메뉴 건너뛰기




Volumn 2 1, Issue , 2008, Pages 89-97

The emerging role of eicosapentaenoic acid as an important psychoactive natural product: Some answers but a lot more questions

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84859798711     PISSN: None     EISSN: 11786353     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (91)
  • 4
    • 0033665278 scopus 로고    scopus 로고
    • Eicosapentaenoic acid (EPA): an antiinfl ammatory omega-3 fat
    • Babcock, T., Helton, W.S. and Espat, N.J. 2000. Eicosapentaenoic acid (EPA): an antiinfl ammatory omega-3 fat. Nutrition, 16:1116-8.
    • (2000) Nutrition , vol.16 , pp. 1116-1118
    • Babcock, T.1    Helton, W.S.2    Espat, N.J.3
  • 5
    • 33749154105 scopus 로고    scopus 로고
    • Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review
    • Balk, E.M., Lichtenstein, A.H., Chung, M., Kupelnick, B., Chew, P. and Lau, J. 2006. Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review. Atherosclerosis, 189:19-30.
    • (2006) Atherosclerosis , vol.189 , pp. 19-30
    • Balk, E.M.1    Lichtenstein, A.H.2    Chung, M.3    Kupelnick, B.4    Chew, P.5    Lau, J.6
  • 6
    • 41449110020 scopus 로고    scopus 로고
    • Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications
    • Bays, H.E., Tighe, A.P., Sadovsky, R. and Davidson, M.H. 2008. Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications. Expert Rev. Cardiovasc. Ther., 6:391-409.
    • (2008) Expert Rev. Cardiovasc. Ther. , vol.6 , pp. 391-409
    • Bays, H.E.1    Tighe, A.P.2    Sadovsky, R.3    Davidson, M.H.4
  • 7
    • 43449136454 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation and total homocysteine levels in end-stage renal disease patients
    • Beavers, K.M., Beavers, D.P., Bowden, R.G., Wilson, R.L. and Gentile, M. 2008. Omega-3 fatty acid supplementation and total homocysteine levels in end-stage renal disease patients. Nephrology (Carlton), 13:284-8.
    • (2008) Nephrology (Carlton) , vol.13 , pp. 284-288
    • Beavers, K.M.1    Beavers, D.P.2    Bowden, R.G.3    Wilson, R.L.4    Gentile, M.5
  • 8
    • 0031815337 scopus 로고    scopus 로고
    • Effector pathway-dependent relative effi cacy at serotonin type 2A and 2C receptors: evidence for agonist-directed traffi cking of receptor stimulus
    • Berg, K.A., Maayani, S., Goldfarb, J., Scaramellini, C., Leff, P. and Clarke, W.P. 1998. Effector pathway-dependent relative effi cacy at serotonin type 2A and 2C receptors: evidence for agonist-directed traffi cking of receptor stimulus. Mol. Pharmacol., 54:94-104.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 94-104
    • Berg, K.A.1    Maayani, S.2    Goldfarb, J.3    Scaramellini, C.4    Leff, P.5    Clarke, W.P.6
  • 9
    • 0033214097 scopus 로고    scopus 로고
    • In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation
    • Berge, R.K., Masen, L., Vaagenes, H., Tronstad, K.J., Gottlicher, M. and Rustan, A.C. 1999. In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation. Biochem. J., 343:191-7.
    • (1999) Biochem. J. , vol.343 , pp. 191-197
    • Berge, R.K.1    Masen, L.2    Vaagenes, H.3    Tronstad, K.J.4    Gottlicher, M.5    Rustan, A.C.6
  • 10
    • 51349137876 scopus 로고    scopus 로고
    • Cancer Lett. Multi-targeted therapy of cancer by omega-3 fatty acids
    • Berquin, I.M., Edwards, I.J. and Chen, Y.Q. 2008. Cancer Lett. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Lett., 269:363-77.
    • (2008) Cancer Lett , vol.269 , pp. 363-377
    • Berquin, I.M.1    Edwards, I.J.2    Chen, Y.Q.3
  • 14
    • 38749137406 scopus 로고    scopus 로고
    • Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers
    • Buydens-Branchey, L., Branchey, M. and Hibbeln, J.R. 2008. Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers. Prog. Neuropsychopharmacol. Biol. Psychiatry, 32:568-75.
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , pp. 568-575
    • Buydens-Branchey, L.1    Branchey, M.2    Hibbeln, J.R.3
  • 15
    • 36849066352 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: molecular mechanisms involved
    • Calviello, G., Serini, S. and Piccioni, E. 2007. n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: molecular mechanisms involved. Curr. Med. Chem., 14:3059-69.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 3059-3069
    • Calviello, G.1    Serini, S.2    Piccioni, E.3
  • 16
    • 48849086545 scopus 로고    scopus 로고
    • Neurotrophins in depression and antidepressant effects
    • Castrén, E. and Rantamäki, T. 2008. Neurotrophins in depression and antidepressant effects. Novartis Found Symp., 289:43-52.
