Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Carcinogenesis

Volumn 33, Issue 4, 2012, Pages 876-885

  Choudhary, Shambhunath ^a   Sood, Shilpa ^a   Donnell, Robert L ^a   Wang, Hwa Chain R ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; ALDEHYDE DEHYDROGENASE; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TRANSCRIPTION FACTOR SP1; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CANCER STAGING; CARCINOGENICITY; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL;

EID: 84859626148     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs097     Document Type: Article

References (50)

1. Gray, J. et al. (2009) State of the evidence: the connection between breast cancer and the environment. Int. J. Occup. Environ. Health, 15, 43-78.
2. DeBruin, L. S. et al. (2002) Perspectives on the chemical etiology of breast cancer. Environ. Health Perspect., 110, 119-128.
3. Kelloff, G. J. et al. (eds.) (2005) Cancer Chemoprevention: Strategies for Cancer Chemoprevention. Vol. 2. Human Press, Totowa, NJ.
4. Mehta, R. G. (2000) Experimental basis for the prevention of breast cancer. Eur. J. Cancer, 36, 1275-1282.
5. Rudel, R. A. et al. (2007) Chemicals causing mammary gland tumors in animals signal new directions for epidemiology, chemicals testing, and risk assessment for breast cancer prevention. Cancer, 109, 2635-2666.
6. Pala, V. et al. (2009) Meat, eggs, dairy products, and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Am. J. Clin. Nutr., 90, 602-612.
7. Zheng, W. et al. (2009) Well-done meat intake, heterocyclic amine exposure, and cancer risk. Nutr. Cancer, 61, 437-446.
8. Sugimura, T. et al. (2004) Heterocyclic amines: mutagens/carcinogens produced during cooking of meat and fish. Cancer Sci., 95, 290-299.
9. Zheng, W. et al. (1998)Well-done meat intake and the risk of breast cancer. J. Natl Cancer Inst., 90, 1724-1729.
10. Sinha, R. et al. (2000) 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk. J. Natl Cancer Inst., 92, 1352-1354.
11. Zhu, J. et al. (2003) Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer. Cancer Epidemiol. Biomarkers Prev., 12, 830-837.
12. Yu, M. et al. (2002) H-ras oncogene mutations during development of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced rat mammary gland cancer. Carcinogenesis, 23, 2123-2128.
13. Moon, A. et al. (2000) H-ras, but not N-ras, induces an invasive phenotype in human breast epithelial cells: a role for MMP-2 in the H-ras-induced invasive phenotype. Int. J. Cancer, 85, 176-181.
14. Choudhary, S. et al. (2010) FK228 and oncogenic H-Ras synergistically induce Mek1/2 and Nox-1 to generate reactive oxygen species for differential cell death. Anticancer Drugs, 21, 831-840.
15. Bedard, K. et al. (2007) The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev., 87, 245-313.
16. Creton, S. K. et al. (2007) The cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine activates the extracellular signal regulated kinase mitogen-activated protein kinase pathway. Cancer Res., 67, 11455-11462.
17. Campbell, S. L. et al. (1998) Increasing complexity of Ras signaling. Oncogene, 17, 1395-1413.
18. Mei, J. et al. (2003) Transformation of noncancerous human breast epithelial cell MCF10A induced by the tobacco-specific carcinogen NNK. Breast Cancer Res. Treat, 79, 95-105.
19. Siriwardhana, N. et al. (2008) Precancerous carcinogenesis of human breast epithelial cells by chronic exposure to benzo[a]pyrene. Mol. Carcinog., 47, 338-348.
20. Siriwardhana, N. et al. (2008) Precancerous model of human breast epithelial cells induced by the tobacco-specific carcinogen NNK for prevention. Breast Cancer Res. Treat., 109, 427-441.
21. Song, X. et al. (2010) Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene. Mol. Carcinog., 49, 450-463.
