes RT, Hooper JD, Marchenko ND, Quigley JP: A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction. Cancer Res2002;62:7083-7092. (Pubitemid 35424104)
-
(2002)
Cancer Research
, vol.62
, Issue.23
, pp. 7083-7092
-
-
Zijlstra, A.1
Mellor, R.2
Panzarella, G.3
Aimes, R.T.4
Hooper, J.D.5
Marchenko, N.D.6
Quigley, J.P.7
-
19
-
-
0032493871
-
Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
-
DOI 10.1016/S0092-8674(00)81478-6
-
Kim J, Yu W, Kovalski K, Ossowski L: Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative pcr-based assay. Cell 1998;94:353-362. (Pubitemid 28376079)
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 353-362
-
-
Kim, J.1
Yu, W.2
Kovalski, K.3
Ossowski, L.4
-
20
-
-
33644849647
-
Src activation is not necessary for transforming growth factor (TGF)-β-mediated epithelial to mesenchymal transitions (EMT) in mammary epithelial cells: PP1 directly inhibits TGF-β receptors I and II
-
DOI 10.1074/jbc.M503304200
-
Maeda M, Shintani Y, Wheelock MJ, Johnson KR: Src activation is not necessary for transforming growth factor (tgf)-beta-mediated epithelial to mesenchymal transitions (emt) in mammary epithelial cells. Pp1 directly inhibits tgf-beta receptors i and ii. J Biol Chem 2006;281:59-68. (Pubitemid 43671163)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.1
, pp. 59-68
-
-
Maeda, M.1
Shintani, Y.2
Wheelock, M.J.3
Johnson, K.R.4
-
21
-
-
85047696594
-
Src kinase contributes to the metastatic spread of carcinoma cells
-
DOI 10.1038/sj/onc/1205298
-
Boyer B, Bourgeois Y, Poupon MF: Src kinase contributes to the metastatic spread of carcinoma cells. Oncogene 2002;21:2347-2356. (Pubitemid 34407294)
-
(2002)
Oncogene
, vol.21
, Issue.15
, pp. 2347-2356
-
-
Boyer, B.1
Bourgeois, Y.2
Poupon, M.-F.3
-
22
-
-
7944224012
-
Integrin β4 signaling promotes tumor angiogenesis
-
DOI 10.1016/j.ccr.2004.09.029, PII S1535610804002995
-
Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG: Integrin beta4 signaling promotes tumor angiogenesis. Cancer Cell 2004;6:471-483. (Pubitemid 39469983)
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 471-483
-
-
Nikolopoulos, S.N.1
Blaikie, P.2
Yoshioka, T.3
Guo, W.4
Giancotti, F.G.5
-
24
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011;61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
25
-
-
55949128738
-
Non-apoptotic functions of caspase-8
-
Maelfait J, Beyaert R: Non-apoptotic functions of caspase-8. Biochem Pharmacol 2008;76:1365-1373.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1365-1373
-
-
Maelfait, J.1
Beyaert, R.2
-
26
-
-
77956537387
-
From procaspase- 8 to caspase-8: Revisiting structural functions of caspase-8
-
Zhao Y, Sui X, Ren H: From procaspase- 8 to caspase-8: Revisiting structural functions of caspase-8. J Cell Physiol 2010;225:316-320.
-
(2010)
J Cell Physiol
, vol.225
, pp. 316-320
-
-
Zhao, Y.1
Sui, X.2
Ren, H.3
-
28
-
-
46249085203
-
Src as a potential therapeutic target in non-small-cell lung cancer
-
DOI 10.1093/annonc/mdn048
-
Giaccone G, Zucali PA: Src as a potential therapeutic target in non-small-cell lung cancer. Ann Oncol 2008;19:1219-1223. (Pubitemid 351911949)
-
(2008)
Annals of Oncology
, vol.19
, Issue.7
, pp. 1219-1223
-
-
Giaccone, G.1
Zucali, P.A.2
-
30
-
-
77949541114
-
Studies of the molecular mechanism of caspase- 8 activation by solution nmr
-
Keller N, Grutter MG, Zerbe O: Studies of the molecular mechanism of caspase- 8 activation by solution nmr. Cell Death Differ 2010;17:710-718.
-
(2010)
Cell Death Differ
, vol.17
, pp. 710-718
-
-
Keller, N.1
Grutter, M.G.2
Zerbe, O.3
-
31
-
-
61449175831
-
Structural and biochemical studies on procaspase-8: New insights on initiator caspase activation
-
Keller N, Mares J, Zerbe O, Grutter MG: Structural and biochemical studies on procaspase-8: New insights on initiator caspase activation. Structure 2009;17:438-448.
-
(2009)
Structure
, vol.17
, pp. 438-448
-
-
Keller, N.1
Mares, J.2
Zerbe, O.3
Grutter, M.G.4
-
32
-
-
77952784381
-
Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation
-
Oberst A, Pop C, Tremblay AG, Blais V, Denault JB, Salvesen GS, Green DR: Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation. J Biol Chem 2010;285:16632-16642
-
(2010)
J Biol Chem
, vol.285
, pp. 16632-16642
-
-
Oberst, A.1
Pop, C.2
Tremblay, A.G.3
Blais, V.4
Denault, J.B.5
Salvesen, G.S.6
Green, D.R.7
-
33
-
-
37549062115
-
Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility
-
Senft J, Helfer B, Frisch SM: Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility. Cancer Res 2007;67:11505-11509.
-
(2007)
Cancer Res
, vol.67
, pp. 11505-11509
-
-
Senft, J.1
Helfer, B.2
Frisch, S.M.3
-
34
-
-
60649089997
-
Cancer metastasis is accelerated through immunosuppression during snail-induced emt of cancer cells
-
Kudo-Saito C, Shirako H, Takeuchi T, Kawakami Y: Cancer metastasis is accelerated through immunosuppression during snail-induced emt of cancer cells. Cancer Cell 2009;15:195-206.
-
(2009)
Cancer Cell
, vol.15
, pp. 195-206
-
-
Kudo-Saito, C.1
Shirako, H.2
Takeuchi, T.3
Kawakami, Y.4
-
35
-
-
33745186178
-
The signaling and biological implications of fak overexpression in cancer
-
Siesser PM, Hanks SK: The signaling and biological implications of fak overexpression in cancer. Clin Cancer Res 2006;12:3233-3237.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3233-3237
-
-
Siesser, P.M.1
Hanks, S.K.2
|