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Volumn 30, Issue 6, 2012, Pages 958-964

Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways

Author keywords

Autocrine; Growth factors; Intervertebral disc; MAPK; PI 3K Akt

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; SOMATOMEDIN C;

EID: 84859633721     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22017     Document Type: Article
Times cited : (67)

References (31)
  • 2
    • 0034753182 scopus 로고    scopus 로고
    • Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation
    • Johnson WE, Eisenstein SM, Roberts S. 2001. Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation. Connect Tissue Res 42:197-207. (Pubitemid 33040960)
    • (2001) Connective Tissue Research , vol.42 , Issue.3 , pp. 197-207
    • Johnson, W.E.B.1    Eisenstein, S.M.2    Roberts, S.3
  • 3
    • 48549088009 scopus 로고    scopus 로고
    • Growth factors in intervertebral disc homeostasis
    • Pratsinis H, Kletsas D. 2008. Growth factors in intervertebral disc homeostasis. Connect Tissue Res 49:273-276.
    • (2008) Connect Tissue Res , vol.49 , pp. 273-276
    • Pratsinis, H.1    Kletsas, D.2
  • 4
    • 0035499067 scopus 로고    scopus 로고
    • Clinical and demographic prognostic indicators for human disc cell proliferation in vitro: Pilot study
    • DOI 10.1097/00007632-200111010-00006
    • Gruber HE, Norton HJ, Leslie K, et al. 2001. Clinical and demographic prognostic indicators for human disc cell proliferation in vitro: pilot study. Spine 26:2323-2327. (Pubitemid 33043313)
    • (2001) Spine , vol.26 , Issue.21 , pp. 2323-2327
    • Gruber, H.E.1    James, N.H.2    Leslie, K.3    Hanley Jr., E.N.4
  • 5
    • 84939117432 scopus 로고
    • Stimulation of mature canine intervertebral disc by growth factors
    • Thompson JP, Oegema TR Jr, Bradford DS. 1991. Stimulation of mature canine intervertebral disc by growth factors. Spine 16:253-260.
    • (1991) Spine , vol.16 , pp. 253-260
    • Thompson, J.P.1    Oegema Jr., T.R.2    Bradford, D.S.3
  • 6
    • 36148934197 scopus 로고    scopus 로고
    • PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways
    • DOI 10.1007/s00586-007-0408-9
    • Pratsinis H, Kletsas D. 2007. PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways. Eur Spine J 16:1858-1866. (Pubitemid 350105321)
    • (2007) European Spine Journal , vol.16 , Issue.11 , pp. 1858-1866
    • Pratsinis, H.1    Kletsas, D.2
  • 7
    • 77957191785 scopus 로고    scopus 로고
    • Effect of varying osmotic conditions on the response of bovine nucleus pulposus cells to growth factors and the activation of the ERK and Akt pathways
    • Mavrogonatou E, Kletsas D. 2010. Effect of varying osmotic conditions on the response of bovine nucleus pulposus cells to growth factors and the activation of the ERK and Akt pathways. J Orthop Res 28:1276-1282.
    • (2010) J Orthop Res , vol.28 , pp. 1276-1282
    • Mavrogonatou, E.1    Kletsas, D.2
  • 8
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • DOI 10.1016/S0968-0004(01)01958-2, PII S0968000401019582
    • Brazil DP, Hemmings BA. 2001. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 26: 657-664. (Pubitemid 33042488)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.11 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 9
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • DOI 10.1038/35065000
    • Chang L, Karin M. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37-40. (Pubitemid 32225829)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 11
    • 0026565941 scopus 로고
    • Quiescence and proliferative response of normal human embryonic fibroblasts in homologous environment. Effect of aging
    • Kletsas D, Stathakos D. 1992. Quiescence and proliferative response of normal human embryonic fibroblasts in homologous environment. Effect of aging. Cell Biol Int Rep 16:103-113.
