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Volumn 22, Issue 5, 2006, Pages 376-384

Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT)

Author keywords

Cognitive dysfunction; Elderly; Periventricular hyperintensity; Subcortical atrophy; Type 2 diabetes mellitus; White matter hyperintensities

Indexed keywords

GLUCOSE; INSULIN;

EID: 33749001980     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.632     Document Type: Article
Times cited : (142)

References (68)
  • 2
    • 13144307081 scopus 로고    scopus 로고
    • Treatment of the patient with diabetes: Importance of maintaining target HbA(1c)
    • Davidson JA. Treatment of the patient with diabetes: importance of maintaining target HbA(1c). Curr Med Res Opin 2004; 20: 1919-1927.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1919-1927
    • Davidson, J.A.1
  • 3
    • 0000291879 scopus 로고
    • Psychologic tests applied to diabetic patients
    • Miles WR, Root HF. Psychologic tests applied to diabetic patients. Arch Intern Med 1922; 30: 767-777.
    • (1922) Arch Intern Med , vol.30 , pp. 767-777
    • Miles, W.R.1    Root, H.F.2
  • 4
    • 0031025854 scopus 로고    scopus 로고
    • Is type 2 diabetes associated with an increased risk of cognitive dysfunction? A critical review of published studies
    • Strachan MW, Ewing FM, Deary IJ, et al. Is type 2 diabetes associated with an increased risk of cognitive dysfunction? A critical review of published studies. Diabetes Care 1997; 20: 438-445.
    • (1997) Diabetes Care , vol.20 , pp. 438-445
    • Strachan, M.W.1    Ewing, F.M.2    Deary, I.J.3
  • 5
    • 0032764016 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia: The Rotterdam study
    • Ott A, Stolk RP, van Harskamp F, et al. Diabetes mellitus and the risk of dementia: the Rotterdam study. Neurology 1999; 53: 1937-1942.
    • (1999) Neurology , vol.53 , pp. 1937-1942
    • Ott, A.1    Stolk, R.P.2    van Harskamp, F.3
  • 6
    • 0035479310 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
    • Luchsinger JA, Tang MX, Stern Y, et al. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol 2001; 154: 635-641.
    • (2001) Am J Epidemiol , vol.154 , pp. 635-641
    • Luchsinger, J.A.1    Tang, M.X.2    Stern, Y.3
  • 7
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia aging study
    • Peila R, Rodriguez BL, Launer LJ. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: the Honolulu-Asia aging study. Diabetes 2002; 51: 1256-1262.
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 8
    • 0036973393 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian study of health and aging
    • MacKnight C, Rockwood K, Awalt E, et al. Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian study of health and aging. Dement Geriatr Cogn Disord 2002; 14: 77-83.
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 77-83
    • MacKnight, C.1    Rockwood, K.2    Awalt, E.3
  • 9
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis Z, Wilson RS, Bienias JL, et al. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004; 61: 661-666.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3
  • 10
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus
    • Gispen WH, Biessels GJ. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 2000; 23: 542-549.
    • (2000) Trends Neurosci , vol.23 , pp. 542-549
    • Gispen, W.H.1    Biessels, G.J.2
  • 11
    • 1842734649 scopus 로고    scopus 로고
    • Modulation of memory by insulin and glucose: Neuropsychological observation in Alzheimer's disease
    • Watson GS, Craft S. Modulation of memory by insulin and glucose: neuropsychological observation in Alzheimer's disease. Eur J Pharmacol 2004; 490: 97-113.
    • (2004) Eur J Pharmacol , vol.490 , pp. 97-113
    • Watson, G.S.1    Craft, S.2
  • 12
    • 5344271854 scopus 로고    scopus 로고
    • Memory and executive function in aging and AD: Multiple factors that cause decline and reserve factors that compensate
    • Buckner RL. Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate. Neuron 2004; 44: 195-208.
