A new HPLC UV validated method for therapeutic monitoring of deferasirox in thalassaemic patients

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 893-894, Issue , 2012, Pages 127-133

  De Francia, Silvia ^a   Massano, Davide ^a   Piccione, Francesca Maria ^a   Pirro, Elisa ^a   Racca, Silvia ^a   Di Carlo, Francesco ^a   Piga, Antonio ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Deferasirox; HPLC UV; Quantification; Thalassaemic patients

Indexed keywords

CALIBRATION CURVES; CHELATING AGENT; CHROMATOGRAPHIC SEPARATIONS; DEFERASIROX; EXTRACTION PROCEDURE; EXTRACTION RECOVERY; FOOD AND DRUG ADMINISTRATION; HPLC-UV; LIMIT OF DETECTION; LIMIT OF QUANTIFICATIONS; PHARMACOKINETIC STUDIES; PLASMA CONCENTRATION; PLASMA SAMPLES; PROTEIN PRECIPITATION; QUANTIFICATION; REVERSE-PHASE COLUMN; THALASSAEMIC PATIENTS; THERAPEUTIC MONITORING; ULTRAVIOLET DETECTION METHODS; VALIDATED METHODS;

CHELATION; CHROMATOGRAPHY; PATIENT MONITORING; PLASMAS;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

DEFERASIROX; FERRITIN; IMATINIB;

ADULT; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; FEMALE; FERRITIN BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; PRECIPITATION; PRIORITY JOURNAL; THALASSEMIA;

BENZOIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; FERRITINS; HUMANS; LINEAR MODELS; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; THALASSEMIA; TRIAZOLES;

EID: 84859444371     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.02.047     Document Type: Article

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