Creating an ideal "off-test mode" for rotary left ventricular assist devices: Establishing a safe and appropriate weaning protocol after myocardial recovery

Journal of Thoracic and Cardiovascular Surgery

Volumn 143, Issue 5, 2012, Pages 1176-1182

  Ando, Masahiko ^a,b   Nishimura, Takashi ^b   Takewa, Yoshiaki ^a   Kyo, Shunei ^b   Ono, Minoru ^b   Taenaka, Yoshiyuki ^a   Tatsumi, Eisuke ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; DEVICE REMOVAL; GOAT; HEART LEFT VENTRICLE WORK; HEART MUSCLE OXYGEN CONSUMPTION; LEFT VENTRICULAR ASSIST DEVICE; NONHUMAN; OFF TEST MODE PUMP WEANING; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; SAFETY; TREATMENT OUTCOME;

ANIMALS; DEVICE REMOVAL; GOATS; HEART-ASSIST DEVICES; MATERIALS TESTING; MODELS, ANIMAL; MYOCARDIAL CONTRACTION; MYOCARDIUM; OXYGEN; OXYGEN CONSUMPTION; PROSTHESIS DESIGN; RECOVERY OF FUNCTION; STROKE VOLUME; TIME FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 84859743868     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2011.07.065     Document Type: Article

References (25)

1. Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009;361:2241-51.
2. Lahpor J, Khaghani A, Hetzer R, Pavie A, Friedrich I, Sander K, et al. European results with a continuous-flow ventricular assist device for advanced heart-failure patients. Eur J Cardiothorac Surg. 2010;37:357-61.
3. Birks EJ, Tansley PD, Hardy J, George RS, Bowles CT, Burke M, et al. Left ventricular assist device and drug therapy for the reversal of heart failure. N Engl J Med. 2006;355:1873-84. (Pubitemid 44664645)
4. Dandel M, Weng Y, Siniawski H, Potapov E, Drews T, Lehmkuhl HB, et al. Prediction of cardiac stability after weaning from left ventricular assist devices in patients with idiopathic dilated cardiomyopathy. Circulation. 2008;118:S94-105.
5. Matsumiya G, Monta O, Fukushima N, Sawa Y, Funatsu T, Toda K, et al. Who would be a candidate for bridge to recovery during prolonged mechanical left ventricular support in idiopathic dilated cardiomyopathy? J Thorac Cardiovasc Surg. 2005;130:699-704. (Pubitemid 41265707)
6. Mokashi SA, Guan J, Wang D, Tchantchaleishvili V, Brigham M, Lipsitz S, et al. Preventing cardiac remodeling: the combination of cell-based therapy and cardiac support therapy preserves left ventricular function in rodent model of myocardial ischemia. J Thorac Cardiovasc Surg. 2010;140:1374-80.
7. Korf-Klingebiel M, Kempf T, Schluter KD, Willenbockel C, Brod T, Heineke J, et al. Conditional transgenic expression of fibroblast growth factor 9 in the adult mouse heart reduces heart failure mortality after myocardial infarction. Circulation. 2011;123:504-14.
8. Mano A, Nakatani T, Oda N, Kato T, Niwaya K, Tagusari O, et al. Which factors predict the recovery of natural heart function after insertion of a left ventricular assist system? J Heart Lung Transplant. 2008;27:869-74.
9. Birks EJ, George RS, Hedger M, Bahrami T, Wilton P, Bowles CT, et al. Reversal of severe heart failure with a continuous-flow left ventricular assist device and pharmacological therapy: a prospective study. Circulation. 2011;123:381-90.
10. Schima H, Vollkron M, Boehm H, Rothy W, Haisjackl M, Wieselthaler G, et al. Weaning of rotary blood pump recipients after myocardial recovery: a computer study of changes in cardiac energetics. J Thorac Cardiovasc Surg. 2004;127:1743-50. (Pubitemid 38725456)
11. Myers TJ, Frazier OH, Mesina HS, Radovancevic B, Gregoric ID. Hemodynamics and patient safety during pump-off studies of an axial-flow left ventricular assist device. J Heart Lung Transplant. 2006;25:379-83.
12. Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, et al. What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation? Intracircuit back-flow analysis in a mock circulation model. J Artif Organs. 2011;14:70-3. Epub 2011 Jan 18.
13. Ando M, Nishimura T, Takewa Y, Ogawa D, Yamazaki K, Kashiwa K, et al. A novel counterpulse drive mode of continuous-flow left ventricular assist devices can minimize intracircuit backward flow during pump weaning. J Artif Organs. 2011;14:74-9. Epub 2011 Jan 18.
14. Yamazaki K, Saito S, Kihara S, Tagusari O, Kurosawa H. Completely pulsatile high flow circulatory support with a constant-speed centrifugal blood pump: mechanisms and early clinical observations. Gen Thorac Cardiovasc Surg. 2007;55:158-62.
15. Kitamura M, Hanzawa K, Aoki K, Saitoh M, Hayashi J. Direct cardiac potential trigger for chronic control of a ventricular assist device. ASAIO J. 2001;47:302-4. (Pubitemid 32423023)
16. Ando M, Nishimura T, Takewa Y, Yamazaki K, Kyo S, Ono M, et al. Electrocardiogram- synchronized rotational speed change mode in rotary pumps could improve pulsatility. Artif Organs. 2011;35:941-7.
17. Ando M, Takewa Y, Nishimura T, Yamazaki K, Kyo S, Ono M, et al. A novel counterpulsation mode of rotary left ventricular assist devices can enhance myocardial perfusion. J Artif Organs. 2011;14:185-91.
18. Tuzun E, Eya K, Chee HK, Conger JL, Bruno NK, Frazier OH, et al. Myocardial hemodynamics, physiology, and perfusion with an axial flow left ventricular assist device in the calf. ASAIO J. 2004;50:47-53. (Pubitemid 38064000)
19. Tune JD, Gorman MW, Feigl EO. Matching coronary blood flow to myocardial oxygen consumption. J Appl Physiol. 2004;97:404-15. (Pubitemid 38802544)
20. Suga H, Hayashi T, Shirahata M. Ventricular systolic pressure-volume area as predictor of cardiac oxygen consumption. Am J Physiol. 1981;240:H39-44. (Pubitemid 11173237)
21. Ueno A, Tomizawa Y. Cardiac rehabilitation and artificial heart devices. J Artif Organs. 2009;12:90-7.
22. Nishimura T, Kyo S. High-dose carvedilol therapy for mechanical circulatory assisted patients. J Artif Organs. 2010;13:88-91.
23. Nishimura T, Kyo S. Triple-site pacing: a new supported therapy approach for bridge to recovery with a left ventricular assist system in a patient with idiopathic dilated cardiomyopathy. J Artif Organs. 2010;13:54-7.
24. Birks EJ, George RS. Molecular changes occurring during reverse remodelling following left ventricular assist device support. J Cardiovasc Transl Res. 2010; 3:635-42.
25. Elhabyan AK, Reyes BJ, Hallak O, Broce M, Rosencrance JG, Lucas BD, et al. Subendocardial ischemia without coronary artery disease: is elevated left ventricular end diastolic pressure the culprit? Curr Med Res Opin. 2004;20:773-7. (Pubitemid 38685024)