    • (2008) Novartis Found Symp , vol.289 , pp. 43-52
    • Castrén, E.1    Rantamäki, T.2
  • 17
    • 34250640687 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults
    • Conklin, S.M., Gianaros, P.J., Brown, S.M., Yao, J.K., Hariri, A.R., Manuck, S.B. and Muldoon, M.F. 2007. Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults. Neurosci. Lett., 421:209-12.
    • (2007) Neurosci. Lett. , vol.421 , pp. 209-212
    • Conklin, S.M.1    Gianaros, P.J.2    Brown, S.M.3    Yao, J.K.4    Hariri, A.R.5    Manuck, S.B.6    Muldoon, M.F.7
  • 18
    • 84865159895 scopus 로고    scopus 로고
    • The Eicosanoids London, U.K: Wiley. Davis, J.D. and Tremont
    • Curtis-Prior, P. 2004. The Eicosanoids London, U.K: Wiley. Davis, J.D. and Tremont, G. Neuropsychiatric aspects of hypothyroidism and treatment reversibility. Minerva. Endocrinol., 32:49-65.
    • (2004) Minerva. Endocrinol. , vol.32 , pp. 49-65
    • Curtis-Prior, P.1
  • 19
    • 0037131324 scopus 로고    scopus 로고
    • The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts
    • Diaz, O., Berquand, A., Dubois, M., Di Agostino, S., Sette, C., Bourgoin, S., Lagarde, M., Nemoz, G. and Prigent, A.F. 2002. The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts. J. Biol. Chem., 277:39368-7.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39368-39377
    • Diaz, O.1    Berquand, A.2    Dubois, M.3    Di Agostino, S.4    Sette, C.5    Bourgoin, S.6    Lagarde, M.7    Nemoz, G.8    Prigent, A.F.9
  • 20
    • 0036777552 scopus 로고    scopus 로고
    • Fatty acid augmentation of the cardiac slowly activating delayed rectifi er current (IKs) is conferred by hminK
    • Doolan, G.K., Panchal, R.G., Fonnes, E.L., Clarke, A.L., Williams, D.A. and Petrou, S. 2002. Fatty acid augmentation of the cardiac slowly activating delayed rectifi er current (IKs) is conferred by hminK. FASEB J., 16:1662-4.
    • (2002) FASEB J , vol.16 , pp. 1662-1664
    • Doolan, G.K.1    Panchal, R.G.2    Fonnes, E.L.3    Clarke, A.L.4    Williams, D.A.5    Petrou, S.6
  • 21
    • 33646161454 scopus 로고    scopus 로고
    • Fatty acids differentially affect serotonin receptor and transporter binding in the rat brain
    • du Bois, T.M., Deng, C., Bell, W. and Huang, X.F. 2006. Fatty acids differentially affect serotonin receptor and transporter binding in the rat brain. Neuroscience, 139:1397-403.
    • (2006) Neuroscience , vol.139 , pp. 1397-1403
    • du Bois, T.M.1    Deng, C.2    Bell, W.3    Huang, X.F.4
  • 22
    • 33846633240 scopus 로고    scopus 로고
    • Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B. glutamate receptor subunits in rat forebrain
    • Dyall, S.C., Michael, G.J., Whelpton, R., Scott, A.G. and Michael-Titus, A.T. 2007. Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B. glutamate receptor subunits in rat forebrain. Neurobiol. Aging, 28:424-39.
    • (2007) Neurobiol. Aging , vol.28 , pp. 424-439
    • Dyall, S.C.1    Michael, G.J.2    Whelpton, R.3    Scott, A.G.4    Michael-Titus, A.T.5
  • 23
    • 0028068555 scopus 로고
    • Dietary linoleic acid infl uences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males
    • Emken, E.A., Adlof, R.O. and Gulley, R.M. 1994. Dietary linoleic acid infl uences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males. Biochim. Biophys. Acta., 1213:277-88.
    • (1994) Biochim. Biophys. Acta. , vol.1213 , pp. 277-288
    • Emken, E.A.1    Adlof, R.O.2    Gulley, R.M.3
  • 24
    • 0031278302 scopus 로고    scopus 로고
    • Effects of omega 3 fatty acids on receptor tyrosine kinase and PLC activities in EMT6 cells
    • Estes, K.C., Rose, B.T., Speck, J.J., Nutter, M.L. and Reitz, R.C. 1997. Effects of omega 3 fatty acids on receptor tyrosine kinase and PLC activities in EMT6 cells. J. Lipid Mediat. Cell Signal, 17:81-96.
