Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11410-11421

  Havens, Courtney G ^a   Shobnam, Nadia ^a   Guarino, Estrella ^b   Centore, Richard C ^c   Zou, Lee ^c   Kearsey, Stephen E ^b   Walter, Johannes C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC RESIDUES; BINARY COMPLEXES; CELL CYCLE REGULATORS; DNA DAMAGES; LIGASES; MOLECULAR DETERMINANTS; PROLIFERATING CELL NUCLEAR ANTIGENS; PROTEIN-PROTEIN INTERACTIONS; S-PHASE; SUBSTRATE BINDING; SUBSTRATE RECOGNITION; UBIQUITIN LIGASES; UBIQUITYLATION; XENOPUS;

AMINO ACIDS; ANTIGENS; CELL PROLIFERATION; CHROMOSOMES; PROTEINS;

SUBSTRATES;

ASPARTIC ACID; CULLIN RING LIGASE 4; CYCLINE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ALIGNMENT; STRUCTURE ANALYSIS; UBIQUITINATION; XENOPUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN BINDING; SCHIZOSACCHAROMYCES; SUBSTRATE SPECIFICITY; UBIQUITIN-PROTEIN LIGASES; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 84859483427     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337683     Document Type: Article

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