Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 9, 2012, Pages 3261-3264

  Chen, Shang Ke ^a   Zhao, Peng ^a   Shao, Yong Xian ^a   Li, Zhe ^a   Zhang, Cuixian ^b   Liu, Peiqing ^a   He, Xixin ^b   Luo, Hai Bin ^a   Hu, Xiaopeng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Asthma; Inhibition; Kinetics analysis; Molecular docking; Molecular dynamics simulations; Moracin M; PDE4

Indexed keywords

MORACIN C; MORACIN M; PHOSPHODIESTERASE; PHOSPHODIESTERASE IV B2; PHOSPHODIESTERASE IV D2; PHOSPHODIESTERASE IV INHIBITOR; PHOSPHODIESTERASE IX A2; PHOSPHODIESTERASE V; PHOSPHODIESTERASE V A1; UNCLASSIFIED DRUG;

ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MORUS ALBA; QUALITATIVE ANALYSIS;

BENZOFURANS; COMPUTER SIMULATION; DRUGS, CHINESE HERBAL; INHIBITORY CONCENTRATION 50; KINETICS; MOLECULAR DYNAMICS SIMULATION; MORUS; PHOSPHODIESTERASE 4 INHIBITORS; PLANT EXTRACTS; PROTEIN BINDING; RESORCINOLS;

MORUS ALBA;

EID: 84859813759     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.03.026     Document Type: Article

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