    • (2004) Neuron , vol.44 , pp. 195-208
    • Buckner, R.L.1
  • 13
    • 15544373905 scopus 로고    scopus 로고
    • White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders
    • Lazarus R, Prettyman R, Cherryman G. White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders. Int J Geriatr Psychiatry 2005; 20: 274-279.
    • (2005) Int J Geriatr Psychiatry , vol.20 , pp. 274-279
    • Lazarus, R.1    Prettyman, R.2    Cherryman, G.3
  • 14
    • 0012431804 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • The Expert Committee On the Diagnosis and Classification of Diabetes Mellitus
    • The Expert Committee On the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003; 26(suppl. 1): 5-20.
    • (2003) Diabetes Care , vol.26 , Issue.SUPPL. 1 , pp. 5-20
  • 15
    • 0004235298 scopus 로고
    • American Psychiatric Association. (4th edn). American Psychiatric Association: Washington, DC
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. (4th edn). American Psychiatric Association: Washington, DC, 1994.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 16
    • 33749034567 scopus 로고    scopus 로고
    • In Kahn CR, Weir GC, King GL, Jacobson AM, Moses AC, Smith RJ (eds). Lippincott Williams & Wilkins: Boston, MA
    • Amiel SA. In Iatrogenic Hypoglycemia, Kahn CR, Weir GC, King GL, Jacobson AM, Moses AC, Smith RJ (eds). Lippincott Williams & Wilkins: Boston, MA, 2005; 671-686.
    • (2005) Iatrogenic Hypoglycemia , pp. 671-686
    • Amiel, S.A.1
  • 17
    • 17144422456 scopus 로고    scopus 로고
    • Comparison white matter lesions on T2 and FLAIR MRI in the Sydney older persons study
    • Piguet O, Ridley LJ, Grayson DA, et al. Comparison white matter lesions on T2 and FLAIR MRI in the Sydney older persons study. Eur J Neurol 2005; 12: 399-402.
    • (2005) Eur J Neurol , vol.12 , pp. 399-402
    • Piguet, O.1    Ridley, L.J.2    Grayson, D.A.3
  • 18
    • 0033950216 scopus 로고    scopus 로고
    • Cerebral white matter lesions and cognitive function: The Rotterdam scan study
    • de Groot JC, de Leeuw F-E, Oudkerk M, et al. Cerebral white matter lesions and cognitive function: the Rotterdam scan study. Ann Neurol 2000; 47: 145-151.
    • (2000) Ann Neurol , vol.47 , pp. 145-151
    • de Groot, J.C.1    de Leeuw, F.-E.2    Oudkerk, M.3
  • 19
    • 0033624404 scopus 로고    scopus 로고
    • Research criteria for subcortical vascular dementia in clinical trials
    • Erkinjuntti T, Inzitari D, Pantoni L, et al. Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 2000; 59: 23-30.
    • (2000) J Neural Transm Suppl , vol.59 , pp. 23-30
    • Erkinjuntti, T.1    Inzitari, D.2    Pantoni, L.3
  • 20
    • 84856753479 scopus 로고
    • An encephalographic ratio for estimating ventricular enlargement and cerebral atrophy
    • Evans WA. An encephalographic ratio for estimating ventricular enlargement and cerebral atrophy. Arch Neurol Psychiatry 1942; 47: 931.
    • (1942) Arch Neurol Psychiatry , vol.47 , pp. 931
    • Evans, W.A.1
  • 21
    • 0017591661 scopus 로고
    • Age and sex dependence of the size of normal ventricles on computed tomography
    • Haug G. Age and sex dependence of the size of normal ventricles on computed tomography. Neuroradiology 1977; 14: 201.
    • (1977) Neuroradiology , vol.14 , pp. 201
    • Haug, G.1
  • 22
    • 0347591880 scopus 로고
    • Computed tomographical diagnosis of brain atrophy by aging
    • Sawai F. Computed tomographical diagnosis of brain atrophy by aging. J Nara Med Assoc 1987; 38: 974-979.