    • (1997) J. Lipid Mediat. Cell Signal , vol.17 , pp. 81-96
    • Estes, K.C.1    Rose, B.T.2    Speck, J.J.3    Nutter, M.L.4    Reitz, R.C.5
  • 25
    • 0035013845 scopus 로고    scopus 로고
    • Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components
    • Evans, K.L., Cropper, J.D., Berg, K.A. and Clarke, W.P. 2001. Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components. J. Pharmacol. Exp. Ther., 297:1025-35.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 1025-1035
    • Evans, K.L.1    Cropper, J.D.2    Berg, K.A.3    Clarke, W.P.4
  • 26
    • 29644443167 scopus 로고    scopus 로고
    • Efficacy of ethyleicosapentaenoic acid in bipolar depression: randomised double-blind placebo-controlled study
    • Frangou, S., Lewis, M. and McCrone, P. 2006. Efficacy of ethyleicosapentaenoic acid in bipolar depression: randomised double-blind placebo-controlled study. Br. J. Psychiatry, 188:46-50.
    • (2006) Br. J. Psychiatry , vol.188 , pp. 46-50
    • Frangou, S.1    Lewis, M.2    McCrone, P.3
  • 28
    • 53749101144 scopus 로고    scopus 로고
    • Neuroimaging genetics: new perspectives in research on major depression?
    • press
    • Frodl, T., Möller, H.J. and Meisenzahl, E. 2008. Neuroimaging genetics: new perspectives in research on major depression? Acta. Psychiatr Scand, in press.
    • (2008) Acta. Psychiatr Scand
    • Frodl, T.1    Möller, H.J.2    Meisenzahl, E.3
  • 29
    • 4143092559 scopus 로고    scopus 로고
    • Chronic carbamazepine selectively downregulates cytosolic phospholipase A2 expression and cyclooxygenase activity in rat brain
    • Ghelardoni, S., Tomita, Y.A., Bell, J.M., Rapoport, S.I. and Bosetti, F. 2004. Chronic carbamazepine selectively downregulates cytosolic phospholipase A2 expression and cyclooxygenase activity in rat brain. Biol. Psychiatry, 56:248-54.
    • (2004) Biol. Psychiatry , vol.56 , pp. 248-254
    • Ghelardoni, S.1    Tomita, Y.A.2    Bell, J.M.3    Rapoport, S.I.4    Bosetti, F.5
  • 31
    • 0033862174 scopus 로고    scopus 로고
    • Effect of moderate amounts of dietary fi sh oil on neutrophil lipid composition and function
    • Healy, D.A., Wallace, F.A., Miles, E.A., Calder, P.C. and Newsholm, P. 2000. Effect of moderate amounts of dietary fi sh oil on neutrophil lipid composition and function. Lipids, 35:763-8.
    • (2000) Lipids , vol.35 , pp. 763-768
    • Healy, D.A.1    Wallace, F.A.2    Miles, E.A.3    Calder, P.C.4    Newsholm, P.5
  • 33
    • 0035991243 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and arachidonic acid: collaboration and not antagonism is the key to biological understanding
    • Horrobin, D.F., Jenkins, K., Bennett, C.N. and Christie, W.W. 2002. Eicosapentaenoic acid and arachidonic acid: collaboration and not antagonism is the key to biological understanding. Prostaglandins Leukot Essent Fatty Acids, 66:83-90.
    • (2002) Prostaglandins Leukot Essent Fatty Acids , vol.66 , pp. 83-90
    • Horrobin, D.F.1    Jenkins, K.2    Bennett, C.N.3    Christie, W.W.4
  • 34
    • 34247275851 scopus 로고    scopus 로고
    • Neuropsychiatric consequences of cardiovascular medications
    • Huffman, J.C. and Stern, T.A. 2007. Neuropsychiatric consequences of cardiovascular medications. Dialogues Clin. Neurosci., 9:29-45.
    • (2007) Dialogues Clin. Neurosci. , vol.9 , pp. 29-45
    • Huffman, J.C.1    Stern, T.A.2
  • 35
    • 39049148835 scopus 로고    scopus 로고
    • Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fl uoxetine, separately and in combination, in major depressive disorder
    • Jazayeri, S., Tehrani-Doost, M., Keshavarz, S.A., Hosseini, M., Djazayery, A., Amini, H., Jalali, M. and Peet, M. 2008. Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fl uoxetine, separately and in combination, in major depressive disorder. Aust. N. Z. J. Psychiatry, 42:192-8.