    • (1992) Cell Biol Int Rep , vol.16 , pp. 103-113
    • Kletsas, D.1    Stathakos, D.2
  • 12
    • 78349250944 scopus 로고    scopus 로고
    • Human amniotic fluid stimulates the proliferation of human fetal and adult skin fibroblasts: The roles of bFGF and PDGF and of the ERK and Akt signaling pathways
    • Chrissouli S, Pratsinis H, Velissariou V, et al. 2010. Human amniotic fluid stimulates the proliferation of human fetal and adult skin fibroblasts: the roles of bFGF and PDGF and of the ERK and Akt signaling pathways. Wound Repair Regen 18:643-654.
    • (2010) Wound Repair Regen , vol.18 , pp. 643-654
    • Chrissouli, S.1    Pratsinis, H.2    Velissariou, V.3
  • 14
    • 0037108786 scopus 로고    scopus 로고
    • Cell viability in scoliotic discs in relation to disc deformity and nutrient levels
    • (PhilaPa 1976) discussion 2227-2228
    • Bibby SR, Fairbank JC, Urban MR, et al. 2002. Cell viability in scoliotic discs in relation to disc deformity and nutrient levels. Spine (PhilaPa 1976) 27:2220-2228 discussion 2227-2228.
    • (2002) Spine , vol.27 , pp. 2220-2228
    • Bibby, S.R.1    Fairbank, J.C.2    Urban, M.R.3
  • 15
    • 0036894572 scopus 로고    scopus 로고
    • Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science
    • PhilaPa 1976
    • Boos N, Weissbach S, Rohrbach H, et al. 2002. Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine (PhilaPa 1976) 27:2631-2644.
    • (2002) Spine , vol.27 , pp. 2631-2644
    • Boos, N.1    Weissbach, S.2    Rohrbach, H.3
  • 16
    • 34548620230 scopus 로고    scopus 로고
    • The cell biology of intervertebral disc aging and degeneration
    • Zhao CQ, Wang LM, Jiang LS, et al. 2007. The cell biology of intervertebral disc aging and degeneration. Ageing Res Rev 6:247-261.
    • (2007) Ageing Res Rev , vol.6 , pp. 247-261
    • Zhao, C.Q.1    Wang, L.M.2    Jiang, L.S.3
  • 17
    • 8644224128 scopus 로고    scopus 로고
    • Growth factors and the intervertebral disc
    • DOI 10.1016/j.spinee.2004.07.028, PII S1529943004005959
    • Masuda K, An HS. 2004. Growth factors and the intervertebral disc. Spine J 4:330S-340S. (Pubitemid 39497324)
    • (2004) Spine Journal , vol.4 , Issue.6 SUPPL.
    • Masuda, K.1    An, H.S.2
  • 18
    • 0028814521 scopus 로고
    • Ingrowth of blood vessels in disc degeneration. Angiographic and histological studies of cadaveric spines
    • Kauppila LI. 1995. Ingrowth of blood vessels in disc degeneration. Angiographic and histological studies of cadaveric spines. J Bone Joint Surg Am 77:26-31.
    • (1995) J Bone Joint Surg Am , vol.77 , pp. 26-31
    • Kauppila, L.I.1
  • 19
    • 44449143395 scopus 로고    scopus 로고
    • Action of fibroblast growth factor-2 on the intervertebral disc
    • Li X, An HS, Ellman M, et al. 2008. Action of fibroblast growth factor-2 on the intervertebral disc. Arthritis Res Ther 10:R48.
    • (2008) Arthritis Res Ther , vol.10
    • Li, X.1    An, H.S.2    Ellman, M.3
  • 20
    • 78649835304 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells
    • Kim JS, Ellman MB, An HS, et al. 2010. Insulin-like growth factor 1 synergizes with bone morphogenetic protein 7-mediated anabolism in bovine intervertebral disc cells. Arthritis Rheum 62:3706-3715.
    • (2010) Arthritis Rheum , vol.62 , pp. 3706-3715
    • Kim, J.S.1    Ellman, M.B.2    An, H.S.3
  • 21
    • 39049144760 scopus 로고    scopus 로고
    • ISSLS prize winner: Repeated disc injury causes persistent inflammation
    • PhilaPa 1976
    • Ulrich JA, Liebenberg EC, Thuillier DU, et al. 2007. ISSLS prize winner: repeated disc injury causes persistent inflammation. Spine (PhilaPa 1976) 32:2812-2819.
    • (2007) Spine , vol.32 , pp. 2812-2819
    • Ulrich, J.A.1    Liebenberg, E.C.2    Thuillier, D.U.3
  • 22
    • 27944471389 scopus 로고    scopus 로고
    • Hypoxia activates MAPK activity in rat nucleus pulposus cells: Regulation of integrin expression and cell survival