    • (1987) J Nara Med Assoc , vol.38 , pp. 974-979
    • Sawai, F.1
  • 23
    • 1542774003 scopus 로고    scopus 로고
    • Assessment of brain atrophy in elderly subjects with diabetes mellitus by computed tomography
    • Ushida C, Umegaki H, Hattori A, et al. Assessment of brain atrophy in elderly subjects with diabetes mellitus by computed tomography. Geriatr Gerontol Int 2001; 1: 33-37.
    • (2001) Geriatr Gerontol Int , vol.1 , pp. 33-37
    • Ushida, C.1    Umegaki, H.2    Hattori, A.3
  • 24
    • 57049145197 scopus 로고
    • Studies of interference in serial verbal reactions
    • Stroop JR. Studies of interference in serial verbal reactions. J. Exp. Psychol. 1935; 18: 643-662.
    • (1935) J. Exp. Psychol. , vol.18 , pp. 643-662
    • Stroop, J.R.1
  • 26
    • 0020960729 scopus 로고
    • The Alzheimer's disease assessment scale; an instrument for assessing treatment efficacy
    • Mohs RC, Rosen WG, Davis KL. The Alzheimer's disease assessment scale; an instrument for assessing treatment efficacy. Psychopharmacol Bull 1983; 19: 448-450.
    • (1983) Psychopharmacol Bull , vol.19 , pp. 448-450
    • Mohs, R.C.1    Rosen, W.G.2    Davis, K.L.3
  • 27
    • 33749033177 scopus 로고    scopus 로고
    • Memory disorders in the elderly stage of dementia of the Alzheimer type: Preliminary findings
    • Ueda M, Takayama Y, Sasanuma S. Memory disorders in the elderly stage of dementia of the Alzheimer type: preliminary findings. Jpn J Neuropsychology 1996; 12: 178-186.
    • (1996) Jpn J Neuropsychology , vol.12 , pp. 178-186
    • Ueda, M.1    Takayama, Y.2    Sasanuma, S.3
  • 28
    • 0016823810 scopus 로고
    • 'Mini-mental state.' A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. 'Mini-mental state.' A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 30
    • 24944445130 scopus 로고    scopus 로고
    • Exploring cancer register data to find risk factors for recurrence of breast cancer - Application of canonical correlation analysis
    • Razavi AR, Gill H, Stal O, et al. Exploring cancer register data to find risk factors for recurrence of breast cancer - application of canonical correlation analysis. BMC Med Inform Decis Mak 2005; 22: 5-29.
    • (2005) BMC Med Inform Decis Mak , vol.22 , pp. 5-29
    • Razavi, A.R.1    Gill, H.2    Stal, O.3
  • 31
    • 11844296743 scopus 로고    scopus 로고
    • Conducting and interpreting canonical correlation analysis in personality research: A user-friendly primer
    • Sherry A, Henson RK. Conducting and interpreting canonical correlation analysis in personality research: a user-friendly primer. J Pers Assess 2005; 84: 37-48.
    • (2005) J Pers Assess , vol.84 , pp. 37-48
    • Sherry, A.1    Henson, R.K.2
  • 32
    • 0036453107 scopus 로고    scopus 로고
    • Cognitive associations of subcortical white matter lesions in older people
    • O'Brien JT, Wiseman R, Burton EJ, et al. Cognitive associations of subcortical white matter lesions in older people. Ann N Y Acad Sci 2002; 977: 436-444.
    • (2002) Ann N Y Acad Sci , vol.977 , pp. 436-444
    • O'Brien, J.T.1    Wiseman, R.2    Burton, E.J.3
  • 33
    • 0036208828 scopus 로고    scopus 로고
    • Hypertension and cerebral white matter lesions in prospective cohort study
    • de Leeuw FE, de Groot JC, Oudkerk M, et al. Hypertension and cerebral white matter lesions in prospective cohort study. Brain 2002; 125: 765-772.