    • (2008) Aust. N. Z. J. Psychiatry , vol.42 , pp. 192-198
    • Jazayeri, S.1    Tehrani-Doost, M.2    Keshavarz, S.A.3    Hosseini, M.4    Djazayery, A.5    Amini, H.6    Jalali, M.7    Peet, M.8
  • 36
    • 60449088923 scopus 로고    scopus 로고
    • Omega-3/Omega-6 Fatty Acids for Attention Defi cit Hyperactivity Disorder: A Randomized Placebo-Controlled Trial in Children and Adolescents
    • press
    • Johnson, M., Ostlund, S., Fransson, G., Kadesjö, B. and Gillberg, C. Omega-3/Omega-6 Fatty Acids for Attention Defi cit Hyperactivity Disorder: A Randomized Placebo-Controlled Trial in Children and Adolescents. J. Atten. Disord, in press.
    • J. Atten. Disord
    • Johnson, M.1    Ostlund, S.2    Fransson, G.3    Kadesjö, B.4    Gillberg, C.5
  • 37
    • 0038678733 scopus 로고    scopus 로고
    • Peroxidation of docosahexaenoic acid is responsible for its effects on I TO and I SS in rat ventricular myocytes
    • Jude, S., Bedut, S., Roger, S., Pinault, M., Champeroux, P., White, E. and Le Guennec, J.Y. 2003. Peroxidation of docosahexaenoic acid is responsible for its effects on I TO and I SS in rat ventricular myocytes. Br. J. Pharmacol., 139:816-22.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 816-822
    • Jude, S.1    Bedut, S.2    Roger, S.3    Pinault, M.4    Champeroux, P.5    White, E.6    Le Guennec, J.Y.7
  • 38
    • 1842481571 scopus 로고    scopus 로고
    • Structural MRI changes of the brain in depression
    • Kanner, A.M. 2004. Structural MRI changes of the brain in depression. Clin. EEG Neurosci., 35:46-52.
    • (2004) Clin. EEG Neurosci. , vol.35 , pp. 46-52
    • Kanner, A.M.1
  • 40
    • 43749101147 scopus 로고    scopus 로고
    • Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression
    • Kim, J.M., Stewart, R., Kim, S.W., Yang, S.J., Shin, I.S. and Yoon, J.S. 2008. Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression. Br. J. Psychiatry, 192:268-74.
    • (2008) Br. J. Psychiatry , vol.192 , pp. 268-274
    • Kim, J.M.1    Stewart, R.2    Kim, S.W.3    Yang, S.J.4    Shin, I.S.5    Yoon, J.S.6
  • 41
    • 51649111510 scopus 로고    scopus 로고
    • Altered expression of key dopaminergic regulatory proteins in the postnatal brain following perinatal n-3 fatty acid dietary deficiency
    • Kuperstein, F., Eilam, R. and Yavin, E. 2008. Altered expression of key dopaminergic regulatory proteins in the postnatal brain following perinatal n-3 fatty acid dietary deficiency. J. Neurochem., 106:662-71.
    • (2008) J. Neurochem. , vol.106 , pp. 662-671
    • Kuperstein, F.1    Eilam, R.2    Yavin, E.3
  • 42
    • 0035698468 scopus 로고    scopus 로고
    • The electrophysiologic basis for the antiarrhythmic and anticonvulsant effects of n-3 polyunsaturated fatty acids: heart and brain
    • Leaf, A. 2001. The electrophysiologic basis for the antiarrhythmic and anticonvulsant effects of n-3 polyunsaturated fatty acids: heart and brain. Lipids, 36 (Suppl):S107-10.
    • (2001) Lipids , vol.36 , Issue.SUPPL.
    • Leaf, A.1
  • 43
    • 33845362024 scopus 로고    scopus 로고
    • Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat
    • Lee, H.J., Rao, J.S., Ertley, R.N., Chang, L., Rapoport, S.I. and Bazinet, R.P. 2007. Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology (Berl), 190:103-15.
    • (2007) Psychopharmacology (Berl) , vol.190 , pp. 103-115
    • Lee, H.J.1    Rao, J.S.2    Ertley, R.N.3    Chang, L.4    Rapoport, S.I.5    Bazinet, R.P.6
  • 46
  • 47
    • 34548315737 scopus 로고    scopus 로고
    • A meta-analytic review of double-blind, placebo-controlled trials of antidepressant effi cacy of omega-3 fatty acids
    • Lin, P.Y. and Su, K.P. 2007. A meta-analytic review of double-blind, placebo-controlled trials of antidepressant effi cacy of omega-3 fatty acids. J. Clin. Psychiatry, 68:1056-61.
