Specificity of botulinum protease for human VAMP family proteins

Microbiology and Immunology

Volumn 56, Issue 4, 2012, Pages 245-253

  Yamamoto, Hideyuki ^a   Ida, Tomoaki ^a   Tsutsuki, Hiroyasu ^b   Mori, Masatoshi ^c   Matsumoto, Tomoko ^d   Kohda, Tomoko ^a   Mukamoto, Masafumi ^a   Goshima, Naoki ^d   Kozaki, Shunji ^a   Ihara, Hideshi ^a  

^a Osaka Prefecture University   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c Japan Biological Informatics Consortium   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Botulinum neurotoxin light chain; Proteolysis; Substrate specificity; VAMP proteins

Indexed keywords

BACTERIAL TOXIN; BOTULINUM NEUROTOXIN LIGHT CHAIN; BOTULINUM NEUROTOXIN LIGHT CHAIN B; BOTULINUM NEUROTOXIN LIGHT CHAIN F; BOTULINUM TOXIN; CELLUBREVIN; COMPLEMENTARY DNA; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOBREVIN 1; SYNAPTOBREVIN 2; UNCLASSIFIED DRUG;

ANTIBIOSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; HUMAN; IN VITRO STUDY; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PROTEIN CLEAVAGE; SEQUENCE ANALYSIS; WILD TYPE;

BOTULINUM TOXINS; CLOSTRIDIUM BOTULINUM; HUMANS; PROTEOLYSIS; R-SNARE PROTEINS; SUBSTRATE SPECIFICITY;

EUKARYOTA;

EID: 84859844136     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2012.00434.x     Document Type: Article

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