Silencing of VAMP3 inhibits cell migration and integrin-mediated adhesion

Biochemical and Biophysical Research Communications

Volumn 380, Issue 1, 2009, Pages 65-70

  Luftman, Kevin ^a   Hasan, Nazarul ^a   Day, Paul ^a   Hardee, Deborah ^a   Hu, Chuan ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Cell adhesion; Cell migration; Integrin; SNARE; VAMP3

Indexed keywords

BETA1 INTEGRIN; CELLUBREVIN; COLLAGEN; FIBRONECTIN; LAMININ; SMALL INTERFERING RNA;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; EXOCYTOSIS; GENE SILENCING; HUMAN; HUMAN CELL; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

ANTIGENS, CD29; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMOTAXIS; GENE SILENCING; HUMANS; LAMININ; PROTEIN TRANSPORT; RNA, SMALL INTERFERING; VESICLE-ASSOCIATED MEMBRANE PROTEIN 3;

EID: 59649096973     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.01.036     Document Type: Article

References (33)

1. Ridley A.J., Schwartz M.A., Burridge K., Firtel R.A., Ginsberg M.H., Borisy G., Parsons J.T., and Horwitz A.R. Cell migration: integrating signals from front to back. Science 302 (2003) 1704-1709
2. Hynes R.O. Integrins: bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
3. Bretscher M.S. Getting membrane flow and the cytoskeleton to cooperate in moving cells. Cell 87 (1996) 601-606
4. Caswell P.T., and Norman J.C. Integrin trafficking and the control of cell migration. Traffic 7 (2006) 14-21
5. Lenter M., and Vestweber D. The integrin chains beta 1 and alpha 6 associate with the chaperone calnexin prior to integrin assembly. J. Biol. Chem. 269 (1994) 12263-12268
6. Rigot V., Andre F., Lehmann M., Lissitzky J.C., Marvaldi J., and Luis J. Biogenesis of alpha6beta4 integrin in a human colonic adenocarcinoma cell line involvement of calnexin. Eur. J. Biochem. 261 (1999) 659-666
7. Lawson M.A., and Maxfield F.R. Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 377 (1995) 75-79
8. Laukaitis C.M., Webb D.J., Donais K., and Horwitz A.F. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J. Cell Biol. 153 (2001) 1427-1440
9. Woods A.J., White D.P., Caswell P.T., and Norman J.C. PKD1/PKCmu promotes alphavbeta3 integrin recycling and delivery to nascent focal adhesions. EMBO J. 23 (2004) 2531-2543
10. Ng T., Shima D., Squire A., Bastiaens P.I., Gschmeissner S., Humphries M.J., and Parker P.J. PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic. EMBO J. 18 (1999) 3909-3923
11. Ivaska J., Whelan R.D., Watson R., and Parker P.J. PKC epsilon controls the traffic of beta1 integrins in motile cells. EMBO J. 21 (2002) 3608-3619
12. Caswell P.T., Spence H.J., Parsons M., White D.P., Clark K., Cheng K.W., Mills G.B., Humphries M.J., Messent A.J., Anderson K.I., McCaffrey M.W., Ozanne B.W., and Norman J.C. Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev. Cell 13 (2007) 496-510
13. Sollner T., Whiteheart S.W., Brunner M., Erdjument-Bromage H., Geromanos S., Tempst P., and Rothman J.E. SNAP receptors implicated in vesicle targeting and fusion. Nature 362 (1993) 318-324
14. Rothman J.E. Mechanisms of intracellular protein transport, Nature 372 (1994) 55-63
15. Jahn R., and Scheller R.H. SNAREs - engines for membrane fusion. Nat. Rev. Mol. Cell Biol. 7 (2006) 631-643
16. Sutton R.B., Fasshauer D., Jahn R., and Brunger A.T. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution. Nature 395 (1998) 347-353
17. Weber T., Zemelman B.V., McNew J.A., Westermann B., Gmachl M., Parlati F., Sollner T.H., and Rothman J.E. SNAREpins: minimal machinery for membrane fusion. Cell 92 (1998) 759-772
18. McNew J.A., Weber T., Parlati F., Johnston R.J., Melia T.J., Sollner T.H., and Rothman J.E. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J. Cell Biol. 150 (2000) 105-117
19. Hu C., Ahmed M., Melia T.J., Sollner T.H., Mayer T., and Rothman J.E. Fusion of cells by flipped SNAREs. Science 300 (2003) 1745-1749
20. McMahon H.T., Ushkaryov Y.A., Edelmann L., Link E., Binz T., Niemann H., Jahn R., and Sudhof T.C. Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein. Nature 364 (1993) 346-349
21. Polgar J., Chung S.H., and Reed G.L. Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. Blood 100 (2002) 1081-1083
22. Galli T., Chilcote T., Mundigl O., Binz T., Niemann H., and De Camilli P. Tetanus toxin-mediated cleavage of cellubrevin impairs exocytosis of transferrin receptor-containing vesicles in CHO cells. J. Cell Biol. 125 (1994) 1015-1024
23. Skalski M., and Coppolino M.G. SNARE-mediated trafficking of alpha5beta1 integrin is required for spreading in CHO cells. Biochem. Biophys. Res. Commun. 335 (2005) 1199-1210
24. Tayeb M.A., Skalski M., Cha M.C., Kean M.J., Scaife M., and Coppolino M.G. Inhibition of SNARE-mediated membrane traffic impairs cell migration. Exp. Cell Res. 305 (2005) 63-73
25. Proux-Gillardeaux V., Gavard J., Irinopoulou T., Mege R.M., and Galli T. Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion. Proc. Natl. Acad. Sci. USA 102 (2005) 6362-6367
26. Powelka A.M., Sun J., Li J., Gao M., Shaw L.M., Sonnenberg A., and Hsu V.W. Stimulation-dependent recycling of integrin beta1 regulated by ARF6 and Rab11. Traffic 5 (2004) 20-36
27. Stahle M., Veit C., Bachfischer U., Schierling K., Skripczynski B., Hall A., Gierschik P., and Giehl K. Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J. Cell Sci. 116 (2003) 3835-3846
28. Vogelmann R., Nguyen-Tat M.D., Giehl K., Adler G., Wedlich D., and Menke A. TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN. J. Cell Sci. 118 (2005) 4901-4912
29. Sakai T., Peyruchaud O., Fassler R., and Mosher D.F. Restoration of beta1A integrins is required for lysophosphatidic acid-induced migration of beta1-null mouse fibroblastic cells. J. Biol. Chem. 273 (1998) 19378-19382
30. V. Rigot, M. Lehmann, F. Andre, N. Daemi, J. Marvaldi, J. Luis, Integrin ligation and PKC activation are required for migration of colon carcinoma cells, J. Cell Sci. 111 (Pt. 20) (1998) 3119-3127.
31. Ridley A.J. Rho proteins: linking signaling with membrane trafficking. Traffic 2 (2001) 303-310
32. Bretscher M.S. Distribution of receptors for transferrin and low density lipoprotein on the surface of giant HeLa cells. Proc. Natl. Acad. Sci. USA 80 (1983) 454-458
33. Bravo-Cordero J.J., Marrero-Diaz R., Megias D., Genis L., Garcia-Grande A., Garcia M.A., Arroyo A.G., and Montoya M.C. MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J. 26 (2007) 1499-1510