    • (2002) Brain , vol.125 , pp. 765-772
    • de Leeuw, F.E.1    de Groot, J.C.2    Oudkerk, M.3
  • 34
    • 0027304103 scopus 로고
    • White matter changes in healthy elderly persons correlates with attention and speed of mental processing
    • Ylikoski R, Ylikoski A, Erkinjuntti T, et al. White matter changes in healthy elderly persons correlates with attention and speed of mental processing. Arch Neurol 1993; 50: 818-824.
    • (1993) Arch Neurol , vol.50 , pp. 818-824
    • Ylikoski, R.1    Ylikoski, A.2    Erkinjuntti, T.3
  • 35
    • 0027745804 scopus 로고
    • Neuropsychologic correlates of MRI white matter hyperintensities: A study of 150 normal volunteers
    • Schmidt R, Fazekas F, Offenbacher H, et al. Neuropsychologic correlates of MRI white matter hyperintensities: a study of 150 normal volunteers. Neurology 1993; 43: 2490-2494.
    • (1993) Neurology , vol.43 , pp. 2490-2494
    • Schmidt, R.1    Fazekas, F.2    Offenbacher, H.3
  • 36
    • 0029034159 scopus 로고
    • White matter hyperintensities on MRI in the neurological nondiseased elderly. Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home
    • Ylikoski R, Erkinjuntti T, Raininko R, et al. White matter hyperintensities on MRI in the neurological nondiseased elderly. Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home. Stroke 1995, 26: 1171-1177.
    • (1995) Stroke , vol.26 , pp. 1171-1177
    • Ylikoski, R.1    Erkinjuntti, T.2    Raininko, R.3
  • 37
    • 0033818719 scopus 로고    scopus 로고
    • The cognitive correlates of white matter abnormalities in normal aging: A quantitative review
    • Gunning-Dixon FM, Raz N. The cognitive correlates of white matter abnormalities in normal aging: A quantitative review. Neuropsychology 2000; 14: 224-232.
    • (2000) Neuropsychology , vol.14 , pp. 224-232
    • Gunning-Dixon, F.M.1    Raz, N.2
  • 38
    • 0036713743 scopus 로고    scopus 로고
    • Periventricular cerebral white matter lesions predict rate of cognitive decline
    • de Groot JC, de Leeuw FE, Oudkerk M, et al. Periventricular cerebral white matter lesions predict rate of cognitive decline. Ann Neurol 2002; 52: 335-341.
    • (2002) Ann Neurol , vol.52 , pp. 335-341
    • de Groot, J.C.1    de Leeuw, F.E.2    Oudkerk, M.3
  • 39
    • 0031800607 scopus 로고    scopus 로고
    • The behavioral neurology of cerebral white matter
    • Filley CM. The behavioral neurology of cerebral white matter. Neurology 1998; 50: 1535-1540.
    • (1998) Neurology , vol.50 , pp. 1535-1540
    • Filley, C.M.1
  • 40
    • 0042919305 scopus 로고    scopus 로고
    • Vascular syndromes of the thalamus
    • Schmahmann JD. Vascular syndromes of the thalamus. Stroke 2003; 34: 2264-2278.
    • (2003) Stroke , vol.34 , pp. 2264-2278
    • Schmahmann, J.D.1
  • 41
    • 0025611999 scopus 로고
    • Integrated phylogeny of the primate brain, with special reference to humans and their disease
    • Rapoport SI. Integrated phylogeny of the primate brain, with special reference to humans and their disease. Brain Res Brain Res Rev 1990; 15: 267-294.
    • (1990) Brain Res Brain Res Rev , vol.15 , pp. 267-294
    • Rapoport, S.I.1
  • 42
    • 0028288128 scopus 로고
    • Differential diagnosis of Alzheimer's disease with PET
    • Salmon E, Sadzot B, Maquet P, et al. Differential diagnosis of Alzheimer's disease with PET. J Nucl Med 1994; 35: 391-398.
