Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors

Biochemistry

Volumn 47, Issue 47, 2008, Pages 12398-12408

  Jones, Lindsay L ^a   Colf, Leremy A ^c   Bankovich, Alexander J ^c   Stone, Jennifer D ^a   Gao, Yi Gui ^a   Choi, Mui Chan ^a   Huang, Raven H ^a   Garcia, K Christopher ^b,c   Kranz, David M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; CELL MEMBRANES; CLONING; ORGANIC ACIDS; THERMAL CONDUCTIVITY OF SOLIDS; THERMODYNAMICS; VOLUMETRIC ANALYSIS;

AMINO ACID PEPTIDES; BINDING MECHANISMS; CONFORMATIONAL CHANGES; ENTHALPICALLY; HIGH AFFINITIES; ISOTHERMAL TITRATION CALORIMETRIES; KINETIC BINDINGS; T CELL RECEPTORS; T CELLS;

ELECTRIC REACTORS;

GLUTAMINYLLEUCYLSERYLPROLYLPHENYLALANYLPROLYLPHENYLALANYLASPARTYLLEUCINE; GLUTAMINYLLEUCYLSERYLPROLYLTYROSYLPROLYLPHENYLALANYLLEUCYLLEUCINE; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; PEPTIDE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AGONIST; ARTICLE; BINDING AFFINITY; BINDING KINETICS; COMPLEMENTARITY DETERMINING REGION; CONFORMATIONAL TRANSITION; ENTHALPY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; LYMPHOCYTE CLONE; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN VARIANT; RECEPTOR AFFINITY; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; THERMODYNAMICS; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; CRICETINAE; KINETICS; LIGANDS; MICE; MODELS, MOLECULAR; MUTATION; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RECEPTORS, ANTIGEN, T-CELL; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TRANSFECTION;

EID: 56749095210     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801349g     Document Type: Article

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