Role for substance P-based nociceptive signaling in progenitor cell activation and angiogenesis during ischemia in mice and in human subjects

Circulation

Volumn 125, Issue 14, 2012, Pages 1774-1786

  Amadesi, Silvia ^a   Reni, Carlotta ^a   Katare, Rajesh ^a   Meloni, Marco ^a   Oikawa, Atsuhiko ^a   Beltrami, Antonio P ^c   Avolio, Elisa ^c   Cesselli, Daniela ^c   Fortunato, Orazio ^b   Spinetti, Gaia ^b   Ascione, Raimondo ^a   Cangiano, Elisa ^d   Valgimigli, Marco ^d   Hunt, Stephen P ^e   Emanueli, Costanza ^a   Madeddu, Paolo ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b IRCCS MULTIMEDICA   (Italy)

^c UNIVERSITY OF UDINE   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Limb ischemia; Myocardial infarction; Neovascularization; Stem cells

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CD34 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; MORPHINE; NEUROKININ 1 RECEPTOR; SUBSTANCE P; SUBSTANCE P RECEPTOR; VASCULOTROPIN RECEPTOR 2;

ACUTE HEART INFARCTION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BONE MARROW; CELL ACTIVATION; CELL HOMING; CELL MIGRATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE PRODUCT; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; ISCHEMIA; LIMB ISCHEMIA; MALE; MOUSE; NERVE FIBER; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REPERFUSION; SENSORY NERVE CELL; STEM CELL; STEM CELL MOBILIZATION; STEM CELL TRANSPLANTATION; TRABECULAR BONE; WOUND HEALING;

ANIMALS; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; NOCICEPTION; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; RECEPTORS, NEUROKININ-1; SIGNAL TRANSDUCTION; STEM CELLS; SUBSTANCE P;

EID: 84859548724     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.089763     Document Type: Article

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