Ginsenoside Rb1 selectively inhibits the activity of L-type voltage-gated calcium channels in cultured rat hippocampal neurons

Acta Pharmacologica Sinica

Volumn 33, Issue 4, 2012, Pages 438-444

  Lin, Zhi Ying ^a   Chen, Li Min ^a   Zhang, Jing ^a   Pan, Xiao Dong ^a   Zhu, Yuan Gui ^a   Ye, Qin Yong ^a   Huang, Hua Pin ^a   Chen, Xiao Chun ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

agatoxin IVA; conotoxin GVIA; cAMP PKA signaling pathway; ginsenoside Rb1; hippocampus; L type Ca 2+ channel; nifedipine; patch clamp technique

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; FORSKOLIN; GINSENOSIDE RB 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NIFEDIPINE; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN GVIA; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRIC POTENTIAL; EMBRYO; HIPPOCAMPUS; NERVE CELL CULTURE; NONHUMAN; PATCH CLAMP; RAT; STEADY STATE;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; GINSENOSIDES; HIPPOCAMPUS; NEURONS; PANAX; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84859568691     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.181     Document Type: Article

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