Multi-directional differentiation of doublecortin- and NG2-immunopositive progenitor cells in the adult rat neocortex in vivo

European Journal of Neuroscience

Volumn 25, Issue 12, 2007, Pages 3489-3498

  Tamura, Yasuhisa ^a,b,c   Kataoka, Yosky ^a,b,c   Cui, Yilong ^a,b,c   Takamori, Yasuharu ^a   Watanabe, Yasuyoshi ^b,c   Yamada, Hisao ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b Japan Science and Technology Agency   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BrdU; Cerebral cortex; Gliogenesis; Neural progenitor cells; Neurogenesis

Indexed keywords

BROXURIDINE; CELL MARKER; DOUBLECORTIN; GLUTATHIONE TRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; GLIA CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALS; BROMODEOXYURIDINE; CELL COUNT; CELL DIFFERENTIATION; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; MULTIPOTENT STEM CELLS; NEOCORTEX; NERVE TISSUE PROTEINS; NEUROPEPTIDES; PHOSPHOPYRUVATE HYDRATASE; RATS; TIME FACTORS; VERSICANS;

EID: 34347368939     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05617.x     Document Type: Article

References (32)

1. Aguirre, A. Gallo, V. (2004) Postnatal neurogenesis and gliogenesis in the olfactory bulb from NG2-expressing progenitors of the subventricular zone. J. Neurosci., 24, 10530 10541.
2. Belachew, S., Chittajallu, R., Aguirre, A.A., Yuan, X., Kirby, M., Anderson, S. Gallo, V. (2003) Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J. Cell Biol., 161, 169 186.
3. Brown, J.P., Couillard-Despres, S., Cooper-Kuhn, C.M., Winkler, J., Aigner, L. Kuhn, H.G. (2003) Transient expression of doublecortin during adult neurogenesis. J. Comp. Neurol., 467, 1 10.
4. Cameron, H.A., Woolley, C.S., McEwen, B.S. Gould, E. (1993) Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience, 56, 337 344.
5. Chittajallu, R., Aguirre, A. Gallo, V. (2004) NG2-positive cells in the mouse white and grey matter display distinct physiological properties. J. Physiol., 561, 109 122.
6. Dawson, M.R., Polito, A., Levine, J.M. Reynolds, R. (2003) NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS. Mol. Cell. Neurosci., 24, 476 488.
7. Dayer, A.G., Cleaver, K.M., Abouantoun, T. Cameron, H.A. (2005) New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J. Cell Biol., 168, 415 427.
8. Doetsch, F., Caille, I., Lim, D.A., Garcia-Verdugo, J.M. Alvarez-Buylla, A. (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell, 97, 703 716.
9. Doetsch, F., Garcia-Verdugo, J.M. Alvarez-Buylla, A. (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci., 17, 5046 5061.
10. Doetsch, F., Petreanu, L., Caille, I., Garcia-Verdugo, J.M. Alvarez-Buylla, A. (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron, 36, 1021 1034.
11. Fagel, D.M., Ganat, Y., Silbereis, J., Ebbitt, T., Stewart, W., Zhang, H., Ment, L.R. Vaccarino, F.M. (2006) Cortical neurogenesis enhanced by chronic perinatal hypoxia. Exp. Neurol., 199, 77 91.
12. Friedman, B., Hockfield, S., Black, J.A., Woodruff, K.A. Waxman, S.G. (1989) In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia, 2, 380 390.
13. Gage, F.H., Coates, P.W., Palmer, T.D., Kuhn, H.G., Fisher, L.J., Suhonen, J.O., Peterson, D.A., Suhr, S.T. Ray, J. (1995) Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl Acad. Sci. USA, 92, 11879 11883.
14. Gritti, A., Frolichsthal-Schoeller, P., Galli, R., Parati, E.A., Cova, L., Pagano, S.F., Bjornson, C.R. Vescovi, A.L. (1999) Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J. Neurosci., 19, 3287 3297.
15. Jin, K., Sun, Y., Xie, L., Peel, A., Mao, X.O., Batteur, S. Greenberg, D.A. (2003) Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum. Mol. Cell. Neurosci., 24, 171 189.
16. Kataoka, Y., Tamura, Y., Takamori, Y., Cui, Y. Yamada, H. (2006) Perineuronal germinal cells in the rat cerebral cortex. Med. Mol. Morph., 39, 28 32.
17. Keirstead, H.S., Levine, J.M. Blakemore, W.F. (1998) Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord. Glia, 22, 161 170.
18. Lois, C. Alvarez-Buylla, A. (1993) Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia. Proc. Natl Acad. Sci. USA, 90, 2074 2077.
19. Magavi, S.S., Leavitt, B.R. Macklis, J.D. (2000) Induction of neurogenesis in the neocortex of adult mice. Nature, 405, 951 955.
20. Morshead, C.M., Reynolds, B.A., Craig, C.G., McBurney, M.W., Staines, W.A., Morassutti, D., Weiss, S. van der Kooy, D. (1994) Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron, 13, 1071 1082.
21. Nacher, J., Crespo, C. McEwen, B.S. (2001) Doublecortin expression in the adult rat telencephalon. Eur. J. Neurosci., 14, 629 644.
22. Nacher, J., Pham, K., Gil-Fernandez, V. McEwen, B.S. (2004) Chronic restraint stress and chronic corticosterone treatment modulate differentially the expression of molecules related to structural plasticity in the adult rat piriform cortex. Neuroscience, 126, 503 509.
23. Nishiyama, A., Chang, A. Trapp, B.D. (1999) NG2+ glial cells: a novel glial cell population in the adult brain. J. Neuropathol. Exp. Neurol., 58, 1113 1124.
24. Nishiyama, A., Lin, X.H., Giese, N., Heldin, C.H. Stallcup, W.B. (1996) Interaction between NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells is required for optimal response to PDGF. J. Neurosci. Res., 43, 315 330.
25. Palmer, T.D., Markakis, E.A., Willhoite, A.R., Safar, F. Gage, F.H. (1999) Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J. Neurosci., 19, 8487 8497.
26. Paxinos, G. Watson, C. (1998) The Rat Brain in Stereotaxic Coordinates, 4th Edn. Academic Press, San Diego.
27. Seki, T. (2002) Expression patterns of immature neuronal markers PSA-NCAM, CRMP-4 and NeuroD in the hippocampus of young adult and aged rodents. J. Neurosci. Res., 70, 327 334.
28. Seki, T. Arai, Y. (1991) Expression of highly polysialylated NCAM in the neocortex and piriform cortex of the developing and the adult rat. Anat. Embryol. (Berl.), 184, 395 401.
29. Seri, B., Garcia-Verdugo, J.M., McEwen, B.S. Alvarez-Buylla, A. (2001) Astrocytes give rise to new neurons in the adult mammalian hippocampus. J. Neurosci., 21, 7153 7160.
30. Suzuki, S.O. Goldman, J.E. (2003) Multiple cell populations in the early postnatal subventricular zone take distinct migratory pathways: a dynamic study of glial and neuronal progenitor migration. J. Neurosci., 23, 4240 4250.
31. Tamura, Y., Kataoka, Y., Cui, Y. Yamada, H. (2004) Cellular proliferation in the cerebral cortex following neural excitation in rats. Neurosci. Res., 50, 129 133.
32. Yang, H.K., Sundholm-Peters, N.L., Goings, G.E., Walker, A.S., Hyland, K. Szele, F.G. (2004) Distribution of doublecortin expressing cells near the lateral ventricles in the adult mouse brain. J. Neurosci. Res., 76, 282 295.