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 1056-1061
    • Lin, P.Y.1    Su, K.P.2
  • 48
    • 48049084135 scopus 로고    scopus 로고
    • The cytokine hypothesis of depression: infl ammation, oxidative and nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression
    • Maes, M. 2008. The cytokine hypothesis of depression: infl ammation, oxidative and nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression. Neuro. Endocrinol. Lett., 29:287-91.
    • (2008) Neuro. Endocrinol. Lett. , vol.29 , pp. 287-291
    • Maes, M.1
  • 49
    • 0037844785 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression
    • Marangell, L.B., Martinez, J.M., Zboyan, H.A., Kertz, B., Kim, H.F. and Puryear, L.J. 2003. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. J. Psychiatry, 160:996-8.
    • (2003) J. Psychiatry , vol.160 , pp. 996-998
    • Marangell, L.B.1    Martinez, J.M.2    Zboyan, H.A.3    Kertz, B.4    Kim, H.F.5    Puryear, L.J.6
  • 50
    • 33846230027 scopus 로고    scopus 로고
    • TRPV1 is a novel target for omega-3 polyunsaturated fatty acids
    • Matta, J.A., Miyares, R.L. and Ahern, G.P. 2007. TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. J. Physiol., 578:397-411.
    • (2007) J. Physiol. , vol.578 , pp. 397-411
    • Matta, J.A.1    Miyares, R.L.2    Ahern, G.P.3
  • 51
    • 34250163939 scopus 로고    scopus 로고
    • Selective defi cits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder
    • McNamara, R.K., Hahn, C.G., Jandacek, R., Rider, T., Tso, P., Stanford, K.E. and Richtand, N.M. 2007. Selective defi cits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder. Biol. Psychiatry, 62:17-24.
    • (2007) Biol. Psychiatry , vol.62 , pp. 17-24
    • McNamara, R.K.1    Hahn, C.G.2    Jandacek, R.3    Rider, T.4    Tso, P.5    Stanford, K.E.6    Richtand, N.M.7
  • 52
    • 50449101908 scopus 로고    scopus 로고
    • Defi cits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder
    • McNamara, R.K., Jandacek, R., Rider, T., Tso, P., Stanford, K.E., Hahn, C.G. and Richtand, N. M. 2008. Defi cits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. Psychiatry Res., 160:285-99.
    • (2008) Psychiatry Res , vol.160 , pp. 285-299
    • McNamara, R.K.1    Jandacek, R.2    Rider, T.3    Tso, P.4    Stanford, K.E.5    Hahn, C.G.6    Richtand, N.M.7
  • 53
    • 33748983343 scopus 로고    scopus 로고
    • Modulation of phosphoinositideprotein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness
    • McNamara, R.K., Ostrander, M., Abplanalp, W., Richtand, N.M., Benoit, S.C. and Clegg, D.J. 2006. Modulation of phosphoinositideprotein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness. Prostaglandins Leukot Essent Fatty Acids, 75:237-57.
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.75 , pp. 237-257
    • McNamara, R.K.1    Ostrander, M.2    Abplanalp, W.3    Richtand, N.M.4    Benoit, S.C.5    Clegg, D.J.6
  • 54
    • 0034740264 scopus 로고    scopus 로고
    • Acute and chronic toxicity study of fi sh oil and garlic combination
    • Morcos, N.C. and Camilo, K. 2001. Acute and chronic toxicity study of fi sh oil and garlic combination. Int. J. Vitam. Nutr. Res., 71:306-12.
    • (2001) Int. J. Vitam. Nutr. Res. , vol.71 , pp. 306-312
    • Morcos, N.C.1    Camilo, K.2
  • 55
    • 37349103067 scopus 로고    scopus 로고
    • Dietary intake of folate, other B. vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults
    • Murakami, K., Mizoue, T., Sasaki, S., Ohta, M., Sato, M., Matsushita, Y. and Mishima, N. 2008. Dietary intake of folate, other B. vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults. Nutrition, 24:140-7.
    • (2008) Nutrition , vol.24 , pp. 140-147
    • Murakami, K.1    Mizoue, T.2    Sasaki, S.3    Ohta, M.4    Sato, M.5    Matsushita, Y.6    Mishima, N.7
  • 56
    • 0036190807 scopus 로고    scopus 로고
    • Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder
    • Nemets, B., Stahl, Z. and Belmaker, R.H. 2002. Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder. Am. J. Psychiatry, 159:477-9.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 477-479
    • Nemets, B.1    Stahl, Z.2    Belmaker, R.H.3
  • 57
    • 85047698720 scopus 로고    scopus 로고
    • Omega-3 treatment of childhood depression: a controlled, double-blind pilot study
    • Nemets, H., Nemets, B., Apter, A., Bracha, Z. and Belmaker, R.H. 2006. Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. Am. J. Psychiatry, 163:1098-100.