    • PhilaPa 1976
    • Risbud MV, Guttapalli A, Albert TJ, et al. 2005. Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival. Spine (PhilaPa 1976) 30:2503-2509.
    • (2005) Spine , vol.30 , pp. 2503-2509
    • Risbud, M.V.1    Guttapalli, A.2    Albert, T.J.3
  • 23
    • 34548546827 scopus 로고    scopus 로고
    • MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP
    • DOI 10.1359/jbmr.070322
    • Tsai TT, Guttapalli A, Agrawal A, et al. 2007. MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/ OREBP. J Bone Miner Res 22:965-974. (Pubitemid 351339718)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.7 , pp. 965-974
    • Tsai, T.-T.1    Guttapalli, A.2    Agrawal, A.3    Albert, T.J.4    Shapiro, I.M.5    Risbud, M.V.6
  • 25
    • 39649114343 scopus 로고    scopus 로고
    • TNF-alpha induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration
    • PhilaPa 1976
    • Seguin CA, Pilliar RM, Madri JA, et al. 2008. TNF-alpha induces MMP2 gelatinase activity and MT1-MMP expression in an in vitro model of nucleus pulposus tissue degeneration. Spine (PhilaPa 1976) 33:356-365.
    • (2008) Spine , vol.33 , pp. 356-365
    • Seguin, C.A.1    Pilliar, R.M.2    Madri, J.A.3
  • 26
    • 79951901091 scopus 로고    scopus 로고
    • Fibronectin fragment activation of ERK increasing integrin alpha(5) and beta(1) subunit expression to degenerate nucleus pulposus cells
    • Xia M, Zhu Y. 2011. Fibronectin fragment activation of ERK increasing integrin alpha(5) and beta(1) subunit expression to degenerate nucleus pulposus cells. J Orthop Res 29:556-561.
    • (2011) J Orthop Res , vol.29 , pp. 556-561
    • Xia, M.1    Zhu, Y.2
  • 27
    • 70449724728 scopus 로고    scopus 로고
    • PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc
    • Cheng CC, Uchiyama Y, Hiyama A, et al. 2009. PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. J Cell Physiol 221:668-676.
    • (2009) J Cell Physiol , vol.221 , pp. 668-676
    • Cheng, C.C.1    Uchiyama, Y.2    Hiyama, A.3
  • 28
    • 14844342946 scopus 로고    scopus 로고
    • Nutrition of the intervertebral disc
    • PhilaPa 1976
    • Urban JP, Smith S, Fairbank JC. 2004. Nutrition of the intervertebral disc. Spine (PhilaPa 1976) 29:2700-2709.
    • (2004) Spine , vol.29 , pp. 2700-2709
    • Urban, J.P.1    Smith, S.2    Fairbank, J.C.3
  • 29
    • 67650577141 scopus 로고    scopus 로고
    • High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response
    • Amst
    • Mavrogonatou E, Kletsas D. 2009. High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response. DNA Repair (Amst) 8:930-943.
    • (2009) DNA Repair , vol.8 , pp. 930-943
    • Mavrogonatou, E.1    Kletsas, D.2
  • 30
    • 34249028495 scopus 로고    scopus 로고
    • The presence of pleiotrophin in the human intervertebral disc is associated with increased vascularization: An immunohistologic study
    • PhilaPa 1976
    • Johnson WE, Patterson AM, Eisenstein SM, et al. 2007. The presence of pleiotrophin in the human intervertebral disc is associated with increased vascularization: an immunohistologic study. Spine (PhilaPa 1976) 32:1295-1302.
    • (2007) Spine , vol.32 , pp. 1295-1302
    • Johnson, W.E.1    Patterson, A.M.2    Eisenstein, S.M.3
  • 31
    • 0030902669 scopus 로고    scopus 로고
    • Platelet-derived growth factor and vascular endothelial growth factor expression in disc herniation tissue: An immunohistochemical study
    • DOI 10.1007/BF01676576
    • Tolonen J, Gronblad M, Virri J, et al. 1997. Platelet-derived growth factor and vascular endothelial growth factor expression in disc herniation tissue: and immunohistochemical study. Eur Spine J 6:63-69. (Pubitemid 27143843)
    • (1997) European Spine Journal , vol.6 , Issue.1 , pp. 63-69
    • Tolonen, J.1    Gronblad, M.2    Virri, J.3    Seitsalo, S.4    Rytomaa, T.5    Karaharju, E.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.