22. Rathore, K. et al. (2011) Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically-induced breast cell carcinogenesis. Carcinogenesis,, 33, 174-183.
23. Yang, C. S. et al. (2009) Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer, 9, 429-439.
24. Choudhary, S. et al. (2007) Proapoptotic ability of oncogenic H-Ras to facilitate apoptosis induced by histone deacetylase inhibitors in human cancer cells. Mol. Cancer Ther., 6, 1099-1111.
25. Albini, A. et al. (1987) A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res., 47, 3239-3245.
26. Ginestier, C. et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell, 1, 555-567.
27. Olive, P. L. et al. (2006) The comet assay: a method to measure DNA damage in individual cells. Nat. Protoc., 1, 23-29.
28. Hanahan, D. et al. (2000) The hallmarks of cancer. Cell, 100, 57-70.
29. Larsson, O. et al. (1985) Consequences of parental exposure to serum-free medium for progeny cell division. J. Cell Sci., 75, 259-268.
30. Reddig, P. J. et al. (2005) Clinging to life: cell to matrix adhesion and cell survival. Cancer Metastasis Rev., 24, 425-439.
31. Datta, S. et al. (2007) Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways. Cancer Res., 67, 10286-10295.
32. Debnath, J. et al. (2005) Modelling glandular epithelial cancers in threedimensional cultures. Nat. Rev. Cancer, 5, 675-688.
33. Preston-Martin, S. et al. (1993) Epidemiologic evidence for the increased cell proliferation model of carcinogenesis. Prog. Clin. Biol. Res., 369, 21-34.
34. Adachi, Y. et al. (2008) Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6. Oncogene, 27, 4921-4932.
35. Suh, Y. A. et al. (1999) Cell transformation by the superoxide-generating oxidase Mox1. Nature, 401, 79-82.
36. Montesano, R. et al. (2005) Tumour necrosis factor alpha confers an invasive, transformed phenotype on mammary epithelial cells. J. Cell Sci., 118, 3487-3500.
37. Herbst, R. S. et al. (2000) Differential expression of E-Cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma. Clin. Cancer Res., 6, 790-797.
38. Lecureur, V. et al. (2005) ERK-dependent induction of TNFalpha expression by the environmental contaminant benzo(a)pyrene in primary human macrophages. FEBS Lett., 579, 1904-1910.
39. Sarrió, D. et al. (2008) Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res., 68, 989-997.
40. Gupta, P. B. et al. (2009) Cancer stem cells: mirage or reality? Nat. Med., 15, 1010-1012.
41. Charafe-Jauffret, E. et al. (2008) Cancer stem cells in breast: current opinion and future challenges. Pathobiology, 75, 75-84.
42. Liu, Y. et al. (2001) p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding. Carcinogenesis, 22, 851-860.
43. Rogakou, E. P. et al. (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine. J. Biol. Chem., 139, 5858-5868.
44. Cooke, M. S. et al. (2003) Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J., 17, 1195-1214.
45. Gart, J. J. et al. (1979) Statistical issues in interpretation of chronic bioassay tests for carcinogenicity. J. Natl Cancer Inst., 62, 957-974.
46. Cohrssen, J. J. et al. (1989) Risk Analysis: A Guide to Principles and Methods for Analyzing Health and Environmental Risks. Diane Publishing Co, Darby, PA.
47. Price, J. E. et al. (1990) Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res., 50, 717-721.
48. Sharkey, F. E. et al. (1979) Incidence and pathological features of spontaneous tumors in athymic nude mice. Cancer Res., 39, 833-839.
49. Hand, P. H. et al. (1987) Quantitation of Harvey ras p21 enhanced expression in human breast and colon carcinomas. J. Natl Cancer Inst., 79, 59-65.
50. Pethe, V. et al. (1999) Estrogen inducibility of c-Ha-ras transcription in breast cancer cells. Identification of functional estrogen-responsive transcriptional regulatory elements in exon 1/intron 1 of the c-Ha-ras gene. J. Biol. Chem., 274, 30969-30978.