New HPLC-MS method for the simultaneous quantification of the antileukemia drugs imatinib, dasatinib, and nilotinib in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 18-19, 2009, Pages 1721-1726

  De Francia, Silvia ^a   D'Avolio, Antonio ^a   De Martino, Francesca ^a   Pirro, Elisa ^a   Baietto, Lorena ^a   Siccardi, Marco ^a   Simiele, Marco ^a   Racca, Silvia ^a   Saglio, Giuseppe ^a   Di Carlo, Francesco ^a   Di Perri, Giovanni ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Dasatinib; HPLC MS; Imatinib; Nilotinib; Quantification

Indexed keywords

DASATINIB; HPLC-MS; IMATINIB; NILOTINIB; QUANTIFICATION;

ACETONITRILE; AMINO ACIDS; CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC ACIDS; PLASMAS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

ABACAVIR; ACETONITRILE; AMODIAQUINE; DASATINIB; DIDANOSINE; EMTRICITABINE; ETHAMBUTOL; FORMIC ACID; IMATINIB; ISONIAZID; LAMIVUDINE; NILOTINIB; QUINOXALINE; RIBAVIRIN; STAVUDINE; TENOFOVIR; WATER; ZIDOVUDINE;

ACCURACY; ARTICLE; CALIBRATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ANALYSIS; DRUG BLOOD LEVEL; DRUG COMPETITION; DRUG DETERMINATION; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRECIPITATION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ANTINEOPLASTIC AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MASS SPECTROMETRY; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; SENSITIVITY AND SPECIFICITY; THIAZOLES;

EID: 66149119836     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.04.028     Document Type: Article

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