    • (1994) J Nucl Med , vol.35 , pp. 391-398
    • Salmon, E.1    Sadzot, B.2    Maquet, P.3
  • 43
    • 0027493807 scopus 로고
    • Pathologic correlates of incidental MRI white matter signal hyperintensities
    • Fazekas F, Kleinert R, Offenbacher H, et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology 1993; 43: 1683-1689.
    • (1993) Neurology , vol.43 , pp. 1683-1689
    • Fazekas, F.1    Kleinert, R.2    Offenbacher, H.3
  • 44
    • 0036449825 scopus 로고    scopus 로고
    • White matter lesions and dementia MRI-pathological correlation
    • Udaka F, Sawada H, Kameyama M. White matter lesions and dementia MRI-pathological correlation. Ann N Y Acad Sci 2002; 977: 411-415.
    • (2002) Ann N Y Acad Sci , vol.977 , pp. 411-415
    • Udaka, F.1    Sawada, H.2    Kameyama, M.3
  • 45
    • 0036226876 scopus 로고    scopus 로고
    • The microvascular frontal-subcortical syndrome of aging
    • Pugh KG, Lipsitz LA. The microvascular frontal-subcortical syndrome of aging. Neurobiol Aging 2002; 23: 421-431.
    • (2002) Neurobiol Aging , vol.23 , pp. 421-431
    • Pugh, K.G.1    Lipsitz, L.A.2
  • 46
    • 9444268676 scopus 로고    scopus 로고
    • Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people
    • The Cardiovascular Health Study
    • Longstreth WT, Manolio TA, Arnold A, et al. The Cardiovascular Health Study. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. Stroke 1996; 27: 1274-1282.
    • (1996) Stroke , vol.27 , pp. 1274-1282
    • Longstreth, W.T.1    Manolio, T.A.2    Arnold, A.3
  • 47
    • 0345734341 scopus 로고    scopus 로고
    • Hypertension and the brain: Vulnerability of the prefrontal regions and executive functions
    • Raz N, Rodrigue KM, Acker JD. Hypertension and the brain: vulnerability of the prefrontal regions and executive functions. Behav Neurosci 2003; 117: 1169-1180.
    • (2003) Behav Neurosci , vol.117 , pp. 1169-1180
    • Raz, N.1    Rodrigue, K.M.2    Acker, J.D.3
  • 48
    • 0042845941 scopus 로고    scopus 로고
    • Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: Correlation with vascular risk factors
    • Taylor WD, MacFall JR, Provenzale JM, et al. Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors. AJR Am J Roentgenol 2003; 181: 571-576.
    • (2003) AJR Am J Roentgenol , vol.181 , pp. 571-576
    • Taylor, W.D.1    MacFall, J.R.2    Provenzale, J.M.3
  • 49
    • 0034786875 scopus 로고    scopus 로고
    • Cognitive function and infonnation processing in type 2 diabetes
    • Cosway R, Strachan MWJ, Dougall A, et al. Cognitive function and infonnation processing in type 2 diabetes. Diabet Med 2001; 18: 803-810.
    • (2001) Diabet Med , vol.18 , pp. 803-810
    • Cosway, R.1    Strachan, M.W.J.2    Dougall, A.3
  • 50
    • 12144290200 scopus 로고    scopus 로고
    • Cognitive function in Japanese elderly with type 2 diabetes mellitus
    • Mogi N, Umegaki H, Hattori A, et al. Cognitive function in Japanese elderly with type 2 diabetes mellitus. J Diabetes Complications 2004; 18: 42-46.
    • (2004) J Diabetes Complications , vol.18 , pp. 42-46
    • Mogi, N.1    Umegaki, H.2    Hattori, A.3
  • 51
    • 11844306546 scopus 로고    scopus 로고
    • Relationships between hyperglycemia and cognitive performance among adults with type 1 and type 2 diabetes
    • Cox DJ, Kovatchev BP, Gonder-Frederick LA, et al. Relationships between hyperglycemia and cognitive performance among adults with type 1 and type 2 diabetes. Diabetes Care 2005; 28: 71-77.
