Exposure time-dependent effects on the relative potencies and additivity of PAHs in the Ah receptor-based H4IIE-luc bioassay

Environmental Toxicology and Chemistry

Volumn 31, Issue 5, 2012, Pages 1149-1157

  Larsson, Maria ^a   Orbe, Dan ^a   Engwall, Magnus ^a  

^a ÖREBRO UNIVERSITY   (Sweden)

Author keywords

AhR agonists; Concentration addition; Mixture toxicity; PAHs; Relative potencies

Indexed keywords

AHR AGONISTS; CONCENTRATION-ADDITION; MIXTURE TOXICITY; PAHS; RELATIVE POTENCIES;

BIOASSAY; MIXTURES; TOXICITY;

POLYCYCLIC AROMATIC HYDROCARBONS;

AROMATIC HYDROCARBON RECEPTOR; BENZ[A]ANTHRACENE; BENZO[A]PYRENE; BENZO[B]FLUORANTHENE; BENZO[E]PYRENE; BENZO[GHI]PERYLENE; BENZO[K]FLUORANTHENE; CHRYSENE; DIBENZ[A,H]ANTHRACENE; EBERCONAZOLE; FLUORANTHENE; INDENO[1,2,3 CD]PYRENE; LUCIFERASE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE;

BIOASSAY; CONCENTRATION (COMPOSITION); NUMERICAL MODEL; PAH; POLLUTION EFFECT; POLLUTION EXPOSURE; RISK ASSESSMENT; TIME DEPENDENT BEHAVIOR; TOXICITY;

ANIMAL CELL; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG POTENCY; EXPOSURE; H4IIE LUC BIOASSAY; NONHUMAN; PRIORITY JOURNAL; RAT; RELATIVE POTENCY; RISK ASSESSMENT; TOXICITY TESTING;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE; COMPLEX MIXTURES; LUCIFERASES; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RECEPTORS, ARYL HYDROCARBON; TIME FACTORS; TOXICITY TESTS;

EID: 84859877788     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.1776     Document Type: Article

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