Cytochrome P-450 2C9 exerts a vasoconstrictor influence on coronary resistance vessels in swine at rest and during exercise

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Zhou, Zhichao ^a   Hemradj, Veemal ^a   de Beer, Vincent J ^a   Gao, Fen ^a   Hoekstra, Maaike ^a   Merkus, Daphne ^a   Duncker, Dirk J ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Coronary blood flow; Coronary vasomotor tone; Reactive oxygen species; Sulfaphenazole

Indexed keywords

BRADYKININ; CYTOCHROME P450 2C9; INDOMETACIN; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; REACTIVE OXYGEN METABOLITE; SULFAPHENAZOLE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; CORONARY VASCULAR RESISTANCE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REST; TREADMILL EXERCISE; VASOCONSTRICTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; BRADYKININ; CORONARY CIRCULATION; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HEMODYNAMICS; HYPEREMIA; MALE; MUSCLE TONUS; NITRIC OXIDE SYNTHASE; OXYGEN CONSUMPTION; PHYSICAL CONDITIONING, ANIMAL; REACTIVE OXYGEN SPECIES; REST; SIGNAL TRANSDUCTION; SWINE; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 84859776722     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00648.2011     Document Type: Article

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