    • (2006) Am. J. Psychiatry , vol.163 , pp. 1098-1100
    • Nemets, H.1    Nemets, B.2    Apter, A.3    Bracha, Z.4    Belmaker, R.H.5
  • 58
    • 20444480501 scopus 로고    scopus 로고
    • Differential effects of eicosapentaenoic and docosahexaenoic acids upon oxidant-stimulated release and uptake of arachidonic acid in human lymphoma U937 cells
    • Obajimi, O., Black, K.D., MacDonald, D.J., Boyle, R.M., Glen, I. and Ross, B.M. 2005. Differential effects of eicosapentaenoic and docosahexaenoic acids upon oxidant-stimulated release and uptake of arachidonic acid in human lymphoma U937 cells. Pharmacol. Res., 52:183-91.
    • (2005) Pharmacol. Res. , vol.52 , pp. 183-191
    • Obajimi, O.1    Black, K.D.2    MacDonald, D.J.3    Boyle, R.M.4    Glen, I.5    Ross, B.M.6
  • 59
    • 0036790628 scopus 로고    scopus 로고
    • A dose-ranging study of the effects of ethyl-eicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs
    • Peet, M. and Horrobin, D.F. 2002. A dose-ranging study of the effects of ethyl-eicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Arch. Gen Psychiatry, 59:913-9.
    • (2002) Arch. Gen Psychiatry , vol.59 , pp. 913-919
    • Peet, M.1    Horrobin, D.F.2
  • 60
    • 0023567276 scopus 로고
    • Ingestion of fi sh oil or a derived n-3 fatty acid concentrate containing aicosapentaenoic acid (EPA) affects fatty acid compositions of individual phospholipids of rat brain, sciatic nerve and retina
    • Philbrick, D-J., Mahadevappa, V.G., Ackman, R.G. and Holub, B.J. 1987. Ingestion of fi sh oil or a derived n-3 fatty acid concentrate containing aicosapentaenoic acid (EPA) affects fatty acid compositions of individual phospholipids of rat brain, sciatic nerve and retina. J. Nutr., 117:1663-70.
    • (1987) J. Nutr. , vol.117 , pp. 1663-1670
    • Philbrick, D.-J.1    Mahadevappa, V.G.2    Ackman, R.G.3    Holub, B.J.4
  • 62
    • 0025870668 scopus 로고
    • Dopamine activation of the arachidonic acid cascade as a basis for D1/D2 receptor synergism
    • Piomelli, D., Pilon, C., Giros, B., Sokoloff, P., Martres, M.P. and Schwartz, J.C. 1991. Dopamine activation of the arachidonic acid cascade as a basis for D1/D2 receptor synergism. Nature, 353:164-7.
    • (1991) Nature , vol.353 , pp. 164-167
    • Piomelli, D.1    Pilon, C.2    Giros, B.3    Sokoloff, P.4    Martres, M.P.5    Schwartz, J.C.6
  • 63
    • 0033980578 scopus 로고    scopus 로고
    • Eicosapentaenoic acid treatment in schizophrenia associated with symptom remission, normalisation of blood fatty acids, reduced neuronal membrane phospholipid turnover and structural brain changes
    • Puri, B.K., Richardson, A.J., Horrobin, D.F., Easton, T., Oatridge, A., Hajnal, J.V. and Bydder G.M. 2000. Eicosapentaenoic acid treatment in schizophrenia associated with symptom remission, normalisation of blood fatty acids, reduced neuronal membrane phospholipid turnover and structural brain changes. Int. J. Clin. Pract., 54:57-63.
    • (2000) Int. J. Clin. Pract. , vol.54 , pp. 57-63
    • Puri, B.K.1    Richardson, A.J.2    Horrobin, D.F.3    Easton, T.4    Oatridge, A.5    Hajnal, J.V.6    Bydder, G.M.7
  • 64
    • 0041421000 scopus 로고    scopus 로고
    • Imaging brain phospholipase A2-mediated signal transduction in response to acute fl uoxetine administration in unanesthetized rats
    • Qu, Y., Chang, L., Klaff, J., Seemann, R. and Rapoport, S.I. 2003. Imaging brain phospholipase A2-mediated signal transduction in response to acute fl uoxetine administration in unanesthetized rats. Neuropsychopharmacology, 28:1219-26.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1219-1226
    • Qu, Y.1    Chang, L.2    Klaff, J.3    Seemann, R.4    Rapoport, S.I.5
  • 65
    • 33845775752 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism
    • Rao, J.S., Ertley, R.N., Lee, H.J., DeMar, J.C. Jr., Arnold, J.T., Rapoport, S.I. and Bazinet, R.P. 2007. n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Mol. Psychiatry, 12:36-46.