    • (2005) Diabetes Care , vol.28 , pp. 71-77
    • Cox, D.J.1    Kovatchev, B.P.2    Gonder-Frederick, L.A.3
  • 52
    • 0346216156 scopus 로고    scopus 로고
    • Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI
    • den Heijer T, Vermeer SE, van Dijk EJ, et al. Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia 2003; 46: 1604-1610.
    • (2003) Diabetologia , vol.46 , pp. 1604-1610
    • den Heijer, T.1    Vermeer, S.E.2    van Dijk, E.J.3
  • 53
    • 0027410286 scopus 로고
    • Diabetes mellitus and hypertension: The possible role of hyperglycemia through oxidative stress
    • Ceriello A, Quatraro A, Guigliano D. Diabetes mellitus and hypertension: the possible role of hyperglycemia through oxidative stress. Diabetologia 1993; 36: 265-266.
    • (1993) Diabetologia , vol.36 , pp. 265-266
    • Ceriello, A.1    Quatraro, A.2    Guigliano, D.3
  • 54
    • 0035407264 scopus 로고    scopus 로고
    • Pathophysiology of oxidative stress in diabetes mellitus
    • Lipinski B. Pathophysiology of oxidative stress in diabetes mellitus. J Diabetes Complications 2001; 15: 203-210.
    • (2001) J Diabetes Complications , vol.15 , pp. 203-210
    • Lipinski, B.1
  • 55
    • 0030859290 scopus 로고    scopus 로고
    • Activation of the receptor for advanced glycation end products triggers a p21 (ras) -dependent mitogen-activated protein kinase pathway regulated by oxidant stress
    • Lander HM, Tauras JM, Ogiste JS, et al. Activation of the receptor for advanced glycation end products triggers a p21 (ras) -dependent mitogen-activated protein kinase pathway regulated by oxidant stress. J Biol Chem 1997; 272: 17810-17814.
    • (1997) J Biol Chem , vol.272 , pp. 17810-17814
    • Lander, H.M.1    Tauras, J.M.2    Ogiste, J.S.3
  • 56
    • 1942520335 scopus 로고    scopus 로고
    • N epsiloncarboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease
    • Girones X, Guimera A, Cruz-Sanchez CZ, et al. N epsiloncarboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease. Free Radic Biol Med 2004; 36: 1241-1247.
    • (2004) Free Radic Biol Med , vol.36 , pp. 1241-1247
    • Girones, X.1    Guimera, A.2    Cruz-Sanchez, C.Z.3
  • 57
    • 0013615899 scopus 로고    scopus 로고
    • RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
    • Yan SD, Chen X, Fu J, et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 1996; 382: 685-691.
    • (1996) Nature , vol.382 , pp. 685-691
    • Yan, S.D.1    Chen, X.2    Fu, J.3
  • 58
    • 0029670094 scopus 로고    scopus 로고
    • β-Amyloid-mediated vasoactivity and vascular endothelial damage
    • Thomas T, Thomas G, McLendon C, et al. β-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996; 380: 168-171.
    • (1996) Nature , vol.380 , pp. 168-171
    • Thomas, T.1    Thomas, G.2    McLendon, C.3
  • 59
    • 0033945846 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress plays a key role in aging and apoptosis
    • Sastre J, Pallardo FV, Vina J. Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life 2000; 49: 427-435.
    • (2000) IUBMB Life , vol.49 , pp. 427-435
    • Sastre, J.1    Pallardo, F.V.2    Vina, J.3
  • 60
    • 0028905253 scopus 로고
    • Retinopathy as a risk factor for nonembolic stroke in diabetic subjects
    • Petitti DB, Bhatt H. Retinopathy as a risk factor for nonembolic stroke in diabetic subjects. Stroke 1995; 26: 593-596.
