Clonal analysis for elucidating the lineage potential of embryonic NG2 + cells

Cytotherapy

Volumn 14, Issue 5, 2012, Pages 608-620

  Ju, Pei Jun ^a   Liu, Rui ^b   Yang, Hai Jie ^c   Xia, Yin Yan ^a   Feng, Zhi Wei ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Clonal analysis; Differentiation; Transplantation

Indexed keywords

CELL SURFACE PROTEIN; CHONDROITIN SULFATE PROTEOGLYCAN 4; NESTIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEOCHONDROITIN SULFATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN CORTEX; CARTILAGE CELL; CELL CLONE; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL LINEAGE; CELL POPULATION; CELL SELECTION; CELL TRANSPLANTATION; CONTROLLED STUDY; GLIA CELL; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

EID: 84859784241     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653249.2011.651528     Document Type: Article

References (46)

1. Stallcup WB. The NG2 antigen, a putative lineage marker: immunofl uorescent localization in primary cultures of rat brain. Dev Biol. 1981;83:154-65.
2. Gallo V, Mangin JM, Kukley M, Dietrich D. Synapses on NG2-expressing progenitors in the brain: multiple functions? J Physiol. 2008;586:3767-81.
3. Nishiyama A. Polydendrocytes: NG2 cells with many roles in development and repair of the CNS. Neuroscientist. 2007;13:62-76.
4. Nishiyama A, Komitova M, Suzuki R, Zhu X. Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity. Nat Rev Neurosci. 2009;10:9-22.
5. Zhu X, Hill RA, Nishiyama A. NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord. Neuron Glia Biol. 2008;4:19-26.
6. Reynolds R, Hardy R. Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo. J Neurosci Res. 1997;47:455-70.
7. Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, et al. Development of NG2 neural progenitor cells requires Olig gene function. Proc Natl Acad Sci USA. 2006;103:7853-8.
8. Karram K, Goebbels S, Schwab M, Jennissen K, Seifert G, Steinhauser C, et al. NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse. Genesis. 2008;46:743-57.
9. Zhu X, Bergles DE, Nishiyama A. NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development. 2008;135:145-57.
10. Zhao JW, Raha-Chowdhury R, Fawcett JW, Watts C. A strocytes and oligodendrocytes can be generated from NG2- progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice. Eur J Neurosci. 2009;29:1853-69.
11. Alonso G. NG2 proteoglycan-expressing cells of the adult rat brain: possible involvement in the formation of glial scar astrocytes following stab wound. Glia. 2005;49:318-38.
12. Tatsumi K, Takebayashi H, Manabe T, Tanaka KF, Makinodan M, Yamauchi T, et al. Genetic fate mapping of Olig2 progenitors in the injured adult cerebral cortex reveals preferential differentiation into astrocytes. J Neurosci Res. 2008;86:3494-502.
13. Aguirre AA, Chittajallu R, Belachew S, Gallo V. NG2- expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus. J Cell Biol. 2004;165:575-89.
14. Belachew S, Chittajallu R, Aguirre AA, Yuan X, Kirby M, Anderson S, et al. Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J Cell Biol. 2003;161:169-86.
15. Rivers LE, Young KM, Rizzi M, Jamen F, Psachoulia K, Wade A, et al. PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci. 2008;11:1392-401.
16. Dayer AG, Cleaver KM, Abouantoun T, Cameron HA. New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J Cell Biol. 2005; 168:415-27.
17. Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G 2nd, Jiang L, et al. Identifi cation and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nat Med. 2003; 9:439-47.
18. Liu A, Han YR, Li J, Sun D, Ouyang M, Plummer MR, et al. The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci. 2007;27:7339-43.
19. Cao QL, Zhang YP, Howard RM, Walters WM, Tsoulfas P, Whittemore SR. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp Neurol. 2001;167:48-58.
20. Han SS, Kang DY, Mujtaba T, Rao MS, Fischer I. Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Exp Neurol. 2002;177:360-75.
21. Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specifi c differentiation, and preferential migration in white matter. Glia. 2004;45:1-16.
22. Lepore AC, Han SS, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. Differential fate of multipotent and lineagerestricted neural precursors following transplantation into the adult CNS. Neuron Glia Biol. 2004;1:113-26.
23. Alexanian AR, Crowe MJ, Kurpad SN. Effi cient differentiation and integration of lineage-restricted neural precursors in the traumatically injured adult cat spinal cord. J Neurosci Methods. 2006;150:41-6.
24. Barres BA, Hart IK, Coles HS, Burne JF, Voyvodic JT, Richardson WD, et al. Cell death and control of cell survival in the oligodendrocyte lineage. Cell. 1992;70:31-46.
25. Roy NS, Chandler-Militello D, Lu G, Wang S, Goldman SA. Retrovirally mediated telomerase immortalization of neural progenitor cells. Nat Protoc. 2007;2:2815-25.
26. Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, et al. EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science. 2005;310:106-10.
27. Nishiyama A, Stallcup WB. Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface. Mol Biol Cell. 1993;4:1097-108.
28. Nishiyama A, Dahlin KJ, Stallcup WB. The expression of NG2 proteoglycan in the developing rat limb. Development. 1991;111:933-44.
29. Fukushi J, Inatani M, Yamaguchi Y, Stallcup WB. Expression of NG2 proteoglycan during endochondral and intramembranous ossifi cation. Dev Dyn. 2003;228:143-8.
30. McGlashan SR, Jensen CG, Poole CA. Localization of extracellular matrix receptors on the chondrocyte primary cilium. J Histochem Cytochem. 2006;54:1005-14.
31. Baracskay KL, Kidd GJ, Miller RH, Trapp BD. NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells. Glia. 2007;55:1001-10.
32. Levine JM, Card JP. Light and electron microscopic localization of a cell surface antigen (NG2) in the rat cerebellum: association with smooth protoplasmic astrocytes. J Neurosci. 1987;7:2711-20.
33. Nishiyama A, Lin XH, Giese N, Heldin CH, Stallcup WB. Co-localization of NG2 proteoglycan and PDGF alphareceptor on O2A progenitor cells in the developing rat brain. J Neurosci Res. 1996;43:299-314.
34. Ong WY, Levine JM. A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus. Neuroscience. 1999;92:83-95.
35. Shi J, Marinovich A, Barres BA. Purifi cation and characterization of adult oligodendrocyte precursor cells from the rat optic nerve. J Neurosci. 1998;18:4627-36.
36. Scolding N, Franklin R, Stevens S, Heldin CH, Compston A, Newcombe J. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis. Brain. 1998;121:2221-8.
37. Stallcup WB, Beasley L. Bipotential glial precursor cells of the optic nerve express the NG2 proteoglycan. J Neurosci. 1987;7:2737-44.
38. Miller RH. Oligodendrocyte origins. Trends Neurosci. 1996;19:92-6.
39. Levine JM, Stincone F, Lee YS. Development and differentiation of glial precursor cells in the rat cerebellum. Glia. 1993;7:307-21.
40. Leoni G, Rattray M, Butt AM. NG2 cells differentiate into astrocytes in cerebellar slices. Mol Cell Neurosci. 2009;42: 208-18.
41. Guo F, Ma J, McCauley E, Bannerman P, Pleasure D. Early postnatal proteolipid promoter-expressing progenitors produce multilineage cells in vivo. J Neurosci. 2009;29:7256-70.
42. Tamura Y, Kataoka Y, Cui Y, Takamori Y, Watanabe Y, Yamada H. Multi-directional differentiation of doublecortinand NG2-immunopositive progenitor cells in the adult rat neocortex in vivo. Eur J Neurosci. 2007;25:3489-98.
43. Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science. 1999;283:534-7.
44. Morshead CM, Benveniste P, Iscove NN, van der Kooy D. Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med. 2002;8:268-73.
45. Pringle NP, Mudhar HS, Collarini EJ, Richardson WD. PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development. 1992;115:535-51.
46. Kronenberg G, Wang LP, Synowitz M, Gertz K, Katchanov J, Glass R, et al. Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia. J Cereb Blood Flow Metab. 2005;25:1613-24.