    • (2007) Mol. Psychiatry , vol.12 , pp. 36-46
    • Rao, J.S.1    Ertley, R.N.2    Lee, H.J.3    DeMar Jr., J.C.4    Arnold, J.T.5    Rapoport, S.I.6    Bazinet, R.P.7
  • 66
    • 0036301389 scopus 로고    scopus 로고
    • Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Arch
    • Rapoport, S.I. and Bosetti, F. 2002. Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Arch. Gen. Psychiatry, 59:592-6.
    • (2002) Gen. Psychiatry , vol.59 , pp. 592-596
    • Rapoport, S.I.1    Bosetti, F.2
  • 67
    • 20744445534 scopus 로고    scopus 로고
    • The Oxford-Durham study: a randomized, controlled trial of dietary supplementation with fatty acids in children with developmental coordination disorder
    • Richardson, A.J. and Montgomery, P. 2005. The Oxford-Durham study: a randomized, controlled trial of dietary supplementation with fatty acids in children with developmental coordination disorder. Pediatrics, 115:1360-6.
    • (2005) Pediatrics , vol.115 , pp. 1360-1366
    • Richardson, A.J.1    Montgomery, P.2
  • 68
    • 0036139225 scopus 로고    scopus 로고
    • A randomized double-blind, placebocontrolled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specifi c learning diffi culties
    • Richardson, A.J. and Puri, B.K. 2002. A randomized double-blind, placebocontrolled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specifi c learning diffi culties. Prog. Neuropsychopharmacol. Biol. Psychiatry, 26:233-9.
    • (2002) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.26 , pp. 233-239
    • Richardson, A.J.1    Puri, B.K.2
  • 69
    • 38049125124 scopus 로고    scopus 로고
    • n- 3 Fatty acids and mood: the devil is in the detail
    • Richardson, A.J. 2008. n-3 Fatty acids and mood: the devil is in the detail. Br. J. Nutr., 99:421-31.
    • (2008) Br. J. Nutr. , vol.99 , pp. 421-431
    • Richardson, A.J.1
  • 72
    • 36048989288 scopus 로고    scopus 로고
    • Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?
    • Ross, B.M., Senguin, J. and Sieswerda, L. 2007. Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid? Lipids in Health and Disease, 6:21.
    • (2007) Lipids in Health and Disease , vol.6 , pp. 21
    • Ross, B.M.1    Senguin, J.2    Sieswerda, L.3
  • 73
    • 33845988720 scopus 로고    scopus 로고
    • Omega-3 fatty acid defi ciency in major depressive disorder is caused by the interaction between diet and a genetically determined abnormality in phospholipid metabolism
    • Ross, B.M. 2007. Omega-3 fatty acid defi ciency in major depressive disorder is caused by the interaction between diet and a genetically determined abnormality in phospholipid metabolism. Med. Hypotheses, 68:515-24.
    • (2007) Med. Hypotheses , vol.68 , pp. 515-524
    • Ross, B.M.1
  • 74
    • 4644289020 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of gene expression
    • Sampath, H. and Ntambi, J.M. 2004. Polyunsaturated fatty acid regulation of gene expression. Nutr. Rev., 62:333-9.
    • (2004) Nutr. Rev. , vol.62 , pp. 333-339
    • Sampath, H.1    Ntambi, J.M.2
  • 75
    • 23944435868 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of genes of lipid metabolism
    • Sampath, H. and Ntambi, J.M. 2005. Polyunsaturated fatty acid regulation of genes of lipid metabolism. Ann. Rev. Nutr., 25:317-40.
    • (2005) Ann. Rev. Nutr. , vol.25 , pp. 317-340
    • Sampath, H.1    Ntambi, J.M.2
  • 77
    • 27244438712 scopus 로고    scopus 로고
    • Regulation of intracellular calcium levels by polyunsaturated fatty acids, arachidonic acid and docosahexaenoic acid, in astrocytes: possible involvement of phospholipase A2
    • Sergeeva, M., Strokin, M. and Reiser, G. 2005. Regulation of intracellular calcium levels by polyunsaturated fatty acids, arachidonic acid and docosahexaenoic acid, in astrocytes: possible involvement of phospholipase A2. Reprod. Nutr. Dev., 45:633-46.
    • (2005) Reprod. Nutr. Dev. , vol.45 , pp. 633-646
    • Sergeeva, M.1    Strokin, M.2    Reiser, G.3
  • 78
    • 41749090254 scopus 로고    scopus 로고
    • Anti-infl ammatory and proresolving lipid mediators
    • Serhan, C.N., Yacoubian, S. and Yang, R. 2008. Anti-infl ammatory and proresolving lipid mediators. Annu Rev. Pathol., 3:279-312.