    • (1995) Stroke , vol.26 , pp. 593-596
    • Petitti, D.B.1    Bhatt, H.2
  • 61
    • 0029951435 scopus 로고    scopus 로고
    • Asymptomatic multiple lacunae in diabetics and non-diabetics detected by brain magnetic resonance imaging
    • Inoue T, Fushimi H, Yamada Y, et al. Asymptomatic multiple lacunae in diabetics and non-diabetics detected by brain magnetic resonance imaging. Diabetes Res Clin Pract 1996; 31: 81-86.
    • (1996) Diabetes Res Clin Pract , vol.31 , pp. 81-86
    • Inoue, T.1    Fushimi, H.2    Yamada, Y.3
  • 62
    • 0141525311 scopus 로고    scopus 로고
    • Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: Consensus paper of the EADC
    • Frisoni GB, Scheltens PH, Galluzzi S, et al. Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC. J Neurol Neurosurg Psychiatry 2003; 74: 1371-1381.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 1371-1381
    • Frisoni, G.B.1    Scheltens, P.H.2    Galluzzi, S.3
  • 63
    • 11244283689 scopus 로고    scopus 로고
    • Association between change in systolic blood pressure and cognitive decline among elderly Mexican Americans: Data from the Hispanic established population for epidemiology study of the elderly
    • Insel KC, Palmer RF, Stroup-Benham CA, et al. Association between change in systolic blood pressure and cognitive decline among elderly Mexican Americans: data from the Hispanic established population for epidemiology study of the elderly. Exp Aging Res 2005; 31: 35-54.
    • (2005) Exp Aging Res , vol.31 , pp. 35-54
    • Insel, K.C.1    Palmer, R.F.2    Stroup-Benham, C.A.3
  • 64
    • 12544254102 scopus 로고    scopus 로고
    • Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe
    • den Heijer T, Launer LJ, Prins ND, et al. Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe. Neurology 2005; 64: 263-267.
    • (2005) Neurology , vol.64 , pp. 263-267
    • den Heijer, T.1    Launer, L.J.2    Prins, N.D.3
  • 65
    • 0032564132 scopus 로고    scopus 로고
    • Prevention of dementia in randomized double-blind placebo-controlled systolic hypertension in Europe (Syst-Eur) trial
    • Forette F, Seux ML, Staessen JA, et al. Prevention of dementia in randomized double-blind placebo-controlled systolic hypertension in Europe (Syst-Eur) trial. Lancet 1998; 352: 1347-1351.
    • (1998) Lancet , vol.352 , pp. 1347-1351
    • Forette, F.1    Seux, M.L.2    Staessen, J.A.3
  • 66
    • 0034638746 scopus 로고    scopus 로고
    • Statins and the risk of dementia
    • Jick H, Zornberg GL, Jick SS, et al. Statins and the risk of dementia. Lancet 2000; 356: 1627-1631.
    • (2000) Lancet , vol.356 , pp. 1627-1631
    • Jick, H.1    Zornberg, G.L.2    Jick, S.S.3
  • 67
    • 0036186663 scopus 로고    scopus 로고
    • Serum lipoprotein levels, stain use, and cognitive function in older women
    • Kristine Y, Elizabeth BC, Feng L, et al. Serum lipoprotein levels, stain use, and cognitive function in older women. Arch Neurol 2002; 59: 378-384.
    • (2002) Arch Neurol , vol.59 , pp. 378-384
    • Kristine, Y.1    Elizabeth, B.C.2    Feng, L.3
  • 68
    • 4043085059 scopus 로고    scopus 로고
    • A prospective study of pravastatin in the elderly at risk: New hope for older persons
    • Shepherd J. A prospective study of pravastatin in the elderly at risk: New hope for older persons. Am J Geriatr Cardiol 2004; 13: 17-24.
    • (2004) Am J Geriatr Cardiol , vol.13 , pp. 17-24
    • Shepherd, J.1


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