    • (2008) Annu Rev. Pathol. , vol.3 , pp. 279-312
    • Serhan, C.N.1    Yacoubian, S.2    Yang, R.3
  • 81
    • 15044339422 scopus 로고    scopus 로고
    • Cyclooxygenases, peroxide tone and the allure of fi sh oil
    • Smith, W.L. 2005. Cyclooxygenases, peroxide tone and the allure of fi sh oil. Curr. Opin. Cell Biol., 17:174-82.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 174-182
    • Smith, W.L.1
  • 82
    • 33847054767 scopus 로고    scopus 로고
    • Omega-3 fatty acid ethyl-eicosapentaenoate attenuates IL-1beta-induced changes in dopamine and metabolites in the shell of the nucleus accumbens: involved with PLA2 activity and corticosterone secretion
    • Song, C., Li, X., Kang, Z. and Kadotomi, Y. 2007. Omega-3 fatty acid ethyl-eicosapentaenoate attenuates IL-1beta-induced changes in dopamine and metabolites in the shell of the nucleus accumbens: involved with PLA2 activity and corticosterone secretion. Neuropsychopharmacology, 32:736-44.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 736-744
    • Song, C.1    Li, X.2    Kang, Z.3    Kadotomi, Y.4
  • 83
    • 0003841783 scopus 로고    scopus 로고
    • Neuroscientifi c basis and practical applications. 2nd edition. Cambridge, U.K: Cambridge University Press
    • Stahl, S.M. 2000. Essential psychopharm acology. Neuroscientifi c basis and practical applications. 2nd edition. Cambridge, U.K: Cambridge University Press.
    • (2000) Essential psychopharm acology
    • Stahl, S.M.1
  • 85
    • 0042850504 scopus 로고    scopus 로고
    • Omega-3 fatty acids in major depressive disorder
    • Su, K.P., Huang, S.Y., Chiu, C.C. and Shen, W.W. 2003. Omega-3 fatty acids in major depressive disorder. A preliminary doubleblind, placebo-controlled trial. Eur. Neuropsychopharmacol., 13:267-71.
    • (2003) Eur. Neuropsychopharmacol. , vol.13 , pp. 267-271
    • Su, K.P.1    Huang, S.Y.2    Chiu, C.C.3    Shen, W.W.4
  • 87
    • 0028988545 scopus 로고
    • Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonicspecifi c phospholipase A2
    • Vial, D. and Piomelli, D. 1995. Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonicspecifi c phospholipase A2. J. Neurochem., 64:2765-72.
    • (1995) J. Neurochem. , vol.64 , pp. 2765-2772
    • Vial, D.1    Piomelli, D.2
  • 88
    • 7244240590 scopus 로고    scopus 로고
    • Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats
    • Wu, A., Ying, Z. and Gomez-Pinilla, F. 2004. Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. J. Neurotrauma., 21:1457-67.
    • (2004) J. Neurotrauma. , vol.21 , pp. 1457-1467
    • Wu, A.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 89
    • 0030933304 scopus 로고    scopus 로고
    • Suppression of voltage-gated L-type Ca2? currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes
    • Xiao, Y.F., Gomez, A.M., Morgan, J.P., Lederer, W.J. and Leaf, A. 1997. Suppression of voltage-gated L-type Ca2? currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes. Proc. Natl. Acad. Sci. U.S.A., 94:4182-7.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4182-4187
    • Xiao, Y.F.1    Gomez, A.M.2    Morgan, J.P.3    Lederer, W.J.4    Leaf, A.5
  • 90
    • 0030844660 scopus 로고    scopus 로고
    • Acyltransferases and transacylases involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells
    • Yamashita, A., Sugiura, T. and Waku, K. 1997. Acyltransferases and transacylases involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells. J. Biochem. (Tokyo), 122:1-16.
    • (1997) J. Biochem. (Tokyo) , vol.122 , pp. 1-16
    • Yamashita, A.1    Sugiura, T.2    Waku, K.3
  • 91
    • 32844471624 scopus 로고    scopus 로고
    • Mixture of essential fatty acids lowers test anxiety
    • Yehuda, S., Rabinovitz, S. and Mostofsky, D.I. 2005. Mixture of essential fatty acids lowers test anxiety. Nutr. Neurosci., 8:265-7.
    • (2005) Nutr. Neurosci. , vol.8 , pp. 265-267
    • Yehuda, S.1    Rabinovitz, S.2    Mostofsky, D.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.